BCQs Of Human Genetics Outline:-

Q 1 The process of transfer of hereditary character from one generation to

another is known as...........?
a) Genes
b) Mutation
c) Variation
d) Genetics
e) Biology

Q2 Who is known as father of genetics ?

a) Gregor Mendel
b) Augustinian friar
c) Norman Borlaug
d) M.S Swaminathan
e) All above

Q3 Who coined the term Mutation?

a) James Watson
b) Herman Joseph Muller
c) Hugo de Vries
d) Gergor Mendel
e) None of the above

Q 4 Which term of genetics represents the potential ability of a plant cell to grow
into a complete plant?
a) Pluripotency
b) Totipotency
c) Cloning
d) Variation
e) Mutation
Q 5 Name the chromosome found in the cells which are responsible for
characters other than sex chromosomes ?
a) Autosomes
b) Genome
c) Mitochondrial chromosome
d) Y chromosome
e) X Chromosome

Q 6 What do you mean by law of dominance?

a) When offspring shows the characters of generation.
b) When Offspring of cross breed parent only show dominant characters in F1
generation.
c) When offspring of cross breed parent only show dominant characters in F2
generation.
d) In F2 generation both the character which is governed by gene are
separated
e) None of above

Q 7 A sudden change in the gene which is heritable from one generation to other
is known as ?
a) Variation
b) Cloning
c) Totipotency
d) Mutation
e) Disease

Q 8 Which plant Gregor Mendel had cross breed for his experiment ?
a) Onion plant
b) Carrot plant
c) Pea plant
d) Lily plant
e) Rose flower
Q9. Which of the following process is an exception of Mendel Law ?
a) Mutation
b) Variation
c) Cloning
d) Linkage
e) Chromosomes

Q10. If a genetic disease is transferred from a phenotypically normal but carrier

female to only some of the male progeny, the disease is
a) autosomal dominant
b) autosomal recessive
c) sex-linked dominance
d) sex-linked recessive
e) Gene alteration

Q11. Person having genotype IA IB would show the blood group as AB. This is
because of
a) pleiotropy
b) co-dominance
c) Segregation
d) incomplete dominance.
e) complete dominance

Q12. A cross between two tall plants resulted in offspring having few dwarf
plants. What would be the genotypes of both the parents ?
a) TT and Tt
b) Tt and Tt
c) TT and TT
d) Tt and It
e) Rr and RR
Q13. In a dihybrid cross, if you get 9 : 3 : 3 : 1 ratio it denotes that
a) the alleles of two genes are interacting with each other
b) it is a multigenic inheritance
c) it is a case of multiple allelism
d) the alleles of two genes are segregating independently.
e) All statement are false

Q14. Which of the following will not result in variations among siblings?
a) Independent assortment of genes
b) Crossing over
c) Linkage
d) Mutation
e) X Linked

Q15. Mendel’s Law of independent assortment holds good for genes situated on
the
a) non-homologous chromosomes
b) homologous chromosomes
c) extra nuclear genetic element
d) same chromosome.
e) Y chromosome

Q16. Occasionally, a single gene may express more than one effect. The
phenomenon is called
a) multiple allelism
b) mosaicism
c) pleiotropy
d) polygeny
e) Gene Mutation
 Q17. If a genetic disease is transferred from a phenotypically normal but carrier
female to only some of the male progeny, the disease is
a) autosomal dominant
b) autosomal recessive
c) sex-linked dominant
d) sex-linked recessive.
e) Y Linked disease

Q 18. Person having genotype IA IB would show the blood group as AB. This is
because of
a) pleiotropy
b) co-dominance
c) segregation
d) incomplete dominance.
e) Partial dominance

Q19. A cross between two tall plants resulted in offspring having few dwarf
plants. What would be the genotypes of both the parents ?
a) TT and Tt
b) Tt and Tt
c) TT and TT
d) Tt and tt
e) RR and rr

Q20. In a dihybrid cross, if you get 9 : 3 : 3 : 1 ratio it denotes that

a) the alleles of two genes are interacting with each other
b) it is a multigenic inheritance
c) it is a case of multiple allelism
d) the alleles of two genes are segregating independently
e) 6;3:3:1 donate that
Q21. Which of the following will not result in variations among siblings?
a) Independent assortment of genes
b) Crossing over
c) Linkage
d) Mutation
e) Test Cross

Q22. Mendel’s Law of independent assortment holds good for genes situated on
the
a) non-homologous chromosomes
b) homologous chromosomes
c) extra nuclear genetic element
d) same chromosome.
e) Gene Location

Q23. Occasionally, a single gene may express more than one effect. The
phenomenon is called
a) multiple allelism
b) mosaicism
c) Pleiotropy
d) Polygeny
e) Mutation

Q24. In the F2 generation of a Mendelian dihybrid cross the number of

phenotypes and genotypes are
a) phenotypes – 4; genotypes – 16
b) phenotypes – 9; genotypes – 4
c) phenotypes – 4; genotypes – 8
d) phenotypes – 4; genotypes – 9
e) Phenotype 4 ;genotype – 11
Q25. A recessive allele is expressed in
a) heterozygous condition only
b) homozygous condition only
c) F3 generation
d) both homozygous and heterozygous conditions.
e) Gene Expression

Q26 The alternate form of a gene is

A Alternate type

B Recessive character

C Dominant character

D Allele

E Chromosome

Q27 The genotypic ratio of a monohybrid cross is

A 1:2:1

B 3:1

C 2:1:1

D 9:3:3:1

E 9:3:2
Q28 The crossing of F1 to either of the parents is known as

A Test cross

B Back cross

C F1 cross

D All of the above

E None of above

Q29 Which of the following statements is true regarding the “law of

segregation”?

A Law of segregation is the law of purity of genes

B Alleles separate from each other during gametogenesis

C Segregation of factors is due to the segregation of chromosomes during

meiosis

D All of the above

E Alleles do not separate from each other during gametogenesis

Q30 Homozygosity and heterozygosity of an individual can be determined by

A Back cross

B Self-fertilization
 C Test cross

D All of the above

E Mono hybrid

Q31 Homozygosity and heterozygosity of an individual can be determined by

A Back cross

B Self-fertilization

C Test cross

D All of the above

E None of above

Q32 The smallest unit of genetic material which produces a phenotypic effect on
mutation is

A Muton

B Gene

C Recon

D Nucleic acid
E R NA

Q 33 When the activity of one gene is suppressed by the activity of a non-allelic

gene, it is known as

A Pseudo-dominance

B Hypostasis

C Epistasis

D Incomplete dominance

E Complete dominance

Q34 Cystic fibrosis is

A Sex-linked recessive disorder

B Autosomal dominant disorder

C Autosomal recessive disorder

D Sex-linked dominant disorder

E feotal disease

Q35 9:7 ratio in the F2 generation represents

 A Incomplete dominance

B Co-dominance

C Epistasis

D Complementary interaction

E Complete dominanace

Q36. A small amount of lethal mutation is always present in the population due to

A Positive selection

B Negative selection

C Frequency-dependent selection

D Mutation-selection balance

E Mutation is a change in a genetic sequence

Q37 If a plant with genotype AaBb is self-fertilized, the probability of getting

AABB genotype will be (A and B are not linked)
A ½

B ¼

C ⅛

D 1/16

E 1/10

Q38 . How many phenotypes can occur in the human blood group ABO with
alleles IA IB i?

A 2

B 3

C 4

D 1

E 6

Q39 . The geometrical device that helps to find out all the possible combinations
of male and female gametes is known as

A Bateson Square

B Mendel Square

C Punnett Square
 D Mendel’s Cube

E Triangle

Q40 . Which term represents a pair of contrasting characters?

A Heterozygous

B Homozygous

C Codominant genes

D AllelomorphsDominants

E dominants

Q41 DNA fingerprinting recognizes the differences in

(a) Satellite DNA

(b) Bulk DNA

© Repetitive DNA

(c) Both (a) and (c)

(e ) None of above

Q42 This force can stabilize a DNA double-helix

 (a) Hydrophilic sugar-phosphate groups are found on the exterior
of the helix where interaction with water occurs

(b) Hydrophobic bases are present in the interior of the helix, each
base-pair is stabilized by the same number of hydrogen bonds

© covalent base stacking interactions may take place between neighbouring

bases within the same strand in the helix

(c) Non-covalent N-glycosidic bonds may form between

nitrogenous bases in opposite strands in the helix

€ above all

Q43 The process of DNA replication is affected by an enzyme known as

(a) Mutase

(b) Ligase

© Polymerase I

(c) Ribonuclease
( e ) Helix

Q44 If the DNA strand has nitrogenous base sequence ATTGCC, the mRNA will
have?

(a) ATTGCA

(b) UGGACC

© UAACGG

(c) ATCGCC

(e ) AC TGCCc

Q44 The bases are held together in a DNA double helix by hydrogen bonds.
These bonds are

(a) Ionic bonds

(b) Covalent bonds

© Non-covalent bonds
 (c) Van der Waals forces

(e ) None of above