TCA

1-Energy that is released from glucose during respiration but not transferred to ATP bonds can be detected as

A. CO2

B. AMP

C. ADP

D. heat

E. all of above

2-Which of the following enzyme does not take part in the TCA cycle?

A.Citrate synthase

B.Iso-citrate dehydrogenase

C.Pyruvate dehydrogenase

D.Malate dehydrogenase

E. All of above

3-Which one of the enzymes is the one that tightly bounds to inner mitochondria membrane?

A) isocitrate dehydrogenase

B) succinate dehydrogenase

C) L-malate dehydrogenase

D) alfa-ketoglutarate dehydrogenase

E) citrate synthase

4- What is the name of the prosthetic group of Pyruvate Dehydrogenase enzyme?

A) FAD

B)NAD

C)Lipoamide

D)Thiamine pyrophosphate (TPP)

E)Haem

5-High cellular concentrations of what molecule would

inhibit the entry of pyruvate into the citric acid cycle?

A. Coenzyme A

B. Pyruvate

C. AMP

D. NADH
E. ATP

6-What powers the ATP synthase rotary motor ?

A. cAMP

B. GTP hydrolysis

C. Coenzyme motive force

D. H+ Gradient

E. ATP

7-How many FADH2 molecules are produced by 1 molecule of glucose?

A) 0

B) 1

C) 2

D) 3

E) 4

8-Krebs Cycle takes place in the

A) Cytplasm

B) Matrix

C) Ribosome

D) Intermmbran space

E) Krista

9-How many molecules of acetyl CoA, an acetyl group attached to 'coenzyme A,' are formed for participation in the Krebs
cycle from one single molecule of glucose?

a. 3

b. 4

c. 2

d. 5

e. 1

10-High concentrations of which molecule will inhibit pyruvate's entry into the citric acid cycle?

a. NADH

b. ATP

c. Coenzyme A

d. Pyruvate
e. acetyl CoA

11-Which of the following compounds doesn’t take place on

Tricarboxylic Acid Cycle?

A) Alpha-Ketoglutarate

B) Beta-Ketoglutarage

C) Succinyl-CoA

D) Acetyl-CoA

E) Fumarate

12-Which of the following enzyme is used more than once in the

Tricarboxylic Acid Cycle?

A) Succinyl-CoA Synthetase

B) Isocytrate dehydrogenase

C) Aconitase

D) Malate dehydrogenase

E) Succinate dehydrogenase

13-Which of the following is not connected with tricarboxylic acid cycle ?

A) Gluconeogenesis

B) Lipogenesis

C) Transamination

D) Pentose Phosphate Way

E) Oxidative Phosphorylation

14-With which product does b-hydroxy butyrate and acetoacetate enters the tricarboxylic acid cycle?

A) Acetyl CoA

B) Propionate CoA

C) Succinyl CoA

D) Malonyl CoA

E) HMG CoA

15-How many reactions that occur in the TCA cycle transfer electrons from a

substrate to an electron accepting enzyme?

a- 1

b- 2
c- 3

d- 4

e- 5

16-Which of the following is an important end product of disassembly of fatty

acids?

a- Succinate dehydrogenase

b- Acetyl CoA

c- Pyruvate

d- DNA gyrase

e- Malate

17-In TCA cycle, which enzyme tranforms from fumarate to succinate?

a) citrate synthatse

b) aconitase

c) succinyl CoA synthatse

d) succinate dehydrogenase

e) fumarase

18-Whereis the Krebs cycle carried out in eukaryotic cells?

a) lysosome

b) mitochondrial matrix

c) cytosol

d) inner membrane of mitochondria

e) endoplasmic reticulum

19-Which of the below is not required for the oxidative decarboxylation of pyruvate

to form acetyl-CoA?

A) ATP

B) CoA-SH

C) FAD

D) Lipoic acid

E) NAD

20-Which of the following is not true of the citric acid cycle?

A) All enzymes of the cycle are located in the cytoplasm, except succinate
dehydrogenase, which is bound to the inner mitochondrial membrane.

B) In the presence of malonate, one would expect succinate to accumulate.

C) Oxaloacetate is used as a substrate but is not consumed in the cycle.

D) Succinate dehydrogenase channels electrons directly into the electron transfer

chain.

E) The condensing enzyme is subject to allosteric regulation by ATP and NADH

21-Most enzymes that take part in Kreb’s cycle are located in:

A) cytoplasm

B) mitochondrial matrix

C) plasma membrane

D) inner mitochondrial membrane

E) nucleus

22-In the TCA cycle, which of the following combines with Acetyl CoA to form a 6 carbon

compound?

A) fumarase

B) glucose

C) pyruvate

D) oxaloacetate

E) thiamine

23-Choose the false option.

A) It is a cyclic pathway.

B) It produces 6NADH2

C) It is a linear pathway.

D) It occurs in the mitochondrial matrix.

E) It produces 2FADH2

24- + Cycle occurs twice for each molecule. (T/F)

+In eukaryotes, the citric acid cycle takes place in the matrix of the mitochondria. (T/F)

+Two carbons -from acetyl CoA - enter the citric acid cycle in each turn, and two carbon

dioxide molecules are released. (T/F)

Choose the correct answer.

A) T,F,F

B) T,F,T

C) T,T,T

D) F,T,T

E) F,T,F

25-I- The TCA cycle is an aerobic pathway

II- The TCA cycle is activated by Phosphorylation

III- The primary function of the TCA cycle is the oxidation of AcytelCoA to Co2

IV-The cycle is separated into two phases

Pick the correct answer:

A- I & II

B- only I

C- I, II & III

D- IV & III

E- I, II, III & IV

26-Sort the steps to the TCA chronologically (In order)

A- Hydration->Isomerization via hydration/dehydration->Creation of Citrate-

>Dehydrogenation to give NADH

B- Creation of Citrate->Hydration->Isomerization via hydration/dehydration-

>Dehydrogenation to give NADH

C- Dehydrogenation to give NADH->Hydration->Creation of Citrate->Isomerization via

hydration/dehydration

D- Creation of Citrate->Isomerization via hydration/dehydration->Hydration-

>Dehydrogenation to give NADH

E- Hydration->Creation of Citrate->Isomerization via hydration/dehydration-

>Dehydrogenation to give NADH

27- In addition to the regulators of enzyme activity within the citric acid cycle, two

enzymes outside the cycle profoundly affect its activity. Which ones?

a. Isocitrate dehydrogenase and isocitrate oxidase

b. Lactic acid dehydrogenase and pyruvate kinase

c. Acetaldehyde dehydrogenase and citrate synthase

d. Glucokinase and phosphofructokinase

e. Pyruvate carboxylase and pyruvate dehydrogenase

28-The citric acid cycle is a major source of NADH, but on occasion, an excess of citric

acid accumulates. Under those conditions, the carbons from citric acid are most

likely to wind up in the body as:

a. Glucose

b. Maltose

c. DNA

d. RNA

e. Lipid

29-How many molecules of ATPs are synthesized per NADH oxidation?

a)2

b)1

c)3

d)6

e)Non of them

30-Which of the following is involved in energy production?

a) Generation of proton gradients across membranes

b) Transport of electrons on organic molecules

c) Conversion of compounds with high energy to those of low energy

d) All of above

e) None of them

31-How many molecules of acetyl CoA, an acetyl group attached

to ‘coenzyme A’, are produced from a single molecule of

glucose for participation in the Krebs cycle?

A)2

B)3

C)1

D)4

E) O

32-High cellular concentrations of what molecule would inhibit the

entry of pyruvate into the citric acid cycle?

A)Coenzyme A
B)Pyruvate

C)AMP

D)NADH

E) ADP

33-Pyruvate Dehydrogenase is inhibited by?

A. FADH,ATP

B. Acetyl CoA,NADH

C. Pyruvate,Acetyl CoA

D. Calcium,FADH

E. Phosphatase,ATP

34-What is the sensitive isoform of phosphatase in the muscle?

A. Magnesium

B. Potassium

C. Calcium

D. Sodium

E. Chloride

35-Which statment about TCA cycle is true?

A)All reactions are catalyzed by enzymes.

B)Oxaloacetate and Acetyl-CoA inosculation and isocitrate forms.

C)4 CO2 forms for per Glucose molecule.

D)ATP forms in indirect ways.

E)3 NADH occur end of the krebs cycyle

36- a-produce of NADH b-Produce of FADH c-Produce of FADH2 d-Produce of Carbon

e-Produce of ATP

Which of them are main purpose of Krebs Cycyle?

A) a,b,c

B) a,d,e

C) d,e

D) a,c,e

E) only e

37-hat enzyme is required to oxidaze pyruvate into Acetyl COA?

A. aconitase
B.Pyruvate dehydrogenase

C.Succinyl COA synthase

D.Citrate synthase

E.Aconitase

38-Acetyl COA combines with oxaloacetate to form which 6 carbon compound?

A.Fumarte

B.Citrate

C.NADH

D.NADPH

E.İsocitrate

39-How many molecules of acetyl CoA, an acetyl group attached to ‘coenzyme A’, are produced from a

single molecule of glucose for participation in the Krebs cycle?

A) 1

B) 2

C) 3

D) 4

E) 5

40-During cellular respiration, where is NADH produced?

A) The mitochondrial intermembrane space

B) The nucleus

C) The endoplasmic reticulum

D) The cytosol

E) The cytosol and mitochondrial matrix

41-For each molecules of gulecose,how many times does the TCA cycle proceed?

a)3

b)1

c)4

d)2

e)0

42-Acetyl coa is ....... carbon compound

a)1

b)2
c)3

d)4

e)0

43-Which of the following compounds have six carbon?

a) Succinyl CoA

b) Succinate-Succinyl CoA

c) Malate-Fumate

d) Oxatoacetate-Citrate

e) Citrate- Isocitrate

44-Which statement about TCA is not correct?

a) Succinate CoA synthetase responsible for GTP synthesis

b) Acetyl CoA is a product of TCA reaction

c) Isocitrate dehydrogenase enzyme make oxidative decarbxylation reaction

d) Fumarase need H2O for reaction

e) Net reaction of TCA have 3 NADH

45-Which reaction in the citric acid cycle is not reversible ?

A)Succinic dehydrogenase

B)Succinyl-CoA synthetase

C)Citrate synthase

D)Malate

E)Fumarase

46-By which enzyme the pyruvate is converted to Acetyl CoA ?

A)Pyruvate decarboxylase

B)Pyruvate dehydrogenase

C)Acetyl dehydrogenase

D)Lactate dehydrogenase

E)Isocitrate dehydrogenase

47-Which one is wrong about TCA?

A) This cycle is found in mitochondria and is located close to ETZ.

B) The reduced enzymes synthesized in TCA are oxidized in ETZ.

C) The TCA cycle is an anerobic way.

D) Requires O2 as the last electron acceptor.

E) In the TCA cycle, oxaloacetate first combines with the acetyl group of acetyl CoA.

48-1- Each pair of cycles consists of four pairs of electrons.

2- Three pairs of electrons reduce NAD to NADH

3- Oxidation of NADH in the electron transport chain causes the formation of approximately

3 ATPs.

4- It causes 2 ATP formation to oxidize FADH2

Which one is ora re true?

A) Only 1

B) 1 and 2

C) 1 2 and 3

D) 1 and 4

E) 1 2 3 and 4

49-Which step in Citric Acid Cycle we produce H2O ?

A)CitrateIsocitrate

B) isocitrate  α –ketogluterate

C)Succinyl Co-A  Succinate

D) Fumarate  Malate

E) Malate  Oxaloacetate

50-Which enzyme do we use when redox reaction of Fumate to Malate?

A)Citrate synthase

B)Aconitase

C)Succinate Dehydrogenase

D)Fumarase

E) Malate Dehydoxygenase

51-Which of the following is not included in the products in the net reaction of the tricarboxylic acid cycle?

a)CoASH
b)NADH
c)NAD+
d)FADH2
e)GTP

52-Which of the substances in the tricarboxylic acid cycle does not have 4 carbon atoms?
a)succinate
b)fumarate
c)citrate
d)malate
e)oxaloacetate

53-How many ATP is synthesized during Tricarboxylic Acid Cycle?

A.11

B.21

C.15

D.13

E.12

54-High concentrations of which molecule inhibit the entry of pyruvate into TCA cycle?

A.AMP

B.NADH

C.Pyruvate

D.Coenzyme A

E.Oxaloacetate

55-If the citric acid cycle overstimulated,the body will produce too

much … .Which molecule is true following the statement ?

A)Glucose

B)Carbon dioxide

C)Oxygen

D)Acetyl CoA

E)Pyruvate

56-In what for does the product of glycolysis enter the tricarboxylic

acid cycle ?

A)Glucose

B)Co2

C)Pyruvate

D)Acetyl CoA

E)NADH

57-How many molecules of acetyl CoA, an acetyl group attached to 'coenzyme A,' are

formed for participation in the Krebs cycle from one single molecule of glucose?
a. 3

b. 4

c. 2

d. 5

e. 1

58-High concentrations of which molecule will inhibit pyruvate's entry into the citric acid

cycle?

a. NADH

b. ATP

c. Coenzyme A

d. Pyruvate

e. acetyl CoA

59-which of the following combines with Acetyl CoA

to form a 6 carbon compound?

A-Glucose

B-Thiamine

C-Succinate

D-Oxaloacetate

E-Pyruvate

60-What is the responsability of the aconitase enzyme ?

A-Isomerization

B-Assembly

C-Polymerization

D-Degradation

E-Dehydrogenase

61-Which step and enzyme matching is false for Tricarboxylic Acid Cycle?

A) Citrate synthase = C-C bond formation to make citrate

B) Aconitase = Isomerization via de/rehydration

C) Succinate thiokinase = Substrate-level phosphorylation to give GTP

D) Succinate dehydrogenase = Dehydrogenation to give reduced FADH2

E) Fumarase = Dehydration
62-Which of the below happen(s) in the conversion of Pyruvate to Acetyl-CoA?

l. Pyruvate loses one carbon atom with the release of carbon dioxide.

ll. During the breakdown of pyruvate, electrons are transferred to NAD+ to produce NADH.

lll. 1 ATP is produced for preparation to tricarboxylic acid cycle.

A) Only l

B) Only ll

C) Only lll

D) l and ll

E) l, ll and lll

63-How many molecules of acetyl CoA, an acetyl group attached to ‘coenzyme A’, are

produced from a single molecule of glucose for participation in the Krebs cycle?

A: 2

B: 1

C: 3

D: 4

E: 5

64- What is the approximate total yield of ATP that is produced via the Krebs cycle and

subsequent oxidative phosphorylation of a single molecule of acetyl CoA?

A: 32

B: 10

C: 20

D: 16

E: 12

65-Inwhich form does the product of glycolysis enter the TCA cycle?

A. AcetylCoA

B. Pyruvate

C. NADH

D. Glucose

E. Citrate

66-The first intermediate in TCA cycle is…

A. Succinate

B. Fumerate

C. Citrate

D. Malate

E. a-Ketoglutarate

67-Which of the following statements are true about tricarboxylic acid cycle?

1-The pathway is known as krebs cycle

2-Located in the mitochondrial matrix

3-Substrate level phosphorylation occurs during cycle

A) only 1 B) 1, 2 C) 2, 3 D) only 3 E) 1, 2, 3

68-Which of the following statements are true in a single turn of the tricarboxylic acid cycle?

1-Two molecules of carbon dioxide are released

2-Two molecule of ATP is produced

3-Three molecules of NADH and one molecule of FADH2 are generated

A) only 1 B) 1, 2 C) only 2 D) 1, 3 E) 1, 2, 3

69-Polysaccharides, fats and proteins break down into metabolites of __________________

a) Glycolysis

b) TCA cycle

c) RNA repair

d) Membrane synthesis

E)Gluconeogenesis

70-In the TCA cycle, which of the following combines with Acetyl CoA to form a 6 carbon compound?

a) oxaloacetate

b) glucose

c) pyruvate

d) thiamine

6)succinate

71-Why is the TCA cycle the central pathway of metabolism of the cell?

A. It occurs in the canter of the cell

B. Its intermediates are commonly used by other metabolic reactions

C. All other metabolic pathways depend upon it

D. None of the above

E. All of them

72-Energy that is released from glucose during respiration but not transferred to ATP bonds can be detected as?

A-Co2

B-AMP

C-ADP

D-Heat

E-ATP

73-In a eukaryotic cell, most of the enzymes of the citric acid cycle are located in the:

A) mitochondrial matrix

B) inner mitochondrial membrane

C)intermembrane space

D)outer mitochondrial membrane

E)cytosol

74-Pyruvate, the end product of glycolysis, enters the citric acid cycle after it has been converted to:

A)acetaldehyde

B)lactic acid

C)acetic acid

D)acetyl-CoA

E)none of the above

75-How many molecules of acetyl CoA, an acetyl group attached to ‘coenzyme A’, are produced

from a single molecule of glucose for participation in the Krebs cycle?

A) 1

B) 2

C) 3

D) 4

E) 5

76-High cellular concentrations of what molecule would inhibit the entry of pyruvate into the citric

acid cycle?

A) Coenzyme A
B) Pyruvate

C) AMP

D) NADH

E) ADP

77-The following reactions in the citric acid cycle are all reversible except ?

a) Citrate synthase

b) Fumarase

c) Succinic dehydrogenase

d) Succinyl-CoA synthetase

e) none of the above

78-the first compound that is oxidized in the citric acid cycle is

a) oxaloacetate

b) malate

c) Isocitrate

d) succinyl CoA

e) succinate

79-In addition to the regulators of enzyme activity within the citric acid cycle, two enzymes outside

the cycle profoundly affect its activity. Which ones?

a. Isocitrate dehydrogenase and isocitrate oxidase

b. Lactic acid dehydrogenase and pyruvate kinase

c. Acetaldehyde dehydrogenase and citrate synthase

d. Glucokinase and phosphofructokinase

e. Pyruvate carboxylase and pyruvate dehydrogenase

80-Oxaloacetic acid can pass into the mitochondrial matrix if it is first converted into:

a. Glucose

b. Malic acid

c. Glucose-6-phosphate

d. Acetyl-CoA

e. Succinic acid

81-High cellular concentrations of what molecule would

inhibit the entry of pyruvate into the citric acid cycle?

A) NADH

B)Coenzyme A

C) Pyruvate

D) AMP

E) CO2

82-The two main purposes of the citric acid cycle are:

A) synthesis of citrate and gluconeogenesis.

B) degradation of acetyl-CoA to produce energy and to supply precursors for anabolism.

C) degradation of pyruvate to produce energy and to supply precursors for anabolism.

D) degradation of glucose to produce energy and to supply precursors for anabolism.

E) degradation of pyruvate to produce energy and to synthesize oxaloacetate for gluconeogenesis

83-How many reactions that occur in the TCA cycle

transfer electrons from a substrate to an electron

accepting enzyme?

a) 1

b) 2

c) 3

d) 4

e) 5

84-Acetyl CoA is a _____________ carbon compound.

a) 1

b) 2

c) 3

d) 4

e) 5

85-I.CO2

II.FADH2

III.ATP (2 molecule)

IV.NADH

Which of these are the products of TCA cycle?

A) II and III B) I and IV C) I and III D) I, II and III E) all

86-I. Citric acid is formed in citrate synthase reaction from oxaloacetate and acetyl-CoA.

II. CO2 is not one of the products of TCA cycle.

III. Pyruvate turns into acetyl-CoA with pyruvate dehydrogenase.

Check whether above statements are true or false.

A) I. False II. True III. True

B) I. True II. False III. True

C) I. False II. False III. True

D) I. True II. False III. False

E) I. True II. True III. True

87-One molecule of acetyl-CoA yields what energy-rich molecules when metabolized in the TCA cycle?

A. 3 NADH,1 FADH2 and 1 GTP

B. 2 NADH and 1 ATP

C. 2 NADH, 2 FADH2 and 1 GTP

D. 1 FADH2 and 1 GTP

E. 2 NADH and 1 GTP

88-Which molecule is pyruvate converted to just before it enters the TCA cycle?

A. acetaldeyhde

B. lactic acid

C. acetic acid

D. acetyl-CoA

E. none of the above

89-How many molecules of acetyl CoA, an acetyl group attached to

‘coenzyme A’, are produced from a single molecule of glucose for

participation in the Krebs cycle?

a. 1

b. 2

c. 4

d. 3

e. 5

90-In a eukaryotic cell, most of the enzymes of the citric acid cycle are
located in the..

a. mitochondrial matrix

b. inner mitochondrial membrane

c. intermembrane space.

d. outer mitochondrial membrane

e. Cytosol.

91-Which of the following is also known as Krebs cycle?

a) Electron transport chain

b) Glycolysis

c) TCA cycle

d) DNA Replication

e) Glycogenolysis

92-How many reactions that occur in the TCA cycle

transfer electrons from a substrate to an electron

accepting enzyme?

a) 1

b) 2

c) 3

d) 4

e) 5

93-How many reactions that occur in the TCA cycle transfer electrons

from substrate to an electron accepting enzyme?

a)1

b)2

c)3

d)4

e)none of above

94-Which of the following is an important end product of disassembly of fatty acids?

a)Acetyl CoA

b)Succinate dehydrogenase

c)pyruvate
d)DNA gyrase

e)succinate

95- In a eukaryotic cell most of the enzymes of the Citric Acid Cycles are located in the:

a. mitochondrial Matrix

b. inner mitochondrial membrane

c. intermembrane Space

d. outermitochondrial membrane

e. cytosol

96-Pyruvate, the end product of glycolysis, enters the citric acid cycle after it has been converted to:

a. Acetaldehyde

b. Lactic acid

c. Acetic acid

d. Acetyl-CoA

e. None of the above

97-Energy that is released from glucose during respiration but

not transferred to ATP bonds can be detected as:

a- H 2 O.

b- CO 2 .

c- ADP.

d- turgor pressure.

e- heat.

98-The TCA cycle is involved in:

a- generation of energy from pyruvate.

b- synthesis of amino acids.

c- degradation of amino acids.

d- synthesis of fatty acids.

e- all of the above.

99-Facultative anaerobs have metabolic processes that allow them to:

A) Generate energy by growing in the presence of oxygen.

B) Use oxygen as an electron acceptor but also protect themselves against molecular
oxygen.

C) Protect themselves against atmosphere oxygen but also carry out fermentation.

D) Have an absolute requirement formolecular oxygen.

E) Use only hydrogen peroxide as an electron acceptor.

100-Which of the following is wrong regarding tricarboxylic acid cycle?

A) Pyruvate and glucose can turn into each other.

B) TCA cycle is an aerobic pathway.

C) TCA is amphibolic reaction.

D) In the multienzyme complex, side reactions are few.

E) Lipoic acid covalently linked to enzyme.

101-What is the alternate energy source when we don’t have sufficient

energy from carbs ?

a) Aldehyde

b) Protein

c) Alcohol

d) Lipid

e) Ketone

102-Whatdoes pyruvate become under anaerobic conditions ?

a) Ethanol

b) Acetyl CoA

c) Acetaldehyde

d) Lactate

e) Glucogen

103-How are electrons from the citric acid cycle for use in the electon transport chain?

A)Reduction of ATP and GTP.

B)Reduction of NAD and FAD.

C)Oxidation of NAD and FAD.

D)Oxidation of ATP and GTP.

E)Reduction of ATP and NAD

104-High cellular concentrations of what molecule inhibit the entry of pyruvate into the citric
acid cycle?

A) Coenzyme A

B) Pyruvate

C) ADP

D)NADH

E)AMP

105-In Kreb’s cycle :

a) Energy is stored in the form of ATP

b) Energy is stored in the form of ADP

c) Energy is liberated from ADP

d) Energy is liberated from ATP

e) none is correct

106-During one Kreb’s cycle number of carbon dioxide (Co2) ,

molecules released is :

a) 1

b) 2

c) 3

d) 4

e) 5

107-Which enzyme is needed in order to make Citrate from Acetyl-CoA?

a) Fumarase

b) Succinate dehydrogenase

c) Citrate synthase

d) Succinyl-CoA synthetase

e) Malate dehydrogenase

108-Inwhich reaction is GTP produced?

a)Between Succinyl CoA and Succinate

b) Between Isocitrate and -ketoglutarate

c) Between Succinate and Fumarate

d) Between Fumarate and Oxaloacetate

e) Between Citrate and Isocitrate

109-In a eukaryotic cell, most of the enzymes of the citric acid cycle are located in the

A-mitochondrial matrix.

B-inner mitochondrial membrane.

C-intermembrane space.

D-outer mitochondrial membrane.

E-cytosol.

110-Energy that is released from glucose during respiration but not transferred to ATP bonds can be detected as:

A-H2O

B-CO2

C-ADP

D-turgor pressure

E-heat

111-Which of the following enzymes converts citrate to isocitrate?

A-) Succinate dehydrogenase

B-) Fumarase

C-) Aconitase

D-) Malate dehydrogenase

E-) Citrate synthase

112-How many CO2 is produced in one turn of the citric acid cycle?

A-) 1

B-) 2

C-) 3

D-) 4

E-) 5

113-Which step of Tricarboxylic acid cycle has complex similar to pyruvate dehydrogenase complex?

a) Step 8

b) Step 3

c) Step 3&4

d) Step 4

e) Step 5
114- In which step , TPP (thiamine pyrophosphate) has not an effect?

a) First step of alcoholic fermentation

b) Step 1 of enzyme 1 in acetyl-coA production

c) Step 5 of tricarboxylic acid cycle

d) Step 2 of enzyme 1 in acetyl-coA production

e) Step 4 of tricarboxylic acid cycle (enzyme 1)

115-How much carbondioxide has been released in Tricarboxylic Acid Cycle?

A)1

B)2

C)3

D)4

E)5

116-Which of the following combines with Acetyl CoA to form citrate?

A)Succinyl CoA

B)Fumarate

C)Succinate

D)Oxaloacetate

E)Malate

117-which statement is incorrect for TCA cycle ?

a) anaerobic pathway

b) acetyl CoA oxidized to CO2

c) aerobic pathway

d) synthesis of cholesterol and steroid

e) the Acetyl CoA produced in Cytosol

118-which is the total yield of ATP in TCA cycle in Eukaryotic cells ?

a) 30

b) 32

c) 34

d) 36

e) 38
119-Pyruvate, the end product of glycolysis, enters the citric acid cycle after it has been converted to

A). Acetaldehyde

B). Lactic acid

C). Acetic acid

D). Acetyl-CoA

E). None of the above

120-In a eukaryotic cell, most of the enzymes of the citric acid cycle are located in the

A). mitochondrial matrix

B). inner mitochondrial membrane

C). intermembrane space

D). outer mitochondrial membrane

E). cytosol

121-Which step of citric acid cycle has hydration?

A) step 1

B) step 4

C) step 7

D) step8

E) step 2

122-how many NADH produced in one turn of citric acid cycle?

A) 4

B) 1

C) 3

D) 2

E) 0

1-D 2-C 3-B 4-D 5-D 6-D 7-B 8-B 9-C 10-A 11-A 12-C 13-D 14-A 15-D 16-B 17-D
18-B 19-A 20-A 21-B 22-D 23-C 24-C 25-A 26-D 27-E 28-E 29-C 30-D 31-A 32-D
33-B 34-C 35-A 36-D 37-B 38-B 39-B 40-E 41-D 42-B 43-E 44-B 45-C 46-B 47-C
48-E 49-D 50-E 51-C 52-C 53-E 54-B 55-B 56-D 57-C 58-A 59-D 60-A 61-E 62-D
63-A 64-B 65-A 66-C 67-E 68-D 69-B 70-A 71-B 72-D 73-A 74-D 75-B 76-D 77-A
78-C 79-E 80-B 81-A 82-B 83-D 84-B 85-E 86-B 87-A 88-D 89-B 90-A 91-C 92-D
93-D 94-A 95-A 96-D 97-E 98-E 99-B 100-A 101-E 102-D 103-B 104-D 105-A
106-B 107-C 108-A 109-A 110-E 111-C 112-B 113-D 114-C 115-B 116-D 117-A
118-A 119-D 120-A 121-C 122-C