Biostatistics Problems
Biostatistics Problems
Age 23 24 25 26 28 29 31 35 40
B.P 65 60 62 70 70 73 75 83 90
6. Systolic blood pressure of six hypertensive patients were 183, 179, 165. 190, 175 and 180 m.m
of Hg. After administration of particular drug for one week the B.P.s were 187, 175, 150, 180,
180 and 170 m.m of Hg respectively. Test any significant difference between before and after
treatment. t (0.01 ,5) =4.03
7. A drug was administered to 10 patients and the increments in their blood pressures were
recorded to be 6, 3, -2, 4, -3, 4, 6, 0, 0, 2. Is tt reasonable to believe that the drug has no effect
on change of blood pressure? Use 5% significance level and assume that for 9 degrees of
freedom. t (0.05, 9) = 2.26
8. Calculate the mid- year population for the year 2015 by arithmetic progression method.
a. Population of city as per 2001 census - 1,70,000
b. Population of city as per 2011 census - 2,00,000
9. 2000 smokers and 1000 non- smokers were followed up. Lung cancer developed in 120 smokers
and 20 non-smokers. Find if there is any significant association between smoking and effect on
, ed d5% ofsignificanceis3.84)
lung cancer. (Chi squared tabulated value at 1 degree of ,re om an °
1O. One thousand students in a college were graded according to their IQ and the economic
conditions of their homes. Use chi square lest lo find out whether there is any significant
association between economic cond~ions al home and IQ of students. (Chi squared tabulated
value at 1 degree of freedom and 5% of significance is 3.84)
IQ-Hlth I IQ
_,__ _
IQ-Low
12. For the following demographic data, calculate Crude birth rate, crude death rate, Infant
mortality rate and maternal mortality ratio
a. Midyear population - 1,00,000
b. No. of live births - 2500
c. No. of deaths - 900
d. No. of infant deaths - 150
e. No. of maternal deaths - 8
13.A village has midyear population of 100,000 and1000 under five-year children; the coverage of
measles vaccine is 60%. Following a case of measles 260 children developed measles and 130
died due to measles. Calculate the morbidity rate, cause specific death rate. secondary attack