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ABNORMAL LABOR
Definitions
Time limits and progress milestones have been identified
that define normal labor. Failure to meet these normal labour milestones defines abnormal labor, which suggests an increased risk of an unfavorable outcome Dystocia of labor is defined as difficult labor or abnormally slow progress of labor. Other terms that are often used interchangeably with dystocia are dysfunctional labor, failure to progress (lack of progressive cervical dilatation or lack of descent), and cephalopelvic disproportion (CPD).
Abnormal Labor Indicators
Indication Nullipara Multipara
Prolonged latent phase >20 h >14 h
Average second stage 50 min 20 min
Prolonged second stage without (with) epidural >2 h (>3 h) >1 h (>2 h)
Protracted dilation <1.2 cm/h <1.5 cm/h
Protracted descent <1 cm/h <2 cm/h
Arrest of dilation* >2 h >2 h
Arrest of descent* >2 h >1 h
Prolonged third stage >30 min >30 min
Abnormal labor constitutes any findings that fall outside
the accepted normal labor curve. In general, abnormal labor is the result of problems with one of the 3 P' s. Passenger (infant size, fetal presentation [occiput anterior, posterior, or transverse]) Pelvis or passage (size, shape, and adequacy of the pelvis) Power (uterine contractility)
Epidemiology
Of all cephalic deliveries, 8-11% are complicated by an
abnormal first stage of labor. Dystocia occurs in 12% of deliveries in women without a history of prior cesarean delivery. Dystocia may account for as many as 60% of cesarean deliveries
Etiology
Prolonged latent phase: A prolonged latent phase is
defined as exceeding 20 hours in patients who are nulliparas or 14 hours in patients who are multiparas. The most common reason for prolonged latent phase is entering labor without substantial cervical effacement. Power: Power is defined as uterine contractility multiplied by the frequency of contractions. Montevideo units (MVUs) refer to the strength of contractions in millimeters of mercury multiplied by the frequency per 10 minutes as measured by intrauterine pressure transducer. The uterine contraction pattern should repeat every 2-3 minutes. The uterine contractile force produced must exceed 200 MVUs/10 min for active labor to be considered adequate. For example, 3 contractions in 10 minutes that each reach a peak of 60 mm Hg are 60 X 3 = 180 MVUs. An arrest disorder of labor cannot be diagnosed until the patient is in the active phase and the contraction pattern exceeds 200 MVUs for 2 or more hours with no cervical change. Extending the minimum period of oxytocin augmentation for active-phase arrest from 2 up to 4 hours may be considered as long as fetal reassurance is noted with fetal heart rate monitoring. Pelvis or the size of the passageway inhibiting delivery : The shape of the bony pelvis (eg, anthropoid or platypelloid) can result in abnormal labor. A patient who is extremely short or obese, or who has had prior severe trauma to the bony pelvis, may also be at increased risk of abnormal labor. Abnormal labor could also be secondary to the passenger, the size of the infant, and/or the presentation of the infant. In addition to problems caused by the differential in size between the fetal head and the maternal bony pelvis, the fetal presentation may include asynclitism or head extension. Asynclitism is malposition of the fetal head within the pelvis, which compromises the narrowest diameter through the pelvis. Fetal macrosomia and other anomalies (including hydrocephalus, encephalocele, fetal goiter, cystic hygroma, hydrops, or any other abnormality that increases the size of the infant) are likely to cause deviation from the normal labor curve. Other factors include either a low-dose epidural or combined spinal-epidural anesthetics that minimize motor block and may contribute to a prolonged second stage. These have also been associated with an increase in oxytocin use and operative vaginal delivery. Intravenous oversedation has also been implicated as prolonging labor in both the latent and active phases.
Pathophysiology
A prolonged latent phase may result from oversedation or
from entering labor early with a thickened or uneffaced cervix. It may be misdiagnosed in the face of frequent prodromal contractions. Protraction of active labor is more easily diagnosed and is dependent upon the 3 P’s. The first P, the passenger, may produce abnormal labor because of the infant's size (e.g. macrosomia) or from malpresentation. The second P, the pelvis, can cause abnormal labor because its contours may be too small or narrow to allow passage of the infant. Both the passenger and pelvis cause abnormal labor by a mechanical obstruction, referred to as mechanical dystocia With the third P, the power component, the frequency of uterine contraction may be adequate, but the intensity may be inadequate. Disruption of communication between adjacent segments of the uterus may also exist, resulting from surgical scarring, fibroids, or other conduction disruption. Whatever the cause, the contraction pattern fails to result in cervical effacement and dilation. This is called functional dystocia. Uterine contractile force can be quantified by the use of an intra-uterine pressure catheter. Use of this device allows for direct measurement and calculation of uterine contractility per each contraction and is reported in Montevideo units (MVUs). For uterine contractile force to be considered adequate, the force produced must exceed 200 MVUs during a 10- minute contraction period. Arrest disorders cannot be properly diagnosed until the patient is in the active phase and had no cervical change for 2 or more hours with the contraction pattern exceeding 200 MVUs. Uterine contractions must be considered adequate to correctly diagnose arrest of dilation
Clinical manifestation:
History
Evaluate every pregnant patient who presents with
contractions in the labor and delivery unit. Any patient in labor is at risk for abnormal labor regardless of the number of previous pregnancies or the seemingly adequate dimensions of the pelvis. Plot the progress of any patient in labor, and evaluate it on a labor curve
Physical
Upon admission to the labor and delivery unit, determine
and document clinical findings. Clinical pelvimetry, which is best performed at the first prenatal care visit, is important in order to assess the pelvic type (e.g. android, gynecoid, platypelloid, anthropoid). Evaluate the position of the fetal head in early labor because caput and moulding complicate correct assessment as labor progresses. Establish and document an estimated fetal weight. Monitor fetal heart rate and uterine contraction patterns to assess fetal well-being and adequacy of labor. Perform a cervical examination to determine whether the patient is in the latent or active phase of labor. Addressing these issues allows for an assessment of the current phase of labor and anticipation of whether abnormal labor from any of the 3 P' s may be encountered.
Treatment
Medical care
Gabbe and colleagues state the following
For those in the latent phase, the treatment of choice is rest for several hours. During this interval, uterine activity, fetal status, and cervical effacement must be evaluated to determine if progress to the active phase has occurred. Approximately 85% of patients so treated progress to the active phase Approximately 10% will cease to have contractions, and the diagnosis of false labor may be made. For the approximately 5% of patients in whom therapeutic rest fails and in patients for whom expeditious delivery is indicated, oxytocin infusion may be used In cases of dysfunctional labor resulting from functional dystocia or an abnormal uterine contractility pattern and in which oxytocin implementation has not improved the outcome, a beta-blocker may be considered. Low-dose administration of intravenous propranolol in abnormal labor augmented with oxytocin reduced the need for cesarean delivery, particularly among patients with inadequate uterine contractility Anecdotal reports have stated that simply repositioning the patient frequently relieves a seemingly obstructed labor. Medication: A protocol called active management of labor can be applied to nulliparous women with singleton cephalic presentations at term. This method involves the use of high-dose oxytocin, with a starting rate of 6 mU/min and increasing by 6 mU/min every 15 min to a maximum of 40 mU/min. The goal is no more than 7 uterine contractions per 15 min. Under this protocol, cesarean delivery is performed if vaginal delivery has not occurred or is not imminent 12 hours after admission or for fetal compromise. Dinoprostone and misoprostol are prostaglandin analogs used to stimulate cervical dilation and uterine contractions; they are pharmacologic alternatives to using laminaria or placing a Foley bulb in the cervix. Using prostaglandin analogs with a scarred uterus (eg, from prior cesarean or myomectomy) for labor induction is absolutely contraindicated due to the significant risk for uterine rupture treatment for dystocia in spontaneous labor revealed that a single 1-mg dose of PgE2 vaginal gel Oxytocin (pintocin): Has a half-life of 3-5 min, and reaches steady state in approximately 40 min Common protocol: Start infusion at 1-2 mU/min IV and increase by 1-2 mU/min q30 min; continue until adequate contractions (>200 MVUs/10 min) achieved or (at some institutions) maximum rate of 20 mU/min achieved Beta-adrenergic blocking agents: Another option for abnormal labor secondary to inadequate uterine contractility is a beta-blocker propranolol: 2 mg IV; repeat one time only in 1 h if no progress observed
Surgical Care
Amniotomy is often used and has become an accepted
practice once the patient has reached the active phase of labor, although it has not been shown to result in shorter labor. This practice is not recommended in the latent phase of labor because it may only serve to increase the risk of intrauterine infection or cord prolapse If one of the arrest or protraction disorders is identified and fails to respond to conservative measures, or if the fetal heart pattern is nonreassuring, expedient delivery is justified; this includes operative vaginal delivery (if appropriate) or cesarean delivery as indicated.
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