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_History of DNA_Scientists

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21 views2 pages

_History of DNA_Scientists

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apsarasalami
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© © All Rights Reserved
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Date Name Discovery Importance to DNA

1869 Miescher -"nuclein" in the Discovered DNA


nuclei of human
white blood cells

1908 Thomas Hunt -working with chromosomal theory


Morgan Drosophila(fruit flies) of inheritance
-genes are on
chromosomes

1928 Griffith -cure for pneumonia Developed the ability


-Transforming factor to transform bacteria.
Led to the discovery
that DNA acts as the
carrier of genetic
information.

1944 Avery, MacLeod, -purified both DNA Showed that DNA


McCarty & proteins from (not proteins) can
Streptococcus transform the
pneumonia bacteria properties of cells,
clarifying the
chemical nature of
genes.

1949 Erwin Chargaff -Found that in any Found the


double-stranded relationship of base
DNA, guanine units pairs in DNA and
= cytosine units and found that DNA
adenine units = varies by species.
thymine units, and
that the composition
of DNA varies
between species.

1952 Hershey and Chase -worked with Confirmed DNA is


bacteriophage “transforming factor”
(viruses that infect
bacteria)
-grew phage viruses
in 2 media,

1952 Rosaland Franklin -discovered the Added to the


density of DNA discussion of DNA’s
-found that the structure and its
molecule existed in a replication process..
helical conformation.
-DNA Replication

1953 Watson and Crick -Proposed the double Developed the first
helix model of DNA double helix model of
DNA. Helped to
explain certain
actions of DNA.

1958 Meselson and Stahl -found that DNA Discovered DNA’s


replicated semiconservative
semi-conservatively ability.

1965 Marshall Nirenberg -discovered the first Discovered building


"triplet” blocks of protein are
made by DNA.
Discovered functions
of DNA.

1977 Frederick Sanger -obtained a protein Since the protein had


sequence a sequence, he
-proved that proteins suggested that the
were ordered genes and DNA that
molecules and by make these proteins
analogy should have an order
or sequence as well.

1990 Human Genome -international Helps to map DNA


Project scientific research and promote
project replication and
-goal of determining understanding.
the base pairs that
make up human DNA

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