Techniques Ultrasound-Guided Percutaneous Nephrolithotomy: How We Do It
Techniques Ultrasound-Guided Percutaneous Nephrolithotomy: How We Do It
Darren Beiko, MD, MBA, FRCSC1; Hassan Razvi, MD, FRCSC2; Naeem Bhojani, MD,
FRCSC3; Jennifer Bjazevic, MD, FRCSC2; David B. Bayne, MD4; David T. Tzou, MD5;
Marshall L. Stoller, MD4; Thomas Chi, MD4
1
Department of Urology, Queen’s University, Kingston, ON, Canada; 2Division of Urology, Department of
Surgery, Western University, London, ON, Canada; 3Division of Urology, Université de Montréal,
Montreal, QC, Canada; 4Department of Urology, University of California at San Francisco, San Francisco,
CA, United States; 5Division of Urology, Department of Surgery, University of Arizona College of
Medicine, Tucson, AZ, United States
Cite as: Can Urol Assoc J 2019 September 27; Epub ahead of print.
http://dx.doi.org/10.5489/cuaj.6076
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Abstract
Introduction
In Canada, percutaneous nephrolithotomy (PCNL) is performed almost exclusively using
fluoroscopy as the image-guiding modality of choice.1,2 While a long-established
standard for imaging guidance, this technique can be challenging to learn,3 limiting the
number of urologists who perform PCNL regularly as part of their clinical practice.4 To
the best of our knowledge, there are no publications originating from a Canadian
institution describing ultrasound-guided PCNL (US-PCNL). However, US-PCNL has
gained popularity in the United States,5 Asia,6 Europe,7 the Middle East,8 South
America,9 and Africa10 over the past several years. Some institutions use ultrasound in
combination with fluoroscopy as a strategy to reduce ionizing radiation exposure,11
whereas others use it to completely eliminate exposure to radiation during PCNL.12,13
Although several variations on access techniques exist among the many urologists
performing US-PCNL around the world,14 the main overarching goals of making renal
access easier for urologists to achieve and reduce ionizing radiation exposure for patients
and providers remain the same. When appropriate we offer our patients US-PCNL, and
herein we describe our technique and keys to successful implementation of this
procedure.
Method
Patient selection
When starting any new approach, it is important to carefully select patients to decrease
morbidity, optimize patient safety and ensure acceptable outcomes. We therefore
recommend selecting generally healthy patients when first adopting this technique.
Although obesity is not contraindicated, the extra tissue between the flank and kidney
pose a challenge during the steps requiring ultrasonography to optimize imaging.15 We
therefore recommend selecting non-obese patients initially and waiting to attempt US-
PCNL on obese patients until after mastering the technique. Usawachintachit et al
showed that successful US-PCNL was associated with the presence of hydronephrosis
and the absence of a staghorn calculus.12 In summary, the ideal initial candidate for US-
PCNL is a generally healthy, non-obese patient whose imaging demonstrates a non-
staghorn calculus and at least moderate hydronephrosis. When starting up a new US-
PCNL program, we recommend seeking out these characteristics in the first several US-
PCNL cases.
Procedural steps
in its entirety on the ultrasound monitor as it enters into the skin, crosses through the
subcutaneous, fascial, muscular, and perinephric layers through the kidney and into the
targeted calyx (Figure 4). While it is sometimes not possible to keep the needle in the
same plane and image as it is advanced into the target calyx, gently bouncing the needle
provides visual feedback to its location so that minor adjustments can be made. By
maintaining the longitudinal view and fanning the ultrasound probe back and forth to
identify the location of the needle relative to the targeted calyx, the needle can be re-
directed into the correct plane relative to the calyx of interest. Once in the collecting
system, removal of the needle stylet facilitates visualizing efflux of urine through the
needle or aspiration of urine confirms proper positioning of needle tip in the collecting
system. Our approach is to generally control the needle freehand without a needle guide
in order to preserve maximal flexibility in terms of angle of entry into the kidney. A
needle guide can, however, be attached to the ultrasound probe. Use of a needle guide
decreases the skill needed to keep the needle in the imaging view, and can therefore
facilitate easier renal access, particularly early in the surgeon’s learning curve.
system. Most balloon tips are slightly echogenic compared to the wire and the goal is to
visualize the tip as it advances into the collecting system to verify accurate placement.
Jiggling of the guidewire can aid in ensuring proper positioning of the balloon tip, which
is ideally within the entry calyx in most cases. Dilation of the balloon is then performed
to create the working tract (Figure 7).
Step 8: Nephrostogram
Contrast-enhanced ultrasound nephrostogram18 is performed using a low dose ultrasound
contrast agent solution. We inject 1.5 mL of Optison™ (GE Healthcare) through the
nephrostomy tube, immediately followed by a 5 mL injection of 0.9% NaCl flush, to
assess of patency of ureteropelvic junction and ureter.
Discussion
Since the inception of PCNL in the 1970’s,19 fluoroscopy has been the most commonly
used imaging modality used to guide the surgical steps, as reflected by 86.3% of PCNL
cases being performed with fluoroscopy guidance in the CROES Global PCNL study.20
CUAJ – Techniques in Urology Beiko et al
Techniques: Ultrasound-guided PCNL
urologists are much more familiar with performing and interpreting retrograde
pyelography and antegrade nephrostography compared to renal ultrasound. Additionally,
in 2019 ultrasound still lacks anatomic detail of the collecting system that is provided by
standard pyelography, particularly concerning the infundibulo-pelviceal anatomy and
angles. This can render certain steps of US-PCNL to be more challenging compared to F-
PCNL, including guidewire placement, tract dilation, sheath placement and placement of
a nephrostomy tube or ureteral stent. However, these disadvantages can be overcome as
experience is gained.
Potential disadvantages notwithstanding, ultrasound-guided PCNL has emerged,
however, as a reliable, effective and safe option. A systematic review on US-PCNL
versus F-PCNL was recently published, and it demonstrated that US-PCNL is as effective
as F-PCNL and is associated with lower complication rates.30 Certainly the known risks
of ionizing radiation have contributed to the trend toward US-PCNL, but as outlined in
Box 1 there are several added benefits of using ultrasonography to guide PCNL.
Conclusions
Ultrasound-guided PCNL has been widely shown to be safe and effective. This technique
is a “win-win” opportunity; patients as well as OR personnel will be exposed to less
ionizing radiation. Although learning US-PCNL may seem like a daunting task initially,
the literature has shown that this technique is relatively easy to learn and achievable by
any practicing urologist. We recommend it for urologists already performing PCNL who
want to increase the safety of PCNL and also for urologists not performing PCNL who
are interesting in learning PCNL.
CUAJ – Techniques in Urology Beiko et al
Techniques: Ultrasound-guided PCNL
References
B
CUAJ – Techniques in Urology Beiko et al
Techniques: Ultrasound-guided PCNL
Fig. 2. Acoustic shadows from stones (small arrows) and rib (large arrow) in longitudinal
plane.
CUAJ – Techniques in Urology Beiko et al
Techniques: Ultrasound-guided PCNL
Fig. 3. Needle enters skin 1 cm from caudal or cephalad end of ultrasound probe for (A)
lower and (B) upper pole puncture, respectively.
B
CUAJ – Techniques in Urology Beiko et al
Techniques: Ultrasound-guided PCNL
Fig. 4. Visualization of needle (arrow) in its entirely as it traverses all layers into kidney.
Fig. 7. Balloon dilation of lower pole tract (same case as Fig. 6).
CUAJ – Techniques in Urology Beiko et al
Techniques: Ultrasound-guided PCNL
Fig. 8. Percutaneous access sheath advanced until back end of balloon is seen through
external aspect of sheath.