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Umar Mock Test 1

The document consists of a mock test with multiple-choice questions covering topics in biology, particularly focusing on concepts related to ECG, hormone secretion, embryonic development, gene mutations, limb formation, and chemotaxis in sea urchins. Each question presents a scenario or statement with options that test the understanding of developmental biology principles. The questions require knowledge of specific genes, their functions, and the mechanisms involved in development and differentiation.

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deepak lourembam
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4 views

Umar Mock Test 1

The document consists of a mock test with multiple-choice questions covering topics in biology, particularly focusing on concepts related to ECG, hormone secretion, embryonic development, gene mutations, limb formation, and chemotaxis in sea urchins. Each question presents a scenario or statement with options that test the understanding of developmental biology principles. The questions require knowledge of specific genes, their functions, and the mechanisms involved in development and differentiation.

Uploaded by

deepak lourembam
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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Mock test 1

Part B
1. The QRS complex of an ECG indicates
a. Atrial depolarization
b. Ventricular depolarization
c. Ventricular repolarization
d. Atrial repolarization

2. The following graph represents the plasma concentration of two hormones A and B secreted
by pituitary during reproductive cycle
of a normal female. Which one of the
following combination in correct?
a. A is FSH while B is estrogen
b. A is estrogen while B is LH
c. A is LH while B is FSH
d. A is FSH while B is LH

3. If you transplanted embryo from the leg area to the back area, but they still developed into
leg structure, the original cells must have been
a. Determined
b. Determined, but not specified
c. Specified, but not determined
d. None of the above

4. The dorsalizing signal from the oocyte nucleus in drosophila development appears to be the
product of the
a. gurken gene
b. torpedo gene
c. toll gene
d. dorsal gene

5. The grafting of a second polarizing region into the anterior of the limb bud in chick results in:
a. Formation of the second bud at the site of the graft.
b. Formation of extra copies of the anterior-most digits, digit 2, is the only possible result.
c. Formation of extra copies of the posterior-most digits, digit 4, is the only possible result.
d. A new axis can be formed if the second polarizing region is large, and a second full set of
digits can form with mirror-image orientation to the normal set of digits.

6. Which gene mutation occured in the given picture of Drosophila?


a. Antp gene mutation
b. Ubx gene mutation
c. Lab gene mutation
d. Abd gene mutation
Part C
7. Limbs in amphibian are not from anywhere along the body axis but they are formed in a
discrete position of their embryo. Some statements are given regarding limbs formation.
A. Retinoic acid is critical for the initiation of limb bud outgrowth
B. Zone of polarizing activity (ZPA) which is necessary for the proper anterior-posterior axis
patterning are located at ectodermal region.
C. When apical ectodermal ridge (AER) was removed at any time of development, further
growth of mesenchyme cells ceased and no more distal structures in limb formation.
D. When limb mesenchyme was replaced by a non-limb mesenchyme beneath the AER, still
there will be limb development.

Which of the following statement is correct?

a. A only
b. B only
c. A and C
d. B and D

8. Some statements are given related to homeotic genes expression in Drosophila:


A. Antennapedia gene mutations results in the formation legs in the place of antennas.
B. Ultrabithorax (ubx) gene maintains the identity of the 2nd thoracic segment.
C. Mutation in ubx gene give rise to pair haltere instead of winds in both 2 nd and 3rd
thoracic segments.
D. Main function of Abdominal (Abd) gene is to repress limb formation in the abdominal
area.
Which of the following is INCORRECT?
a. A and B
b. B and C
c. C and D
d. A and D

9. Some statements regarding sperm chemotaxis in sea urchin are given.


A. The binding of resact protein to its receptor, guanylyl cyclase (GC), activates cGMP
synthesis.
B. Rise in cGMP possibly activates the Na+ selective ion channels resulting in
hyperpolarization of the membrane.
C. The flagellar asymmetry and turns of sperm is initiated by the entry of Ca2+ through
voltage-activated Ca2+ channels.
D. The cGMP signal is terminated by the hydrolysis of cGMP through phosphodiesterase
(PDE) activity and inactivation of GC.

Which of the following statements are true regarding sperm chemotaxis?


a. A, B, D
b. A, C, D
c. B, C, D
d. A, B, C

10. When the prospective neurons from an early gastrula of a frog were transplanted into the
prospective epidermal region, the donor cell differentiate into epidermis. However, when
the similar experiment was done with the late gastrula, the prospective neurons developed
into neuron only. These observations can be explained by:
A. The early gastrula shows conditional development, whereas the late gastrula shows
autonomous development.
B. Early gastrula shows autonomous development whereas late gastrula shows
conditional.
C. Prospective neuron from early gastrula are only specified whereas those from late
gastrula were determined.
D. Prospective neuron from the early gastrula are determined whereas those from late
gastrula were specified.
Which of the above statements are correct?
a. A and B
b. A and D
c. A and C
d. B and D

11. The limb buds have to be specified as being those of either the forelimb or the hindlimb. If
FGF secreting beads were used to induce an ectopic limb between the chick hindlimb and
forelimb buds, the type of limb produced was determined by the Tbx protein expressed.
Some statements are given for this type of specification.
A. Those buds induced by placing FGF beads close to the hindlimb expressed Tbx5 and
became hindlimbs (legs).
B. Those buds induced close to the forelimb expressed Tbx5 and developed as forelimbs
(wings).
C. Those buds induced in the centre of the flank tissue expressed Tbx5 in the anterior
portion of the limb and Tbx4 in the posterior portion of the limb, developing chimeric
structures, with the anterior resembling a forelimb and the posterior resembling a
hindlimb.
D. There will be no such formation of chimeric structure when buds are induced in the
centre of the flank tissue.
Which of the following statement is/are correct?
a. A only
b. B only
c. B and C
d. B, C and D

12. Caenorhabditis elegans show both autonomous as well as conditional type of specifications.
Some of the genes has been identified which are believed to define these two types of
specification in the developmental procedure. Some of the statements are given below
regarding the above statement:
A. SKN -1 protein is a maternally expressed polypeptide that may control the fate of the
EMS blastomere and is able to generate pharyngeal mucles cells.
B. PAL -1 protein is required for the germ line fate by repressing the establishment of
somatic cell fate and preserves the totipotency of the germ call lineage.
C. The P2 cell produces the C elegans homologue of a Wnt protein, MOM – 5 peptides and
received by MOM – 2 protein homologue with Frizzled and ultimately downregulated
POP-1 gene in the EMS daughter destines to become the Endoderm cell.
D. GLP – 1 protein (Notch protein family) is expressed in ABp cells and interact with APX – 1
(Delta like protein) from P2 cells which makes ABp cell fate different from Aba cell fate.
Which of the combination are INCORRECT?
a. A and B
b. B and C
c. C and D
d. A and D

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