Deep Science Publishing

https://doi.org/10.70593/978-81-981271-4-3_8

Chapter 8

From challenges to implementation and

acceptance: Addressing key barriers in
artificial intelligence, machine learning, and
deep learning
Nitin Liladhar Rane 1, Suraj Kumar Mallick 2, Ömer Kaya 3, Jayesh Rane 4
1
Vivekanand Education Society’s College of Architecture (VESCOA), Mumbai 400074, India
2
Shaheed Bhagat Singh College, University of Delhi, New Delhi 110017, India
3
Engineering and Architecture Faculty, Erzurum Technical University, Erzurum 25050, Turkey
4
Pillai HOC College of Engineering and Technology, Rasayani, India
1 [email protected]

Abstract: Machine learning (ML) and deep learning (DL) have transformed different industries
by facilitating sophisticated data analysis, predictive modeling, and autonomous decision-making.
Despite the ability to greatly change things, there are many obstacles preventing their widespread
use and impact. A major obstacle is the challenge of data quality and quantity; ML and DL models
need large amounts of high-quality, labeled data, which can be hard and expensive to acquire.
Moreover, the innate intricacy of these models frequently results in a dearth of clarity and visibility,
posing difficulties in comprehending and having faith in their decision-making procedures. This
has caused worries about ethical ramifications and favoritism, since models may unknowingly
continue current biases found in the data used for training. Moreover, the fast rate of technological
progress leads to a constantly changing environment, requiring practitioners and organizations to
continuously learn and adapt. Security and privacy concerns are significant challenges due to the
susceptibility of ML and DL models to attacks and breaches, jeopardizing the security of private
data. Additionally, incorporating ML and DL into current systems and processes presents
challenges such as requiring unique knowledge and ensuring that technological solutions align
with business goals.

Keywords: Artificial intelligence, Deep learning, Machine learning, Challenges, Data Quality,
Data Privacy and Security.

Citation: Rane, N. L., Mallick, S. K., Kaya, O., & Rane, J. (2024). From challenges to
implementation and acceptance: Addressing key barriers in artificial intelligence, machine
learning, and deep learning. In Applied Machine Learning and Deep Learning: Architectures
and Techniques (pp. 153-166). Deep Science Publishing. https://doi.org/10.70593/978-81-
981271-4-3_8

https://deepscienceresearch.com 153
8.1 Introduction

Machine learning (ML) and deep learning (DL) have transformed many industries with
their ability to offer advanced data analysis, pattern recognition, and predictive features
(Thakkar & Lohiya, 2021; Kocher & Kumar, 2021; Wani et al., 2022). These technologies
have enabled substantial progress in fields like healthcare, finance, autonomous systems,
and natural language processing (Rani et al., 2022; Bhatt et al., 2021; Goshisht, 2024).
Although they are widely utilized and achieve success, ML and DL face obstacles that
prevent them from reaching their maximum capabilities. These challenges vary from
technical problems like model interpretability and data quality to ethical issues such as bias
and privacy concerns (Kocher & Kumar, 2021; Wani et al., 2022; Rani et al., 2022;
Mohammed & Kora, 2023; Nasir & Sassani, 2021). A major obstacle in ML and DL is
understanding complex models, particularly deep neural networks (Wani et al., 2022;
Shamshirband et al., 2021; Al-amri et al., 2021; Bhushan et al., 2023). As these models
advance, it becomes harder to comprehend and clarify how they make decisions (Wani et
al., 2022; Jdey et al., 2022; Alzubaidi et al., 2021; Alafif et al., 2021). This lack of
transparency can pose a significant challenge in critical applications where being open and
responsible is crucial. Furthermore, how well ML and DL models perform greatly relies
on the quality and quantity of data (Kocher & Kumar, 2021; Talaei Khoei et al., 2023;
Chiche & Yitagesu, 2022; Fikri et al., 2021). Inaccurate predictions and unreliable
outcomes may result from poor data quality, including incomplete, noisy, or biased
datasets. Furthermore, the computational demands for training expansive DL models can
be excessively high, requiring a substantial investment in hardware and energy usage.
Table 8.1 summarizes the various application areas of machine learning and deep learning,
the methods used in these areas, success metrics, and challenges faced. A wide range of
applications such as image recognition, natural language processing, anomaly detection,
recommendation systems, voice recognition, robotic control, financial forecasting and
health analytic have been evaluated with their own specific methods and metrics
(L’heureux et al., 2017; Kaluarachchi et al., 2021; Khademi et al., 2023). In addition, the
unique challenges of each application area are stated and ways to overcome these
challenges are discussed. This table provides a comprehensive perspective to understand
how machine learning and deep learning techniques are used in industry and what
challenges they face.

Table 8.1 Application Areas, Success Metrics and Challenges of ML and DL

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 Success
Application area Methods Challenges Explanation
Metrics
Cost of data
Accuracy, F1 labeling, High Medical image
Image CNN, Transfer
Score, Kappa processing analysis, face
Recognition Learning
Statistics power detection
requirement
Accuracy, Language
RNN, Text classification,
NLP Bleu Score, diversity,
Transformers machine translation
Perplexity ambiguity
Accuracy, F1
Anomaly Autoencoders, False positive Fraud detection,
Score, ROC-
Detection Isolation Forest rate network security
AUC
Collaborative RMSE,
Recommendation Movie and product
Filtering, Matrix MAE, Scalability
Systems recommendations
Factorization Precision
Hidden Markov
Accuracy, Noise resistance,
Voice Models (HMM), Speech recognition,
Word Error Variety of
Recognition Deep Neural voice assistants
Rate (WER) accents
Networks (DNN)
Real-time
Reinforcement Average Autonomous
computing,
Robotic Control Learning, Q- Reward, vehicles, robotic
Security and
Learning Success Rate arms
reliability
Market
Financial Time Series MAPE, Stock forecast, risk
fluctuations,
Prediction Analysis, LSTM RMSE, R^2 analysis
Data biases
Accuracy,
Random Forest, Data privacy, Disease diagnosis,
AUC,
Health Analytic Support Vector Data patient results
Sensitivity,
Machines (SVM) heterogeneity analysis
Specificity

In addition to technical challenges, ML and DL also encounter significant ethical and

societal issues (Kocher & Kumar, 2021; Wani et al., 2022; Silva & Najafirad, 2020;
Asharf et al., 2020; Ahmed et al., 2023). Bias within algorithms and data sets can continue
and exacerbate current disparities, resulting in unjust and prejudicial results (Hong et al.,
2020; Fregoso-Aparicio et al., 2021; Dinsdale et al., 2022). Another crucial issue to
address in ML applications is maintaining privacy and security, as the utilization of
personal and sensitive information raises concerns regarding the protection of data and
user agreement (Goshisht, 2024; Abdar et al., 2021; Yuan et al., 2020; Sapoval et al.,

155
2022). Moreover, the fast progress of ML and DL technologies has exceeded the creation
of regulatory frameworks, causing a lack in governance and ethical standards (Wani et
al., 2022; Mishra et al., 2021; Yuan & Wu, 2021; Li et al., 2021). In this study, we carry
out an extensive review of literature to pinpoint and examine the main obstacles in ML
and DL. We have made three significant additions to the current knowledge base:

⚫ We conduct a thorough analysis of the technical obstacles in ML and DL,

emphasizing model interpretability, data quality, and computational requirements.
⚫ We examine the ethical and social consequences of ML and DL, focusing on
concerns regarding bias, privacy, and regulations.
⚫ We suggest possible solutions and directions for future research to tackle these
challenges, with the goal of improving the efficiency, equity, and transparency of
ML and DL applications.

8.2 Methodology

Firstly, an in-depth search of pertinent academic databases was carried out, such as IEEE
Xplore, ACM Digital Library, Google Scholar, and ScienceDirect. The literature search
included terms like "barriers in machine learning," "difficulties in deep learning,"
"limitations of ML," "issues in DL," and "obstacles in artificial intelligence." The
exploration concentrated on peer-reviewed articles, conference papers, and respected
technical reports released in the past ten years to ensure the incorporation of the latest
developments and conversations. Furthermore, strict criteria for inclusion and exclusion
were used to sift through the search results. Research will be considered if it focuses on
difficulties with machine learning and deep learning, presents either data-driven findings
or theoretical insights, and is written in the English language. Research that only looks
into the uses of something, without addressing the difficulties, sources that haven't been
peer-reviewed, and materials published before 2014 were not considered in order to
uphold the quality and importance of the analysis. Next, the chosen articles underwent an
in-depth content analysis. This required extracting important details on the different
obstacles found, classifying them, and combining the results into cohesive themes. The
difficulties were grouped into four main areas: technical, methodological, ethical, and
practical. Technical obstacles include problems such as over-fitting, computational
complexity, and data quality. Challenges in methodology involve understanding models,
requiring extensive data, and ensuring algorithm reliability. Ethical dilemmas focus on
issues like prejudice, equity, and openness in machine learning and deep learning models,
whereas practical dilemmas involve implementing, scaling, and up-keeping these
technologies in practical situations.

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8.3 Results and discussions

Challenges and potential solutions in machine learning and deep learning

ML and DL have transformed many areas by allowing systems to learn from data and
make decisions with slight human involvement (Kocher & Kumar, 2021; Wani et al.,
2022; Rani et al., 2022; Bhatt et al., 2021; Mohammed & Kora, 2023; Nasir & Sassani,
2021; Kaluarachchi et al., 2021; Yeole, 2024; Xu et al., 2021; Taye, 2023). In spite of
their notable progress and extensive use, these technologies encounter various inherent
difficulties that may impede their effectiveness and acceptance (Goshisht, 2024;
Mohammed & Kora, 2023; Nasir & Sassani, 2021; Shamshirband et al., 2021;
Rezaeianjouybari & Shang, 2020; Shafay et al., 2023; Liu et al., 2020; Dar et al., 2022).

Fig 8.1 Challenges in DL and ML

Fig 8.1 highlights different learning methods, such as deep learning, online learning, local
learning, transfer learning, lifelong learning, and community learning, and the challenges
each faces. Each learning paradigm faces unique challenges. While dealing with problems
such as deep learning, feature engineering, nonlinearity and data heterogeneity; online
learning and local learning face similar challenges such as processing performance, the
curse of modularity, class imbalance, and data locality. While transfer learning combats
class imbalance and data heterogeneity; lifelong learning faces additional challenges such
as data availability and real-time processing. Ensemble learning, on the other hand,
involves challenges such as processing performance, the curse of modularity, and concept
drift.

Data Quality and Quantity

One of the biggest problems in ML and DL is the lack of diverse and high-quality datasets.
This models demand extensive amounts of labeled data for efficient training. Obtaining
this data can often be both costly and require a significant amount of time. Furthermore,

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the importance of data quality cannot be overstated, as low-quality data can result in
imprecise models and untrustworthy results. Challenges like incomplete data,
interference, and prejudices within datasets can greatly affect the effectiveness of ML
models. Ensuring a variety of data is important as models trained on similar data may
struggle to perform well in new or real-life situations. Various methods can be utilized to
address the problem of both the quality and quantity of data. Methods like creating
artificial data and transferring knowledge from one dataset to another can boost the variety
and size of datasets. Furthermore, tapping into crowdsourcing and utilizing public datasets
can offer a greater amount of labeled data. Developing strong data preprocessing pipelines
to cleanse and standardize data can enhance its quality. Active learning involves models
asking human annotators for labels on the most informative samples in an iterative
process, aiding in the efficient collection of high-quality labeled data.

Data Privacy and Security

Ensuring data privacy and security has become a critical concern due to the rising
utilization of ML and DL in sensitive areas such as healthcare, finance, and personal data.
It is difficult to protect user data from breaches and unauthorized access, particularly due
to the increase in sophisticated cyber-attacks. Furthermore, there is ongoing exploration
of methods such as differential privacy and federated learning to train models while
protecting individual privacy, although these approaches need additional development
before they can be fully effective and widely accepted. In order to safeguard data privacy
and security, methods such as differential privacy can be utilized to prevent individual
data points from being inferred from aggregated data. Federated learning enables models
to be trained on various devices or servers that store local data samples, without sharing
them, thus safeguarding privacy. Advanced cryptographic techniques like secure multi-
party computation and homomorphic encryption allow for computations to be performed
on encrypted data without requiring decryption, maintaining data privacy during the entire
process.

Model Interpretability and Explainability

DL models, especially neural networks, are frequently referred to as "black boxes"

because of their intricate and opaque nature. The absence of interpretability presents
major obstacles, particularly in industries like healthcare, legal, and financial services
where comprehending the decision-making process is vital. Creating ways to improve the
interpretability and explainability of these models is crucial for establishing trust and
guaranteeing ethical implementation. Approaches such as Explainable AI (XAI) are
designed to offer understanding on how models reach decisions, however striking a
balance between model intricacy and interpretability is still a persistent obstacle.

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Enhancing the interpretability and explainability of models can be accomplished by
creating techniques for Explainable Artificial Intelligence (XAI). Approaches like SHAP,
LIME, and attention mechanisms in neural networks offer understanding into how models
make decisions. In addition, creating simpler models that are naturally easier to
understand, or incorporating a mix of interpretable and complex components in hybrid
models, can assist in achieving a balance between performance and explainability.

Fig. 8.2 Sankey diagram on challenges and potential solutions in ML and DL

Computational and Resource Constraints

Training DL models necessitates significant computational resources, such as strong

GPUs and vast memory capacity. The significant expense of computation may pose a
barrier for numerous organizations, especially those operating on a tight budget.
Moreover, the significant energy usage linked to the training of large models is causing
worries about its environmental effects. Efficient algorithms and hardware accelerators
are being created to tackle these challenges, yet the quick increase in model complexity
is still surpassing these advancements. In order to deal with limitations in computing
power and resources, methods like pruning, quantization, and knowledge distillation can
be used to decrease the size and complexity of models while still maintaining high
performance. Leveraging specialized hardware accelerators such as GPUs, TPUs, and
custom AI chips can improve computational efficiency. Moreover, cloud-based
alternatives and distributed computing platforms such as Apache Spark and TensorFlow
can assist in expanding computational resources as needed.

Generalization and Over-fitting

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Generalization is when an ML model can effectively handle data it has not seen before.
Over-fitting happens when a model becomes too focused on the training data, including
noise and outliers, leading to decreased accuracy on test data. Finding the perfect
equilibrium between inadequate fitting and excessive fitting is an ongoing struggle in the
fields of ML and DL. Methods such as regularization, cross-validation, and dropout are
frequently utilized to address over-fitting, though they are not infallible and often
necessitate precise adjustments. Several techniques can be utilized to enhance
generalization and reduce over-fitting. Methods like L1 and L2 regularization, dropout,
and early stopping are useful in avoiding over-fitting. Cross-validation techniques can be
employed to guarantee that models perform effectively with unseen data. Data
augmentation, the process of generating additional training examples by modifying
current data, can improve generalization as well. Furthermore, ensemble learning
techniques involve training multiple models and aggregating their predictions, which can
result in more resilient and versatile results.

Ethical and Bias Concerns

ML and DL models can be biased due to biased training data, model design, and
deployment processes. These prejudices can result in unjust and discriminatory results,
especially in situations involving people. Ensuring equity and ethical conduct in ML
models is a complicated process that involves thorough testing, validation, and
monitoring. It is vital to address these concerns in order to avoid harm and guarantee that
ML systems are fair and righteous. Dealing with ethical and bias issues necessitates a
comprehensive strategy. It is essential to include diversity in training datasets and make a
conscious effort to recognize and address biases during data collection and pre-
processing. Incorporating algorithms that prioritize fairness and integrating fairness
limitations in the model training process can assist in mitigating biased results. It is crucial
to constantly monitor and audit models to ensure fairness and reduce bias, as well as to
be transparent when reporting the performance of models for various demographic
groups. Interacting with ethicists and various stakeholder groups can offer insightful
perspectives and direction on the ethical deployment of AI.

Robustness and Adversarial Attacks

ML models, especially DL models, can be easily fooled by adversarial attacks using

specially crafted inputs to make inaccurate predictions. These incidents reveal the
vulnerability of ML systems and present serious security threats, particularly in vital areas
such as autonomous driving and cybersecurity. Research in creating strong models that
can resist attacks is ongoing, using methods such as adversarial training and defensive
distillation. Nevertheless, developing models that are resilient and precise continues to be

160
a considerable obstacle. Adversarial training can be utilized to boost resilience and protect
against adversarial attacks by training models with adversarial examples. Defensive
distillation and gradient masking are additional strategies employed to reduce the
vulnerability of models to adversarial inputs. Consistently updating models and
integrating detection mechanisms to recognize and counter adversarial attacks can
enhance resilience. Ongoing studies in durable structures and algorithms that possess
natural resistance to adversarial manipulations are showing potential.

Scalability and Real-Time Processing

As data volume rapidly increases, scalability becomes increasingly important for ML and
DL systems. Dealing with big datasets and efficiently training models is a challenging
task. Moreover, numerous use cases, like real-time analytic and autonomous systems,
necessitate quick processing and decision-making skills. It is crucial for the practical
deployment of ML models to guarantee they can scale efficiently and function in real-
time settings. Approaches such as distributed computing and edge computing are being
researched to tackle these issues, yet achieving smooth integration remains complicated.
Distributed computing and parallel processing frameworks can help solve problems
related to scalability and real-time processing. Methods such as model parallelism and
data parallelism enable the distribution of work among various processors. Edge
computing, which means handling data close to where it is created (such as IoT devices),
can decrease delays and improve the ability to process data in real-time. Enhancing
scalability can be improved by implementing efficient algorithms and optimizing code to
take advantage of hardware accelerations.

Integration and Deployment

Incorporating ML and DL models into current systems and workflows may present
difficulties. Deployment includes not only integrating technically, but also involves
thinking about model maintenance, updates, and monitoring. Continuous evaluation and
retraining are necessary to maintain the accuracy and reliability of models as new data is
introduced. Furthermore, the deployment procedure needs to consider the scalability of
the infrastructure, compatibility with other systems, and adherence to regulatory
standards. Using containerization technologies like Docker and Kubernetes can aid in the
smooth integration and deployment of ML and DL models, allowing for the management
and scaling of applications in various environments. CI/CD pipelines automate the
deployment process, guaranteeing that models are consistently updated and cared for.
Tools for monitoring models are capable of monitoring performance, detecting drifts, and
sending alerts to ensure prompt retraining and adjustments. Facilitating smoother

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integration can be achieved by ensuring that standardized APIs and data formats are used
to ensure interoperability with existing systems.

Continuous Learning and Adaptation

ML models must constantly adjust to changing conditions and new data in order to keep
up with the dynamic nature of real-world environments. Conventional static models could
easily become obsolete, resulting in a decline in performance. Creating systems that can
constantly learn and adjust, also known as lifelong learning or online learning, is a
difficult yet essential progression for more robust and efficient ML applications. It is
essential for these systems to effectively integrate new information while also preserving
knowledge obtained in the past. In order to promote ongoing learning and adjustment,
incremental learning methods can be utilized, enabling models to be updated with fresh
data without needing to start over with training. Online learning algorithms are able to
adjust to fresh data instantly, which makes them appropriate for scenarios that are
constantly changing. Ensuring that models stay relevant and accurate can be achieved by
incorporating feedback loops that use user interactions to inform ongoing model updates.
Methods such as transfer learning can be used to utilize knowledge from tasks that have
been learned before when facing new tasks that are related.

Cost and Accessibility

The expense of creating and implementing ML and DL solutions may be too high for
small and medium-sized businesses (SMEs). The significant expense of computational
resources, data acquisition, and skilled staff acts as barriers to entry and restricts the
widespread accessibility of these technologies. Decreasing these expenses is important to
make ML and DL accessible to more people. This can be achieved through creating better
algorithms and providing open-source resources and pre-trained models. Utilizing open-
source frameworks and pre-trained models can cut down on costs and improve access to
ML and DL technologies, resulting in faster deployment processes. Cloud-based artificial
intelligence services provide flexible options that can be utilized on a pay-as-you-use
model, allowing smaller businesses to affordably access them. Investing in education and
training initiatives for ML and DL can make these technologies accessible to more people.
Collaborative platforms and shared resources can also reduce obstacles to getting started.

The Sankey diagram (Fig. 8.2) visually depicts the different obstacles encountered in ML
and DL, as well as possible ways to tackle these challenges. The main obstacles consist
of problems with data quality, scarcity of training data, worries about data privacy, bias
in algorithms, high computational expenses, lack of transparency, compatibility with
current systems, difficulties with scaling, and ethical issues. Each of these obstacles is
linked to one or more solutions that seek to alleviate the related issues. Data augmentation

162
and transfer learning can help overcome data quality problems and lack of training data
by enriching the existing data and boosting model performance. Federated learning
addresses data privacy issues by enabling models to be trained on multiple devices
without the need to share sensitive data. Regularization techniques help reduce algorithm
bias by enhancing both fairness and accuracy. Using cloud computing resources helps to
lower computational expenses by offering scalable and cost-efficient computational
power. The issue of lacking explainability is tackled with the creation of understandable
AI techniques that increase transparency in models' decision-making processes. Utilizing
cloud and edge computing can help alleviate integration with existing systems and
scalability issues, ensuring efficient processing and seamless integration at the data
source. Managing ethical concerns involves implementing ethical guidelines to promote
the responsible utilization of AI technologies. Moreover, methods for compressing
models aid in decreasing computational burden and enhancing model efficiency.

8.4 Conclusions

ML and DL have been seen remarkable progressions, but it still faces substantial hurdles
hindering its full potential. A major hurdle is the requirement for extensive amounts of
labeled data to properly train models. Although unsupervised and semi-supervised
learning methods are becoming more popular, the need for high-quality labeled data
continues to be a limiting factor. Furthermore, the concern regarding data privacy and
security has grown more evident, especially as personal and organizational data utilized
in training models becomes more sensitive. Approaches such as federated learning and
differential privacy are being developed to tackle these issues, although they are still in
the early stages of being put into practice. Interpreting and explaining models is crucial,
particularly in industries like healthcare and finance, that require transparent and justified
decisions based on ML and DL models. Explainable AI (XAI) is advancing, yet finding a
middle ground between model complexity and interpretability continues to be a challenge.
Moreover, the requirements for computational power and energy consumption for training
extensive DL models are significant. Explorations of hardware innovations like improved
GPUs and TPUs, along with progress in quantum computing, aim to address these
problems, but practical, widely applicable solutions are still in progress.

The ethical challenges posed by AI, such as bias in both data and algorithms, are a major
concern. Maintaining fairness and reducing biases necessitates ongoing work in data
selection and model development phases. Dealing with these difficulties requires a cross-
disciplinary strategy, merging technological progress with strong regulatory structures
and moral principles. Advancing in the field requires overcoming these obstacles to
ensure the long-term and fair use of ML and DL technologies.

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References
Abdar, M., Pourpanah, F., Hussain, S., Rezazadegan, D., Liu, L., Ghavamzadeh, M., ... &
Nahavandi, S. (2021). A review of uncertainty quantification in deep learning: Techniques,
applications and challenges. Information fusion, 76, 243-297.
Ahmed, S. F., Alam, M. S. B., Hassan, M., Rozbu, M. R., Ishtiak, T., Rafa, N., ... & Gandomi, A.
H. (2023). Deep learning modelling techniques: current progress, applications, advantages, and
challenges. Artificial Intelligence Review, 56(11), 13521-13617.
Alafif, T., Tehame, A. M., Bajaba, S., Barnawi, A., & Zia, S. (2021). Machine and deep learning
towards COVID-19 diagnosis and treatment: survey, challenges, and future directions.
International journal of environmental research and public health, 18(3), 1117.
Al-amri, R., Murugesan, R. K., Man, M., Abdulateef, A. F., Al-Sharafi, M. A., & Alkahtani, A. A.
(2021). A review of machine learning and deep learning techniques for anomaly detection in
IoT data. Applied Sciences, 11(12), 5320.
Alzubaidi, L., Zhang, J., Humaidi, A. J., Al-Dujaili, A., Duan, Y., Al-Shamma, O., ... & Farhan,
L. (2021). Review of deep learning: concepts, CNN architectures, challenges, applications,
future directions. Journal of big Data, 8, 1-74.
Asharf, J., Moustafa, N., Khurshid, H., Debie, E., Haider, W., & Wahab, A. (2020). A review of
intrusion detection systems using machine and deep learning in internet of things: Challenges,
solutions and future directions. Electronics, 9(7), 1177.
Bhatt, C., Kumar, I., Vijayakumar, V., Singh, K. U., & Kumar, A. (2021). The state of the art of
deep learning models in medical science and their challenges. Multimedia Systems, 27(4), 599-
613.
Bhushan, M., Pandit, A., & Garg, A. (2023). Machine learning and deep learning techniques for
the analysis of heart disease: a systematic literature review, open challenges and future
directions. Artificial Intelligence Review, 56(12), 14035-14086.
Chiche, A., & Yitagesu, B. (2022). Part of speech tagging: a systematic review of deep learning
and machine learning approaches. Journal of Big Data, 9(1), 10.
Dar, R. A., Rasool, M., & Assad, A. (2022). Breast cancer detection using deep learning: Datasets,
methods, and challenges ahead. Computers in biology and medicine, 149, 106073.
Dinsdale, N. K., Bluemke, E., Sundaresan, V., Jenkinson, M., Smith, S. M., & Namburete, A. I.
(2022). Challenges for machine learning in clinical translation of big data imaging studies.
Neuron, 110(23), 3866-3881.
Fikri, M. A., Santosa, P. I., & Wibirama, S. (2021). A review on opportunities and challenges of
machine learning and deep learning for eye movements classification. In 2021 IEEE
International Biomedical Instrumentation and Technology Conference (IBITeC) (pp. 65-70).
IEEE.

164
Fregoso-Aparicio, L., Noguez, J., Montesinos, L., & García-García, J. A. (2021). Machine learning
and deep learning predictive models for type 2 diabetes: a systematic review. Diabetology &
metabolic syndrome, 13(1), 148.
Goshisht, M. K. (2024). Machine learning and deep learning in synthetic biology: Key
architectures, applications, and challenges. ACS omega, 9(9), 9921-9945.
Hong, S., Zhou, Y., Shang, J., Xiao, C., & Sun, J. (2020). Opportunities and challenges of deep
learning methods for electrocardiogram data: A systematic review. Computers in biology and
medicine, 122, 103801.
Jdey, I., Hcini, G., & Ltifi, H. (2022). Deep learning and machine learning for Malaria detection:
Overview, challenges and future directions. arXiv preprint arXiv:2209.13292.
Kaluarachchi, T., Reis, A., & Nanayakkara, S. (2021). A review of recent deep learning approaches
in human-centered machine learning. Sensors, 21(7), 2514.
Kaluarachchi, T., Reis, A., & Nanayakkara, S. (2021). A review of recent deep learning approaches
in human-centered machine learning. Sensors, 21(7), 2514.
Khademi, Z., Ebrahimi, F., & Kordy, H. M. (2023). A review of critical challenges in MI-BCI:
From conventional to deep learning methods. Journal of Neuroscience Methods, 383, 109736.
Kocher, G., & Kumar, G. (2021). Machine learning and deep learning methods for intrusion
detection systems: recent developments and challenges. Soft Computing, 25(15), 9731-9763.
L’heureux, A., Grolinger, K., Elyamany, H. F., & Capretz, M. A. (2017). Machine learning with
big data: Challenges and approaches. Ieee Access, 5, 7776-7797.
Li, L., Li, X., Jiang, L., Su, X., & Chen, F. (2021). A review on deep learning techniques for cloud
detection methodologies and challenges. Signal, Image and Video Processing, 15(7), 1527-
1535.
Liu, F., Xue, S., Wu, J., Zhou, C., Hu, W., Paris, C., ... & Yu, P. S. (2020). Deep learning for
community detection: progress, challenges and opportunities. arXiv preprint
arXiv:2005.08225.
Mishra, R. K., Reddy, G. S., & Pathak, H. (2021). The understanding of deep learning: A
comprehensive review. Mathematical Problems in Engineering, 2021(1), 5548884.
Mohammed, A., & Kora, R. (2023). A comprehensive review on ensemble deep learning:
Opportunities and challenges. Journal of King Saud University-Computer and Information
Sciences, 35(2), 757-774.
Nasir, V., & Sassani, F. (2021). A review on deep learning in machining and tool monitoring:
Methods, opportunities, and challenges. The International Journal of Advanced Manufacturing
Technology, 115(9), 2683-2709.
Rani, P., Kotwal, S., Manhas, J., Sharma, V., & Sharma, S. (2022). Machine learning and deep
learning based computational approaches in automatic microorganisms image recognition:
methodologies, challenges, and developments. Archives of Computational Methods in
Engineering, 29(3), 1801-1837.
Rezaeianjouybari, B., & Shang, Y. (2020). Deep learning for prognostics and health management:
State of the art, challenges, and opportunities. Measurement, 163, 107929.

165
Sapoval, N., Aghazadeh, A., Nute, M. G., Antunes, D. A., Balaji, A., Baraniuk, R., ... & Treangen,
T. J. (2022). Current progress and open challenges for applying deep learning across the
biosciences. Nature Communications, 13(1), 1728.
Shafay, M., Ahmad, R. W., Salah, K., Yaqoob, I., Jayaraman, R., & Omar, M. (2023). Blockchain
for deep learning: review and open challenges. Cluster Computing, 26(1), 197-221.
Shamshirband, S., Fathi, M., Dehzangi, A., Chronopoulos, A. T., & Alinejad-Rokny, H. (2021). A
review on deep learning approaches in healthcare systems: Taxonomies, challenges, and open
issues. Journal of Biomedical Informatics, 113, 103627.
Silva, S. H., & Najafirad, P. (2020). Opportunities and challenges in deep learning adversarial
robustness: A survey. arXiv preprint arXiv:2007.00753.
Talaei Khoei, T., Ould Slimane, H., & Kaabouch, N. (2023). Deep learning: Systematic review,
models, challenges, and research directions. Neural Computing and Applications, 35(31),
23103-23124.
Taye, M. M. (2023). Understanding of machine learning with deep learning: architectures,
workflow, applications and future directions. Computers, 12(5), 91.
Thakkar, A., & Lohiya, R. (2021). A review on machine learning and deep learning perspectives
of IDS for IoT: recent updates, security issues, and challenges. Archives of Computational
Methods in Engineering, 28(4), 3211-3243.
Wani, J. A., Sharma, S., Muzamil, M., Ahmed, S., Sharma, S., & Singh, S. (2022). Machine
learning and deep learning based computational techniques in automatic agricultural diseases
detection: Methodologies, applications, and challenges. Archives of Computational methods in
Engineering, 29(1), 641-677.
Xu, Y., Zhou, Y., Sekula, P., & Ding, L. (2021). Machine learning in construction: From shallow
to deep learning. Developments in the built environment, 6, 100045.
Yeole, A. N. (2024). A systematic review on various applications and challenges in deep learning.
In AIP Conference Proceedings (Vol. 3112, No. 1). AIP Publishing.
Yuan, Q., Shen, H., Li, T., Li, Z., Li, S., Jiang, Y., ... & Zhang, L. (2020). Deep learning in
environmental remote sensing: Achievements and challenges. Remote Sensing of
Environment, 241, 111716.
Yuan, S., & Wu, X. (2021). Deep learning for insider threat detection: Review, challenges and
opportunities. Computers & Security, 104, 102221.

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