http://en.wikipedia.org/wiki/Clindamycin www.drugs.com Clindamycin Gel is used for: Treating severe acne.

It may also be used for other conditions as determined by your doctor. Clindamycin Gel is a topical lincomycin antibiotic. It works by killing sensitive bacteria that cause acne and reducing the amount of free fatty acids that irritate the skin surface. Clindagel (clindamycin phosphate) Topical Gel, 1% Clindamycin Cream is used for: Treating vaginal infections caused by certain bacteria. Clindamycin Cream is a topical lincomycin antibiotic. It works by slowing the growth of certain bacteria. What is clindamycin topical? Clindamycin is an antibiotic. Clindamycin topical prevents bacteria from growing on the skin. Clindamycin topical (for the skin) is used to treat severe acne. Clindamycin Foam
Generic Name: clindamycin phosphate Dosage Form: aerosol, foam CLINDAMYCIN PHOSPHATE FOAM, 1% NOT FOR OPHTHALMIC, ORAL, OR INTRAVAGINAL USE. Clindamycin Foam Description Clindamycin Phosphate Foam, 1% contains clindamycin phosphate, USP, a topical antibiotic for topical dermatologic use. Clindamycin phosphate is a water-soluble ester of the semi-synthetic antibiotic produced by a 7 (S)-chloro-substitution of the 7 (R)hydroxyl group of the parent antibiotic, lincomycin. Clindamycin Phosphate Foam, 1% contains clindamycin phosphate, USP, at a concentration equivalent to 10 mg clindamycin per gram in a thermolabile hydroethanolic foam vehicle consisting of cetyl alcohol, ethanol (58%), polysorbate 60, propylene glycol, purified water, and stearyl alcohol pressurized with a hydrocarbon (propane/butane) propellant.

Clindamycin Palmitate Hydrochloride Granules

Generic Name: clindamycin palmitate hydrochloride Dosage Form: granule, for oral solution Clindamycin Palmitate Hydrochloride for Oral - Not for Injection

Solution, USP

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Clindamycin Palmitate Hydrochloride for Oral Solution and other antibacterial drugs, Clindamycin Palmitate Hydrochloride for Oral Solution should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. Clindamycin palmitate hydrochloride is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid. Clindamycin Palmitate Hydrochloride for Oral Solution, USP contains clindamycin palmitate hydrochloride for reconstitution. Each 5 mL contains the equivalent of 75 mg clindamycin. Inactive ingredients: artificial cherry flavor, dextrin, ethylparaben, poloxamer 188, simethicone, sucrose.

Clindamycin Suppositories Pronunciation: KLIN-da-MYE-sin Generic Name: Clindamycin Brand Name: Cleocin Clindamycin Suppositories are used for:
Treating vaginal infections caused by certain bacteria. Clindamycin Suppositories are a topical lincomycin antibiotic. It works by blocking the production of a protein necessary for the bacteria to survive.

Clindamycin Syrup
Clindamycin syrup is usually prescribed under the brand name Dalacin C. The strength of the syrup is 75mg/5ml, that is, every 5ml of the liquid contains a dose of 75mg. Clindamycin syrup is not available in the UK so has to be imported from abroad. Synonyms : Dalatsin TS, Klimitsin, Dalacin C, Cleocin, Climicin, Clinymicin, Klindamycin, Klinicin, Sobelin and others.

Clindamycin Foam
Pronunciation: KLIN-da-MYE-sin Generic Name: Clindamycin Brand Name: Evoclin

Clindamycin Foam is used for:

Treating acne. It may also be used for other conditions as determined by your doctor. Clindamycin Foam is a topical lincomycin antibiotic. It works by killing sensitive bacteria that cause acne and reducing the amount of free fatty acids that irritate the skin surface. Evoclin (clindamycin phosphate) aerosol, foam Evoclin Foam contains clindamycin phosphate, USP, a topical antibiotic for topical

dermatologic use. Clindamycin phosphate is a water-soluble ester of the semisynthetic antibiotic. Evoclin (clindamycin phosphate) Foam, 1%, contains clindamycin phosphate,USP, at a concentration equivalent to 10 mg clindamycin per gram in a thermolabile hydroethanolic foam vehicle consisting of cetyl alcohol, ethanol (58%), polysorbate 60, potassium hydroxide, propylene glycol, purified water, and stearyl alcohol pressurized with a hydrocarbon (propane/butane) propellant.

About Clindamycin
The bacterial life cycle is somewhat different than that of human cells. This allows different antibiotics to be used to combat the growth of pathogenic bacteria. Clindamycin, like most antibiotics, takes advantage of subtle differences in the ways in which human and bacterial cells survive and works to slow the growth of bacteria, which makes it effective against many different kinds of bacteria.

Formulations
Clindamycin is an antibiotic that comes in many different forms. According to the Mayo Clinic, clindamycin can be taken orally or be injected into the body. Drugs.com also indicates that there are topical forms of clindamycin, which can come in the form of an ointment or patch.

Mechanism
As Pediatric Care Online explains, clindamycin works by preventing bacteria from making new proteins. Clindamycin blocks off a portion of the bacterial protein synthesizing machinery called the 50s portion of the ribosome. Ribosomes are needed to make new proteins. By slowing bacterial synthesis, clindamycin makes it harder for bacteria to grow.

Effectiveness
Clindamycin is an effective treatment for gram-positive aerobic bacteria (ones that use oxygen to generate energy) and also anerobic bacteria (bacteria that do not consume oxygen). Clindamycin can also be used to treat anthrax, malaria and some forms of acne. Clindamycin is also used to treat toxoplasmosis in patients with weakened immune systems or in pregnant mothers.

Pseudomembranous Colitis
The most common complication of clindamycin use is opportunistic infections from the bacteria Clostridium difficile. Clostridium difficile is a bacteria that normally (and harmlessly) colonizes the colon. Because clindamycin can eliminate the other bacteria in the colon, it can give the C. difficile bacteria the space and resources to overgrow the colon, leading to a severe infection known as pseudomembranous colitis.

Contraindications
Clindamycin use is not recommended for patients who are allergic either to clindamycin or lincomycin (a related antibiotic). It also should not be used by patients who are also taking erythromycin, as the two antibiotics have the same mechanism of action. Drugs.com also notes that

patients with intestinal problems (such as colitis or Crohn's) may not be suited for clindamycin--the same goes for patients with kidney disease or asthma.

http://en.wikipedia.org/wiki/Colloid Dispersed Phase Medium / Phases Gas

NONE (All gases are mutually miscible) Foam Example: whipped cream, Shaving cream Solid foam Examples: aerogel, styrofoam, pumice

Liquid
Liquid aerosol Examples: fog, mist, hair sprays Emulsion Examples: milk, mayonnaise, hand cream Gel Examples: agar, gelatin, jelly, opal

Solid
Solid aerosol Examples: smoke, cloud, air particulates Sol Examples: pigmented ink, blood Solid sol Example: cranberry glass

Gas

Continuous medium

Liquid

Solid