Target DPP Test Contact Number: 9667591930 / 8527521718

1. Commonly used vectors for human genome 8. A. DNA polymorphism plays important role
sequencing are in evolution and speciation.
(1) T-DNA B. 99.9% nucleotides bases are exactly same in
(2) BAC and YAC all people
(3) Expression vectors C. Chromosome 1 has the fewest genes (23) and
(4) T/A cloning vectors Y-chromosomes has most genes (2968)
D. BAC and YAC have been used in Human
2. Complete genomic sequence of the following Genome Project.
plant has been recently announced is (1) All correct
(1) Arabidopsis thaliana (2) All incorrect
(2) Tritium vulgare (3) A, B, D are correct
(3) Cucurbita pepo (4) B, C, D are correct
(4) Pisum sativum
9. The full form of ELSI is:
3. The new era of genomics started with the (1) Embedded Low Software Index
determination of (2) Ear Lung Spleen Immunity
(1) human genome sequence (3) Ethical Legal and Social Issue
(2)bacteria genome sequence (4) Endonuclease Ligase Surface Immunity
(3)discovery of PCR
(4)protein sequencing 10. The salient features of the human genome
include all except:
4. Which of the following is a stop 1. About 1.4 million SNP locations
codon 2. Functions known for less than 50% of the
discovered genes
(1)UAA
3. The actual number of genes and the initial
(2)UAG estimates are remarkable similar
(3)UGA 4. More than 98% of genome does not code for
(4)all of the above proteins

5. Which of the following was not the goal of 11. Identifying all the genes in the genome that
Human Genome Project are transcribed into RNA is called:
1. Identification of human genes Expressed Sequence Sequence
2. human genome sequence determination 1. 2.
Tag Annotation
3. store information in databases 3. Inverse PCR 4. Retrotransposition
4. Improve manpower for data analysis

6. Which of the following were not used in 12. Select the correct match
HGP? 1. Alc Jeffreys – Automated DNA sequencers
(1)Vectors like BAC and YAC 2. Frederick Sanger – Amino acid sequencing
(2) Hosts like plants and animals 3. Holley – Inverted L-shaped Structure of tRNA
(3)Protein sequencers 4. Meselson & Stahl – DNA structure
(4)DNA sequencers
13. The number of genes present on the human
7. Frederick Sanger is credited for the invention - ‘‘Y’’- chromosome, is
of 1. 321
(1)DNA sequencing method 2. 123
(2)Protein sequencing method 3. 312
(3)Both 4. 231
(4)RNA sequencing method

Page: 1
 Target DPP Test Contact Number: 9667591930 / 8527521718

14. In history of biology, human genome project 18. How many of these statements are true for
led to the development of polymorphism?
1. Bioinformatics (A) It is inheritable
2. Biosystematics (B) It arises due to mutation
3. Biotechnology
(C) It varies at the genetic level
4. Biomonitoring
(D) It is the basis of genetic mapping
15. In the human genome, the chromosomes (E) It is important for evolution and speciation
with the most and the fewest genes located on It varies from single nucleotide to large
(F)
them respectively are: scale
1. 1 and Y 2. X and Y
1. 6
3. 21 and X 4. 11 and Y
2. 5
3. 4
4. 3
16. The salient features of the human genome
include all of the following except:
The functions are unknown for over 50 % of
1.
the discovered genes. 19. Which of the following is a free-living non-
More than 2 % of the genome codes for pathogenic nematode, frequently used in the
2.
proteins. study of developmental genetics, and whose
3. Chromosome 1 has the most genes. genome has been sequenced?
Repeated sequences make up a very large 1. Arabidopsis thaliana
4. 2. Caenorhabditis elegans
portion of the human genome.
3. Drosophila melanogaster
4. Meloidogyne incognitia
17. Match each item in Column I with one in
20. If a geneticist uses the blind approach for
Column II and select the correct match from the
sequencing the whole genome of an organism,
codes given:
followed by assignment of function to different
Column
Column I segments, the methodology adopted by him is
II
called as:
Number of genes on 1. Bioinformatics
A. P. 2968
chromosome 1 2. Sequence annotation
Number of genes on Y Less than 3. Gene mapping
B. Q.
chromosome 2 4. Expressed sequence tags
Percent of genome that codes
C. R. Over 50
for proteins
Percent of discovered genes
D. S. 231
without known functions

Codes:
A B C D
1. P S Q R
2. S P Q R
3. P S R Q
4. S P R Q

Page: 2
 Target DPP Test Contact Number: 9667591930 / 8527521718

21. Given below are two statements : one is 24. Consider the given two statements:
labelled as Assertion (A) and the other is HGP [Human Genome Project]
labelled as Reason (R). was closely associated with the
Learning about non-human Assertion (A): rapid development of a new
organisms DNA sequences is area in biology called
Assertion (A):
not important for human Bioinformatics.
beings. The enormous amount of data
The Genetic code is not expected to be generated also
Reason (R):
universal. necessitated the use of high
Reason (R):
In the light of the above statements, choose the speed computational devices
most appropriate answer from the options for data storage and retrieval,
given below : and analysis.
Both (A) and (R) are True and (R) is the
1.
correct explanation of (A). Both (A) and (R) are True but (R) ​does not
1.
2. Both (A) and (R) are False. correctly explain (A).
Both (A) and (R) are True but (R) is not the 2. (A) is False but (R) ​is True.
3.
correct explanation of (A). 3. (A) is True but (R) ​is False.
4. (A) is True but (R) is False. Both (A) and (R) ​are True and (R) ​correctly
4.
explains (A).

22. Assertion(A): Specialised computer-based

programs were developed for Sanger's 25. Consider the given two statements:
sequencing method. For sequencing, the total DNA from
Reason(R): Alignment of overlapping fragments Assertion a cell is isolated and converted into
was not possible humanly. (A): random fragments of relatively
1. Both (A) and (R) are true and (R) is the smaller sizes.
correct explanation of (A). DNA is a very long polymer, and
2. Both (A) and (R) are true, but (R) is not the Reason there are technical limitations in
correct explanation of (A). (R): sequencing very long pieces of
3. (A) is true, but (R) is false. DNA.
4. (A) is false, but (R) is true.
Both (A) and (R) are True but (R) does not
23. Select the important goals of HGP from the 1.
correctly explain (A).
given options :
(i) Store the information for data analysis. 2. (A) is False but (R) is True.
(ii) Cloning and amplification of human DNA. 3. (A) is True but (R) is False.
(iii) Identify all the genes present in human Both (A) and (R) are True and (R) correctly
4.
DNA. explains (A).
(iv) Use of DNA information to trace human
history.
1. (i) and (ii) 26. Select the important goals of HGP from the
2. (ii) and (iii) given options:
3. (i) and (iii) (i) Store the information for data analysis.
4. (ii) and (iv) (ii) Cloning and amplification of human DNA.
(iii) Identify all the genes present in human
DNA.
(iv) Use of DNA information to trace human
history.
1. (i) and (ii)
2. (ii) and (iii)
3. (i) and (ii)
4. (ii) and (iv)
Page: 3
 Target DPP Test Contact Number: 9667591930 / 8527521718

27. The methodology used in human genome

sequencing that took the blind approach of Fill OMR Sheet*
simply sequencing the
whole set of genome that contained all the *If above link doesn't work, please go to test link
coding and non-coding sequence, and later from where you got the pdf and fill OMR from
assigning different there
regions in the sequence with functions, is called
as:
1. Expressed sequence tag
2. Sequence annotation
3. Chain termination
4. Physical mapping CLICK HERE to get
28. The last of the 24 human chromosomes – 22 FREE ACCESS for 2
autosomes and X and Y – to be sequenced was:
1. Chromosome 1 days of ANY
2. the X chromosome
3. the Y chromosome NEETprep course
4. Chromosome 22

29. Salient observations drawn from the human

genome project include all of the following,
except:

The human genome contains 3164.7 million

1.
bp.
The average gene consists of 3000 bases, but
sizes vary greatly, with the largest known
2.
human gene being dystrophin at 2.4 million
bases.
The total number of genes is estimated at
3.
80,000 to 1,40,000 genes.
Almost all (99.9 per cent) nucleotide bases
4.
are exactly the same in all people.

30. In how many base sequences would there

be differences in human genome?
1. 3 × 10 bp
3

2. 3 × 10 bp
6

3. 3 × 10 bp
9

4. 3 × 10 bp
12

Page: 4