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Paracetamol

Paracetamol is a non-opioid analgesic and antipyretic that inhibits prostaglandin synthesis in the CNS to reduce pain and fever, with minimal peripheral anti-inflammatory action. It is indicated for mild to moderate pain and fever but is contraindicated in patients with hypersensitivity to paracetamol, severe liver impairment, or active liver disease. Common adverse effects include nausea and rash, while severe effects can include hepatotoxicity; responsibilities include assessing pain/fever, monitoring liver function, and educating patients on dosage limits.

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8 views3 pages

Paracetamol

Paracetamol is a non-opioid analgesic and antipyretic that inhibits prostaglandin synthesis in the CNS to reduce pain and fever, with minimal peripheral anti-inflammatory action. It is indicated for mild to moderate pain and fever but is contraindicated in patients with hypersensitivity to paracetamol, severe liver impairment, or active liver disease. Common adverse effects include nausea and rash, while severe effects can include hepatotoxicity; responsibilities include assessing pain/fever, monitoring liver function, and educating patients on dosage limits.

Uploaded by

nicay.liecious
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOCX, PDF, TXT or read online on Scribd
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Nursing

Mechanisms of
Drug Order Indications Contraindications Adverse Effects Responsibilities &
Action
Precautions

Generic Inhibits Mild to Hypersensitivity Common: Nausea,


Name: prostaglandin moderate pain to paracetamol, rash 1. Assess
synthesis in (e.g., severe liver Severe:Hepatotoxi pain/fever
the CNS, headache, impairment or city, renal before and
Paracetamo reducing pain toothache, active liver impairment, after
l and fever; muscle pain), disease hypersensitivity administration.
(Acetamino minimal fever reactions (e.g., 2. Monitor liver
phen) peripheral anti- Stevens- function tests
inflammatory Johnson for prolonged
action. Syndrome) use.
Brand 3. Educate
Names: patients about
maximum daily
Tylenol, dose.
Panadol, 4. Avoid
Calpol, concurrent use
Tempra of other
paracetamol-
Classificati containing
on products.
Therapeutic
Class: Analge
sic,
Antipyretic
Pharmacologic
Class: Non-
opioid
analgesic

Dosage:

Adults: 500-
1000 mg
every 4-6
hours (Max:
4g/day)
Children: 10-
15
mg/kg/dose
every 4-6
hours (Max:
75
mg/kg/day
or 4g/day,
whichever
is lower)

Route of
administra
tion:

Oral, Rectal,
Intravenous

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