Domperidone Motilium (1 tab, 100 mg) Classification Anti-emetic and anti-vertigo Desired Dosage and Directions for use:

Acute conditions(mainly nausea, vomiting, hiccup) Adults: Two tablets (20 mg) 3 to 4 times per day, 15 to 30 minutes before meals and, if necessary, before retiring. Chronic conditions (mainly dyspepsia) Mode of Action: Domperidone is a dopamine-receptor blocking agent. Its action on the dopamine-receptors in the chemo-emetic trigger zone produces an anti-emetic effect.Interactions: Concomitant administration of anti-cholinergic drugs may inhibit the anti-dyspeptic effects of MOTILIUM. Anti-muscarinic agents and opioid analgesics may antagonize the effect of MOTILIUM MOTILIUM suppresses the peripheral effects (digestive disorders, nausea andvomiting) of dopaminergic agonists. Since MOTILIUM has gastro-kinetic effects, it could influence the absorption of concomitant orally administered medicines, particularly those with sustainedrelease or enteric coated formulations. As MOTILIUM interferes with serum prolactin levels, it may interfere with other hypoprolactinaemic agents and with some diagnostic tests. Antacids and anti-secretory agents lower the oral bioavailability of domperidone.They should be taken after meals and not before meals, i.e. they should not betaken simultaneously with MOTILIUM. Reduced gastric acidity impairs the absorption of domperidone.Oral bioavailability is decreased by prior administration of cimetidine or sodiumbicarbonate Side Effects: Allergic reactions, such as rash or urticaria, have been reported. Abdominal cramps have been reported. Dystonic reactions (extrapyramidal phenomena) may occur. Reversible raised serum prolactin levels have been observed which may lead togalactorrhoea and gynaecomastia. Hypertensive crises in patients with phaeochromocytoma may occur withadministration of domperidone. Where the blood brain barrier is not fully developed (mainly in young babies) or isimpaired, the possible occurrence of neurological side-effects cannot be totallyexcludedNursing Responsibilities:1. Assess for extra-pyramidal effects such as jerking and tongue protrusion.2. Check for hypotension Simethicone/Disflatyl Gastrointestinaldrug MOA: By its defoaming action, drug disperses or prevents formation of mucus-surrounded gas pockets in the GItract. Indication: Flatulence ,functional gastric bloating S/e:Flatus, belching Drug doesnt prevent formation of gas.>Tell patient to chew tablet before swallowing.>Advise patient that changing positions often and walking will help pass flatus : Moriamin Forte Generic name:Calcium pantothenic Indication : malnutrition, protein and vitamin deficiencies, anemia, convalescence,restoration and maintenance of body resistance, pregnancy and lactation,adjuvant in the therapy of peptic ulcer and TB. Drug classification : multivitamins and minerals Mechanism of action:Dosage : adult 1-2 cap/day; children 1 cap/day Special precaution : may color urine yellow Pregnancy risk categoryAdverse reactions : hypervitaminosis (large doses) Contraindications: contraindicated for patients with malabsorption syndrome Nursing responsibilities: Assess patient for signs of vitamin deficiency before and periodically through out therapy. Assess nutritional status through 24 h diet recall. Determine consumption of vit rich foods Ciprofloxacin Indications: Infections of the resp.tract, middle ear,paranasal sinuses,eyes,kidneys,urinary tract MOA: Inhibits bacterial DNA gyrase thus preventing replication in susceptible bacteria Contraindications: Drugs that inhibit peristalsis. Infants and children, growing adolescents .Pregnancy and lactation Side Effects:Severe and persistent diarrhea during and after treatment ADVERSE RXn Common: Nausea, diarrhea, vomiting, rash Uncommon: Anorexia, headache, dizziness, fever, GI and abdominal pain,flatulence,confusion, vertigo Nsg. Responsibility: >Assess pt for previous sensitivity reaction>Assess pt for any s/s of infection before& during treatment>Assess for adverse reactions>assess pt. &familys knowledge of drug therapy Diumide K Pharmacology: Diumide-K, a sulfonamide-type loop diuretic structurally related to bumetanide, is used to manage hypertension and edema associated with congestive heart failure, cirrhosis, and renal disease, including the nephrotic syndrome.

GENERIC NAME: mupirocin, mupirocin calcium BRAND NAME: Bactroban, Bactroban Nasal, Centany DRUG CLASS AND MECHANISM: Mupirocin is an antibiotic that is used topically (on the skin) for the treatment of impetigo, a bacterial disease of the skin caused by Staphylococcus aureus, beta-hemolytic streptococcus and Streptococcus pyogenes. Brand Name: Vastarel MR Generic Name:Trimetazidine Indication : Long treatment of coronary insufficiency, angina pectoris. Drug Classification : Anti-Anginal Drugs Mechanism of Action : acts by directly counteracting all the major metabolic disorders occurringwithin the ischemic cell. The actions of trimetazidine include limitation of intracellular acidosis, correction of disturbances of transmembrane ion exchanges, and prevention of excessive production of free radicals.decrease myocardial oxygen requirement bydecreasing the heart rate, ventricular volume, blood pressure and contractility. Insome cases, myocardial oxygen delivery is increased thru reversing coronaryarterial spasm. Dosage: 1 tab morning and evening Special Precaution: Pregnancy and Lactation Pregnancy Risk Category : Adverse Reaction : Rare cases of GI disorders. Contraindications : MAOIs (monoamine oxidase inhibitors) Form : 35 mg tablets Nursing Responsibility: use cautiously in patients with heart failure or hypertension and in elderly patients.