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2018_BP103T. PHARMACEUTICS- I (Theory) (1)

The course BP103T in Pharmaceutics-I covers the fundamentals of pharmacy, focusing on the preparation of various conventional dosage forms. It includes historical aspects, dosage forms, pharmaceutical calculations, and practical applications in laboratory settings. Students will learn to handle prescriptions, understand pharmaceutical incompatibilities, and prepare syrups, emulsions, and suppositories, among other forms.

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30 views4 pages

2018_BP103T. PHARMACEUTICS- I (Theory) (1)

The course BP103T in Pharmaceutics-I covers the fundamentals of pharmacy, focusing on the preparation of various conventional dosage forms. It includes historical aspects, dosage forms, pharmaceutical calculations, and practical applications in laboratory settings. Students will learn to handle prescriptions, understand pharmaceutical incompatibilities, and prepare syrups, emulsions, and suppositories, among other forms.

Uploaded by

aniketsharma342s
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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BP103T.

PHARMACEUTICS- I (Theory)
45 Hours
Scope: This course is designed to impart a fundamental knowledge on the preparatory
pharmacy with arts and science of preparing the different conventional dosage forms.
Objectives: Upon completion of this course the student should be able to:
 Know the history of profession of pharmacy
 Understand the basics of different dosage forms, pharmaceutical incompatibilities and
pharmaceutical calculations
 Understand the professional way of handling the prescription
 Preparation of various conventional dosage forms

Course Content:
UNIT – I 10 Hours
 Historical background and development of profession of pharmacy: History
of profession of Pharmacy in India in relation to pharmacy education, industry
and organization, Pharmacy as a career, Pharmacopoeias: Introduction to IP, BP,
USP and Extra Pharmacopoeia.
 Dosage forms: Introduction to dosage forms, classification and definitions
 Prescription: Definition, Parts of prescription, handling of Prescription and
Errors in prescription.
 Posology: Definition, Factors affecting posology. Pediatric dose calculations
based on age, body weight and body surface area.
UNIT – II 10 Hours
 Pharmaceutical calculations: Weights and measures – Imperial & Metric
system, Calculations involving percentage solutions, alligation, proof spirit and
isotonic solutions based on freezing point and molecular weight.

 Powders: Definition, classification, advantages and disadvantages,Simple &


compound powders – official preparations, dusting powders, effervescent,
efflorescent and hygroscopic powders, eutectic mixtures. Geometric dilutions.

 Liquid dosage forms: Advantages and disadvantages of liquid dosage forms.


Excipients used in formulation of liquid dosage forms. Solubility enhancement
techniques

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UNIT – III 08 Hours
 Monophasic liquids: Definitions and preparations of Gargles, Mouthwashes,
Throat Paint, Eardrops, Nasal drops, Enemas, Syrups, Elixirs, Liniments and
Lotions.
 Biphasic liquids:
 Suspensions: Definition, advantages and disadvantages, classifications,
Preparation of suspensions; Flocculated and Deflocculated suspension & stability
problems and methods to overcome.
 Emulsions: Definition, classification, emulsifying agent, test for the identification
of type ofEmulsion, Methods of preparation & stability problems and methods to
overcome.

UNIT – IV 08 Hours
 Suppositories: Definition, types, advantages and disadvantages, types of bases,
methods of preparations. Displacement value & its calculations, evaluation of
suppositories.
 Pharmaceutical incompatibilities: Definition, classification, physical, chemical
and therapeutic incompatibilities with examples.

UNIV – V 07 Hours
 Semisolid dosage forms: Definitions, classification, mechanisms and factors
influencing dermal penetration of drugs. Preparation of ointments, pastes, creams
and gels. Excipients used in semi solid dosage forms. Evaluation of semi solid
dosages forms

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BP109P. PHARMACEUTICSI (Practical)

3 Hours / week
1 . Syrups
a) Syrup IP’66
b) Compound syrup of Ferrous Phosphate BPC’68
2. Elixirs a) Piperazine citrate elixir
b) Paracetamol pediatric elixir
3.Linctus a) Terpin Hydrate Linctus IP’66

b) Iodine Throat Paint (Mandles Paint)


4. Solutions
a) Strong solution of ammonium acetate
b) Cresol with soap solution
c) Lugol’s solution
5. Suspensions
a) Calamine lotion
b) Magnesium Hydroxide mixture
c) Aluminimum Hydroxide gel
6. Emulsions a) Turpentine Liniment
b) Liquid paraffin emulsion
7. Powders and Granules
a) ORS powder (WHO)
b) Effervescent granules
c)Dusting powder
d)Divded powders
8. Suppositories
a) Glycero gelatin suppository
b) Coca butter suppository
c) Zinc Oxide suppository
8. Semisolids
a) Sulphur ointment
b) Non staining-iodine ointment with methyl salicylate
c) Carbopal gel
9. Gargles and Mouthwashes
a) Iodine gargle
b) Chlorhexidine mouthwash

Recommended Books: (Latest Editions)

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1. H.C. Ansel et al., Pharmaceutical Dosage Form and Drug Delivery System, Lippincott
Williams and Walkins, New Delhi.
2. Carter S.J., Cooper and Gunn’s-Dispensing for Pharmaceutical Students, CBS publishers,
New Delhi.
3. M.E. Aulton, Pharmaceutics, The Science& Dosage Form Design, Churchill Livingstone,
Edinburgh.
4. Indian pharmacopoeia.
5. British pharmacopoeia.
6. Lachmann. Theory and Practice of Industrial Pharmacy,Lea& Febiger Publisher, The
University of Michigan.
7. Alfonso R. Gennaro Remington. The Science and Practice of Pharmacy, Lippincott
Williams, New Delhi.
8. Carter S.J., Cooper and Gunn’s. Tutorial Pharmacy, CBS Publications, New Delhi.
9. E.A. Rawlins, Bentley’s Text Book of Pharmaceutics, English Language Book Society,
Elsevier Health Sciences, USA.
10. Isaac Ghebre Sellassie: Pharmaceutical Pelletization Technology, Marcel Dekker, INC,
New York.
11. Dilip M. Parikh: Handbook of Pharmaceutical Granulation Technology, Marcel Dekker,
INC, New York.
12. Francoise Nieloud and Gilberte Marti-Mestres: Pharmaceutical Emulsions and
Suspensions, Marcel Dekker, INC, New York.

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