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cefipime

Cefepime HCl (Maxipime) is a medication available in 1 gm and 2 gm doses, typically diluted with D5W or NS for infusion. The stability data indicates that the reconstituted drug should be refrigerated and can remain stable for 7 days at 2°C to 8°C, while at room temperature, it is stable for 24 hours. Proper storage conditions are crucial to maintain potency, as the color may darken but does not affect the drug's effectiveness.

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Mohammed Ibrahim
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7 views2 pages

cefipime

Cefepime HCl (Maxipime) is a medication available in 1 gm and 2 gm doses, typically diluted with D5W or NS for infusion. The stability data indicates that the reconstituted drug should be refrigerated and can remain stable for 7 days at 2°C to 8°C, while at room temperature, it is stable for 24 hours. Proper storage conditions are crucial to maintain potency, as the color may darken but does not affect the drug's effectiveness.

Uploaded by

Mohammed Ibrahim
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOCX, PDF, TXT or read online on Scribd
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CEFEPIME HCL (MAXIPIME ®)

1 gm--- 2 gm

USUAL DILUENTS
D5W, NS
Standard Dilutions [Amount of drug] [Infusion volume] [Infusion rate]
[0 to 2 grams] [50 ml] [30 min]
STABILITY / MISCELLANEOUS
Label: Refrigerate.
STABILITY DATA:

Reconstitu
ted
Stability Stability Vial/Powde
Drug Refrigerated Room Temp. r Notes
Cefepime for
Injection in the
dry state should
be stored at 20
to 25° C and
protected from
light. As with other
Cefepime for cephalosporins, the color
Injection in ADD- of cefepime powder, as
Vantage vials are well as its solutions tend
Cefepime for stable for 24 to darken depending on
Injection in ADD- hours at storage conditions;
Vantage vials are controlled room however, when stored as
Cefepim stable for 7 days temperature recommended, the
e in a refrigerator 20°C to 25°C product potency is not
Powder 2°C to 8°C Powder adversely affected.
Store at or below
–20°C

Thaw frozen Thaw frozen


container under container at
refrigeration 5°C room
Do not force temperature As with other
thaw by 25°C Do not cephalosporins, the color
immersion in force thaw by of Cefepime Injection tend
water baths or by immersion in to darken depending on
microwave water baths or storage conditions;
irradiation. by microwave however, when stored as
irradiation. recommended, the
The thawed The thawed product potency is not
solution remains solution remains adversely affected.
stable for 7 days stable for 24 Handle frozen product
under hours at room containers with care.
refrigeration 5°C temperature Product containers may
Cefepim (41°F). Do not 25°C (77°F). Do be fragile in the frozen

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