SwissTa

Target Common name

G-protein coupled receptor 35 GPR35
Receptor protein-tyrosine kinase erbB-2 ERBB2
Aldose reductase AKR1B1
Cyclin-dependent kinase 4/cyclin D1 CCND1 CDK4
Platelet-derived growth factor receptor beta PDGFRB
Vascular endothelial growth factor receptor 3 FLT4
Insulin-like growth factor I receptor IGF1R
Insulin receptor INSR
Epidermal growth factor receptor erbB1 EGFR
Carbonic anhydrase II CA2
Cyclin-dependent kinase 2/cyclin A CDK2 CCNA1 CCNA2
Serine/threonine-protein kinase Aurora-B AURKB
Carbonic anhydrase VII CA7
Carbonic anhydrase I CA1
Glycogen synthase kinase-3 beta GSK3B
Tyrosine-protein kinase SRC SRC
Focal adhesion kinase 1 PTK2
Vascular endothelial growth factor receptor 2 KDR
Serine/threonine-protein kinase PLK1 PLK1
Carbonic anhydrase VI CA6
Carbonic anhydrase XII CA12
Carbonic anhydrase XIV CA14
Carbonic anhydrase IX CA9
Casein kinase II alpha CSNK2A1
Hepatocyte growth factor receptor MET
Carbonic anhydrase IV CA4
Serine/threonine-protein kinase PLK4 PLK4
Carbonic anhydrase XIII CA13
Tyrosine-protein kinase TIE-2 TEK
Serine/threonine-protein kinase AKT AKT1
Serine/threonine-protein kinase Aurora-A AURKA
Carbonic anhydrase VA CA5A
Beta-secretase 1 BACE1
Mitogen-activated protein kinase kinase kinase 8 MAP3K8
Serine/threonine-protein kinase B-raf BRAF
Ephrin receptor EPHB4
Heat shock 70 kDa protein 1 HSPA1A
NUAK family SNF1-like kinase 1 NUAK1
Squalene monooxygenase (by homology) SQLE
Tyrosine-protein kinase FGR (by homology) FGR
Tyrosine-protein kinase Lyn (by homology) LYN
Glutathione reductase GSR
Troponin, cardiac muscle TNNC1 TNNT2 TNNI3
Xanthine dehydrogenase XDH
D-amino-acid oxidase DAO
Cyclooxygenase-2 PTGS2
Estrogen receptor alpha ESR1
Estrogen receptor beta ESR2
Monoamine oxidase A MAOA
Estradiol 17-beta-dehydrogenase 3 HSD17B3
Protein-tyrosine phosphatase 1B PTPN1
Arachidonate 5-lipoxygenase ALOX5
Carbonyl reductase [NADPH] 1 CBR1
Cyclin-dependent kinase 5/CDK5 activator 1 CDK5R1 CDK5
Carboxylesterase 2 CES2
Carbonic anhydrase VB CA5B
Alpha-synuclein SNCA
Acetylcholinesterase ACHE
Cytochrome P450 1A2 CYP1A2
Aldehyde dehydrogenase ALDH2
G protein-coupled receptor kinase 6 GRK6
Steroid 5-alpha-reductase 1 SRD5A1
Carbonic anhydrase III CA3
Voltage-gated potassium channel subunit Kv1.3 KCNA3
Monoamine oxidase B MAOB
Aldo-keto-reductase family 1 member C3 AKR1C3
Aldo-keto reductase family 1 member C1 AKR1C1
Steryl-sulfatase STS
Serine/threonine-protein kinase PIM1 PIM1
ALK tyrosine kinase receptor ALK
Tyrosine-protein kinase receptor UFO AXL
Macrophage migration inhibitory factor MIF
Serine/threonine-protein kinase/endoribonuclease IRE1 ERN1
Cannabinoid receptor 1 CNR1
Cannabinoid receptor 2 CNR2
Nuclear factor NF-kappa-B p105 subunit NFKB1
Voltage-gated potassium channel subunit Kv1.5 KCNA5
DNA-(apurinic or apyrimidinic site) lyase APEX1
Tyrosine-protein kinase FYN FYN
Tyrosine-protein kinase LCK LCK
Serum paraoxonase/arylesterase 1 PON1
Dual-specificity tyrosine-phosphorylation regulated kinase 1A DYRK1A
Butyrylcholinesterase BCHE
Androgen Receptor AR
Arachidonate 15-lipoxygenase ALOX15
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 PFKFB3
Quinone reductase 1 NQO1
Testis-specific androgen-binding protein SHBG
Kappa Opioid receptor OPRK1
Cytochrome P450 19A1 CYP19A1
Phosphodiesterase 4D PDE4D
Inhibitor of nuclear factor kappa B kinase beta subunit IKBKB
Neurotrophic tyrosine kinase receptor type 2 NTRK2
Transthyretin TTR
Cytochrome P450 1B1 CYP1B1
Dopamine transporter SLC6A3
Monocarboxylate transporter 4 SLC16A3
NAD-dependent deacetylase sirtuin 1 SIRT1
Telomerase reverse transcriptase TERT
G-protein coupled receptor 55 GPR55
 SwissTargetPrediction
Uniprot ID ChEMBL ID Target Class
Q9HC97 CHEMBL1293267 Family A G protein-coupled receptor
P04626 CHEMBL1824 Kinase
P15121 CHEMBL1900 Enzyme
P24385 P11802 CHEMBL1907601 Kinase
P09619 CHEMBL1913 Kinase
P35916 CHEMBL1955 Kinase
P08069 CHEMBL1957 Kinase
P06213 CHEMBL1981 Kinase
P00533 CHEMBL203 Kinase
P00918 CHEMBL205 Lyase
P24941 P78396 P20248 CHEMBL2094128 Other cytosolic protein
Q96GD4 CHEMBL2185 Kinase
P43166 CHEMBL2326 Lyase
P00915 CHEMBL261 Lyase
P49841 CHEMBL262 Kinase
P12931 CHEMBL267 Kinase
Q05397 CHEMBL2695 Kinase
P35968 CHEMBL279 Kinase
P53350 CHEMBL3024 Kinase
P23280 CHEMBL3025 Lyase
O43570 CHEMBL3242 Lyase
Q9ULX7 CHEMBL3510 Lyase
Q16790 CHEMBL3594 Lyase
P68400 CHEMBL3629 Kinase
P08581 CHEMBL3717 Kinase
P22748 CHEMBL3729 Lyase
O00444 CHEMBL3788 Kinase
Q8N1Q1 CHEMBL3912 Lyase
Q02763 CHEMBL4128 Kinase
P31749 CHEMBL4282 Kinase
O14965 CHEMBL4722 Kinase
P35218 CHEMBL4789 Lyase
P56817 CHEMBL4822 Protease
P41279 CHEMBL4899 Kinase
P15056 CHEMBL5145 Kinase
P54760 CHEMBL5147 Kinase
P0DMV8 CHEMBL5460 Other cytosolic protein
O60285 CHEMBL5784 Kinase
Q14534 CHEMBL3592 Enzyme
P09769 CHEMBL4454 Kinase
P07948 CHEMBL3905 Kinase
P00390 CHEMBL2755 Oxidoreductase
P63316 P45379 P19429 CHEMBL2095202 Unclassified protein
P47989 CHEMBL1929 Oxidoreductase
P14920 CHEMBL5485 Enzyme
P35354 CHEMBL230 Oxidoreductase
P03372 CHEMBL206 Nuclear receptor
Q92731 CHEMBL242 Nuclear receptor
P21397 CHEMBL1951 Oxidoreductase
P37058 CHEMBL4234 Enzyme
P18031 CHEMBL335 Phosphatase
P09917 CHEMBL215 Oxidoreductase
P16152 CHEMBL5586 Enzyme
Q15078 Q00535 CHEMBL1907600 Kinase
O00748 CHEMBL3180 Enzyme
Q9Y2D0 CHEMBL3969 Lyase
P37840 CHEMBL6152 Unclassified protein
P22303 CHEMBL220 Hydrolase
P05177 CHEMBL3356 Cytochrome P450
P05091 CHEMBL1935 Oxidoreductase
P43250 CHEMBL6144 Kinase
P18405 CHEMBL1787 Oxidoreductase
P07451 CHEMBL2885 Lyase
P22001 CHEMBL4633 Voltage-gated ion channel
P27338 CHEMBL2039 Oxidoreductase
P42330 CHEMBL4681 Enzyme
Q04828 CHEMBL5905 Enzyme
P08842 CHEMBL3559 Enzyme
P11309 CHEMBL2147 Kinase
Q9UM73 CHEMBL4247 Kinase
P30530 CHEMBL4895 Kinase
P14174 CHEMBL2085 Enzyme
O75460 CHEMBL1163101 Enzyme
P21554 CHEMBL218 Family A G protein-coupled receptor
P34972 CHEMBL253 Family A G protein-coupled receptor
P19838 CHEMBL3251 Other cytosolic protein
P22460 CHEMBL4306 Voltage-gated ion channel
P27695 CHEMBL5619 Enzyme
P06241 CHEMBL1841 Kinase
P06239 CHEMBL258 Kinase
P27169 CHEMBL3167 Enzyme
Q13627 CHEMBL2292 Kinase
P06276 CHEMBL1914 Hydrolase
P10275 CHEMBL1871 Nuclear receptor
P16050 CHEMBL2903 Enzyme
Q16875 CHEMBL2331053 Enzyme
P15559 CHEMBL3623 Enzyme
P04278 CHEMBL3305 Secreted protein
P41145 CHEMBL237 Family A G protein-coupled receptor
P11511 CHEMBL1978 Cytochrome P450
Q08499 CHEMBL288 Phosphodiesterase
O14920 CHEMBL1991 Kinase
Q16620 CHEMBL4898 Kinase
P02766 CHEMBL3194 Secreted protein
Q16678 CHEMBL4878 Cytochrome P450
Q01959 CHEMBL238 Electrochemical transporter
O15427 CHEMBL2073663 Electrochemical transporter
Q96EB6 CHEMBL4506 Eraser
O14746 CHEMBL2916 Enzyme
Q9Y2T6 CHEMBL1075322 Family A G protein-coupled receptor
Probability* Known actives (3D/2D)
11/ 2
11/ 1
12/ 8
11/ 1
11/ 1
11/ 1
11/ 2
11/ 1
11/ 2
11/ 6
11/ 1
11/ 3
1 1 / 17
1 1 / 15
11/ 1
11/ 1
11/ 1
11/ 2
11/ 2
11/ 8
1 1 / 35
1 1 / 14
1 1 / 43
11/ 1
11/ 2
11/ 7
11/ 1
1 1 / 21
11/ 1
11/ 1
11/ 1
11/ 9
11/ 5
11/ 1
11/ 1
11/ 1
11/ 1
11/ 1
11/ 1
11/ 1
11/ 1
0.174646371539 1 / 1
0.119403562123 0 / 1
0.119403562123 0 / 3
0.11150186548 0 / 1
0.11150186548 0 / 3
0.11150186548 0 / 43
0.11150186548 0 / 61
0.11150186548 0 / 34
0.11150186548 0 / 19
0.11150186548 2 / 0
0.11150186548 0 / 1
0.11150186548 0 / 1
0.11150186548 0 / 6
0.11150186548 1 / 0
0.11150186548 0 / 9
0.11150186548 1 / 0
00/ 12
00/ 3
00/ 1
00/ 1
00/ 3
00/ 7
00/ 7
00/ 38
00/ 1
00/ 1
00/ 4
00/ 2
00/ 1
00/ 1
00/ 5
00/ 1
00/ 10
00/ 9
00/ 2
00/ 1
00/ 1
00/ 1
00/ 2
00/ 1
00/ 10
00/ 3
00/ 5
00/ 5
00/ 2
00/ 13
00/ 1
00/ 1
00/ 3
00/ 1
00/ 1
00/ 1
00/ 1
00/ 1
00/ 2
00/ 1
00/ 1
00/ 1
00/ 1