LG 1 (Coronary Heart Disases)
LG 1 (Coronary Heart Disases)
Epidemiological transition
Demographic transition
Changes in ecology and lifestyle
– Industrialization
– Urbanization
– Motor vehicles
– Air pollution
– Changes in diet,
– Sedentary life,
– Use of tobacco products,
– Alcohol and other drugs
Risk factors
Smoking
– it is responsible for 25% of CHD deaths under 65
years of age in men.
– The risk of developing CHD is directly related to the
number of cigarettes smoked per day.
– Its influence is synergistic with other risk factors
(HTN & elevated serum cholesterol).
Risk factors
Smoking
– The risk declines quite substantially within one year
of stopping smoking
– The risk of a fatal recurrence of MI may be reduced
by 50% after giving up smoking.
Risk factors
Hypertension
Diabetes
– The risk of CHD is 2-3 times higher in diabetics than
in non-diabetics.
– CHD is responsible for 30 to 50% of deaths in
diabetics over the age of 40 years in industrialized
countries.
Oral contraceptives
– Women using oral contraceptives have higher
systolic and diastolic blood pressure.
– The risk of myocardial infarction in women seems to
be increased by oral contraceptives.
Risk factors
Genetic factors
– A family history of CHD is known to increase the risk
of premature death.
– Genetic factors are probably the most important
determinants of a given individual's TC and LDL.
Physical inactivity
– Regular physical exercise increases the
concentration of HDL and decreases both body
weight and blood pressure .
Risk factors
Type A personality
– Type A behavior is associated with competitive
drive, restlessness, hostility and a sense of urgency
or impatience.
Alcohol
– High alcohol intake (75 g or more per day) is an
independent risk factor for CHD, hypertension and
all cardio-vascular diseases.
Prevention of CHD
Primary prevention
– Population strategy
Dietary changes
Smoking cessation (smoke-free society)
Blood pressure lowering
Physical activity
– High risk strategy
Identifying risk
Special advice
Secondary prevention
Interventions in Population strategy
1. Dietary changes :
– reduction of fat intake to 20-30% of total energy intake
– consumption of saturated fats must be limited to < 10% of
total energy intake
– a reduction of dietary cholesterol to below 100 mg per
1000 kcal per day
– an increase in complex carbohydrate consumption
(vegetables, fruits, whole grains and legumes)
– avoidance of alcohol consumption
– reduction of salt intake to 5 g daily or less
Interventions in Population strategy