Case Study on a Client with HTN
Case Study on a Client with HTN
Ronald Sanford, age 37 years, is diagnosed with essential hypertension. His blood
pressure has been ranging between 148- and 176-mm Hg systolic and 90 and 110 mm Hg
diastolic. His average blood pressure is 160/94 mm Hg.
There is a strong family history of hypertension and stroke on both sides of the family.
Mr. Sanford is married, with two school-age children. He works full-time as a loading
dock supervisor for a long-distance trucking company. His elevated blood pressure was
found during a routine physical examination. He reports no other manifestations. At this
time, there is no evidence of renal insufficiency or retinopathy.
Mr. Sanford is to begin taking lisinopril, 10 mg daily, and hydrochlorothiazide, 50 mg
daily.
1. Lisinopril is an angiotensin-converting enzyme inhibitor (ACEI). How will this
type of drug contribute to the control of Mr. Sanford's blood pressure?
Lisinopril, as ACEI, will contribute to controlling Mr. Sanford's blood pressure by:
blocking the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor.
Inhibiting angiotensin II production decreases constriction of blood vessels.
The relaxation of blood vessels leads to vasodilation. These effects will help lower Mr.
Sanford's blood pressure by reducing peripheral resistance and making it easier for the
heart to pump blood. Furthermore, ACEIs like Lisinopril can also reduce the workload on
the heart, which may help manage hypertension and reduce the risk of cardiovascular
complications.
2. Describe the antihypertensive action of hydrochlorothiazide.
A. Hydrochlorothiazide (HCTZ) is a diuretic medication that improves urine production and
removes excess fluid and sodium from the body. As a result, sodium and chloride ions are not
reabsorbed by the kidneys, which leads to a decrease in blood volume and, subsequently, a
decrease in blood pressure. Hypertension can be effectively treated with this antihypertensive
effect because it reduces the workload on the heart and blood vessels.
3. What does Mr. Sanford need to know about taking his medications and avoiding
adverse effects?
Mr. Sanford should know the following to avoid adverse effects and take his medications
effectively:
Ensure he takes the right medication, at the right dose, at the right time, and for the full
duration recommended.
Encourage him to monitor his blood pressure at home and report any significant changes
to his healthcare provider.
Follow up with his provider: Schedule regular check-ups to assess the medication's
effectiveness and monitor for potential side effects.
Report side effects: Encourage him to report any unusual symptoms or side effects to his
provider immediately.
Be aware of potential drug interactions: Tell him about over-the-counter medications,
supplements, and herbal products and advise him to consult his doctor before taking new
medications.
Recommend dosage instructions: Warn him against taking more or less of the medication
than prescribed and caution him against stopping or skipping doses without consulting his
provider.
By understanding these key points, Mr. Sanford can take his medications safely and effectively,
minimizing adverse effects.
6. What does Mr. Sanford need to know about taking atenolol to achieve maximum
therapeutic benefit?
A. It is important that Mr. Sanford takes atenolol regularly, at the same time each day, and not
skip or stop taking it without consulting his doctor first. In addition, he should inform his
provider if he has any symptoms or side effects.
7. After 6 months of this drug therapy, Mr. Sanford's blood pressure is maintained
at 124 to 138 mm Hg systolic and 78 to 88 mm Hg diastolic. However, he complains that he
doesn't seem to have the energy he used to have and that he is having some decrease in
sexual activity. What should you tell Mr. Sanford about these concerns and their
relationship to the addition of Atenolol to his medication regimen?
A. I would tell Mr. Sanford that fatigue and decreased sexual activity are common side effects of
atenolol and other beta-blockers. I would reassure him that his blood pressure is well-controlled,
but discuss the possibility of adjusting his medication regimen or exploring other causes of his
symptoms with his provider.
Reference
Sinha, S. (2023). Lisinopril uses, dosage, side effects & warnings. Drugs.com.
https://www.drugs.com/lisinopril.html
Smith, D. K., Lennon, R. P., & Carlsgaard, P. B. (2020, March 15). Managing hypertension
using combination therapy. American Family Physician.
https://www.aafp.org/pubs/afp/issues/2020/0315/p341.html