BBOC407 Module 1
BBOC407 Module 1
INTRODUCTION TO BIOLOGY
Anything less than a complete structure of a cell does not ensure independent living.
Hence, cell is the fundamental structural and functional unit of all living organisms.
Nucleus
• The nucleus contains the hereditary material
of the cell, the DNA.
• It sends signals to the cells to grow, mature,
divide and die.
• The nucleus is surrounded by the nuclear
envelope that separates the DNA from the
rest of the cell.
• The nucleus protects the DNA and is an
integral component of a plant’s cell
structure.
Cell Organelles
Cells are composed of various cell organelles that perform certain specific functions to
carry out life’s processes. The different cell organelles, along with its principal functions,
are as follows:
Endoplasmic reticulum
The endoplasmic reticulum is involved in the
transportation of substances throughout the cell. It
plays a primary role in the metabolism of
carbohydrates, synthesis of lipids, steroids and
proteins.
Golgi Bodies
Golgi bodies are called the cell’s post office as it is
involved in the transportation of materials within the
cell.
Ribosome
Ribosomes are the protein synthesizers of the
cell.
Mitochondria
The mitochondrion is called “the powerhouse of
the cell.” It is called so because it produces ATP –
the cell’s energy currency.
Lysosomes
Lysosomes protect the cell by engulfing the
foreign bodies entering the cell and help in cell
renewal. Therefore, they are known as the cell’s
suicide bags.
Chloroplast Vacuoles
Chloroplasts are the primary organelles Vacuoles store food, water, and other waste
for photosynthesis. It contains the materials in the cell.
pigment called chlorophyll.
Functions of Cell
A cell performs major functions essential for the growth and development of an
organism. Important functions of cell are as follows:
• Provides Support and Structure
• Facilitate Growth Mitosis
• Allows Transport of Substances
• Energy Production
• Aids in Reproduction
Plant Cell and Animal Cell
Plant Cell Animal cell
Cell Shape Square or rectangular in shape Irregular or round in shape
Eukaryotes possess a cell wall, which supports and protects the plasma
membrane. The cell is surrounded by the plasma membrane and it
controls the entry and exit of certain substances.
• The nucleus contains DNA, which is • Present in only plant cells, chloroplasts
responsible for storing all genetic are the subcellular sites of
information. The nucleus is surrounded by photosynthesis.
the nuclear membrane. Within the nucleus • The endoplasmic reticulum helps in the
exists the nucleolus, and it plays a crucial transportation of materials. Besides
role in synthesizing proteins. these, there are also other cell
• Eukaryotic cells also contain mitochondria, organelles that perform various other
which are responsible for the creation of functions and these include ribosomes,
energy, which is then utilized by the cell. lysosomes, Golgi bodies, cytoplasm,
chromosomes, vacuoles and
centrosomes.
Prokaryotes Eukaryotes
Cell size Ranges in size from 0.2 μm – 2.0 Size ranges from 10 μm – 100 μm in
μm in diameter diameter
Cell wall Usually present; chemically When present, chemically simple in
complex in nature nature
Flagella The flagella are smaller in size The flagella are larger in size
Uses
1. Research: ESCs are used to study human development, and to identify factors that
affect cell differentiation and reprogramming.
2. Cell therapy: ESCs can be used to regenerate or repair diseased tissue and organs.
3. Drug development: ESCs can be used to test the toxicity of new chemical entities
that could become drugs.
2. Induced pluripotent stem cells: Created in a lab by reprogramming adult cells, such as
skin cells . They can be reprogrammed to have the same properties as embryonic stem
cells (ESCs).
Uses
Drug screening: iPSCs can be used to model diseases and screen drugs.
Cell therapy: iPSCs can be used to create cells that can treat diseases like diabetes,
leukemia, and neurological disorders.
Disease modeling: iPSCs can be used to model diseases like Alzheimer's disease, liver
disease, and spinal cord injury.
3. Adult stem cells: Derived from adult tissue, such as bone marrow or placental
tissue
Conditions treated with adult stem cells
Heart disease: Stem cell therapy can help with heart attacks and cardiac disease.
Rheumatoid arthritis: Mesenchymal stem cells can reduce inflammation and stabilize
the immune system.
Spinal cord injuries: Hematopoietic stem cells (HSCs) can be used to treat spinal cord
injuries.
Autoimmune diseases: Stem cells can turn into the cells of damaged organs.
Liver cirrhosis: HSCs can be used to treat liver cirrhosis.
Peripheral vascular disease: HSCs can be used to treat peripheral vascular disease.
4. Mesenchyme stem cells: Derived from connective tissue, such as that surrounding
organs and other tissues . Mesenchymal stem cells (MSCs) are multipotent stem cells
that can differentiate into many types of cells, including bone, cartilage, and muscle
cells.
MSCs are being studied as a treatment for immune-mediated diseases.
MSCs are being used to repair skeletal tissue.
MSCs are being used to modulate tissue and immune cells.
MSCs are being used to treat injured tissues.
5. Hematopoietic stem cells: Blood-forming stem cells that can create red blood cells,
white blood cells, and platelets . Hematopoietic stem cells (HSCs) are immature
cells that can develop into all types of blood cells. They are also known as blood
stem cells.
HSCs are found in bone marrow and peripheral blood
HSCs produce blood cells throughout a person's life
HSCs respond to acute needs like infection or injury
HSCs are used to treat many blood cell diseases, such as leukemias and autoimmune
disorders
HSCs are used in bone marrow transplants to replace or rebuild a patient's
hematopoietic system
6. Peripheral blood stem cells: Can be isolated from a blood sample and can create
many different cells in the blood and immune system
7. Neural stem cells: Can create neurons, astrocytes, and oligodendrocytes
Embryonic stem cells.
• These stem cells come from embryos that are 3 to 5 days old.
• At this stage, an embryo is called a blastocyst and has about 150 cells.
• These are pluripotent stem cells, meaning they can divide into more stem cells
or can become any type of cell in the body.
• This versatility allows embryonic stem cells to be used to regenerate or repair
diseased tissue and organs.
Adult stem cells.
• These stem cells are found in small
numbers in most adult tissues, such as bone
marrow or fat.
• Compared with embryonic stem cells, adult
stem cells have a more limited ability to
give rise to various cells of the body.
• Until recently, researchers thought adult
stem cells could create only similar types of
cells. For instance, researchers thought that
stem cells residing in the bone marrow
could give rise only to blood cells.
• However, emerging evidence suggests that
adult stem cells may be able to create
various types of cells. For instance, bone
marrow stem cells may be able to create
bone or heart muscle cells.
• This research has led to early-stage clinical
trials to test usefulness and safety in
people. For example, adult stem cells are
currently being tested in people with
neurological or heart disease.
Adult cells altered to have properties of
embryonic stem cells.
• Induced pluripotent stem (iPS) cells, are a type
of pluripotent stem cell derived from adult
somatic cells that have been genetically
reprogrammed to an embryonic stem (ES) cell-
like state through the forced expression of
genes and factors important for maintaining
the defining properties of ES cells.
• This new technique may allow use of
reprogrammed cells instead of embryonic stem
cells and prevent immune system rejection of
the new stem cells.
• However, scientists don't yet know whether
using altered adult cells will cause adverse
effects in humans.
• Researchers have been able to take regular
connective tissue cells and reprogram them to
become functional heart cells. In studies,
animals with heart failure that were injected
with new heart cells experienced improved
heart function and survival time.
Application Description
Tissue Engineering Stem cells combined with biomaterials can engineer tissues
and organs for transplantation. This approach holds promise
for creating replacement tissues and organs, addressing the
shortage of donor organs, and reducing the risk of rejection.
Biomaterial Integration Stem cells can be integrated into various biomaterial
scaffolds, providing a platform for tissue regeneration and
repair. Engineers design and optimize these scaffolds to
mimic the natural microenvironment and guide stem cell
differentiation
Bioprinting Stem cell-based bioprinting involves the precise deposition
of stem cells and biomaterials to create complex three-
dimensional structures. This technology enables the
fabrication of tissue constructs with defined architectures,
suitable for transplantation.
Drug Screening and Stem cell-based models can be used for drug screening and
Development development, providing a more accurate representation of
human biology than traditional cell lines. Engineers develop
high-throughput platforms for screening potential drugs and
assessing their safety and efficacy.
Gene Therapy Engineers design stem cell-based gene delivery systems for gene
therapy applications. Stem cells can serve as vectors for delivering
therapeutic genes to target tissues, offering potential treatments for
genetic disorders and other diseases.
Disease Modeling Stem cells are used to model diseases in the laboratory, providing
insights into disease mechanisms and testing personalized therapies
Biomolecules
A biomolecule is a chemical compound found in living
organisms.
These include chemicals that are composed of mainly carbon, hydrogen,
oxygen, nitrogen, sulfur and phosphorus. Biomolecules are the building blocks
of life and perform important functions in living organisms.
It aids organisms to grow, sustain, and reproduce. They are involved in building
organisms from single cells to complex living beings like humans, by interacting
with each other. The diversity in their shape and structure provides diversity in
their functions.
Property Description
Chemical Composition. Composed of carbon, hydrogen, and oxygen atoms in a ratio of
1:2:1, respectively
Structure Consists of chains or rings of sugar molecules.
Solubility Most carbohydrates are soluble in water due to their
hydrophilic nature, except for some larger polysaccharides
Sweetness Monosaccharides and disaccharides are generally sweet-
tasting, while polysaccharides are not.
Energy Source The primary source of energy for living organisms, providing 4
calories per gram upon digestion.
Storage Stored as glycogen in animals and as starch in plants for energy
reserves
Structural Function Act as building blocks for cell walls in plants (cellulose) and
exoskeletons in arthropods (chitin).
Biological Significance Essential for cellular processes such as metabolism, cell
signaling, and immune system functioning.
Functions of Carbohydrates
Function Description
Energy Source Carbohydrates serve as the primary source of energy for the body,
providing fuel for various physiological processes. Glucose, derived
from carbohydrates, is particularly vital for brain function and muscle
activity.
Structural In organisms, carbohydrates play a crucial role in providing structural
Support support. For instance, cellulose, a complex carbohydrate found in plant
cell walls, offers rigidity and strength, contributing to the overall
structural integrity of plants.
Storage of Carbohydrates are stored in the body as glycogen in the liver and
Energy muscles. When energy demand increases, glycogen is broken down into
glucose to meet the energy requirements, maintaining blood glucose
levels within a normal range.
Facilitate Dietary fibers, a type of carbohydrate found in plant-based foods, aid in
Digestion digestion by promoting regular bowel movements, preventing
constipation, and supporting a healthy digestive system.
Cellular Carbohydrates on cell surfaces play a crucial role in cell recognition and
Communicatio communication. They help cells identify and interact with each other,
n facilitating various physiological processes such as immune responses
and tissue development.
Flavour and Texture Carbohydrates contribute to the taste, texture, and appearance of
foods. They enhance the flavor of foods, provide sweetness, and
contribute to the texture of baked goods, making them palatable
and appealing to consumers
Metabolic Carbohydrates participate in metabolic regulation by influencing
Regulation insulin secretion and blood glucose levels. Maintaining proper
carbohydrate intake and metabolism is essential for preventing
metabolic disorders such as diabetes
Fuel for Exercise During physical activity, carbohydrates provide the necessary
energy to sustain muscle contractions and endurance. Athletes
often rely on carbohydrate-rich foods to fuel their performance
and enhance recovery after exercise.
Nucleic acids An History
• DNA was discovered in 1869 by a Swiss biochemist, Friedrich Miescher. He wanted to
determine the chemical composition of leucocytes (white blood cells), his source of
leucocytes was pus from fresh surgical bandages.
• Although initially interested in all the components of the cell, Miescher quickly focused
on the nucleus because he observed that when treated with acid, a precipitate was
formed which he called ‘nuclein’.
• Miescher, Richard Altmann and Albrecht Kossel further characterized ‘nuclein’ and the
name was changed to nucleic acid by Altmann.
• Kossel went on to show that nucleic acid contained purine and pyrimidine bases, a
sugar and phosphate.
• Work in the 1930s from many scientists further characterized nucleic acids including the
identification of the four bases and the presence of deoxyribose, hence the name
deoxyribonucleic acid (DNA).
• Erwin Chargaff had found that DNA molecules from a particular species always
contained the same amount of the bases cytosine (C) and guanine (G) and the same
amount of adenosine (A) and thymine (T). So, for example, the human genome contains
20% C, 20% G, 30% A and 30% T.
• Nucleic acids are long-chain polymeric molecules, T
• The monomer (the repeating unit) is known as the nucleotides and hence sometimes
nucleic acids are referred to as polynucleotides.
• The basic nucleic acid structure is similar to a chain of molecules composed of identical
series of nucleotides.
• Every nucleic acid encompasses four of five possible nitrogen-containing bases, which
are,
Uracil (U), adenine (A), thymine (T), guanine (G), and cytosine (C).
Pyrimidine's Purines
Uracil (U) Adenine (A)
Thymine (T) Guanine (G)
Cytosine (C)
Nucleic acids, including DNA and RNA, play diverse and fundamental roles in the
functioning of living organisms.
As the carriers of genetic information, DNA molecules encode the instructions required for
the development, growth, and reproduction of organisms, while RNA molecules
participate in protein synthesis and gene expression regulation.
Beyond their roles in genetic processes, nucleic acids also contribute to energy transfer
through molecules like ATP, catalyze biochemical reactions as ribozymes, and participate
in immune responses and chemical signaling pathways within cells.
Messenger RNA (mRNA): Transfers genetic sequence data between DNA and
ribosomes, regulating protein synthesis and carrying directions from DNA
(deoxyribonucleic acid) in the nucleus to the ribosome.
Ribosomal RNA (rRNA): Studies the Deoxyribonucleic acid sequence and catalyzes
peptide bond formation.
Difference Between DNA and RNA
Properties of Nucleic Acids
Property Description
Polarity Nucleic acids exhibit polarity, with distinct 5' (five-prime) and 3' (three-prime)
ends. This polarity arises from the orientation of the sugar-phosphate backbone,
where the 5' end contains a phosphate group attached to the 5' carbon of the
sugar molecule, and the 3' end terminates with a hydroxyl group on the 3'
carbon.
Double Helix DNA molecules possess a double helix structure, characterized by two
Structure complementary polynucleotide strands winding around each other in a right-
handed manner. This structure provides stability and protection to the genetic
information encoded within the DNA molecule and facilitates replication and
transcription processes.
Base Pairing Nucleic acids exhibit specific base pairing rules, where adenine (A) pairs with
thymine (T) in DNA or uracil (U) in RNA via hydrogen bonds, and cytosine (C)
pairs with guanine (G). This complementary base pairing ensures the accurate
replication and transmission of genetic information during cellular processes.
Hydrogen Hydrogen bonding plays a crucial role in stabilizing the structure of nucleic
Bonding acids. Within the double helix of DNA, hydrogen bonds form between
complementary base pairs, contributing to the structural integrity and specificity
of the molecule. These bonds are relatively weak individually but collectively
provide stability to the DNA double helix
Acidic Nucleic acids are acidic molecules due to the presence of phosphate groups
Nature in their structure. The negatively charged phosphate groups confer an
overall negative charge to the nucleic acid molecule, influencing its
interactions with other molecules and its behavior in biochemical
processes.
Based on the chemical nature, structure, shape, and solubility, proteins are
classified as:
Simple proteins: They are composed of only amino acid residue. On hydrolysis,
these proteins yield only constituent amino acids. It is further divided into:
Fibrous protein: Keratin, Elastin, Collagen
Globular protein: Albumin, Globulin, Glutelin, Histones
Property Description
Structure Proteins exhibit a hierarchical structure, consisting of primary,
secondary, tertiary, and quaternary levels of organization. The
primary structure refers to the linear sequence of amino acids
linked by peptide bonds. Secondary structure involves folding
patterns such as alpha helices and beta sheets, while tertiary
structure refers to the three-dimensional arrangement of the
entire polypeptide chain. Quaternary structure arises when
multiple polypeptide chains assemble to form a functional
protein complex.
Amino Acid Proteins are composed of amino acids, which are organic
Composition molecules containing an amino group, a carboxyl group, and a
variable side chain. There are 20 standard amino acids, each
with a unique side chain that imparts specific chemical and
structural properties to the protein. The sequence and
composition of amino acids determine the structure and
function of the protein molecule
Functional Proteins exhibit remarkable functional diversity, serving as enzymes,
Diversity structural components, transporters, receptors, antibodies, hormones,
and molecular motors, among other roles. Enzymes catalyze
biochemical reactions, while structural proteins provide support and
stability to cells and tissues. Transport proteins facilitate the movement
of molecules across biological membranes, and receptors mediate
cellular signaling pathways. The diverse functions of proteins reflect
their versatility and importance in biological systems.
Folding and Proteins undergo folding into their native three-dimensional structures,
Stability driven by interactions between amino acid side chains and the
surrounding environment. The folding process is crucial for protein
function, as it determines the specific binding sites and active sites
necessary for interactions with other molecules. Proteins can also
exhibit different levels of stability, influenced by factors such as
temperature, pH, and the presence of cofactors or ligands.
Denaturation Proteins can undergo denaturation, a process in which their native
structure is disrupted, leading to loss of function. Denaturation can be
induced by various factors, including heat, pH extremes, organic
solvents, and chaotropic agents. While denatured proteins may lose
their biological activity, they often retain their primary structure,
allowing for the possibility of renaturation under favorable conditions
Solubility The solubility of proteins varies depending on their amino acid composition and
the surrounding environment. Some proteins are soluble in water, while others are
insoluble and may form aggregates or precipitates. Protein solubility is influenced
by factors such as pH, temperature, ionic strength, and the presence of denaturing
agents or binding partners. Understanding the solubility behavior of proteins is
essential for their purification, characterization, and functional studies.
Functions of Proteins
Function Description
Enzymatic Proteins serve as enzymes, catalyzing biochemical reactions within cells and
Activity organisms. Enzymes facilitate the conversion of substrates into products by
lowering the activation energy of reactions, thereby accelerating metabolic
processes essential for life.
Structural Proteins provide structural support to cells, tissues, and organs in living
Support organisms. Structural proteins such as collagen, elastin, and keratin contribute to
the mechanical strength, elasticity, and integrity of various biological structures,
including bones, skin, hair, and connective tissues
Transport Proteins function as carriers and transporters, facilitating the movement of
molecules across biological membranes and within the circulatory system.
Transport proteins, such as hemoglobin, transport gases like oxygen and carbon
dioxide in the blood, while membrane transporters regulate the passage of ions
and molecules across cell membranes.
Signaling Proteins play crucial roles in cellular signaling pathways, transmitting and
modulating signals that regulate various physiological processes. Signaling
proteins, such as receptors, transducers, and kinases, relay information from
extracellular stimuli to intracellular effectors, controlling cell growth,
differentiation, and responses to environmental cues.
Immune Proteins are essential components of the immune system, participating in
Response the recognition, response, and defense against pathogens and foreign
substances. Antibodies, also known as immunoglobulins, are proteins
produced by the immune system that bind to specific antigens, marking
them for destruction by immune cells.
Hormonal Proteins serve as hormones and hormone receptors, regulating numerous
Regulation physiological processes and maintaining homeostasis in the body.
Hormones, such as insulin, glucagon, and growth hormone, are signaling
proteins that coordinate metabolism, growth, reproduction, and other
functions by binding to specific receptors on target cells.
Muscle Proteins play a central role in muscle contraction, enabling movement and
Contraction locomotion in animals. Contractile proteins, including actin and myosin,
interact to generate the force required for muscle contraction and
movement. The coordinated action of these proteins underlies processes
such as muscle contraction, relaxation, and control of motor functions.
Lipids
• Lipids are organic compounds that are fatty acids or derivatives of fatty acids,
which are insoluble in water but soluble in organic solvents.
• In the human body, these molecules can be synthesized in the liver and are
found in oil, butter, whole milk, cheese, fried foods and also in some red
meats.
Functions of Enzymes
Function Description
.
Catalysis Enzymes serve as biological catalysts, accelerating chemical
reactions by lowering the activation energy required for the
conversion of substrates into products. By facilitating the
formation of transition states and stabilizing reaction
intermediates, enzymes enhance the rate of reactions without
being consumed in the process.
Specificity Enzymes exhibit high specificity for their substrates,
recognizing and binding to specific molecules or chemical
groups through complementary interactions at the enzyme's
active site. This substrate specificity ensures that enzymes
selectively catalyze particular reactions, leading to precise
control over metabolic pathways and cellular processes.
Regulation Enzyme activity is tightly regulated to maintain metabolic homeostasis and
respond to changing environmental conditions. Regulation may occur
through various mechanisms, including allosteric regulation, covalent
modification, and feedback inhibition, which modulate enzyme activity in
response to signals such as substrate availability, cellular energy levels, or
hormonal signal
Metabolic Enzymes participate in metabolic pathways, sequences of interconnected
Pathways biochemical reactions that convert substrates into products. Within these
pathways, enzymes catalyze specific steps, regulating the flow of metabolites
and ensuring the coordinated synthesis, degradation, and inter-conversion of
biomolecules essential for cellular function and survival.
Signal Enzymes play key roles in signal transduction pathways, transmitting
Transduction extracellular signals into intracellular responses that regulate various cellular
processes. For example, protein kinases and phosphatases catalyze the
phosphorylation and dephosphorylation of target proteins, respectively,
thereby modulating their activity and mediating cellular responses to stimuli.
DNA Enzymes are involved in DNA replication and repair processes, ensuring the
Replication faithful transmission of genetic information and maintaining genomic
and Repair stability. DNA polymerases catalyze the synthesis of new DNA strands
during replication, while DNA repair enzymes correct errors and lesions in
the DNA sequence, minimizing mutations and preserving genetic integrity.
Digestion Enzymes facilitate the breakdown of macromolecules into smaller, more
readily absorbable units during the process of digestion. Digestive
enzymes, such as proteases, lipases, and carbohydrases, hydrolyze
proteins, fats, and carbohydrates, respectively, into amino acids, fatty
acids, and sugars that can be absorbed and utilized by the body for energy
and growth.
Properties of Enzymes
Property Description
Specificity Enzymes exhibit specificity in substrate recognition and catalytic activity,
interacting with specific substrates to facilitate particular biochemical
reactions. This specificity arises from the complementary shapes and
chemical properties of the enzyme's active site and the substrate molecule.
Catalytic Enzymes are catalysts that accelerate biochemical reactions by lowering the
activation energy required for the conversion of substrates into products. By
stabilizing the transition state of the reaction, enzymes facilitate the
formation of product molecules more rapidly and efficiently.
Efficiency Enzymes are highly efficient catalysts, often capable of increasing reaction
rates by millions to billions of times compared to uncatalyzed reactions. This
high efficiency allows cells to carry out metabolic processes at rates
compatible with life despite relatively mild physiological conditions.
Regulation Enzyme activity is regulated by various factors, including substrate
concentration, pH, temperature, and the presence of inhibitors or
activators. These regulatory mechanisms ensure that enzyme activity is
finely tuned to meet the changing metabolic demands of cells and maintain
homeostatic
Reusability Enzymes are reusable catalysts that can catalyze multiple rounds of
substrate conversion without being consumed in the reaction. After
facilitating a reaction, enzymes remain unchanged and available to
catalyze subsequent reactions, making them highly economical and
efficient components of cellular metabolism.
Sensitivity Enzyme activity is sensitive to changes in environmental conditions, such
as temperature and pH, which can influence enzyme structure and
function. Small deviations from optimal conditions can significantly affect
enzyme activity, leading to alterations in metabolic pathways and cellular
function
VITAMINS
They are classified into two categories: fat-soluble vitamins (A, D, E, and K) and water-
soluble vitamins (B vitamins and vitamin C). Fat-soluble vitamins are absorbed along with
fats in the diet and are stored in the body's fatty tissues, while water-soluble vitamins
dissolve in water and are excreted in urine when consumed in excess.
Vitamin Chemical Description Plant Source Animal
Name Source
Vitamin Retinol Essential for vision, Immune Carrot, sweat Liver, fish
function , Mucous membrane, potatoes, oil, eggs,
A maintaining healthy skin, and cell spinach, kale, dairy
growth and differentiation broccoli products
Vitamin Thiamine Energy metabolism, nerve function, Whole Pork, beef,
and carbohydrate metabolism. grains, organ
B₁ legumes, meats,
nuts, seeds whole
grains
Vitamin Biotin Essential for carbohydrate, fat, and Nuts, seeds, Eggs, liver,
protein metabolism sweet salmon,
B₇ potatoes, pork
avocado
Vitamin Folate Crucial for DNA synthesis, cell Leafy greens, Liver, eggs
Folic acid division, and the formation of red asparagus,
B₉ blood cells. It plays a vital role in fetal citrus fruits,
development, preventing birth beans fortified
defects. grains, lentils
Vitamin Cobalamine DNA synthesis, red blood cell Fortified Meat, fish,
formation, and neurological function. cereals poultry,
B12 It plays a critical role in maintaining dairy
nerve cells' health and preventing a products
type of anemia called megaloblastic
anemia
Vitamin Cholecalcifero Essential for calcium absorption, Sunlight (UV Fatty fish
bone health, and immune function. It exposure), (salmon,
D helps regulate calcium and fortified tuna,
phosphorus levels in the blood and mackerel),
supports the growth and egg yolks,
maintenance of strong bones and dairy
teeth. products