ATKT exam (Academic Year 2022-2023)

B. Pharm. (Pharmaceutics I) Sem II (Choice based R2019)

QUESTION BANK

1 In liquid dosage form which of the following dosages forms is used for oral
administration.
a Elixirs
b Liniments
c Lotion
d Enema
2 The ____________ was enacted as the nation’s first minimum standard of
educational qualification for pharmacy practice.
a Pharmacy Act 1948
b Drugs and Cosmetics Act 1940 (1945)
c DPCO Act
d Pharmacy Practice regulation
3 Use of formulations made up of numerous plants referred as………..
a Galenicals
b Parenteral
c Plant Vehicles
d Generics
4 Using Dilling's rule, Calculate the dose for a 2 years old child. The adult dose is
500 mg.
a 50 mg
b 80 mg
c 120 mg
d 90 mg
5 Which one is nonnutritive or low-calorie sweetening agents used as additive in
liquid dosage form?
a Aspartame
b Dextrose
c Glucose
d Lactose
6 One fluid ounce is equal to
a 29.57 ml
b 30.47 ml
c 27.67 ml
d 28.77 ml
7 Which type of powder particles pass through a No. 60 sieve (0.25 mm) and not
more than 40% pass through a No. 100 sieve.
a Very Coarse powders
b Coarse powders
b Moderately coarse powders
d Fine powders
8 How many grams of dextrose required to prepare 3000 ml of 5%w/v solution
a 150 gms
b 200 gms
c 250gms
d 300grms
9 Throat paints are ………. liquid preparations.
a Viscous
b Non viscous
c Solid
d Gas
10 Syrup IP contains....%w/w of sugar
a 66.7
b 16.6
c 60.5
d 56.6
11 Hard cake formation is characteristic feature of _______ suspension.
a Flocculated
b Thixotropic
c Structured
d De- flocculated
12 The Proportion of Oil : Water: Gum for preparing primary emulsion of mineral oil
by dry gum method is ____
a 03:02:01
b 02:02:01
c 01:01:01
d 02:01:02
13 Double decomposition is an example of _____________ incompatibility.
a Chemical
b Physical
c Therapeutic
d Biological
14 Which form of cocoa butter is considered to be stable for suppository?
a Alpha Crystal
b Gamma Crystals
c Delta Crystals
d Beta Crystal
15 ________ is a remedy to overcome the incompatibility between oil and water.
a Addition of sweetner
b Addition of surfactant
c Addition of preservative
d Mixing of two phases by stirring
16 __________ measures the time required by suppository to soften under pressures
similar to those found in the rectum in the presence of water at 37◦C.
a Solidification test
b Disintegration test
c Liquefaction test
d Dissolution test
17 Polyethylene glycol are also known as ______________.
a Oleaginous
b Macrogol
c Paraffin
d Lanolin
18 Which base is likely to be the most occlusive on the skin?
a A hydrocarbon base
b An absorption base
c An emulsion base
d A water-soluble base
19 _________is a method of ointment preparation, where mixture of high and low
melting point waxes are used?
a Levigation
b Fusion
c Mixing
d Chemical
20 In the preparation of cold creams, which types of bases are used generally?
a Absorption bases
b Water removable bases
c Hydrocarbon bases
d Gel base
21 Young's rule for calculating approximate child's dose is given as _________

a Dose of Child = Adult dose×(age/(age+12))

b Dose of Child = Age (in months) x 150 /Adult Dose
c Dose of Child = Adult dose×age/(age+20))
d Dose of Child = (Age (in months) x Adult Dose ) /20
22 Capsules in which powders are enclosed are made up of …..
a Gelatin
b Rice flour
c Fructose
d Dextrose
23 The part of the prescription called inscription contains
a Name and quantity of ingredients
b Direction to the patient
c Direction to the patient’s relatives
d Patient information
24 The Chairman of the first edition of IP was…..
a Dr. B.N. Ghosh
 b Dr. B. Mukherjee
c Dr. Nityanand
d Mr. PrasanaTotta
25 What is the ideal particle size for topical powders
a 50 to 100 micron
b 150 to 250 micron
c 250 to 500 micron
d Above 1000 micron
26 Advantage of liquid dosage form over the powders
a bioavailability is less
b easy to swallow
c more bulky
d easy to handle
27 One minim is equal to
a 0.6ml
b 0.06ml
b 0.006ml
d 0.0006ml
28 In heat method of preparing effervescent granules to make damp mass _______
releases 1 molecules of water of crystallization.
a citric acid
b tartric acid
c sodium bicarbonate
d sucrose
29 Douches are meant for application in……………
a Vaginal cavity
b Rectal cavity
c Buccal cavity
d Nasal cavity
30 ........is applied with camel hair brush
a Throat paint
b Mouthwash
c Gargle
d Liniment
31 An assembly is used in which a pair of electrodes connected to an electric bulb is
dipped into an emulsion and the electric bulb glows. Therefore emulsion is
…………..of type.
a o/w
b w/o
c g/o
d o/s
32 Mouthwash is required in ________ condition.
a Halitosis
 b Indigestion
c Yawning
d Hirsutism
33 One of the following is disadvantage of cocoa butter suppository base

a Solid at room temperature but melts in body

b Polymorphism
c Miscibility with many ingredients
d Blandness
44 Interaction between two or more substances which may lead to change in color,
odor, taste, viscosity and morphology is termed as _________.

a Biological incompatibility
b Physical incompatibility
c Therapeutic incompatibility
d Chemical incompatibility
35 Phase inversion is observed when emulsion prepared by using soaps of
monovalent cation is mixed with polyvalent cations.This is example of
__________ incompatibility.
a Chemical
b Physical
c Therapeutic
d Biological
36 Witepsol is classified as which type of suppository base?
a Glycero-Gelatin base
b Synthetic base
c Cocoa butter base
d Macrogol base
37 Which of the following are used as aid for handling of diagnostic equipments like
catheters and rectal thermometers?
a Medicated jellies
b Lubricating jellies
c Miscellaneous jellies
d Flavored jellies
38 __________ are semisolid preparations for external application that differ from
similar products in containing a high proportion of finely powdered medicaments.

a Ointment
b Paste
c Gel
d Cream
39 Which base should be selected when water washability is the key requirement?
a A hydrocarbon base
b An absorption base
c An emulsion base
d A water-soluble base
40 Water number means __________________
a Maximum amount of water that can be added to 100 g of a base at given
temperature
b Minimum amount of water that can be added to 20 g of a base at given
temperature
c Minimum amount of water that can be added to 5 g of a base at given temperature
d Minimum amount of water that can be added to 40 g of a base at given
temperature
41 ___________ are sweet, viscous liquid dosage form of medicaments meant for
cough relief
a Linctus
b Lozenges
c Inhalations
d Tablets
42 Who organizes the Indian Pharmaceutical Congress every year?
a Indian Pharmaceutical Association
b Indian Pharmaceutical Congress
c Indian Pharmaceutical Congress Association
d Indian Pharmacy Graduates Association
43 Using Clark's formula, calculate the dose for a child weighing 20 lb. The adult
dose is 300 mg.
a 40 mg
b 110 mg
c 200 mg
d 35 mg
44 __________ are solid dosage form of medicament enclosed in rice flour waffers.
a Cachets
b Powders
c lozenges
d Tablets
45 Which powders is meant for internal/oral use
a Electrolyte powder
b Talcum powder
c Snuffs
d Dusting powder
46 Which solvent have sweet taste used in formulation of liquid dosage forms
a Propylene glycol
b Glycerine
 c Polyethylene glycol
d Polysorbate 80
47 _____________ are sterile, used in body cavities and major wounds in healing.
a Non-medicated powders
b Medicated dusting powders
b Surgical dusting powders
d Natural dusting powders
48 Calculate the quantity of dextrose required to prepare 200 mL of a 5% w/v
solution.
a 5 grams
b 10 grams
c 5 mg
d 100 grams
49 _____ is a hydroalcoholic preparation.
a Elixir
b syrup
c suspension
d emulsion
50 Which of the following monophasic liquid formulation is classified as a solution
to be used in oral cavity?
a Gargle
b douches
c eardrop
d nasal drop
51 The role of emuslifying agent is __________.
a Decrease surface area in emulsion
b Improves the medication taste
c Increase the size of globules
d Reduce the interfacial tension between miscible phases
52 Calamine Lotion B.P. is an example of ___________.
a Suspension containing indifussible solids
b Mixture Containing precipitate forming Liquid
c Suspension produced by chemical reaction
d Dispersion of oils in inhalations
53 Urethral suppositories also called as _________
a Pessaries
b Bougies
c Enema
d Douches
54 Suppositories can be prepared by _________.
a Precipitation method
b Redispersion Method
c Maceration method
d Compression moulding
55 When water is added to tincture containing resinous matter, resin agglomerates are
formed. This is example of __________ incompatibility.
a Chemical
b Physical
c Therapeutic
d Biological
56 Displacement values calculation ensures ________.
a Correct amount of base
b Correct amount of drug
c Formation of stable suppositories
d Formation of easily mouldable suppositories.
57 ____________ is an example of gelling agent.
a Pectin
b Propylene glycol
c Sorbitol
d Liquid Paraffin
58 When base is soft and medicament is insoluble in base, which method is used to
prepare ointment?
a Fusion method
b Emulsification method
c Trituraton method
d Chemical reaction method
59 Wool fat is also called as _______
a Anhydrous lanolin
b Lanolin
c Petrolatum
d Vaseline
60 Which among the following ointment is prepared by chemical reaction?
a Non-staining Iodine ointment BPC 1968
b Simple ointment B.P.
c Salicylic acid ointment B.P.
d Whitfield's ointment

Descriptive Questions
1. Describe in detail excipients used in formulation of liquid dosage forms.

2. Give advantages and disadvantages of suppositories as a dosage form.

3. Explain ideal properties of suppository bases

4. Discuss in detail raw materials and labeling condition required in formulation of
oral suspension.

5. What are pharmaceutical incompatibilities? Give its types and explain physical
incompatibility with suitable example
 6. Write a note on water soluble bases used in ointment.
7. What is a cream? Differentiate between water in oil and oil in water type of
cream

8. Define Prescription. Discuss in detail different parts of prescription

9. What is pharmacopoeia? Give an account of Indian Pharmacopoeia
10. Find out how many ml of 70%, 40% and 30% of alcohol should be mixed to get
55% v/v 1200ml of alcohol. Add an account on the Apothecaries system.

11. Enlist different methods for mixing of powders? Elaborate on geometric dilution
method.

12. State the merits and demerits of powder dosage form. Elaborate on bulk powders
for internal use.
13. Write a note on Mouthwash
14. Describe different techniques used to identify type of emulsion
15. Discuss the excipients, labeling condition and packaging aspects of oral emulsion.
16. Define displacement value. Calculate the formula for 10 bismuth subgallate
Suppositories each containing 300mg of bismuth subgallate. Given:
Displacement value of Bismuth subgallate is 3.
17. Give definition for pharmaceutical incompatibilities, mention its types and
explain immiscibility as an example of physical incompatibility.
18. Give an account of hydrocarbon bases used in the preparation of ointment
19. Classify semisolid dosage form. Give the advantages and disadvantages of
semisolid dosage form.
20.
21. Define Elixirs, liniments, lozenges, suppositories, throat paint and cachets
22. Define Prescription and discuss in detail handling of Prescriptions.
How
23. many grams of 20% zinc oxide ointment, 10% zinc oxide ointment and 5% zinc
oxide ointment be mixed to get 500 grams of 15% zinc oxide ointment. What is the
Imperial and Metric system?

24. Describe in detail the role of wetting agents, buffers, density modifiers and
preservatives in liquid dosage form as additives with examples
25. Write a note on Nasal drops
26. Give the ideal properties of suspension. State the advantages and disadvantages of
suspension dosage form
27. Write a note on theobroma oil as a suppository base
28.
What are pharmaceutical incompatibilities? Mention its types and explain
Chemical incompatibility with suitable example.

29. Define Ointment. Mention the types and ideal properties of ointment bases
30. What is a gel? Write a note of different types of gel.
31. Discuss different career options available in the Pharmacy Profession
32. Define Dosage form and classify various dosage forms with examples
33. What are the advantages and Disadvantages of liquid dosage form? Add a note on
vehicles
34. Find out how many ml of 60%, 30% and 20% of alcohol should be mixed to get
1400ml of 45% v/v alcohol. Give ideal properties of additives used in liquid dosage
 form
35. Short note on gargle.
36. Enlist the methods of preparation of suspension. Describe any one method