Sadiq Noor Khan, PhD

Born April 15, 1979 Karak (KP), Pakistan.

Permanent Address: Vill and P/O Bogara Tehsil Takhti Nasrati Distt Karak.
Google Scholar: https://scholar.google.com/citations?user=bs9twMoAAAAJ&hl=en
Cell +923465135580
Email: [email protected]
Email: [email protected]

Field of Specialization,
Project planning and management, curriculum designing of BS, MPhil and PhD MLT
Research Interest: Molecular epidemiology, clinical diagnosis of different diseases

Present Position
Chairman-Department of Medical Lab Technology, The University of Haripur. July 28, 2021 to date.
Head: Department of Medical Lab Technology, The University of Haripur, Feb 2017 to January 2020.
Convener: Board of Studies, Department of Medical Lab Technology, July 28, 2021 to date.
Convener: Board of Studies, Doctor of Pharmacy, August 2022 to date.
Convener: Board of Studies, Nursing program, November 2022 to date.
Convener: Graduate Research Committee MLT, July 28, 2021 to date.
Convener: University of Haripur Medical Committee February 2021 to date.
Member: Syndicate (elected), The University of Haripur July 2022 to date.
Member: Academic Council, The University of Haripur
Member: ASRB, The University of Haripur
Member: Board of Faculty, Faculty of Biological and Biomedical Sciences, UoH
Member: Board of Studies MLT, Kohat University of Science and Technology
Member: Board of Studies MLT, Shifa Tameer Millat University, Islamabad
Member: Board of Studies MLT, Rifah International University, Malakand Campus
Member: Board of Studies MLT, Women University Swabi, September 2023 to date
Member: Need Assessment Committee, Faculty of Biological and Biomedical Science Aug 2023 to date
Member: Need Assessment Committee, Faculty of Physical and Applied Science August 2023 to date

Key Administrative and Academic Achievements

Chairman-Department of Medical Lab Technology, The University of Haripur. July 28, 2021 to date.
Head: Department of Medical Lab Technology, The University of Haripur, Feb 2017 to January 2020.
Successful launching of following programs
1. MPhil in Medical Lab Sciences
2. PhD in Medical Lab Sciences
3. BS Radiology Technology
4. BS Anesthesia Technology
5. BS Surgical Technology
6. BS Dental Technology
7. BS Nursing
8. Doctor of Physical Therapy (DPT)
Teaching of Courses at Graduate Level (From 2012 to date)
1. Basic Molecular Biology
2. Molecular Pathology
3. Advances in Immunology
4. Molecular Epidemiology
5. Research Methodology
Teaching of Courses at undergraduate Level (From 2012 to date)
1. Biochemistry I
2. Biochemistry II
3. Chemical Pathology
4. Clinical Hematology
5. Clinical Immunology and serology
6. Fundamental of Clinical Lab

Peer Reviewed Publications:

Total Publications: 37; Cumulative Impact Factor: >100
Publications in Impact Factor Journals: 28
Research, Mentorship and Academics Experience: >11 years
PhD Students Mentored 01: Degree awarded; 01
PhD Students Mentored (In Progress): 04 as supervisor
MPhil Students Mentored (Degree awarded): 25 (16 as supervisor and 09 as Co-supervisor)
Researchers Mentored as PI in projects with external grants: 01
External Research Grants National (Completed):04
External Research Grants National (in progress): 01

Education
Ph.D: Biochemistry, PMAS Arid Agriculture University, Rawalpindi
Research completed at Research Center Borstel Germany, 2012.
Title: Molecular Characterization of some multidrug resistant genes of Mycobacterium tuberculosis
isolates of Pakistan
M. Phil: Biochemistry, PMAS Arid Agriculture University, Rawalpindi, 2008
Title: PCR Based screening of mutations in Neurofibromatosis type 1 (NF1) gene in Pakistani
Population.
M. Sc: Biochemistry, PMAS Arid Agriculture University, Rawalpindi. 2006.
B. Sc: Medical Lab Technology, University of Punjab. 2003.
F. Sc: Medical Lab Technology, CMLT, NIH Islamabad. 2001

Awards and Recognitions

1. Best Teacher Award (The University of Haripur), 2022
2. HEC Indigenous Scholarship (MPhil leading to PhD) 2007-2012
3. International Research Support Initiative Program – HEC scholarship for Research Center Borstel
Germany (2011)
4. Approved PhD Supervisor by HEC
Principal Investigator of External Research Grants (National)
1. Molecular Characterization and mutational analysis of drug resistant Mycobacterium tuberculosis
isolates from Khyber Pakhtunkhwa (HEC NRPU (Y2017), PKR 3.3 Millions Completed
2. Epidemiological and mutational analysis of mitochondrial tRNA gene in myoclonal epileptic patients
from Khyber Pakhtunkhwa HRI NIH 2022, PKR 2.2 Million In Progress
3. Antibacterial Activity Of Medicinal Plant Extracts Against Mycobacterium Tuberculosis funded by
Higher Education Commission, an amount of 0.5 Million (Completed in Y2013)

Co-Principal Investigator of External Research Grants (National)

1. Epidemiological and mutational analysis of mitochondrial tRNA gene in myoclonal epileptic
patients from Khyber Pakhtunkhwa (SRG 0.5 Million) Completed in Y2022
2. Anti-tumor activity of isolated phytochemicals from the flowers of Taraxacum officinales invivo
(SRG 0.5 Million) Completed in Y2015
3. Isolation and molecular characterization of drug resistant Pseudomonas aeruginosa strain from
hospitalized patients (SRG 0.5 Million) Completed in Y2019

PhD students Mentored

1. Abdul Jabbar: Molecular characterization and mutational analysis of drug resistant Mycobacterium
tuberculosis isolates in Khyber Pakhtunkhwa. 2020
2. Awal Mir: Human epigenetic enzymes as novel therapeutic target in beta Thalassemia major patients
(In progress)
3. Nadeem Sharif: Genotypic, Phenotypic and clinical validation of different Diagnostic tools in
Extrapulmonary tuberculosis patients from Punjab (In progress)

M. Phil students Mentored as Supervisor

1. Hadia Misbah: Evaluation of aberrant Myeloid marker expression in childhood acute lymphoblastic
leukemia. 2020
2. Awal Mir: Incidence of Beta thalassemia trait in polycythemia. 2020
3. Anees Muhammad: Molecular Characterization of multidrug resistant genes of Mycobacterium
tuberculosis isolates from Khyber Pakhtunkhwa. 2020
4. Ikram Ullah: Characterization of some multi and extensive drug resistant genes of Mycobacterium
tuberculosis isolates from Khyber Pakhtunkhwa. 2020
5. Shehryar Ahmad: Association of CYP2D6 Polymorphism with different types of leukemia. 2021
6. Waseem Iqbal: Molecular epidemiology of HCV and its response to direct acting drugs. 2021
7. Naeem Ullah: Development of A Real-Time Multiplex PCR Assay for Detection of Common Mpl
Mutations in Myeloprolifirative Neoplasms (MPNS). 2021
8. Shaukat Ali: Whole Genome Sequencing of MTB isolates from Khyber Pakhtunkhwa. 2021
9. Waqar Saeed: Establishment of Real-Time Quantitative PCR Assay for The Detection of CALR
Mutations In Myeloproliferative Neoplasms (MPNS). 2021
10. M. Riaz Khan: Mutational Analysis Of Mitochondrial tRNA Proline (MT-TP) Gene In Myoclonal
Epileptic Patients From North Waziristan. 2021
11. Azhar Nazir: Association of ACE1 polymorphism with severity of COVID-19 infection in Pakistani
population. 2022
12. Saddam Ahmed: Association of genetic factor ACE2 with severity of COVID-19. 2022
13. Noor Ullah: Molecular characterization of mitochondrial Trna proline in myoclonol epileptic
patients from district Bajawar. 2022
14. Wali Ur Rehman: Molecular characterization of SCL1A gene in epileptic patients from Peshawar
KP. 2022
15. Fawad Ahmad: Spectrum of pathogen causing secondary infection in cutaneous Lieshmaniasis in
Khyber Pakhtunkhwa. 2022
16. Tahira Sher Afgan: Mapping Shared And Divergent Genetic Architecture Of Infectious Diseases
(Typhoid, Tuberculosis And Cholera): An Integrated Approach To Predict Genetic Risk Factors In
Tehsil Haripur. 2023

M. Phil (Co-Supervised):
Shah Hussain 2016, Sami Ullah 2016, Rabea Basri 2023, Wahid Ullah 2022, Nouman Aslam 2023,
Asma Naeem 2023, Sohail Sajid 2023, Faisal Khan 2023, Ehthisham Ul Haq 2023,

BS (Hon) (Supervised): 30

Publications in W Category Journals

1. Khan, S. N., S. Neimann, M. Gulfraz, M. Qayyum, S. Siddiqi, Z. S. Mirza, S. Tahsin, M. Ebrahimi-
Rad and A. Khanum 2013. Molecular Characterization of Multidrug-Resistant Isolates of
Mycobacterium tuberculosis from Patients in Punjab, Pakistan. Pak. J. Zool., vol. 45(1), pp. 93-100.
(IF: 0.266)
2. Jamila. N., SN. Khan and N. Khan 2014. Phytochemicals from the Bark of Garcinia hombroniana
Pierre and Their Biological Activities. Rec. Nat. Prod. 8: 312-316 (Impact Factor: 1.17).
3. Jamila. N., S. N. Khan and N. Khan. 2014. Complete NMR assignments of bioactive rotameric (3→8)
biflavonoids from the bark of Garcinia hombroniana. Megnetic Resonance In Chemistry 52:345–352
IF: 1.179
4. Jamila. N., Khairuddean. M. H. Osman, N. N. Syazni, N. M. Kamal, N. S. Yaacob, S.N. Khan and N.
Khan. 2014. Cytotoxic benzophenone and triterpene from Garcinia hombroniana. Bioorganic
Chemistry, 54: 60-67 (IF 2.152).
5. Nargis Jamila, Naeem Khan, Imran Khan, Amir Atlas Khan & Sadiq Noor Khan 2016. A bioactive
cycloartane triterpene from Garcinia hombroniana. Natural Product Research, 30: 1388–1397. (IF:
1.828)
6. Jamila N, Yeong KK, Murugaiyah V, Atlas A, Khan I, Khan N, Khan SN, Khairuddean M and Osman
H. (2015). Molecular docking studies and in vitro cholinesterase enzymes inhibitory activities of
chemical constituents of Garcinia hombroniana. Nat. Prod Res 29(1):86-90. doi:
10.1080/14786419.2014.952228 (Impact Factor: 1.057).
7. Nargis Jamila, Naeem Khan, Amir Atlas Khan, Sadiq Noor Khan and Kyong Su Kim. 2016.
Phytochemical Analysis, Antioxidant, Anti-Hyperglycemic and Antituberculosis Activities of
Phylogenetically Related Garcinia mangostana (Mangosteen) and Garcinia hombroniana (Seashore
Mangosteen). J.Chem.Soc.Pak., 38, 06. IF:0.35
8. Hazir Rahman, Shakir Ullah Khan, Muhamamd Amjad Khan, Muhammad Qasim, Abdul Jabbar,
Sadiq Noor Khan, Zakir Khan, Taj Ali Khan, Mubbashir Hussain, Noor Muhammad, Nawab Ali.
2017. Molecular detection of rifampicin resistance by GeneXpert®assay among treated and untreated
pulmonary tuberculosis patients from Khyber Pakhtunkhwa, Pakistan. J. Global Antimic Resist. 9:
118-120. IF: 2.02
9. Nargis Jamila, Naeem Khan, In Min Hwang, Ji Yeon Choi, Eun Yeong Nho, Sadiq Noor Khan, Amir
Atlas, Kyong Su Kim. 2019. Determination of macro, micro, trace essential, and toxic elements in
Garcinia cambogia fruit and its anti‐obesity commercial products. Journal of the science of food and
agriculture 99:2455-2462 IF: 2.614
10. Abdul Jabbar, Jody E. Phelan, Paola Florez de Sessions, Taj Ali Khan, Hazir Rahman, Sadiq Noor
Khan, Daire M. Cantillon, Leticia Muraro Wildner, Sajid Ali, Susana Campino, Simon J. Waddell &
Taane G. Clark. 2019. Whole genome sequencing of drug resistant Mycobacterium tuberculosis
isolates from a high burden tuberculosis region of north West Pakistan. Scientific Report. 9:1-9
.https://doi.org/10.1038/s41598-019-51562-6 I.F 3.998
11. Nargis Jamila, Naeem Khan, In Min Hwang, Sadiq Noor Khan and Amir Atlas. 2020. Elemental
Analysis and Bioactivities of Echinops Echinatus Roxb. (Globe Thistle) Via Spectroscopic
Techniques. Pak. J. Bot. 52: 121-128 IF: 0.972
12. Nargis Jamila, Naeem Khan, In Min Hwang, Malka Saba, Faryal Khan, Farhat Amin, Sadiq Noor
Khan, Amir Atlas, Fatima Javed, Aaliya Minhaz, Faheem Ullah. 2020. Characterization of natural
gums via elemental and chemometric analyses, synthesis of silver nanoparticles, and biological and
catalytic applications. International Journal of Biological Macromolecules. 147:853-
866.https://doi.org/10.1016/j.ijbiomac.2019.09.245 IF: 6.953
13. Nargis Jamila, Naeem Khan, In Min Hwang, Eun Yeong Nho, Ji Yeon Choi ,Amir Atlas, Sadiq Noor
Khan, Farhat Amin, Fatima Javed and Kyong Su Kim. 2020. Application of Phytochemical and
Elemental Profiling, Chemometric Multivariate Analyses, and Biological Activities for
Characterization and Discrimination of Fruits of Four Garcinia Species. Analytical Letters 53:122-139
https://doi.org/10.1080/00032719.2019.1640244. I.F 2.329
14. Anees Muhammad, Sadiq Noor Khan, Nasir Ali, Mujeeb Ur Rehman, Ihsan Ali 2020. Prevalence and
antibiotic susceptibility pattern of uropathogens in outpatients at a tertiary care hospital. New
Microbes and New Infections. DOI: https://doi.org/10.1016/j.nmni.2020.100716. IF 0.599
15. Aaliya Minhaz, Naeem Khan, Nargis Jamila, Fatima Javed, Muhammad Imran, Shaukat Shujah, Sadiq
Noor Khan, Amir Atlas, Muhammad Raza Shah. 2020. Schiff base stabilized silver nanoparticles as
potential sensor for Hg (II) detection, and anticancer and antibacterial agent. Arabian Journal of
Chemistry.13: 8898-8908 IF: 5.165
16. Nargis Jamila, Naeem Khan, Amina Bibi, Adnan Haider, Sadiq Noor Khan, Amir Atlas, Umar Nishan,
Aaliya Minhaz, Fatima Javed, Ahtaram Bibi. 2020. Piper longum catkin extract mediated synthesis of
Ag, Cu, and Ni nanoparticles and their applications as biological and environmental remediation
agents. Arabian Journal of Chemistry. 13: 6425-6436 IF: 5.165
17. Sajid Ali, Muhammad Tahir Khan, Anwar Sheed Khan , Noor Mohammad, Muhammad Mumtaz
Khan, Sajjad Ahmad, Sadiq Noor, Abdul Jabbar, Cantillon Daire and Fariha Hassan. 2020. Prevalence
of Multi-Drug Resistant Mycobacterium Tuberculosis in Khyber Pakhtunkhwa – A High Tuberculosis
Endemic Area of Pakistan. Polish Journal of Microbiology. 69: 33–137. IF 1.28
18. Nargis Jamila, Naeem Khan, Nousheen Bibi, Muhammad Waqas, Sadiq Noor Khan, Amir Atlas,
Farhat Amin, Faryal Khan, Malka Saba. 2021. Hg (II) sensing, catalytic, antioxidant, antimicrobial,
and anticancer potential of Garcinia mangostana and α-mangostin mediated silver nanoparticles.
Chemosphere. 272:129794 IF: 8.943
19. Naeem Khan, Nargis Jamila, Farhat Amin, Rehana Masood, Amir Atlas, Wajheeba Khan, Noor Ul
Ain, Sadiq Noor Khan. 2021. Quantification of macro, micro and trace elements, and antimicrobial
activity of medicinal herbs and their products. Arabian Journal of Chemistry. 14 : 103055 IF: 6.212
20. Abdul Jabbar, Taj Ali Khan, Hazir Rehman, Anwar Sheed Khan, Sajjad Ahmad, Sadiq Noor Khan.
2021. Burden of Drug resistant Tuberculosis in newly diagnosed Tuberculosis patients of Khyber
Pakhtunkhwa, Pakistan. The Journal of the Pakistan Medical Association. 71: 912-915 IF: 1.002
21. Yassir A Shuaib, Christian Utpatel, Thomas A Kohl, Ivan Barilar, Margo Diricks, Nadia Ashraf,
Lothar H Wieler, Glennah Kerubo, Eyob A Mesfin, Awa Ba Diallo, Sahal Al-Hajoj, Perpetua
Ndung’u, Margaret M Fitzgibbon, Farzam Vaziri, Vitali Sintchenko, Elena Martinez, Sofia O Viegas,
Yang Zhou, Aya Azmy, Khaled Al-Amry, Sylvain Godreuil, Mandira Varma-Basil, Anshika Narang,
Solomon Ali, Patrick Beckert, Viola Dreyer, Mwila Kabwe, Matthew Bates, Michael Hoelscher,
Andrea Rachow, Andrea Gori, Emmanuel M Tekwu, Larissa K Sidze, Assam A Jean-Paul, Veronique
P Beng, Francine Ntoumi, Matthias Frank, Aissatou Gaye Diallo, Souleymane Mboup, Belay
Tessema, Dereje Beyene, Sadiq N Khan, Roland Diel, Philip Supply, Florian P Maurer, Harald
Hoffmann, Stefan Niemann, Matthias Merker. 2022. Origin and Global Expansion of Mycobacterium
tuberculosis Complex Lineage 3. Genes. 13:990 IF: 4.141
22. Rabeea Siddique, Syed Ainul Abideen, Ghulam Nabi, Faryal Mehwish Awan, Sadiq Noor Khan,
Fawad Ullah, Suliman Khan, Mengzhou Xue. 2022. Fibroblast growth factor 2 is a druggable target
against glioblastoma: A computational investigation. Frontiers in Chemistry. 10: 1071929 IF: 5.545
23. Naila Qamar, Gul Rukh, Sadiq N Khan. 2022. Vaccines for Covid‐19: An insight on their effectiveness
and adverse effects. Journal of Medical Virology. 94: 3554-3560 IF: 12.7
24. Naeem Ullah, Sadiq Noor Khan, Muhammad Umair, Aamir Ali Khan, Xinhui Liu, Aamer Ali Khattak,
Yasar Mehmood Yousafzai. 2022. Development of a Real-Time qPCR Assay for Detection of
Common MPL Mutations in Myeloproliferative Neoplasms (MPNS). Applied Biochemistry and
Biotechnology.194: 5907–5917. IF: 3.09
25. Hassan Ayaz, Nouman Aslam, Faryal Mehwish Awan, Rabea Basri, Bisma Rauff, Badr Alzahrani,
Muhammad Arif, Aqsa Ikram, Ayesha Obaid, Anam Naz, Sadiq Noor Khan, Burton B Yang, Azhar
Nazir. 2023. Mapping CircRNA–miRNA–mRNA regulatory axis identifies hsa_circ_0080942 and
hsa_circ_0080135 as a potential theranostic agents for SARS-CoV-2 infection. Plos one. 18: e0283589
IF: 3.75
26. Rabea Basri, Faryal Mehwish Awan, Burton B Yang, Usman Ayub Awan, Ayesha Obaid, Anam Naz,
Aqsa Ikram, Suliman Khan, Ijaz ul Haq, Sadiq Noor Khan, Muslim Bin Aqeel. 2023. Brain-protective
mechanisms of autophagy associated circRNAs: Kick starting self-cleaning mode in brain cells via
circRNAs as a potential therapeutic approach for neurodegenerative diseases. Frontiers in Molecular
Neuroscience. 15:1078441. IF: 6.26
27. Muhammad Ilyas, Dorothea Holzwarth, Rafaqat Ishaq, Yasir Ali, Umme Habiba, Asad Mehmood
Raja, Sadia Saeed, Uzma Abdullah, Sadiq Noor Khan, Ata Ullah, Ghazala Kaukab Raja, Shahid
Mehmood Baig, Walid Fazeli, Wolfram S Kunz, Pakeeza Arzoo Shaiq. 2023. Whole-Exome
sequencing identifies GYS2 biallelic variants in individuals with suspected epilepsy. Seizure:
European Journal of Epilepsy. https://doi.org/10.1016/j.seizure.2023.07.020. IF: 3.0

Publications in HEC Recognized Journals

1. Ashraf, S., M. A. N. Saqib, M. Z. Sharif, A. A. Khattak, S. N. Khan, S. A. Malik, S. Tahseen, A.

Khanum. 2014. Evaluation of diagnostic potential of Rv3803c and Rv2626c recombinant antigens in
TB endemic country Pakistan. J. Immunoassay and Immunochemistry. 35:120–129.
2. Khan, N., S. T. Hussain, A. Saboor, N. Jamila, S. N. Khan and K. Su. Kim 2013. Chemical
Investigation of the Drinking Water Sources from Mardan, Khyber Pakhtunkhwa, Pakistan. World
Appl. Sci. J. 27 (1): 112-122.
3. Javed F, S. Manzoor, AA Khattak, N. Aurangzeb, SN Khan, D. Habib, and A. Saleem 2015. NS3-4A
and NS4A proteins of hepatitis C virus regulate the apoptotic proteins expression in Huh-7 cells. Int.
J. Biosci. 7(5): 9-15.
4. Bukhari N, A. Saleem, A. Jabbar. SN Khan et al. 2016. Frequency of typhoid fever and its association
with seasonal variations in Taxila, Pakistan. Asian Pacific J. Trop. Disease. 6 (8), 608-610
5. Sami Ullah, Shah Hussain, Sadiq Noor Khan, Mohammad Khurram, Iqbal Khan, Murad Ali Khan.
2017. The Medicinal Plants in the Control of Tuberculosis: Laboratory Study on Medicinal Plants
from the Northern Area of Pakistan. Int J Mycobacteriol 2017;6:102-5
6. Amir Atlas, Nargis Jamila, Sadiq Noor Khan, Hameed Ur Rehman, Jabar Zaman Khan Khattak,
Muhammad Arshad Malik, Matiullah, Ajmal Shah, 2019. Screening of GHRHR and Npr2 genes as a
genetic contributors of dwarfism in familial dwarfism of Khyber Pakhtunkhwa, Pakistan. Int. J. Biosci
14: 263-270.
Workshops/Seminars Organized:
1. 1st Hands on Training workshop on Bioinformatics tools for Clinical Research: From data Analysis to
Translational Insights, 2023.
2. Qualitative and quantitative research and Proposal Writing The University of Haripur, 2019.
3. Clinical Laboratory Professional Week The University of Haripur April May, 2019
4. Pink ribbon youth awareness Drive, The University of Haripur March 07, 2019
5. 1st International Workshop on Nano Science and Technology 2018, October 30-31, 2018 at The
University of Haripur
6. Biosafety Awareness workshop in collaboration with PBSA and Fogarty International Centre NIH
USA on October 25, 2018 at The University of Haripur.
7. Exploring Bacteriophage for Phage Therapy University of Haripur May 4-5, 2017
8. One day awareness seminar on TB University of Haripur March 22, 2017
9. Bioassays for Discovery and Safety Analysis of Bioactive Compound University of Haripur April 10,
2017
7. One Day Seminar on Nanoscience and Nanotechnology University of Haripur March 07, 2017
8. Pink ribbon youth awareness Drive “PINKtober 2016” University of Haripur October 2016
9. Clinical Laboratory Professional Week University of Haripur April 25-28, 2016
10. One day seminar on World TB Day University of Haripur March 30, 2016