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High Yield Drugs

The document outlines various high-yield drugs and their implications for specific patient conditions, including hypertension in pregnancy, gynecomastia, and drug-induced lupus. It details alternative medications for patients with allergies or contraindications, as well as side effects associated with certain drug classes. Additionally, it highlights important considerations for conditions like hemolysis, nephrotoxicity, and prolonged QT syndrome.

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Appu Elias
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28 views2 pages

High Yield Drugs

The document outlines various high-yield drugs and their implications for specific patient conditions, including hypertension in pregnancy, gynecomastia, and drug-induced lupus. It details alternative medications for patients with allergies or contraindications, as well as side effects associated with certain drug classes. Additionally, it highlights important considerations for conditions like hemolysis, nephrotoxicity, and prolonged QT syndrome.

Uploaded by

Appu Elias
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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Dirty Medicine High Yield Drugs

Hypertension in pregnancy: Patient needs NSAID, but has gastric ulcers

- Hydralazine - Celecoxib (COX-2 Inhibitor)

- Methyldopa
Patient has Heparin Induced Thrombocytopenia
- Labetalol
- STOP Heparin
- Nifedipine
- Direct Thrombin Inhibitor (Argatroban)
“Hypertensive Moms Love Nifedipine”

Patient needs Furosemide but has sulfa allergy Gynecomastia

- Ethacrynic Acid (loop diuretic) - Spironolactone (switch to Eplerenone)

- Ketoconazole
Diuretics

- HYPER Calcemia (Thiazides) Drug Induced Lupus (Anti-Histone Ab)

- HYPO Calcemia (Loops) - Hydralazine


o “Loops lose” - Isoniazid
- Worsened Gout/Hyperuricemia (Thiazides) - Procainamide
- Ototoxicity (Loops) - Methyldopa

- Quinidine
Dilated Cardiomyopathy

- Alcohol Ototoxicity
- Doxorubicin/Daunorubicin - Aminoglycoside amiNOglycoside
o Treat with Dexrazoxane - Loop diuretics N = Nephrotoxic
- Cisplatin O = Ototoxic
Orange bodily secretions
- Aspirin (ASA)
- Rifampin (could also be red)
Nephrotoxicity Amphotericin = Amphoterrible
Red Man Syndrome
- Aminoglycoside or Amphlebitis
- Vancomycin
- Amphotericin B
Grey Baby Syndrome

- Chloramphenicol
Agranulocytosis

- Clozapine

- ”Monitor your CBC Clozly”


Cough & Angioedema Cartilage Damage

- ACE Inhibitors (switch to ARBs) - Fluoroquinolones (avoid in children)

- Mechanism: Bradykinin buildup Bone/Teeth Damage

Hemorrhagic Cystitis - Tetracyclines (avoid in children & pregnancy)

- Cyclophosphamide Prolonged QT Syndrome

o Treat with Mesna - Azithromycin, Class IA, IC, & III anti-arrhythmics

o Affects K+ action in cardiac myocytes


Hemolysis in G6P Deficiency

- Quinidine TB Drugs

- TMP-SMX - Rifampin – Orange Secretions

- Sulfonamides - Isoniazid – Neuropathy-B6 deficiency, Drug-SLE, Hemolysis

- Isoniazid - Pyrazinamide – Gout

- Ethambutol – Optic Neuritis

“RIPE ONGO”

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