Introduction to Immunodeficiency Disorders
Introduction to Immunodeficiency Disorders
This module primarily focuses on secondary immunodeficiency disorders, which occur due to external
factors like cancer, AIDS, obesity, alcoholism, smoking, and other lifestyle disorders. Understanding these
conditions is crucial for healthcare professionals, particularly psychologists, as mental health plays a
significant role in both the onset and management of these disorders.
Types of Cancer
Cancer is classified based on the type of cells affected and the organ it originates from. The five main
categories of cancer are:
1. Carcinomas (Most Common - 80-90%)
Originate in the epithelial cells (skin or tissue lining organs).
Examples:
o Breast cancer
o Lung cancer
o Prostate cancer
o Colon cancer
2. Sarcomas
Develop in connective tissues (bones, cartilage, fat, muscles).
Examples:
o Osteosarcoma (bone cancer)
o Liposarcoma (fat tissue cancer)
3. Leukemias (Blood Cancer)
Cancer of the bone marrow, affecting blood cell production.
Leads to excessive production of abnormal white blood cells.
Examples:
o Acute Lymphoblastic Leukemia (ALL)
o Chronic Myeloid Leukemia (CML)
4. Lymphomas
Cancer of the lymphatic system, which helps fight infections.
Examples:
o Hodgkin’s Lymphoma
o Non-Hodgkin’s Lymphoma
5. Brain and Spinal Cord Cancers (CNS Cancers)
Originate in the central nervous system (CNS).
Examples:
o Glioblastoma
o Medulloblastoma
Modes of Transmission
HIV spreads through direct contact with certain bodily fluids of an infected person. The most common
routes include:
Unprotected Sexual Contact (vaginal, anal, or oral sex).
Blood Transmission (sharing needles, contaminated blood transfusions).
Mother-to-Child Transmission (during pregnancy, childbirth, or breastfeeding).
Occupational Exposure (healthcare workers exposed to infected blood).
HIV is NOT transmitted through:
🚫 Casual touch, hugging, or sharing food.
🚫 Mosquito bites or insect stings.
🚫 Sneezing, coughing, or saliva.
Symptoms of AIDS
As HIV progresses to AIDS, the immune system becomes extremely weak, and the body can no longer fight
infections effectively. Common symptoms include:
Severe and persistent fatigue
Rapid weight loss (wasting syndrome)
Recurring fever and night sweats
Chronic diarrhea
Swollen lymph nodes
Skin rashes and sores
Opportunistic infections like tuberculosis, pneumonia, and candidiasis
Neurological symptoms such as memory loss, confusion, and difficulty concentrating
Diagnosis of HIV/AIDS
HIV is diagnosed through blood tests that detect:
✔ HIV Antibodies and Antigens: ELISA and Western Blot tests.
✔ Viral Load Tests: Measure the amount of virus in the blood.
✔ CD4+ Cell Count: Determines the immune system's strength.
Early detection is crucial because treatment with antiretroviral therapy (ART) can slow down the virus’s
progression.
Treatment of HIV/AIDS
There is no cure for HIV/AIDS, but antiretroviral therapy (ART) can effectively control the virus and
enable individuals to live long, healthy lives.
🔹 ART consists of a combination of drugs that suppress HIV replication.
🔹 It helps maintain a high CD4+ count and reduces the risk of opportunistic infections.
🔹 Consistent ART use can make HIV undetectable, significantly lowering transmission risk.
🔹 Proper treatment improves quality of life and life expectancy.
Apart from ART, patients require:
Nutritional support to maintain a healthy immune system.
Treatment for opportunistic infections (antibiotics, antifungal, and antiviral medications).
Vaccination against preventable diseases (e.g., hepatitis, pneumonia).
The modern world has witnessed a sharp increase in lifestyle-related diseases, particularly due to
urbanization, sedentary habits, excessive reliance on technology, unhealthy eating patterns, and high levels
of stress. According to the World Health Organization (WHO), lifestyle disorders are responsible for over
70% of deaths worldwide. These diseases do not spread from person to person, yet they pose a significant
burden on healthcare systems globally.
Lifestyle disorders affect multiple aspects of health, including physical well-being, mental health, social
relationships, and overall quality of life. Many of these conditions are preventable through lifestyle
modifications, early intervention, and behavior changes. The role of psychologists in this domain is critical,
as they assist individuals in understanding, coping with, and modifying behaviors that contribute to these
conditions.
Conclusion
Lifestyle disorders are a growing concern in modern society, affecting both physical and mental health.
These conditions are largely preventable and manageable with the right interventions. Psychologists play a
crucial role in guiding individuals toward positive behavioral changes, helping them develop resilience, and
providing emotional support. By addressing the psychological factors contributing to lifestyle disorders,
individuals can improve their overall well-being and lead healthier, more fulfilling lives.