eT Chargafts rule is 31. (1) Molar amount of guanine is equal to that of adenine 2) A+T/C+ Gis more than unity in bacteria @) Applicable to ssONA (4) A+ G/T + Cis equal to one In eukaryotes, enzyme used for the transcription of tRNA is (1) RNA polymerase - | (2) RNA polymerase - II @) RNA polymerase - Il (4) Both RNA polymerase | & Il SECTION - C Previous Years Questions Ifthe distance between two consecutive base pairs is 0.34 nm and the total number of base pairs of a DNA double helix in a typical mammalian cell is 6.6 x 10° bp, then the length of the DNA is approximately [NEET-2020 (Phase-1)] (1) 2.5 meters (2) 2.2 meters (3) 2.7 meters (4) 2.0 meters Name the enzyme that facilitates opening of DNA helix during transcription. [NEET-2020 (Phase-1)] (1) DNA helicase (2) DNA polymerase (3) RNA polymerase (4) DNA ligase Which of the following statements is correct? INEET-2020 (Phase-1)] (1) Adenine pairs with thymine through one H-bond @) Adenine pairs with thymine through three H- bonds {@) Adenine does not pair with thymine (4) Adenine pairs with thymine through two H- bonds Choose the correct pair from the following INEET-2020 (Phase-1)] (1) Polymerases - Break the DNA into fragments (2) Nucleases - Separate the two strands of DNA (3) Exonucleases - Make cuts at specific positions within DNA (4) Ligases = Join the two DNA molecules 2 10, The first phase of translation is INEET-2020 (Phase-1)] (1) Recognition of DNA molecule (2) Aminoacylation of (RNA (3) Recognition of an anti-codon (4) Binding of mRNA to ribosome ‘The term ‘Nuclein' for the genetic material was used by [NEET-2020 (Phase-2)] (1) Mendel (2) Franklin (3) Meischer (4) Chargaff Which is the basis of genetic mapping of human genome as well as DNA finger printing? [NEET-2020 (Phase-2)] (1) Polymorphism in RNA sequence (2) Polymorphism in DNA sequence @) Single nucleotide polymorphism (4) Polymorphism in hnRNA sequence E. Coli has only 4.6 x 10° base pairs and completes the process of replication within 18 minutes; then the average rate of polymerisation is approximately [NEET-2020 (Phase-2)] (1) 1000 base pairs/second (2) 2000 base pairs/second (3) 3000 base pairs/second (4) 4000 base pairs/second From the following, identify the correct combination of salient features of genetic code [NEET-2019 (Odisha)] (1) Degenerate, Non-overtapping, Non-ambiguous (2) Universal, Non-ambiguous, Overlapping (3) Degenerate, Overiapping, Commaless (4) Universal, Ambiguous, Degenerate Which scientist experimentally proved that DNA is the sole genetic material in bacteriophage? INEET-2019 (Odisha)] (1) Jacob and Monod (2) Beadle and Tautum (3) Meselson and Stahl (4) Hershey and Chase ‘Scanned with CamScannerNn. In the process of transcription in Eukaryotes, the RNA polymerase | transcribes INEET-2019 (Odisha}] (1) Precursor of mRNA, hnRNA (2) mRNA with additional processing, capping and tailing (3) tRNA, 5 sfRNA and snRNAs (4) FRNAs - 28 S, 18 S and 58S .. What initiation and termination factors are involved in transcription in Eukaryotes? INEET-2019 (Odisha)] (1) cand o, respectively 2) cand p, respectively (@) cand B, respectively (4) Bandy, respectively . Match the following RNA polymerases with their transcribed products : (@) RNA polymerase | (©) RNA polymerase I! (i) rRNA (c) RNA polymerase Il! (ii) hnRNA Select the correct option from the following : (1) (2), (OH, (©) 2) @HD, (OH), (Ci) (3) (@H(i), (O}Ci), (CH) (4) (@}-(i), (b){ii), (CC) INEET-2019 (Odisha)} () tRNA . What will be the sequence of mRNA produced by the following stretch of DNA? [NEET-2019 (Odishal] 3 ATGCATGCATGCATG 5’ TEMPLATE STRAND 5’ TACGTACGTACGTAC 3’ CODING STRAND (1) 3 AUGCAUGCAUGCAUG 3° (2) 3’ AUGCAUGCAUGCAUG 5° (3) 5’ UACGUACGUACGUAC 3° (4) 3’ UACGUACGUACGUAC 5° Which of the following nucleic acids is present in ‘an organism having 70 $ ribosomes only? [NEET-2019 (Odisha)] (1) Double stranded circular ONA with histone proteins (2) Single stranded DNA with protein coat (3) Double stranded circular naked DNA (4) Double stranded DNA enclosed in nuclear 18. What map unit (Centimorgan) is adopted in the construction of genetic maps? INEET-2019] (1) A unit of distance between two expressed genes representing 10% cross over (2) A unit of distance between two expressed genes representing 100% cross over @) A unit of distance between genes on chromosomes, representing 1% cross over (4) A unit of distance between genes on chromosomes, representing 50% cross over . Expressed Sequence Tags (ESTs) refers to = [NEET-2019] ry (1) Genes expressed as RNA (2) Polypeptide expression (3) DNA polymorphism (4) Novel DNA sequences 18. Match the following genes of the Lac operon with their respective products (@) igene () Begalactosidase (0) zgene (i) Permease (©) agene (ii) Repressor (@) y gene (v) Transacetylase [NEET-2019] Select the correct option. @o © @ M@ Gi) Qa) 0 @ ag) 7 ™ Ww 4 gi) ™ @ fi) 19. Under which of the following conditions will there be no change in the reading frame of folowing mRNA? S’AACAGCGGUGCUAUUS' [NEET-2019] (1) Insertion of G at 5" position (2) Deletion of G from 5" position (@) Insertion of A and G at 4% and 5" positions respectively (4) Deletion of GGU from 7*, 8% and 9" positions 20. Allof the following are part of an operon except [NEET-2018] (1) An operator (2) Structural genes ‘Scanned with CamScanner21. 2B. 4 3. AGGTATCGCAT is a sequence from the coding strand of a gene. What will be the corresponding sequence of the transcribed mRNA? [NEET-2018] (1) AGGUAUCGCAU (2) USGTUTCGCAT (3) UCCAUAGCGUA (4) ACCUAUGCGAU Select the correct match INEET-2018] (1) Ribozyme ~ Nucleic acid (2) F, x Recessive parent - Dihybrid cross (3) G Mendel = Transformation (4) TH. Morgan ~ Transduction Select the correct match [NEET-2018) (1) Alec Jeffreys = Streptococcus pneumoniae @) Allred Hershey and - TMV Martha Chase @) Francois Jacob and - Lac operon Jacques Monod (4 Matthew Meselson - Pisum sativum and F. Stahl The experimental proof for semiconservative replication of DNA was first shown in a [NEET-2018] (1) Fungus (2) Bacterium @) Vins (4) Plant Ifthere are 999 bases in an RNA that codes for a protein with 333 amino acids, and the base at Position 901 is deleted such that the length of the RNA becomes 998 bases, how many codons will be altered? INEET-2017] a4 Qn @) 33 @) 333 The final proof for DNA as the genetic material came from the experiments of INEET-2017] (1) Grifith (2) Hershey and Chase (3) Avery, McLeod and McCarty (4) Hargobind Khorana 27. 28. 29. 31. 32. 33. ‘The association of histone H1 with a nucleosome indicates: INEET-2017] (1) Transcription is occurring (2) DNA replication is occurring 3) The DNA is condensed into a Chromatin Fibre (4) The DNA double helix is exposed Spliceosomes are not found in cells of {NEET-2017] (1) Plants (2) Fungi 3) Animals (4) Bacteria DNA replication in bacteria occurs [NEET-2017] (1) During S-phase (2) Within nucleolus (3) Prior to fission (4) Just before transcription Which of the following RNAs should be most abundant in animal call? INEET-2017] (1) FRNA (2) FRNA (3) mRNA (4) mERNA During DNA replication, Okazaki fragments are Used to elongate INEET-2017] (1) The leading strand towards replication fork (2) The lagging strand towards replication fork (3) The leading strand away from replication fork (4) The lagging strand away from the replication fork, Taylor conducted the experiments to prove semiconservative mode of chromosome replication on INEET (Phase-2)-2016] (1) Vinca rosea (2) Vicia faba (3) Drosophila melanogaster (4) & colt The equivalent of a structural gene is INEET (Phase-2)-2016] (1) Muton (2) Cistron (3) Operon (4) Recon Which of the following RNAs acts as structural RNA as well as ribozyme in bacteria? INEET (Phase-2)-2016] 2 18S (RNA (4) 58S rRNA (1) 5S rRNA (8) 23 S FRNA ‘Scanned with CamScanner35. 37. 38. 39. 40. DNA-dependent RNA polymerase catalyzes transcription on one strand of the DNA which is called the INEET (Phase-2)-2016] (1) Template strand (2) Coding strand (@) Alpha strand (4) Antistrand Which of the following is required as inducer(s) for the expression of Lac operon? [NEET-2016) (1) Lactose and Galactose (2) Glucose 3) Galactose (4) Lactose Which of the following is not required for any of the techniques of DNA fingerprinting available at present? INEET-2016] (1) DNA-DNA hybridization (2) Polymerase chain reaction ) Zinc finger analysis (4) Restriction enzymes Which one of the following is the start codon? [NEET-2016) (1) UAG (2) AUG (3) UGA (4) UAA Identify the correct order of organisation of genetic material from largest to smallest [Re-AIPMT-2015] (1) Chromosome, genome, nucleotide, gene (2) Chromosome, gene, genome, nucleotide (8) Genome, chromosome, nucleotide, gene (4) Genome, chromosome, gene, nucleotide Satelite DNA is important because it [Re-AIPMT-2015] (1) Code for enzymes needed for DNA replication (2) Codes for proteins needed in cell cycle (3) Shows high degree of polymorphism in population and also the same degree of polymorphism in an individual, which is heritable from parents to children (4) Does not code for proteins and is same in all members of the population a. 42. 43. 45. ee Gene regulation governing lactose operon of E.coli that involves the lac | gene product is [AIPMT-2015] (1) Feedback inhibition because excess of Prgalactosidase can switch off transcription 2) Positive and inducible because it can be induced by lactose (3) Negative and inducible because repressor protein prevents transcription (4) Negative and repressible because repressor protein prevents transcription Which one of the followings is wrongly matched? [AIPMT-2014) (1) Transcription- Writing information from DNA to tRNA (2) Translation-Using information in m-RNA to make protein 3) Repressor protein-Binds to operator to stop enzyme synthesis (4) Operon-Structural genes, operator and promoter Select the correct option [AIPMT-2014] Direction of | Direction of reading RNA synthesis | of the template DNA. strand ()] 5-3" 3-5 (2) 3-5" 5-3 @)} 5-3" 5-3 | axes" <8 Transformation was discovered by [AIPMT-2014] (1) Meselson and Stahl (2) Hershey and Chase @) Grifith (4) Watson and Crick The diagram shows an important concept in the genetic implication of DNA. Fill in the blanks AtoC. Qu AsmRNA-2+ Protein —rewosed by, INEET-2013] (1) Actranslation, B-transcription, C-Erevin Chargaff (2) Actranscription, B-translation, C-Francis Crick (3) A-translation, B-extension, C-Rosalind Franklin (4) Actranscription, B-replication, CJames Watson ‘Scanned with CamScanner