The document provides detailed information on two medications: Cefuroxime, a semisynthetic cephalosporin antibiotic used for bacterial infections, and Ranitidine, an H2 antagonist used to reduce gastric acid secretion. It outlines their mechanisms of action, indications, contraindications, drug interactions, adverse reactions, and nursing responsibilities. Proper administration, monitoring for side effects, and patient education are emphasized for both drugs.
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Drug study
The document provides detailed information on two medications: Cefuroxime, a semisynthetic cephalosporin antibiotic used for bacterial infections, and Ranitidine, an H2 antagonist used to reduce gastric acid secretion. It outlines their mechanisms of action, indications, contraindications, drug interactions, adverse reactions, and nursing responsibilities. Proper administration, monitoring for side effects, and patient education are emphasized for both drugs.
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Drug Data Mechanism Indication Contraindication Drug Adverse Nursing
of action Interaction Reaction Responsibilities
Generic Inhibits Indicated for Allergy to Probenecid: Gastrointestinal: -Ensure proper dosage is Name: bacterial cell bacterial cephalosporins or Increases dyspepsia, calculated based on weight Cefuroxime wall synthesis infections penicillin (cross- cefuroxime levels nausea, vomiting, by binding to contributing to reactivity may by reducing renal and diarrhea. -Explain the purpose of Brand Name: penicillin- systemic occur). excretion. Hepatic: liver cefuroxime and possible Ceftin binding symptoms like enzyme side effects (e.g., nausea, proteins dehydration or Use cautiously in Loop diuretics: elevations in diarrhea, rash). Dosage: (PBPs), gastrointestinal patients with renal Increased risk of some cases. 750mg leading to distress. impairment or colitis. nephrotoxicity. Hypersensitivity: -Ensure the correct route of bacterial cell Rash, itching, administration and monitor Route & lysis and Hepatic dysfunction Aminoglycosides: swelling, difficulty for gastrointestinal Frequency: death. (monitor liver Combined use may breathing, and discomfort during oral IV q8 enzymes closely in heighten wheezing. administration. suspected hepatitis). nephrotoxicity risk. Other Adverse Classification Reactions: -Record the time of : headache, administration, the dosage Semisynthetic dizziness, fatigue, given, and any adverse cephalosporin and blood reactions observed. antibiotic disorders. -Note the patient’s progress, any side effects experienced, and the effectiveness of the medication in resolving infection symptoms. Drug Data Mechanis Indication Contraindication Drug Adverse Nursing m of action Interaction Reaction Responsibilities Generic Reduces Treating and Had previously May reduce Headache, -Administer ranitidine as Name: gastric acid preventing ulcers experienced a the dizziness, prescribed, ensuring Ranitidine secretion by in the stomach hypersensitivity absorption of diarrhea and accurate dosage and route. competitively and intestines, reaction to the drug drugs rarely hepatoxicity Brand Name: blocking where the or any of its requiring and - Encourage adequate Zantac histamine stomach components, acute acidic thrombocytopenia. hydration, either orally or receptors (H2 produces too porphyria, environment intravenously, to improve Dosage: receptors) much acid, such concurrent use with such as drug absorption and 30mg located on as Zollinger- other acid reducers ketoconazole elimination. parietal cells Ellison syndrome. and Route & in the Managing atazanavir. - If the patient is also taking Frequency: stomach gastroesophageal antacids, ensure they are IV q8 lining. This reflux disease administered at least 2 hours prevents (GERD) and before or after ranitidine to Classification: histamine erosive avoid interfering with Histamine from esophagitis. absorption. H2 Antagonists stimulating acid - Monitor for any adverse production, reactions, such as thus headache, dizziness, decreasing constipation, diarrhea, or the overall skin rash. Report any acidity of significant changes to the gastric healthcare provider. contents.
- Assess the patient's
response to the medication, including pain relief and improvement in symptoms. Monitor for potential toxicity, especially in older adults or those with liver or kidney dysfunction.