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 Essentials of
Neonatal Ventilation
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Essentials of
Neonatal Ventilation
P.K. Rajiv
DCH, MD
Fellowship in Neonatology (Australia), Prime Hospitals and Clinics, Burjuman Centre, Dubai,
United Arab Emirates (ex Professor of Neonatology Amrita Institute of Medical Sciences,
Kochi, Kerala, India)

Dharmapuri Vidyasagar
MD, FAAP, FCCM, PhD(Hon)
Professor Emeritus Pediatrics, Division of Neonatology,
University of Illinois at Chicago, Chicago, IL, United States

Satyan Lakshminrusimha
MD, FAAP
Professor and Dennis and Nancy Marks Chair of Pediatrics, Pediatrician-in-Chief,
UC Davis Children’s Hospital, University of California, Davis, Sacramento, CA, United States

Foreword by
Richard A. Polin
MD
William T. Speck, Professor of Pediatrics, College of Physicians and Surgeons,
Columbia University, New York, NY, United States
Director, Division of Neonatology, Morgan Stanley Children’s Hospital of New York-Presbyterian,
New York, NY, United States
ELSEVIER
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Essentials of Neonatal Ventilation, 1e, P.K. Rajiv, Dharmapuri Vidyasagar,

Satyan Lakshminrusimha
Copyright © 2019 by RELX India Pvt. Ltd.
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ISBN: 978-81-312-4998-7
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 Contributors

Thouseef Ahmed, MD Vineet Bhandari, MD, DNB, DM Ramasubbareddy Dhanireddy,

Specialist Neonatologist, NMC Hospital, Professor and Division Chief, Drexel MD
Dubai, United Arab Emirates University College of Medicine, University Distinguished Professor,
St. Christopher’s Hospital for Children, Professor of Pediatrics, Obstetrics and
Said A. Al-kindi, BHSc, MD,
Philadelphia, PA, United States Gynecology, University of Tennessee
DCH, MRCPCH, FRACP
Health Science Center, Memphis,
Armed Forces Hospital, Muscat, Rama Bhat, MD, FAAP TN, United States
Sultanate of Oman Professor Emeritus Pediatrics, University
of Illinois, Chicago, IL, United States Vikramaditya Dumpa, MD, FAAP
Namasivayam Ambalavanan, MD
NYU Winthrop Hospital, Mineola,
Professor of Pediatrics, University of Manoj Biniwale, MBBS, MD, NY, United States
Alabama at Birmingham, Birmingham, MRCP, MRCPCH, FAAP
AL, United States Keck School of Medicine of USC, Khaled El-Atawi, Mb.Bch, M.Sc.,
LAC+USC Medical Center, Los Angeles, PhD, iFAAP, FRCPCH (Pediatrics)
K. Shreedhara Avabratha, MD,
CA, United States & M.Sc. (HCM)
DNB (Pediatrics)
Consultant Neonatologist, Latifa
Professor, Dept of Pediatrics, Fr.Muller John P. Breinholt, III, MD
Women and Children Hospital,
Medical College, Mangaluru, Karnataka, UT Health McGovern Medical School,
DHA – Dubai, United Arab Emirates
India Houston, TX, United States
Mahmoud Saleh Elhalik, MD,
Rakhi Balachandran, MD Ilia Bresesti, MD
Amrita Institute of Medical Sciences DCH, ABP, FAAP, FRCPCH
“V. Buzzi” Children’s Hospital, Latifa Women and Children Hospital,
and Research Centre, Amrita Vishwa Milan, Italy
Vidyapeetham, Kochi, Kerala, India Dubai, United Arab Emirates
Bert Bunnell, ScD, FAIMBE
Jeya Balaji, MD Ahmed Zakaria Elmorsy,
Biomedical Engineering, University of
Fellowship in Neonatology, Professor, Mb.Bch, M.Sc. (Pediatrics)
Utah, Salt Lake City, UT, United States
Department of Pediatrics and Senior Neonatologist, Latifa Women and
Neonatology, Velammal Medical College Dinesh K. Chirla, MD, DM, Children Hospital, DHA – Dubai, United
and Research Institute, Madurai, Tamil MRCPCH, CCST Arab Emirates
Nadu, India Rainbow Children’s Hospital, Hyderabad,
Kimberly S. Firestone, MSc, RRT
Telangana, India
Dushyant Batra, MRCPCH Akron Children’s Hospital, Akron, OH,
Nottingham University Hospitals NHS Swarup K. Dash, MD, DNB United States
Trust, Nottingham, United Kingdom Senior Neonatologist, Latifa
Regan E. Giesinger, MD, FRCPC
Women and Children Hospital,
Catherine C. Beaullieu, MD University of Iowa, Iowa City,
DHA – Dubai, United Arab Emirates
UT Health McGovern Medical School, IA, United States
Houston, TX, United States Narendra Dereddy, MD, FAAP
Hariram M., MD, DCH
Associate Professor, University of
Nagamani Beligere, MD, MPH Neonatologist and Head of Pediatrics
Central Florida, Associate Medical
Associate Professor, University of Illinois Fortis Hospital, Bannerghatta Road,
Director, Neonatology at Advent
Medical Center, Chicago, IL, United States Bangalore, India
Health Hospital for Children, Orlando,
Anita Bhandari, MD FL, United States Helmut D. Hummler, MD, MBA
University of Pennsylvania, Children’s Chief Division of Neonatology,
Hospital of Philadelphia, Philadelphia, Department of Pediatrics, Professor of
PA, United States Pediatrics adj., University of Ulm, Germany

v
Contributors

Abbas Hyderi, MD, FRCPC, FAAP Satyan Lakshminrusimha, MD, Srinivas Murki, MD, DM
University of Alberta, Stollery Children’s FAAP Fernandez Hospital, Hyderabad,
Hospital, Edmonton, AB, Canada Professor and Dennis and Nancy Telangana, India
Marks Chair of Pediatrics, Pediatrician
Lucky Jain, MD, MBA K.Y. Ashok Murthy, BE
-In-Chief, UC Davis Children’s Hospital,
Richard W. Blumberg Professor and Mg Director, Erkadi Medical Systems
University of California, Davis,
Chair of Pediatrics, Chief Academic
Sacramento, CA, United States Durga P. Naidu, MD
Officer, Children’s Healthcare
of Atlanta Children’s Heart Clinic of Louisiana,
Laurance Lequier, MD, FRCPC
Lafayette, LA, United States
Stollery Children’s Hospital, University of
Jegen Kandasamy, MD
Alberta, Edmonton, AB, Canada Arun Nair, MBBS, MD (Paed),
University of Alabama at Birmingham,
Birmingham, AL, United States Gianluca Lista, MD, PhD DCH, MRCP, FRCPCH, FRACP
“V. Buzzi” Children’s Hospital, Waikato Hospital, Hamilton; Auckland
Martin Keszler, MD, FAAP University, Auckland, New Zealand
Milan, Italy
Professor of Pediatrics, Brown
University, Women and Infants Hospital, Suzanne M. Lopez, MD Jayasree Nair, MD
Providence, RI, United States UT Health McGovern Medical School, Assistant Professor of Pediatrics, Jacobs
Houston, TX, United States School of Medicine and Biomedical
Abrar A. Khan, MD Sciences, University at Buffalo, Buffalo,
Latifa Women and Children Hospital, Mohamed M A Soliman, NY, United States
Dubai, United Arab Emirates MBBCh, MSc, MRCPCH, EPIC
Specialist Paediatrics and Neonatology, Elaine Neary, MD, PhD
Junaid Muhib Khan, MD, FRCP, The Hospital of Sick Kids, Toronto,
National Research Centre, Giza, Egypt
FAAF, FAAP, CMQ ON, Canada
Al-Rahba Hospital/Johns Hopkins Manoj N. Malviya, MBBS, MRCP
Medicine International, Abu Dhabi, Josef Neu, MD
(UK)
United Arab Emirates Professor of Pediatrics, University
Khoula Hospital, Muscat, Sultanate
of Florida Health Shands Children’s
Sai Sunil Kishore M., MD of Oman
Hospital, Gainesville, FL, United States
(Pediatrics), DM (Neonatology) Mark C. Mammel, MD, FAAP
Mycure Hospital, Visakhapatnam, Donald M. Null, MD
Professor of pediatrics, University of
Andhra Pradesh, India University of California, Davis; UC Davis
Minnesota Medical Center, Saint Paul,
Children’s Hospital, Sacramento, CA,
G. Ganesh Konduri, MD MN, United States
United States
Professor of Pediatrics and Chief Prakash Manikoth, MBBS, DCH,
of Neonatology Division, Muma Nalinikant Panigrahy, MD, DNB
MRCP (UK), FRCPCH
Endowed Chair of Neonatology, Rainbow Children’s Hospital, Hyderabad,
The Royal Hospital, Muscat, Sultanate
Children’s Research Institute, Medical Telangana, India
of Oman
College of Wisconsin, Children’s
Merlin Pinto, MD
Hospital of Wisconsin, Milwaukee, Bobby Mathew, MRCP
Fellowship in Neonatology (Canada),
WI, United States Assistant Professor of Pediatrics, Jacobs
NIDCAP certified Professional, MetroHealth
School of Medicine and Biomedical
Mathew Kripail, MD Hospital, Case Western Reserve University,
Sciences, University at Buffalo, NY,
Neonatologist, Sultan Qaboos University Cleveland, OH, United States
United States
Hospital, Muscat, Oman
P.K. Rajiv, DCH, MD
Patrick J. McNamara, MB, BCh,
Raman Krishna Kumar, MD, DM Fellowship in Neonatology (Australia),
BAO, MRCP, MRCPCH
Amrita Institute of Medical Sciences Prime Hospitals and Clinics, Burjuman
Professor and Division Chief of
and Research Centre, Amrita Vishwa Centre, Dubai, United Arab Emirates
Neonatology, Stead Family Children’s
Vidyapeetham, Kochi, Kerala, India (ex Professor of Neonatology Amrita
Hospital, University of Iowa, Iowa City,
Institute of Medical Sciences, Kochi,
Praveen Kumar, DCH, MD IA, United States
Kerala, India)
Associate Chair, Department of Rafique Memon, Md(Ped)
Pediatrics, Visiting Professor of Aiman Rahmani, MD, MBA, FAAP
Fellowship Neonatology, Specialist
Pediatrics, University of Illinois, Chief Medical Officer Consultant,
Pediatrician, NMC Speciality Hospital,
Children’s Hospital of Illinois, Peoria, IL, Division of Neonatology, Clinical
Dubai, United Arab Emirates
United States Professor, Faculty of Medicine, United
Arab Emirates University, Abu Dhabi,
United Arab Emirates

vi
 Contributors

Manimaran Ramani, MBBS, MD Augusto Sola, MD Kirtikumar Upadhyay, MD, FAAP

University of Alabama at Birmingham, Director Medico Ejecutivo, SIBEN, Por los University of Tennessee Health Science
Birmingham, AL, United States recién nacidos Center, Memphis, TN, United States

Rangasamy Ramanathan, MD, Howard Stein, MD, FAAP

Karunakar Vadlamudi, MD
FAAP Promedica Toledo Children’s Hospital,
Stollery Children’s Hospital, University of
Professor of Pediatrics at the Keck University of Toledo Health Science
Alberta, Edmonton, AB, Canada
School of Medicine and Division Chief, Campus, Toledo, OH, United States
Director of Neonatal Respiratory therapy Payam Vali, MD
program, Program director, Neonatal RoseMary S. Stocks, MD,
University of California, Davis; UC Davis
Perinatal Fellowship Program, University PharmD
Children’s Hospital, Sacramento, CA,
of Southern California, Los Angeles, Department of Otolaryngology,
United States
CA, United States Head and Neck Surgery, University
of Tennessee Health Sciences Center, Máximo Vento, MD, PhD
P. Syamasundar Rao, MD, FAAP, Memphis, TN, United States University and Polytechnic Hospital La Fe
FACC, FSCAI Valencia, València, Spain
Professor of Pediatrics, Division of Sreeram Subramanian, MD, DM
Consultant, Paramitha Children’s Sudeep Verma, MD, FNB
Pediatric Cardiology, UT Health
Hospital; NEOBBC Children’s Hospital, KIMS-Institute of cardiac Sciences,
McGovern Medical School, Houston,
Hyderabad, Telangana, India Secunderabad-Hyderabad, Telangana,
TX, United States
India
Maura Helena Ferrari Resende, Gautham Suresh, MD, DM, MS,
MD FAAP Dharmapuri Vidyasagar, MD,
Section Head and Service Chief, FAAP, FCCM, PhD(Hon)
Clinical Fellow, The Hospital for Sick
Neonatology, Professor of Pediatrics, Professor Emeritus Pediatrics, Division
Children, Toronto, ON, Canada
Texas Children’s Hospital, Baylor College of Neonatology, University of Illinois at
Rakesh Sahni, MD of Medicine, Houston, TX, United States Chicago, Chicago, IL, United States
Professor of Pediatrics, Columbia
University College of Physicians and Ru-Jeng Teng, MD Koert de Waal, PhD, FRACP
Children’s Research Institute, Medical John Hunter Children’s Hospital,
Surgeons, New York-Presbyterian
College of Wisconsin, Children’s Newcastle, NSW, Australia
Morgan Stanley Children’s Hospital,
Hospital of Wisconsin, Milwaukee, WI,
Columbia University Medical Center,
New York, NY, United States United States Mark F. Weems, MD, FAAP
University of Tennessee Health Science
Mitali Sahni, MD Vikrum A. Thimmappa, MD Center, Memphis, TN, United States
Department of Otolaryngology,
Fellow in Neonatal-Perinatal Medicine,
St. Christopher’s Hospital for Children, Head and Neck Surgery, University Jen-Tien Wung, MD
of Tennessee Health Sciences Center, Professor of Pediatrics, Columbia
Drexel University College of Medicine,
Memphis, TN, United States University College of Physicians and
Philadelphia, PA, United States
Surgeons, Columbia University Medical
Marwa al Sayyed, MBBS, MSc Jerome W. Thompson, MD, MBA Center, New York, NY, United States
Department of Otolaryngology,
Neonatal Registrar, NMC speciality
Hospital, Dubai, United Arab Emirates
Head and Neck Surgery, University Hakam Yaseen, MD, CES (Paed),
of Tennessee Health Sciences Center, DUN (Neonat) [France], CCST
Bernard Schoonakker, MRCPCH Memphis, TN, United States (UK), FRCPCH [UK]
Nottingham University Hospitals NHS University of Sharjah, Medical Director
David A. Todd, FIMLS, MSc,
Trust, Nottingham, United Kingdom (CMO), University Hospital Sharjah
PhD, MBBS
(UHS), Sharjah, United Arab Emirates
Craig Smith, MRCPCH Centenary Hospital, Canberra, ACT,
Nottingham University Hospitals NHS Australia
Trust, Nottingham, United Kingdom

vii