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2 Red Cell Typing Methods-Introduction

Red cell typing methods are crucial to prevent antibody responses in recipients during blood transfusions. The most significant antibodies are those against ABO and Rh blood group antigens, which are routinely typed in donor blood samples. Confirmation of ABO and Rh types occurs both at the time of donation and before transfusion for recipients.

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2 Red Cell Typing Methods-Introduction

Red cell typing methods are crucial to prevent antibody responses in recipients during blood transfusions. The most significant antibodies are those against ABO and Rh blood group antigens, which are routinely typed in donor blood samples. Confirmation of ABO and Rh types occurs both at the time of donation and before transfusion for recipients.

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azirakam145
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© © All Rights Reserved
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RED CELL TYPING METHODS

If the antigens on a donor’s red cells are not an identical match to those of the recipient, transfused blood is capable
of inducing an antibody response in the recipient. Thus, it is important to identify the antigenic substances on both
the donor’s red cells and those of the intended recipient.

The most immunogenic and clinically important antibodies are those directed against antigens of the ABO and Rh
blood groups. Donor blood samples are routinely typed for ABO and Rh at the time of donation. The ABO group is
confirmed when the Red Blood Cell unit is received in the hospital’s transfusion service, and the Rh type is
confirmed on units labeled Rh negative. Recipient samples are typed before transfusion.

Copyright © 2017 by the AABB. All rights reserved.

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