Study-Package-5_Set-1_Chapter-15
Study-Package-5_Set-1_Chapter-15
Solutions
SECTION - A
Objective Type Questions
1. Which of the following toxic substance is responsible for the chill and high fever recurring every three to four
days in malaria?
Haemozoin– Malarial parasite digest haemoglobin and release high quantities of free heme, this free heme is
toxic to cells and parasite convert it into an insoluble crystalline form called haemozoin.
2. In which of the following disorder, the alveoli get filled with fluid leading to severe problems in respiration?
(1) Common cold (2) Whooping cough (3) Diphtheria (4) Pneumonia
Pneumonia: It is characterised by infection of lungs. Due to filling of fluid in alveoli gas exchange cannot occur
properly loading to severe problems in respiration.
(1) Widal test (2) Mantoux test (3) Schick test (4) Dick test
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6. Internal bleeding, muscular pain, fever, anaemia and blockage of the intestinal passage are the common
symptoms of
7. Among the noninfectious diseases, which of the following is most common fatal diseases of human beings?
8. Which of the following fish is introduced in pond to control or eliminate the vector responsible for the
transmission of malaria and filariasis?
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9. The use of vaccines and immunisation programmes have enabled us to completely eradicate a deadly disease
like
10. In the life cycle of Plasmodium, sexual stages (gametocytes) begin to develop in
(1) Stomach of mosquito (2) Intestine of man (3) Liver of man (4) Red blood cells of man
Sol. Answer (4)
Gametocyte begin to form in RBC of man and completes its further development to form gametes as sexual
cycle in mosquito.
11. Out of the following diseases which are caused due to bacterial infection?
a. Typhoid
b. Elephantiasis
c. Cholera
d. Tuberculosis
(1) a & b only (2) b & c only (3) a, c & d only (4) a, b, c & d
Sol. Answer (3)
Typhoid, Cholera and Tuberculosis are caused by bacteria. Elephantiasis is caused by helminth.
12. The pathogens of genera, Microsporum, Trichophyton and Epidermophyton are responsible for
(1) Botulism (2) Conjunctivitis (3) Ringworm (4) Skin allergy
Sol. Answer (3)
It is a fungal disease caused by Microsporum, Trichophyton, Epidermophyton.
Botulism– (Food poisining)– Clostridium botulinum– bacterial disease.
Conjunctivitis– Viral, bacterial or an allergic reaction.
Skin Allergy– Caused by different allergens.
13. Which of the following is a non-specific type of defense that is present at the time of birth?
(1) Acquired immunity (2) Humoral immune response
(3) Cell mediated immunity (4) Innate immunity
Sol. Answer (4)
It is non-specific as it act against any type of foreign agent .
Acquired Immunity– It is pathogen specific and it initiates when a host encounters pathogen during first attack
Humoral Immunity– Type of acquired immunity– B-lymphocyte mediated in which antibodies are produced.
Cell mediated immunity– T-lymphocyte mediated.
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14. Acid in stomach, saliva in the mouth, tears from eyes, all prevent microbial growth belong to which of the
following barrier?
IgA– Colostrum is a golden liquid substance that a nursing mother expels from her breasts 24-48 hours after
delivery.
IgG– Only antibody that can cross the placenta and confer immunity to the foetus.
(1) Artificially acquired passive immunity (2) Artificially acquired active immunity
(3) Naturally acquired active immunity (4) Naturally acquired passive immunity
Because in this preformed antibodies against snake venom are directly injected into the human body.
Naturally acquired passive immunity– IgA and IgG antibodies from mother to baby and foetus respectively.
Naturally acquired active immunity– Acquired when antigens gain access into the body during natural infection.
17. The use of anti-histamine, adrenaline and steroids quickly reduces the symptoms of
(1) Fungal diseases (2) Viral diseases (3) Allergy (4) Helminthic diseases
Allergic reaction is due to the release of chemicals like histamine and serotonin from mast cells and use of
drugs like anti-histamine, adrenaline and steroids quickly reduces the symptoms of allergy.
Fungal diseases, viral diseases and helminthic infections can be prevented by personal hygiene.
22. Which one of the following techniques is safest for the detection of cancers?
(1) Magnetic Resonance Imaging (MRI) (2) Radiography (X-rays)
(3) Computed Tomography (CT) (4) Histopathological studies
Sol. Answer (1)
MRI uses strong magnetic fields and non-ionising radiations to accurately detect pathological and physiological
changes in the living tissues.
Histopathological studies involves surgery which may cause harm to body. Radiography and computed
tomography involves use of X-rays.
23. Smoking increases ______ content in blood and reduces the concentration of haembound oxygen. Fill the
blank suitably
(1) Carbon dioxide (2) Carbaminohaemoglobin
(3) Carbon monoxide (4) Carboxylic acid
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When the smoke is inhaled into lungs, CO is rapidly absorbed into blood stream and it binds to the
haemoglobin in the red blood cells 200 times more effectively than oxygen does.
24. Which of the following drug is extracted from the latex of poppy plant Papaver somniferum, generally taken
by snorting and injection, is a depressant and slows down body functions?
Cocaine: obtained from Erythroxylum coca, generally snorted. Causes hallucinations, and has a potent effect
on central nervous system, producing a sense of euphoria and increased energy.
Hashish: Obtained from Cannabis plant, taken by inhalation and oral ingestion.
Barbiturates: It is a sedative.
Used as a medicine to help patients cope with mental illness like depression, insomnia etc.
Reduces excitement by depressing the CNS activity and lowers physiological activity leading to drownsiness
or sleep.
SECTION - B
Objective Type Questions
(3) Common cold is characterised by nasal congestion and discharge, sore throat, hoarseness, cough,
headache, tiredness etc.
(4) Droplets resulting from cough or sneezes of an infected person are inhaled directly or transmitted through
contaminated objects and can cause infection in a healthy person
3. Wuchereria bancrofti, the filarial worm that causes elephantiasis belongs to phylum
(1) Platyhelminthes (2) Aschelminthes (3) Coelenterate (4) Arthropoda
Sol. Answer (2)
4. Recently chikungunya and dengue cases were reported from various parts of the country. Choose the correct
vector responsible for these diseases
(1) Anopheles mosquito (2) Xenopsylla (Rat flea) (3) Culex mosquito (4) Aedes mosquito
Sol. Answer (4)
Culex mosquito– Vector of Wuchereria bancrofti which causes Elephantiasis.
Xenopsylla– Vector of Yersinia pestis which causes plague.
Anopheles mosquito– Vector of Plasmodium which causes malaria.
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Solution of Assignment Human Health and Disease 9
12. Oncogene is another name for
(1) Inducer gene (2) Jumping gene (3) Structural gene (4) Cancer causing gene
Sol. Answer (4)
Cellular oncogenes (c-onc) or proto-oncogenes have been identified in normal cells. Which when activated under
certain conditions, could lead to oncogenic transformation of the cells.
Cancer causing virus called oncogenic virus have genes called viral oncogenes.
Inducer gene: A molecule that regulate gene expression.
Jumping genes: Genes that can change their position within the genome.
Structural gene: Genes that codes for any RNA or protein product other than a regulatory protein.
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18. A person who met with road accident is likely to develop tetanus he is immunised by administering
(1) Weakened germs (2) Dead germs
(3) Preformed antibodies (4) Wide spectrum antibiotics
Sol. Answer (3)
Preformed antibodies are injected in such injury as pathogen i.e., Clostridium tetani produces a neurotoxin-
tetanospasmin and a quick response is required to stop the action of antigen which is not done by the
formation of our own antibodies as it takes time.
Weakened germs and dead germs are used in vaccine to develop immunity against them.
Wide spectrum antibiotics is used when a person is suffering from many diseases or infections but not for a
single disease/infection.
20. L.S.D. is
(1) Hallucinogenic (2) Sedative (3) Stimulant (4) Tranquiliser
Sol. Answer (1)
Hallucinogens change one's behaviour, thoughts, feelings and perceptions without any actual sensory stimulus.
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Solution of Assignment Human Health and Disease 11
Sedative: Barbiturate and benzodiazepines – Depress brain activity and produce feelings of calmness,
relaxation, drowsiness and deep sleep.
Stimulant: Caffeine, cocaine, amphetamines– Stimulate nervous system, increases alertness, produce
excitement.
Tranquilisers: Benzodiazepines– Act as anti-depressants.
21. Tick mark the incorrect match with respect to the drug, source and its action.
SECTION - C
Previous Years Questions
1. Grafted kidney may be rejected in a patient due to [Re-AIPMT-2015]
(1) Innate immune response (2) Humoral immune response
(3) Cell-mediated immune response (4) Passive immune response
Sol. Answer (3)
Cell mediated immunity (CMI) is responsible for graft rejection.
2. If you suspect major deficiency of antibodies in a person, to which of the following would you look for
confirmatory evidence? [Re-AIPMT-2015]
(1) Serum globulins (2) Fibrinogen in plasma (3) Serum albumins (4) Haemocytes
Sol. Answer (1)
Antibodies are present in serum. They are glycoproteins and also called gammaglobulins synthesized in lymph
nodes.
3. Which of the following immunoglobulins does constitute the largest percentage in human milk?
[Re-AIPMT-2015]
(1) IgG (2) IgD (3) IgM (4) IgA
Sol. Answer (4)
IgA is present in external body secretion including colostrum and milk. They provide naturally acquired passive
immunity to child.
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5. Which of the following viruses is not transferred through semen of an infected male? [AIPMT-2015]
(1) Ebola virus (2) Hepatitis B virus
(3) Human immunodeficiency virus (4) Chikungunya virus
Sol. Answer (4)
Chikungunya is caused by Arbovirus and transmitted through the bite of Aedes mosquito.
7. Which of the following is not one of the prime health risks associated with greater UV radiation through the
atmosphere due to depletion of stratospheric ozone? [AIPMT-2015]
(1) Increased liver cancer (2) Increased skin cancer
(3) Reduced Immune System (4) Damage to eyes
Sol. Answer (1)
Liver cancer can be caused due to aflatoxin (released by Aspergillus fungus), Vinyl chloride but UV-rays do
not cause cancer of liver.
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Solution of Assignment Human Health and Disease 13
9. Which one of the following fungi contains hallucinogens? [AIPMT-2014]
(1) Morchella esculenta (2) Amanita muscaria (3) Neurospora sp. (4) Ustilago sp.
Sol. Answer (2)
Amanita muscaria is noted for its hallucinogenic properties, with its main psychoactive constituent being the
compound muscimol.
10. Which is the particular type of drug that is obtained from the plant whose one flowering branch is shown below?
[AIPMT-2014]
11. At which stage of HIV infection does one usually show symptoms of AIDS? [AIPMT-2014]
(1) Within 15 days of sexual contact with an infected person
(2) When the infected retro virus enters host cells
(3) When HIV damages large number of helper T lymphocytes
(4) When the viral DNA is produced by reverse transcriptase
Sol. Answer (3)
Fall in number of helper T-lymphocytes causes lowering of immunity.
13. The cell-mediated immunity inside the human body is carried out by [NEET-2013]
(1) B lymphocytes (2) Thrombocytes (3) Eythrocytes (4) T lymphocytes
Sol. Answer (4)
14. Select the correct statement regarding the specific disorder of muscular or skeletal system
[AIPMT (Prelims)-2012]
(1) Myasthenia gravis - Auto immune disorder which inhibits sliding of myosin filaments
(2) Gout - Inflammation of joints due to extra deposition of calcium
(3) Muscular dystrophy - Age related shortening of muscles
(4) Osteoporosis - Decrease in bone mass and higher chances of fractures with advancing age
Sol. Answer (4)
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15. Common cold differs from pneumonia in, that [AIPMT (Prelims)-2012]
(1) Pneumonia pathogen infects alveoli whereas the common cold affects nose and respiratory passage but
not the lungs
(2) Pneumonia is a communicable disease whereas the common cold is a nutritional deficiency disease
(3) Pneumonia can be prevented by a live attenuated bacterial vaccine whereas the common cold has no
effective vaccine
(4) Pneumonia is caused by a virus while the common cold is caused by the bacterium Haemophilus
influenzae
Sol. Answer (1)
Pneumonia pathogen infects alveoli whereas the common cold affects nose and respiratory passage but not
the lungs.
18. Which one of the following is not a property of cancerous cells whereas the remaining three are ?
[AIPMT (Prelims)-2012]
(1) They show contact inhibition
(2) They compete with normal cells for vital nutrients
(3) They do not remain confined in the area of formation
(4) They divide in an uncontrolled manner
Sol. Answer (1)
They do not show contact inhibition. Contact inhibition is a properly of normal cells in which dividing cells
when in contact with other cells are inhibited for their uncontrolled growth.
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Solution of Assignment Human Health and Disease 15
20. In which one of the following options the two examples are correctly matched with their particular type of
immunity? [AIPMT (Prelims)-2012]
Examples Type of immunity
(1) Mucus coating of epithelium lining the urinogenital – Physiological barriers
tract and the HCl in stomach
(2) Polymorphonuclear leukocytes and monocytes – Cellular barriers
(3) Anti-tetanus and anti-snake bite injections – Active immunity
(4) Saliva in mouth and tears in eyes – Physical barriers
Sol. Answer (2)
The corrected match are:
(1) Saliva in mouth and tears in eyes– Physiological barriers.
(2) Mucus coating of epithelium lining the urinogenital tract– Physical barrier.
(3) Anti-tetanus and anti-snake bite injections– Passive immunity.
21. Which one of the following sets of items in the options 1-4 are correctly categorised with one exception in
it? [AIPMT (Mains)-2012]
Items Category Exception
22. Identify the molecules (a) and (b) shown below and select the right option giving their source and use
CH3
O
N CH3 OH
O
H
(a) O (b) OH
H O
[AIPMT (Mains)-2012]
Options :
(2) (b) Heroin Cannabis sativa Depressant and slows down body functions
23. Which one of the following statements is correct with respect to immunity? [AIPMT (Mains)-2012]
(1) Rejection of a kidney graft is the function of B lymphocytes
(2) Preformed antibodies need to be injected to treat the bite by a viper snake
(3) The antibodies against small pox pathogen are produced by T lymphocytes
(4) Antibodies are protein molecules, each of which has four light chains
Sol. Answer (2)
Preformed antibodies need to be injected to treat the bite by a viper snake.
(2) The antibodies against small pox pathogen are produced by B-lymphocytes.
(3) Antibodies are protein molecules, each of which has 2 heavy chain and 2 light chains.
(4) Rejection of a kidney graft is the function of T-lymphocytes.
25. Which one of the following acts as a physiological barrier to the entry of microorganisms in human body?
[AIPMT (Prelims)-2011]
(1) Skin (2) Epithelium of urogenital tract
(3) Tears (4) Monocytes
Sol. Answer (3)
26. Where will you look for the sporozoites of the malarial parasite? [AIPMT (Prelims)-2011]
(1) Salivary glands of freshly moulted female Anopheles mosquito
(2) Saliva of infected female Anopheles mosquito
(3) Red blood corpuscles of humans suffering form malaria
(4) Spleen of infected humans
Sol. Answer (2)
Salivary glands of infected female Anopheles mosquito contains sporozoites.
Life cycle of malaria takes place in liver and RBC of human not in spleen.
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Solution of Assignment Human Health and Disease 17
27. A certain patient is suspected to be suffering form Acquired Immuno Deficiency Syndrome. Which diagnostic
technique will you recommend for its detection? [AIPMT (Prelims)-2011]
(1) WIDAL (2) ELISA (3) MRI (4) Ultrasound
Sol. Answer (2)
Enzyme linked immuno sorbent assay– Test that uses antibodies and colour change to identify HIV (antigen).
WIDAL– Typhoid
MRI– Magnetic Resonance Imaging– Cancer.
Ultrasound– Used in medical imaging (visual representation of interior of body).
28. Select the correct statement with respect to diseases and immunisation [AIPMT (Mains)-2011]
(1) Certain protozoans have been used to mass produce hepatitis B vaccine
(2) Injection of snake antivenom against snake bite is an example of active immunisation
(3) If due to some reason B and T lymphocytes are damaged, the body will not produce antibodies against
a pathogen
(4) Injection of dead / inactivated pathogens causes passive immunity
Sol. Answer (3)
29. Read the following statement having two blanks (A and B).
“A drug used for __ (A)__ patients is obtained from a species of the organism __(B)__ .”
The one correct option for the two blanks is [AIPMT (Mains)-2011]
Blank-A Blank-B
(1) Swine flu Monascus
(2) AIDS Pseudomonas
(3) Heart Penicillium
(4) Organ transplant Trichoderma
Sol. Answer (4)
31. Which one of the following options gives the correct matching of a disease with its causative organism and
mode of infection [AIPMT (Mains)-2011]
Disease Causative Organisms Mode of Infection
(1) Elephantiasis Wuchereria bancrofti With infected water and food
(2) Malaria Plasmodium vivax Bite of male Anopheles mosquito
(3) Typhoid Salmonella typhi With inspired air
(4) Pneumonia Streptococcus pneumoniae Droplet infection
Sol. Answer (4)
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32. The pathogen Microsporum responsible for ringworm disease in humans belongs to the same Kingdom of
organisms as that of [AIPMT(Mains)-2011]
(1) Rhizopus, a mould (2) Ascaris, a round worm
(3) Taenia, a tapeworm (4) Wuchereria, a filarial worm
Sol. Answer (1)
33. Select the correct statement from the ones given below: [AIPMT (Prelims)-2010]
(1) Barbiturates when given to criminals make them tell the truth
(2) Morphine is often given to persons who have undergone surgery as a pain killer.
(3) Chewing tobacco lowers blood pressure and heart rate
(4) Cocaine is given to patients after surgery as it stimulates recovery
Sol. Answer (2)
35. Which one of the following statements is correct with respect to AIDS? [AIPMT (Prelims)-2010]
(1) The causative HIV retrovirus enters helper T lymphocytes thus reducing their numbers
(2) The HIV can be transmitted through eating food together with an infected person
(3) Drug addicts are least susceptible to HIV infection
(4) AIDS patients are being fully cured cent per cent with proper care and nutrition
Sol. Answer (1)
36. Fastest distribution of some injectible material/ medicine and with no risk of any kind can be achieved by
injecting it into the [AIPMT (Mains)-2010]
(1) Muscles (2) Arteries (3) Veins (4) Lymph vessels
Sol. Answer (3)
37. Which one of the following techniques is safest for the detection of cancers? [AIPMT (Mains)-2010]
(1) Magnetic resonance imaging (MRI) (2) Radiography (X-ray)
(3) Computed tomography (CT) (4) Histopathological studies
Sol. Answer (1)
38. A person suffering from a disease caused by Plasmodium, experiences recurring chill and fever at the time
when? [AIPMT (Mains)-2010]
(1) The sporozoites released from RBCs are being rapidly killed and broken down inside spleen
(2) The trophozoites reach maximum growth and give out certain toxins
(3) The parasite after its rapid multiplication inside RBCs ruptures them, releasing the stage to enter fresh
RBCs
(4) The microgametocytes and megagametocytes are being destroyed by the WBCs
Sol. Answer (3)
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Solution of Assignment Human Health and Disease 19
39. Which one of the following cannot be used for preparation of vaccines against plague? [AIPMT (Mains)-2010]
(1) Formalin-inactivated suspensions of virulent bacteria
(2) Avirulent live bacteria
(3) Synthetic capsular polysaccharide material
(4) Heat-killed suspensions of virulent bacteria
Sol. Answer (3)
40. Consider the following four statements (a–d) regarding kidney transplant and select the two correct ones out
of these.
a. Even if a kidney transplant is proper the recipient may need to take immuno-suppresants for a long
time.
b. The cell-mediated immune response is responsible for the graft rejection.
c. The B lymphocytes are responsible for rejection of the graft.
d. The acceptance or rejection of a kidney transplant depends on specific interferons.
The two correct statements are [AIPMT (Prelims)-2010]
(1) a & b (2) b & c (3) c & d (4) a & c
Sol. Answer (1)
Corrected statements are:
c. The T-lymphocytes are responsible for rejection of the graft.
d. The acceptance or rejection of a kidney transplant depends on matching of tissue.
42. Alzheimer disease in humans is associated with the deficiency of [AIPMT (Prelims)-2009]
(1) Glutamic acid (2) Acetylcholine
(3) Gamma aminobutyric acid (GABA) (4) Dopamine
Sol. Answer (2)
44. Use of anti-histamines and steroids give a quick relief from [AIPMT (Prelims)-2009]
(1) Nausea (2) Cough (3) Headache (4) Allergy
Sol. Answer (4)
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45. To which type of barriers under innate immunity, do the saliva in the mouth and the tears from the eyes, belong?
[AIPMT (Prelims)-2008]
(1) Physical barriers (2) Cytokine barriers (3) Cellular barriers (4) Physiological barriers
Sol. Answer (4)
46. Match the disease in Column I with the appropriate items (pathogen/prevention/treatment) in Column II
Column I Column II
a. Amoebiasis (i) Treponema palladium
b. Diphtheria (ii) Use only sterilized food and water
c. Cholera (iii) DPT Vaccine
d. Syphilis (iv) Use oral rehydration therapy [AIPMT (Prelims)-2008]
(1) a(ii), b(iii), c(iv), d(i) (2) a(i), b(ii), c(iii), d(iv) (3) a(ii), b(iv), c(i), d(iii) (4) a(ii), b(i), c(iii), d(iv)
Sol. Answer (1)
47. Which one of the following is the correct statement regarding the particular psychotropic drug specified?
[AIPMT (Prelims)-2008]
(1) Barbiturates cause relaxation and temporary euphoria
(2) Hashish causes after thought perceptions and hallucinations
(3) Opium stimulates nervous system and causes hallucinations
(4) Morphine leads to delusions and disturbed emotions
Sol. Answer (2)
The corrected statments are:
(1) Barbiturates depresses brain activity and produce feeling of calmness, relaxation.
(3) Opium suppresses brain function and produce temporary euphoria.
(4) Morphine relieve pain and called analgesic.
48. Cornea transplant in humans is almost never rejected. This is because [AIPMT (Prelims)-2008]
(1) It is a non-living layer (2) Its cells are least penetrable by bacteria
(3) It has no blood supply (4) It is composed of enucleated cells
Sol. Answer (3)
49. Ultrasound of how much frequency is beamed into human body for sonography? [AIPMT (Prelims)-2007]
(1) 45–70 MHz (2) 30–45 MHz (3) 15–30 MHz (4) 1–15 MHz
Sol. Answer (4)
50. Lysozyme that is present in perspiration, saliva and tears, destroys [AIPMT (Prelims)-2007]
(1) Most virus-infected cells (2) Certain fungi
(3) Certain types of bacteria (4) All viruses
Sol. Answer (3)
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Solution of Assignment Human Health and Disease 21
51. A person showing upredictable moods, outbursts of emotion, quarrelsome behaviour and conflicts with others
is suffering from [AIPMT (Prelims)-2006]
(1) Schizophrenia (2) Borderline personality disorder (BPD)
(3) Mood disorders (4) Addictive disorders
Sol. Answer (2)
53. Both sickle cell anaemia and Huntington’s chorea are [AIPMT (Prelims)-2006]
(1) Bacteria-related diseases (2) Congenital disorders
(3) Pollutant-induced disorders (4) Virus-related diseases
Sol. Answer (2)
55. Which one of the following depresses brain activity and produces feelings of calmness, relaxation and
drowsiness? [AIPMT (Prelims)-2005]
(1) Valium (2) Morphine (3) Hashish (4) Amphetamines
Sol. Answer (1)
57. Aggregates of lymphoid tissue present in the distal portion of the small intestine are known as
(1) Villi (2) Peyer's patches (3) Rugae (4) Choroid plexus
Sol. Answer (2)
Villi– small, finger- like projections that protrude from thee epithelial lining of intestinal wall.
Rugae– large folds in the mucous membrane.
Choroid plexus– is a plexus in the ventricles of the brain where cerebrospinal fluid is produced.
58. Which of the following is not the main function of lymph glands?
(1) Forming RBC (2) Destroying bacteria (3) Forming WBC (4) Forming antibodies
Sol. Answer (1)
RBCs are formed in bone marrow.
Lymph glands serve to trap micro-organisms or other antigens which are present in lymph and tissues fluid.
These antigens activate lymphocytes which destroy these antigens.
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22 Human Health and Disease Solution of Assignment
59. Which one of the following is important as one of the first line of defence against inhaled and ingested
pathogen?
(1) IgA (2) IgG (3) IgM (4) IgD
Sol. Answer (1)
It is the main immunoglobulin found in mucous secretions, tears, saliva, sweat, colostrum and secretions from
urinogenital tract, gastro genital tract, prostate and respiratory epithelium, which are all physical and
physiological barriers of innate immunity.
62. The main reason why antibiotics could not solve all the problems of bacteria mediated disease is
(1) Decreased efficiency of the immune system
(2) Insensitivity of the individual following prolonged exposure to antibiotics
(3) Development of mutant strains resistant to antibiotics
(4) Activation of antibiotics by bacterial enzymes
Sol. Answer (3)
Antibiotics could not solve all the problems of bacteria medicated disease because due to continuous exposure
to antibiotics bacteria develops resistance against these antibiotics by undergoing mutations.
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Solution of Assignment Human Health and Disease 23
65. Human immuno deficiency virus (HIV) has a protein coat and a genetic material which is
(1) Double stranded RNA (2) Double stranded DNA
66. Which of the following is a viral glycoprotein that plays a role in the infection of human cells by HIV?
(1) gp 120 (2) CD4 (3) CCR5 (4) Both (1) & (3)
68. The modern idea about ageing is that our body slowly loses the power of defence against the invasion of germs
and pathogens. This process starts by the disappearance of which organ?
(1) Pituitary gland (2) Spleen (3) Thymus gland (4) Parathyroid gland
Sol. Answer (3)
Thymus provides an inductive environment for development of T-cells. Thymus begins atrophy (partial or complete
wasting away of a part of the body) with age which slows down the power of defence against the invasion of
germs.
(3) Natural cannabinoids are obtained from the inflorescence of the plant Cannabis sativa
(4) LSD (Lysergic Acid Diethylamide) is most powerful hallucinogen extracted from Papaver somniferum
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24 Human Health and Disease Solution of Assignment
70. Which one of the following sets of items in the options (1) - (4) are incorrectly categorised with one exception
in it?
72. Short-lived immunity acquired from mother to foetus across placenta or through mother’s milk to the infant
is categorised as
(1) Active immunity (2) Passive immunity
(3) Cellular immunity (4) Innate non-specific immunity
Sol. Answer (2)
As readymade antibodies move across the placenta from mother to foetus.
Active immunity– When antibodies are produced in host body itself.
Cellular immunity: Immunity mediated by different type cells in body.
Innate non-specific immunity: Immunity present at the time of birth.
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Solution of Assignment Human Health and Disease 25
Sol. Answer (1)
This is true about T-cells in mammals.
The corrected statements are:
(2) These originate in primary lymphoid tissues (bone marrow)
(3) Phagocytic cells like monocytes scavenge damaged cells and cellular debris.
(4) These get mature in thymus.
74. Which of the following pairs of diseases is viral as well as transmitted by mosquitoes?
(1) Elephantiasis and dengue (2) Yellow fever and sleeping sickness
(3) Encephalitis and sleeping sickness (4) Yellow fever and dengue
Sol. Answer (4)
Yellow fever and dengue are caused by virus and transmitted by Aedes mosquito.
Elephantiasis : Helminthic disease, transmitted by Culex mosquito.
Sleeping sickness : Protozoan disease, transmitted by tse-tse fly.
SECTION - D
Assertion-Reason Type Questions
1. A : Live attenuated vaccine is better in terms of immunity provided to the recipient.
R : As secondary lymphoid organs, example peyer's patches are stimulated to protect the individual.
Sol. Answer (1)
2. A : Asthma patients must never be exposed to dust.
R : Allergic response may cause vasoconstriction and death.
Sol. Answer (4)
Asthma patients can be exposed to dust but they should avoid exposure to dust as it can act as an allergen.
Allergic response may cause vasodilation and death.
3. A : Colostrum is a very efficient means of transferring immunity to a newborn.
R : IgM from mother’s milk protects the baby from the respiratory infection usually affecting in young age.
Sol. Answer (3)
Colostrum is very efficient means of transferring immunity to new born because it has abundant antibodies (IgA)
to protect the infant.
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26 Human Health and Disease Solution of Assignment
IgA from mother's milk protects the baby from the respiratory infection usually affecting in young age.
4. A : Vaccine against AIDS has not been made inspite of repeated attempts.
R : HIV has the ability to get mutated to form several subtypes.
Sol. Answer (1)
5. A : Antibiotics like penicillin can be used to treat common cold.
R : Penicillin causes lysis of viral cells.
Sol. Answer (4)
Antibiotics like penicillin are taken against bacterial disease and common cold is viral disease.
Penicillin causes lysis of bacterial cells not viral cells.
6. A : It is considered advantageous to give the polio vaccine orally.
R : It prevents reinfection by causing intestinal immunity.
Sol. Answer (1)
7. A : Typhoid carriers may be cured by surgical removal of their gall bladder.
R : The disease germs remain concentrated in it.
Sol. Answer (1)
The bacteria of typhoid remain in gall bladder.
8. A : Cancer is contagious and cells can spread from one person to other.
R : Cancerous cells are highly dedifferentiated cells.
Sol. Answer (4)
Cancer is not contagious and cells do not spread from one person to other.
9. A : A person who has received a cut accidentally and is bleeding needs to be given anti-tetanus treatment.
R : Anti-tetanus injection provides active immunity by providing preformed antibodies for tetanus.
Sol. Answer (3)
A person who has received a cut accident and is bleeding needs to be given anti-tetanus treatment because
antigen causing tetanus may have entered the body against which preformed antibodies have to be injected
to avoid the effect of antigen.
Anti-tetanus injection provides passive immunity by providing preformed antibodies for tetanus.
10. A : LSD and marijuana are clinically used as analgesics.
R : Both these drugs suppress brain function.
Sol. Answer (4)
LSD and marijuana are hallucinogens.
Both these drugs do not suppress brain function instead they alter thoughts, feelings and perceptions.
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