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Metformin-Titration-Sheet

Metformin 500mg tablets are prescribed to control diabetes by improving blood glucose levels through various mechanisms. Common side effects include digestive issues, which may diminish over time, and it is recommended to start with a low dose and gradually increase it. Patients should follow a specific titration schedule and consult their diabetes team if side effects persist after dose adjustments.

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21 views2 pages

Metformin-Titration-Sheet

Metformin 500mg tablets are prescribed to control diabetes by improving blood glucose levels through various mechanisms. Common side effects include digestive issues, which may diminish over time, and it is recommended to start with a low dose and gradually increase it. Patients should follow a specific titration schedule and consult their diabetes team if side effects persist after dose adjustments.

Uploaded by

octavio071000
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© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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Metformin 500mg Immediate Release Tablets Information

Sheet
Introduction
You have been prescribed metformin 500mg tablets to help control your diabetes.
Metformin improves your blood glucose control by:

• Slowing down the release of glucose stored in your liver


• Helping insulin carry glucose from your blood stream into muscle and fat cells
more effectively
The most common side effects of metformin therapy are digestive problems, such as
nausea (feeling sick), vomiting (being sick), diarrhoea, abdominal (tummy) pain,
increased flatulence (wind) and loss of appetite. These side effects commonly
happen at the beginning of treatment, but often reduce after a few weeks.
To avoid these side effects, it is best to take metformin with or after a meal, and to
start on a low dose of Metformin, building up gradually to the dose recommended by
your diabetes team.

Recommended titration
Please follow the guidelines below and dosing schedule overleaf:
Step 1: Take 1 x 500mg tablet daily after your evening meal for 2 weeks

Step 2: Take 2 x 500mg tablets each day for 2 weeks. You can take:

• 1 tablet with breakfast and 1 tablet with dinner or


• 2 tablets with your evening meal
Step 3: Take 3 x 500mg tablets each day. You should take 2 tablets with
breakfast and 1 tablet with your evening meal
Step 4: Take 4 x 500mg tablets each day. This should be 2 tablets with breakfast
and 2 tablets with your evening meal.

Important information
Wait until your body has got used to the medicine before increasing the dose. Most
people can increase the number of tablets every 2 weeks but it may take longer. If
after an increase in dose you do experience unpleasant side effects, you may need
to drop back to the previous dose. If side effects are not settling down after 2 weeks
then make an appointment with a member of your GP Practice diabetes team rather
than stopping your medication.
Starting metformin 500mg tablets and increasing your dose

Breakfast Lunch Dinner Bedtime

Week
1

Week
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Week
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Week
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Week
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Week
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Week
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Onwards

Additional notes from your GP:

Document History
Version: V 1.1
Author: SWL Diabetes Clinical Network
Approved by: Integrated medicines committee (IMOC)
Approval date: 15th February 2023
Review Date: 15th February 2025

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