chapter 3
chapter 3
2) Which of the following is the study of tissues and groups of specialized cells and cell products
that work together to perform specific functions?
A) cytology
B) anatomy
C) histology
D) physiology
E) embryology
Answer: C
Learning Outcome: 3.1
Bloom's Taxonomy: 1-2: Remembering/Understanding
6) Which type of epithelium is found in portions of the respiratory tract and includes a mixture of
cell types whose nuclei are situated at varying distances from the surface?
A) simple squamous
B) simple cuboidal
C) stratified columnar
D) stratified cuboidal
E) pseudostratified columnar
Answer: E
Learning Outcome: 3.1
Bloom's Taxonomy: 1-2: Remembering/Understanding
8) The presence of large numbers of microvilli on the exposed surfaces of epithelial cells
indicates that ________.
A) it is an area where absorption and secretion occur
B) these cells provide energy for transport activities
C) these cells are probably located along portions of the respiratory tract from the lungs toward
the throat
D) All of the answers are correct.
E) None of the answers are correct.
Answer: A
Learning Outcome: 3.1
Bloom's Taxonomy: 1-2: Remembering/Understanding
9) Stereocilia are described by which of the following?
A) present in the epithelium of the female reproductive tract
B) very short microvilli
C) present on receptor cells of the inner ear
D) manufactured by the Golgi apparatus
E) All of the answers are correct.
Answer: C
Learning Outcome: 3.1
Bloom's Taxonomy: 1-2: Remembering/Understanding
10) Which type of epithelium is present where easy exchange of materials out of the blood is
most important, such as that in the lining of the heart and all blood vessels?
A) stratified squamous
B) stratified columnar
C) simple cuboidal
D) endothelium
E) simple columnar
Answer: D
Learning Outcome: 3.1
Bloom's Taxonomy: 1-2: Remembering/Understanding
15) What type of epithelium comprises the inner lining of the ventral body cavity?
A) simple squamous epithelium
B) stratified epithelium
C) columnar epithelium
D) mesothelium
E) endothelium
Answer: D
Learning Outcome: 3.1
Bloom's Taxonomy: 1-2: Remembering/Understanding
16) Which type of epithelium lines the renal pelvis, ureters, and urinary bladder?
A) cuboidal
B) columnar
C) transitional
D) squamous
E) glandular
Answer: C
Learning Outcome: 3.1
Bloom's Taxonomy: 1-2: Remembering/Understanding
17) The epithelium lining the small intestine of the digestive tract is ________.
A) stratified squamous
B) simple columnar
C) stratified columnar
D) simple squamous
E) None of the answers are correct.
Answer: B
Learning Outcome: 3.1
Bloom's Taxonomy: 1-2: Remembering/Understanding
22) An epithelium always has an exposed surface, which is referred to as the ________ surface.
A) basal
B) lateral
C) apical
D) intercellular
E) basolateral
Answer: C
Learning Outcome: 3.1
Bloom's Taxonomy: 1-2: Remembering/Understanding
24) The ________ is a complex structure produced by the epithelium and cells of the underlying
connective tissue.
A) apical surface
B) basement membrane
C) ciliated epithelium
D) microvillus
E) stereocilium
Answer: B
Learning Outcome: 3.1
Bloom's Taxonomy: 1-2: Remembering/Understanding
25) ________ epithelia are quite rare; they are found lining the ducts of sweat glands and in
larger ducts of some other exocrine glands, such as mammary glands.
A) Simple cuboidal
B) Simple squamous
C) Stratified columnar
D) Stratified cuboidal
E) Stratified squamous
Answer: D
Learning Outcome: 3.1
Bloom's Taxonomy: 1-2: Remembering/Understanding
31) Most energy storage in the body is accomplished by which of the following cells?
A) adipocytes
B) melanocytes
C) macrophages
D) fibroblasts
E) lymphocytes
Answer: A
Learning Outcome: 3.2
Bloom's Taxonomy: 1-2: Remembering/Understanding
32) Small, mobile connective tissue cells that release chemicals (after injury or infection), which
stimulate the inflammatory response, are known as ________.
A) lymphocytes
B) adipocytes
C) microphages
D) free macrophages
E) mast cells
Answer: E
Learning Outcome: 3.2
Bloom's Taxonomy: 1-2: Remembering/Understanding
33) The type of cartilage that is specialized to resist compression is ________.
A) osteocartilage
B) fibrous cartilage
C) elastic cartilage
D) hyaline cartilage
E) All of the answers are correct.
Answer: B
Learning Outcome: 3.2
Bloom's Taxonomy: 1-2: Remembering/Understanding
35) Which of the following comprises a list of the most closely related connective tissue types?
A) adipose tissue, tendon, blood, lymph, bone
B) elastic cartilage, fibrocartilage, skin
C) tendon, blood, lymph, reticular tissue
D) areolar tissue, tendon, bone, cartilage
E) reticular tissue, areolar, adipose tissue
Answer: E
Learning Outcome: 3.2
Bloom's Taxonomy: 1-2: Remembering/Understanding
36) Extracellular fibers and ________ comprise the matrix that surrounds the cells of a
connective tissue.
A) melanocytes
B) ground substance
C) fibroblasts
D) mesenchymal cells
E) neutrophils and eosinophils
Answer: B
Learning Outcome: 3.2
Bloom's Taxonomy: 1-2: Remembering/Understanding
37) The connective tissue type that has a distinctive population of cells suspended in a fluid
matrix is called ________.
A) cartilage
B) reticular tissue
C) blood
D) lymph
E) osseous tissue
Answer: C
Learning Outcome: 3.2
Bloom's Taxonomy: 1-2: Remembering/Understanding
39) The relatively few ________ residing in connective tissues engulf damaged or dead cells or
invading pathogens, and release chemicals that attract many more cells to activate the immune
system.
A) mast cells
B) mesenchymal cells
C) fibrocytes
D) fixed macrophages
E) monocytes
Answer: D
Learning Outcome: 3.2
Bloom's Taxonomy: 1-2: Remembering/Understanding
40) When a local injury or infection damages or destroys connective tissues, the ________
respond by dividing to produce daughter cells that differentiate into fibroblasts, or other
connective tissue cells.
A) resting macrophages
B) fibrocytes
C) mucoid connective tissue
D) mesenchymal cells
E) mast cells
Answer: D
Learning Outcome: 3.2
Bloom's Taxonomy: 1-2: Remembering/Understanding
41) A(n) ________ consists of 3 fibrous protein subunits wound together like the strands of a
rope; it is flexible, yet very strong when pulled by either end.
A) collagen fiber
B) parenchyma
C) elastic fiber
D) reticular fiber
E) fibroblast
Answer: A
Learning Outcome: 3.2
Bloom's Taxonomy: 1-2: Remembering/Understanding
42) ________ is highly vascularized, very active biochemically, and its individual cells contain
numerous mitochondria, which gives the tissue a deep, rich color.
A) Elastic tissue
B) Reticular tissue
C) White adipose tissue
D) Areolar connective tissue
E) Brown adipose tissue
Answer: E
Learning Outcome: 3.2
Bloom's Taxonomy: 1-2: Remembering/Understanding
43) ________ tissue provides a supporting framework of the liver, spleen, bone marrow, and
lymph nodes.
A) Dense irregular
B) Areolar
C) Adipose
D) Elastic
E) Reticular
Answer: E
Learning Outcome: 3.2
Bloom's Taxonomy: 1-2: Remembering/Understanding
44) Tendons, aponeuroses, and ligaments are all composed of ________ connective tissue, which
contains tightly packed collagen fibers aligned parallel to applied forces.
A) dense regular
B) osseous
C) cartilaginous
D) reticular
E) areolar
Answer: A
Learning Outcome: 3.2
Bloom's Taxonomy: 1-2: Remembering/Understanding
45) Elastic connective tissues ________.
A) are comprised of collagenous sheets or ribbons that resemble flat, broad tendons
B) often contain significant numbers of elastic fibers as well as collagen fibers; and usually
connect cartilage-to-cartilage, bone to cartilage, or one bone to another bone
C) often underlie transitional epithelia; and are also found in the walls of blood vessels and
surrounding the respiratory passageways
D) are actually cords of dense regular connective tissue that attach skeletal muscles to bones and
cartilage
E) form an interwoven meshwork and do not show any consistent pattern; it provides strength
and support to areas subjected to stresses from many directions
Answer: C
Learning Outcome: 3.2
Bloom's Taxonomy: 1-2: Remembering/Understanding
46) The fibers in ________ connective tissue form an interwoven meshwork that does not show
any consistent pattern, but maintains tensile strength in all directions.
A) reticular
B) dense irregular
C) periosteal
D) areolar
E) elastic
Answer: B
Learning Outcome: 3.2
Bloom's Taxonomy: 1-2: Remembering/Understanding
47) In cartilage, ________ growth occurs when stem cells of the inner layer of the perichondrium
divide repeatedly; the innermost cells differentiate into chondroblasts that produce new cartilage
matrix.
A) superficial
B) appositional
C) subserous
D) interstitial
E) synovial
Answer: B
Learning Outcome: 3.2
Bloom's Taxonomy: 1-2: Remembering/Understanding
50) Which of the following describes the major function of serous membranes?
A) Each consists of a mesothelium supported by dense connective tissue.
B) They line body cavities that communicate with the exterior.
C) They are loosely attached to the body wall and to the organs they cover.
D) Their parietal and visceral portions never touch.
E) Tiny amounts of transudate formed on the surfaces of the membrane reduce friction.
Answer: E
Learning Outcome: 3.3
Bloom's Taxonomy: 1-2: Remembering/Understanding
51) Which of the following consists of extensive areas of areolar tissue bounded by an
incomplete superficial layer of squamous or cuboidal cells?
A) superficial fascia
B) cutaneous membrane
C) sarcolemma
D) mucous membrane
E) synovial membrane
Answer: E
Learning Outcome: 3.3
Bloom's Taxonomy: 1-2: Remembering/Understanding
54) The areolar tissue component of a mucous membrane is called the ________.
A) lamina lucida
B) transudate
C) lamina propria
D) mesothelium
E) lamina densa
Answer: C
Learning Outcome: 3.3
Bloom's Taxonomy: 1-2: Remembering/Understanding
55) The ________, a type of serous membrane, covers the lungs and lines the thoracic cavity.
A) peritoneum
B) pleura
C) parenchyma
D) pericardium
E) periosteum
Answer: B
Learning Outcome: 3.3
Bloom's Taxonomy: 1-2: Remembering/Understanding
58) Loose connective tissue layers that lie between deep fascia and serous membranes, and line
body cavities is called ________.
A) superficial fascia
B) intermuscular fascia
C) subcutaneous layer
D) subserous fascia
E) hypodermis
Answer: D
Learning Outcome: 3.4
Bloom's Taxonomy: 1-2: Remembering/Understanding
59) The superficial fascia, also called the ________, is the layer of loose connective tissue that
separates the skin from underlying tissues and organs.
A) cutaneous fascia
B) dermis
C) intermuscular fascia
D) subcutaneous layer
E) reticular lamina
Answer: D
Learning Outcome: 3.4
Bloom's Taxonomy: 1-2: Remembering/Understanding
60) The layer of dense regular connective tissue that is bound to capsules, tendons, and ligaments
is called ________.
A) deep fascia
B) subserous fascia
C) lamina propria
D) reticular lamina
E) subcutaneous layer
Answer: A
Learning Outcome: 3.4
Bloom's Taxonomy: 1-2: Remembering/Understanding
61) Muscle tissue located in layers around the digestive tract is called ________.
A) smooth muscle
B) crenulated muscle
C) skeletal muscle
D) cardiac muscle
E) All of the answers are correct.
Answer: A
Learning Outcome: 3.5
Bloom's Taxonomy: 1-2: Remembering/Understanding
63) Skeletal muscle tissue contains large fibers that are ________.
A) multinucleated
B) involuntary
C) nonstriated
D) controlled by pacesetter cells
E) connected by intercalated discs
Answer: A
Learning Outcome: 3.5
Bloom's Taxonomy: 1-2: Remembering/Understanding
67) Although skeletal muscle fibers cannot divide, new muscle fibers can be produced through
the division of ________, which are stem cells that persist in adult skeletal muscle.
A) pacemaker cells
B) myosatellite cells
C) osteocytes
D) periosteal stem cells
E) mast cells
Answer: B
Learning Outcome: 3.5
Bloom's Taxonomy: 1-2: Remembering/Understanding
68) Cardiac muscle fibers form extensive connections with one another at specialized regions
called ________.
A) sarcolemmae
B) intermuscular fascia
C) soma
D) intercalated discs
E) striations
Answer: D
Learning Outcome: 3.5
Bloom's Taxonomy: 1-2: Remembering/Understanding
69) Which of the following is a cell process that receives incoming electrical impulses?
A) soma
B) neuroglia
C) dendrites
D) nerve fibers
E) axon
Answer: C
Learning Outcome: 3.6
Bloom's Taxonomy: 1-2: Remembering/Understanding
74) During embryological development, the actual embryo is formed by the ________.
A) inner cell mass
B) trophoblast
C) blastocyst
D) mesoderm
E) zygote
Answer: A
Learning Outcome: 3.8
Bloom's Taxonomy: 1-2: Remembering/Understanding
75) In the formation of a(n) ________, the connecting cells disappear, and the cells secrete into
blood vessels or into the surrounding tissue fluids.
A) loose connective tissue
B) endocrine gland
C) respiratory epithelium
D) exocrine gland
E) cutaneous membrane
Answer: B
Learning Outcome: 3.8
Bloom's Taxonomy: 1-2: Remembering/Understanding
1) Multiple layers of cells, found where mechanical stresses are severe, are called simple
cuboidal epithelium.
Answer: FALSE
Learning Outcome: 3.1
Bloom's Taxonomy: 1-2: Remembering/Understanding
2) Cuboidal cells resemble little hexagonal boxes, which appear square in typical sectional
views.
Answer: TRUE
Learning Outcome: 3.1
Bloom's Taxonomy: 1-2: Remembering/Understanding
3) Transitional cells are relatively tall, slender cells with nuclei in a narrow band close to the
basement membrane.
Answer: FALSE
Learning Outcome: 3.1
Bloom's Taxonomy: 1-2: Remembering/Understanding
4) In eccrine secretion, secretory products are released from gland cells through exocytosis onto
the surface of the cell.
Answer: TRUE
Learning Outcome: 3.1
Bloom's Taxonomy: 1-2: Remembering/Understanding
5) Apocrine secretion occurs when gland cells shed the apical portion of their cytoplasm, which
has become packed with secretory vesicles.
Answer: TRUE
Learning Outcome: 3.1
Bloom's Taxonomy: 1-2: Remembering/Understanding
6) Endocrine secretions are discharged, often through a duct, onto the surface of the skin or on
the epithelial lining of an internal passageway that communicates with the exterior.
Answer: FALSE
Learning Outcome: 3.1
Bloom's Taxonomy: 1-2: Remembering/Understanding
7) Holocrine secretion occurs when a gland cell becomes packed with secretory products and
then bursts apart; the secretion is released and the cell dies.
Answer: TRUE
Learning Outcome: 3.1
Bloom's Taxonomy: 1-2: Remembering/Understanding
8) Exocrine secretory products (hormones) are released, via exocytosis from the gland cells, into
the fluid surrounding the cells.
Answer: FALSE
Learning Outcome: 3.1
Bloom's Taxonomy: 1-2: Remembering/Understanding
10) Pads between the spinal vertebrae consist of the structural material called hyaline cartilage.
Answer: FALSE
Learning Outcome: 3.2
Bloom's Taxonomy: 1-2: Remembering/Understanding
11) The tough but somewhat flexible material that covers the articular surfaces within synovial
joints is hyaline cartilage.
Answer: TRUE
Learning Outcome: 3.2
Bloom's Taxonomy: 1-2: Remembering/Understanding
12) Cords of dense regular connective tissue that attach skeletal muscles to bones and cartilage
are called tendons.
Answer: TRUE
Learning Outcome: 3.2
Bloom's Taxonomy: 1-2: Remembering/Understanding
13) Relatively long, cylindrical, and multinucleate cells are characteristic of skeletal muscle
cells.
Answer: TRUE
Learning Outcome: 3.4
Bloom's Taxonomy: 1-2: Remembering/Understanding
3.3 Essay Questions
1) What are the main structural differences between cartilage and bone?
Answer: In cartilage, blood vessels are absent and chondrocytes occupy lacunae; whereas, in
bone, vascularity is extensive and osteocytes reside in lacunae. Cartilage has a matrix that is
equivalent to a firm gel, consisting of chondroitin sulfates with proteins that form hydrated
proteoglycans, and collagen, elastic, and reticular fibers whose proportions vary according to the
type of cartilage. This combination gives cartilage the quality of limited strength in that it bends
easily but is difficult to break. In contrast, bone matrix is comprised of insoluble crystals of
calcium phosphate and calcium carbonate, and collagen fibers predominate. Together, these
constituents attribute the quality of strength and limited flexibility to bone, making it very
resistant to shattering. Other structural and characteristic differences are as follows: cartilage is
externally covered by a 2-layered perichondrium; bone is covered by a 2-layered periosteum;
cartilage has low oxygen demand and receives nutrients by diffusion through the matrix;
whereas, bone has high oxygen demand and receives nutrients by diffusion through the
cytoplasm and fluid in canaliculi.
Learning Outcome: 3.2
Bloom's Taxonomy: 3-4: Applying/Analyzing
2) In what regions of the body could you expect to find dense irregular connective tissue, and
why would the tissue be located in these regions?
Answer: Dense irregular connective tissue is found in the dermis, where it gives the skin
strength and allows it to resist stresses from many directions. Except at joints, dense irregular
connective tissue also forms a sheath around cartilage (the perichondrium) and bone (the
periosteum), thus mainly providing external protection. It also forms a thick, fibrous capsule that
surrounds many internal organs, such as the liver, kidneys, and spleen. And it encloses the
cavities of joints. Its function in these cases is to also provide strength and support to such areas
subjected to stresses from many directions.
Learning Outcome: 3.2
Bloom's Taxonomy: 3-4: Applying/Analyzing
5) Why is the ability of cardiac muscle to repair itself more limited than that of smooth muscle?
Answer: Cardiac muscle fibers are incapable of dividing, and cardiac muscle tissue lacks
myosatellite cells, which divide to produce new muscle fibers. Thus, cardiac muscle tissue
damaged by injury or disease cannot regenerate. However, smooth muscles cells can divide, and
smooth muscle tissue can therefore regenerate after an injury.
Learning Outcome: 3.5
Bloom's Taxonomy: 3-4: Applying/Analyzing
3.4 Labeling Questions
Figure 3.1
3) What type of epithelium comprises the lining of the peritoneal cavity, which is featured in the
top group of diagrams (Fig. 3.1a)?
A) Simple cuboidal
B) Simple columnar
C) Simple squamous
D) Transitional
E) Stratified cuboidal
Answer: C
Learning Outcome: 3.1
Bloom's Taxonomy: 1-2: Remembering/Understanding
7) What type of epithelium comprises the surface of the tongue, which is featured in the bottom
group of diagrams (Fig. 3.1 b)?
A) Stratified columnar
B) Pseudostratified columnar
C) Stratified cuboidal
D) Stratified squamous
E) Transitional
Answer: D
Learning Outcome: 3.1
Bloom's Taxonomy: 1-2: Remembering/Understanding
Figure 3.2
Using the figure above, identify the gland features and types.
Figure 3.4