Scribd
Upload
24 views1 page

MPH201T-MPHARM-WINTER-2019

This document outlines the examination details for the Molecular Pharmaceutics course at Gujarat Technological University, including instructions for the exam and a list of questions covering topics such as gene therapy, pulmonary drug delivery, microcapsules, nanoparticles, tumor targeting, and challenges in drug delivery. Students are required to attempt any five questions, making suitable assumptions where necessary. The exam is scheduled for December 2, 2019, with a total of 80 marks available.

Uploaded by

Kanisha Ranpariya
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
24 views1 page

MPH201T-MPHARM-WINTER-2019

This document outlines the examination details for the Molecular Pharmaceutics course at Gujarat Technological University, including instructions for the exam and a list of questions covering topics such as gene therapy, pulmonary drug delivery, microcapsules, nanoparticles, tumor targeting, and challenges in drug delivery. Students are required to attempt any five questions, making suitable assumptions where necessary. The exam is scheduled for December 2, 2019, with a total of 80 marks available.

Uploaded by

Kanisha Ranpariya
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
You are on page 1/ 1

Seat No.: _____ Enrolment No.

_____________

GUJARAT TECHNOLOGICAL UNIVERSITY


M. Ph. SEMESTER– II• EXAMINATION – WINTER -2019

Subject Code:MPH201T Date: 02/12/2019


Subject Name: Molecular Pharmaceutics (Nano Tech and Targeted DDS)
Time:02:30PM TO 05:30PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.

Q.1 (a) Give importance of gene therapy over convention therapy. Can it be used in 06
treatment of diabetes? If yes, How?
(b) Discuss liposome as gene carrier. 05
(c) Discuss challenges for gene delivery through different routes of administration. 05
Q.2 (a) Write a note on metered dose inhalers as a tool for pulmonary drug delivery. 06
(b) Give your comments: 05
i) MMAD is an important parameter for pulmonary drug delivery.
ii) Nasal route can be used for brain targeting.
(c) Discuss evaluation of aerosols in detail. 05
Q.3 (a) Enlist methods of preparing Micro capsules. Discuss Coacervation Phase 06
Separation technique in detail.
(b) Compare and contrast Microcapsules and Microspheres. 05
(c) Discuss method of preparing monoclonal antibodies. 05
Q.4 (a) Enlist types of nanoparticles. Write a note on solid lipid nanoparticles. 06
(b) Discuss film hydration method of liposome preparation. 05
(c) Give your comments: 05
i) Saturation solubility is always constant and it cannot be changed.
ii) Liposomes and Micelles are structurally and functionally same.
Q.5 (a) Enlist strategies of tumor targeting. Discuss passive targeting in brief. 06
(b) Elaborate hindrances to brain targeting. Suggest ways to overcome them. 05
(c) Discuss role of metallic nano particles in tumor targeting. 05
Q. 6 (a) Write a note on lipids used for liposome preparation. 06
(b) Discuss any one bottom up technique of nano particle preparation. 05
(c) Discuss applications of Niosomes. 05
Q.7 (a) Discuss challenges of pulmonary drug delivery. Suggest their remedies. 06
(b) Write a note on supercritical fluid as a tool to produce nano particles. 05
(c) Write a note on antisense molecules. 05

***************

You might also like