Bio
Bio
1. Chemistry of Life
Water’s emergent properties: cohesion/adhesion, high specific heat, solvent abilities, density
anomaly (ice floats).
Biological macromolecules
Carbohydrates: mono- vs. polysaccharides; glycosidic linkage; energy (starch, glycogen) &
structure (cellulose, chitin).
Lipids: triglycerides vs. phospholipids; saturated vs. unsaturated; membrane fluidity; steroids
(cholesterol, hormones).
Proteins: amino acids; four structural levels; enzymes (induced fit, Vmax, Km, cofactors,
inhibitors).
Nucleic acids: nucleotide structure; 5'→3' polymerization; base-pairing; ATP as energy currency.
Organelles & their roles: nucleus (transcription), ribosome (translation), ER, Golgi, lysosome,
mitochondrion (ATP), chloroplast (photosynthesis), cytoskeleton (motor proteins, microtubules).
3. Cellular Energetics
Enzyme kinetics: temperature/pH effects, cooperativity, feedback inhibition.
Mitosis vs. meiosis and genetic variation (crossing-over, independent assortment, random
fertilization).
Central dogma: transcription (RNA pol, promoters, splicing), translation (ribosome sites,
wobble).
Ecosystems: energy flow (10 % rule), nutrient cycles (N, C, P), trophic levels, keystone species,
human impact (climate change, eutrophication).