SDS - R-FC5 EN - 2024.01.11
SDS - R-FC5 EN - 2024.01.11
TIOXIDE® R-FC5
Version Revision Date: SDS Number:
2.6 2024/01/11 400001007131
Date of first issue: 2016/03/29
Restrictions on use : Do not use for cosmetics, food additives, drug additives, feed
additives or permanent implant applications.
Due to lack of related experience or data, the supplier cannot
approve this use.
2. HAZARDS IDENTIFICATION
GHS Classification
Not a hazardous substance or mixture.
Handling and/or processing of this material may generate a dust which can cause mechanical
irritation of the eyes, skin, nose and throat.
SDS_TW-P I – – 400001007131 1 / 19
SAFETY DATA SHEET
TIOXIDE® R-FC5
Version Revision Date: SDS Number:
2.6 2024/01/11 400001007131
Date of first issue: 2016/03/29
3. COMPOSITION/INFORMATION ON INGREDIENTS
CAS-No. : 13463-67-7
Synonyms : None
Hazardous components
In case of eye contact : Rinse immediately with plenty of water, also under the eyelids.
Remove contact lenses.
Protect unharmed eye.
If eye irritation persists, consult a specialist.
Most important symptoms : Dust contact with the eyes can lead to mechanical irritation.
and effects, both acute and Inhalation of dust may cause shortness of breath, tightness of
delayed the chest, a sore throat and cough.
The product is not irritant but as with all fine powders can
absorb moisture and natural oils from the surface of the skin
during prolonged exposure.
Individuals with sensitive skin may experience skin drying on
prolonged or repeated exposure.
SDS_TW-P I – – 400001007131 2 / 19
SAFETY DATA SHEET
TIOXIDE® R-FC5
Version Revision Date: SDS Number:
2.6 2024/01/11 400001007131
Date of first issue: 2016/03/29
Protection of first-aiders : No action shall be taken involving any personal risk or without
suitable training.
5. FIREFIGHTING MEASURES
Personal precautions, : No action shall be taken involving any personal risk or without
protective equipment and suitable training.
emergency procedures Prevent unauthorised persons entering the zone.
Avoid dust formation.
Remove all sources of ignition.
Ventilate the area.
Avoid breathing dust.
Keep people away from and upwind of spill/leak.
Only qualified personnel equipped with suitable protective
equipment may intervene.
Never return spills in original containers for re-use.
Treat recovered material as described in the section "Disposal
considerations".
For disposal considerations see section 13.
The danger areas must be delimited and identified using
relevant warning and safety signs.
Environmental precautions : Try to prevent the material from entering drains or water
courses.
If the product contaminates rivers and lakes or drains inform
respective authorities.
SDS_TW-P I – – 400001007131 3 / 19
SAFETY DATA SHEET
TIOXIDE® R-FC5
Version Revision Date: SDS Number:
2.6 2024/01/11 400001007131
Date of first issue: 2016/03/29
Handling
Technical measures
: Ensure that eyewash stations and safety showers are close to
the workstation location.
Storage
Conditions for safe storage : Store in accordance with the particular national regulations.
Keep only in the original container in a cool, well ventilated
place away from oxidizing agents.
Keep in a dry place.
SDS_TW-P I – – 400001007131 4 / 19
SAFETY DATA SHEET
TIOXIDE® R-FC5
Version Revision Date: SDS Number:
2.6 2024/01/11 400001007131
Date of first issue: 2016/03/29
Hand protection
Directive : Use gloves approved to relevant standards e.g. EN 374
(Europe), F739 (US).
SDS_TW-P I – – 400001007131 5 / 19
SAFETY DATA SHEET
TIOXIDE® R-FC5
Version Revision Date: SDS Number:
2.6 2024/01/11 400001007131
Date of first issue: 2016/03/29
Skin and body protection : Personal protective equipment for the body should be
selected based on the task being performed and the risks
involved and should be approved by a specialist before
handling this product.
Hygiene measures : Handle in accordance with good industrial hygiene and safety
practice.
Smoking, eating and drinking should be prohibited in the
application area.
Wash face, hands and any exposed skin thoroughly after
handling.
Remove contaminated clothing and protective equipment
before entering eating areas.
Barrier creams may help to protect the exposed areas of
skin, they should however not be applied once exposure has
occurred.
Wash hands before breaks and at the end of workday.
Appearance : powder
Colour : white
Odour : slight
pH : Not applicable
SDS_TW-P I – – 400001007131 6 / 19
SAFETY DATA SHEET
TIOXIDE® R-FC5
Version Revision Date: SDS Number:
2.6 2024/01/11 400001007131
Date of first issue: 2016/03/29
Solubility(ies)
Water solubility : Not applicable
SDS_TW-P I – – 400001007131 7 / 19
SAFETY DATA SHEET
TIOXIDE® R-FC5
Version Revision Date: SDS Number:
2.6 2024/01/11 400001007131
Date of first issue: 2016/03/29
Symptoms of Overexposure : Dust contact with the eyes can lead to mechanical
irritation.Inhalation of dust may cause shortness of breath,
tightness of the chest, a sore throat and cough.The product is
not irritant but as with all fine powders can absorb moisture
and natural oils from the surface of the skin during prolonged
exposure.
Individuals with sensitive skin may experience skin drying on
prolonged or repeated exposure.
Acute toxicity
Components:
titanium dioxide:
Acute oral : LD50 (Rat, female): > 5,000 mg/kg
toxicityComponents Method: OECD Test Guideline 425
Assessment: The substance or mixture has no acute oral
toxicity
aluminium oxide:
Acute oral : LD50 (Rat, male and female): > 10,000 mg/kg
toxicityComponents Method: OECD Test Guideline 401
Components:
titanium dioxide:
Acute inhalation toxicity
: LC50 (Rat, male and female): 3.43 - 5.09 mg/l
Exposure time: 4 h
Test atmosphere: dust/mist
Method: OECD Test Guideline 403
Assessment: The substance or mixture has no acute
inhalation toxicity
aluminium oxide:
Acute inhalation toxicity : LC50 (Rat, male and female): > 2.3 mg/l
Exposure time: 4 h
Test atmosphere: dust/mist
Method: OECD Test Guideline 403
Assessment: The substance or mixture has no acute
inhalation toxicity
Components:
titanium dioxide:
Acute dermal toxicity
: LD50 Dermal (Rabbit): > 10,000 mg/kg
SDS_TW-P I – – 400001007131 8 / 19
SAFETY DATA SHEET
TIOXIDE® R-FC5
Version Revision Date: SDS Number:
2.6 2024/01/11 400001007131
Date of first issue: 2016/03/29
Skin corrosion/irritation
Components:
titanium dioxide:
Species: Rabbit
Assessment: No skin irritation
Method: OECD Test Guideline 404
Result: Normally reversible injuries
aluminium oxide:
Species: Rabbit
Assessment: No skin irritation
Method: OECD Test Guideline 404
Result: No skin irritation
Components:
titanium dioxide:
Species: Rabbit
Result: Normally reversible injuries
Assessment: No eye irritation
Method: OECD Test Guideline 405
aluminium oxide:
Species: Rabbit
Result: No eye irritation
Assessment: No eye irritation
Method: OECD Test Guideline 405
Components:
titanium dioxide:
Test Type: Local lymph node assay (LLNA)
Exposure routes: Skin
Species: Mouse
Assessment: Does not cause skin sensitisation.
Method: OECD Test Guideline 429
Result: Does not cause skin sensitisation.
aluminium oxide:
Exposure routes: Skin
Species: Guinea pig
Result: Does not cause skin sensitisation.
Components:
titanium dioxide:
Assessment:
No skin irritation, No eye irritation
Does not cause skin sensitisation., Does not cause respiratory
SDS_TW-P I – – 400001007131 9 / 19
SAFETY DATA SHEET
TIOXIDE® R-FC5
Version Revision Date: SDS Number:
2.6 2024/01/11 400001007131
Date of first issue: 2016/03/29
sensitisation.
Chronic toxicity
Components:
titanium dioxide:
Genotoxicity in vitro
: Test Type: Ames test
Concentration: 100 - 200 ug/plate
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Components:
titanium dioxide:
Genotoxicity in vivo : Test Type: Micronucleus test
Species: Mouse (males)
Application Route: Inhalation
Exposure time: 5 consecutive days
Dose: 0.8, 7.2, and 28.5 mg/m³
Method: OECD Test Guideline 474
Result: negative
Components:
titanium dioxide:
Germ cell mutagenicity- : Tests on bacterial or mammalian cell cultures did not show
Assessment mutagenic effects., Animal testing did not show any mutagenic
effects.
SDS_TW-P I – – 400001007131 10 / 19
SAFETY DATA SHEET
TIOXIDE® R-FC5
Version Revision Date: SDS Number:
2.6 2024/01/11 400001007131
Date of first issue: 2016/03/29
Carcinogenicity
Components:
titanium dioxide:
Species: Rat, male and female
Application Route: Oral
Exposure time: 103 weeks
Dose: 0, 25000, 50000 ppm
Frequency of Treatment: 7 days/week
NOAEL: > 50.000 ppm
Venator has examined all of the available animal carcinogenicity and mechanistic data together
with workplace epidemiology data for titanium dioxide and concludes that the weight of scientific
evidence indicates that there is no causative link between titanium dioxide exposure and cancer
risk in humans and that workplace exposures in compliance with applicable exposure standards
will not result in lung cancer or chronic respiratory diseases in humans.
Components:
titanium dioxide:
Carcinogenicity - : Not classifiable as a human carcinogen.
Assessment
Reproductive toxicity
Components:
aluminium oxide:
Effects on fertility
: Species: Rat, male and female
Application Route: Oral
Dose: 1000 milligram per kilogram
Method: OECD Test Guideline 422
Result: Animal testing did not show any effects on fertility.
Components:
titanium dioxide:
Effects on foetal
development : Species: Rat, male and female
Application Route: Oral
Dose: 100, 300, and 1000 mg/kg bw/
Duration of Single Treatment: 20 d
Frequency of Treatment: 7 days/week
General Toxicity Maternal: No observed adverse effect level:
1,000 mg/kg body weight
Developmental Toxicity: No observed adverse effect level:
1,000 mg/kg body weight
Method: OECD Test Guideline 414
Result: No adverse effects
aluminium oxide:
Species: Rat
SDS_TW-P I – – 400001007131 11 / 19
SAFETY DATA SHEET
TIOXIDE® R-FC5
Version Revision Date: SDS Number:
2.6 2024/01/11 400001007131
Date of first issue: 2016/03/29
Components:
titanium dioxide:
Reproductive toxicity - : No evidence of adverse effects on sexual function and fertility,
Assessment or on development, based on animal experiments.
Components:
titanium dioxide:
Species: Rat, male and female
: 3500 mg/m3
Application Route: Ingestion
Test atmosphere: dust/mist
Exposure time: 2 yr
Number of exposures: 5 d
Method: Chronic toxicity
Components:
titanium dioxide:
Repeated dose toxicity - : No skin irritation, No eye irritation
Assessment No adverse effect has been observed in chronic toxicity tests.
Aspiration toxicity
No data available
SDS_TW-P I – – 400001007131 12 / 19
SAFETY DATA SHEET
TIOXIDE® R-FC5
Version Revision Date: SDS Number:
2.6 2024/01/11 400001007131
Date of first issue: 2016/03/29
No data available
Neurological effects
No data available
Further information
Product:
Remarks: No data available
Ecotoxicity
Components:
titanium dioxide:
Toxicity to fish
: LC50 (Cyprinodon variegatus (sheepshead minnow)): >
10,000 mg/l
Exposure time: 96 h
Test Type: semi-static test
Test substance: Marine water
Method: OECD Test Guideline 203
aluminium oxide:
Toxicity to fish : LC50 (Fish): > 50 mg/l
Exposure time: 96 h
Test Type: static test
Test substance: Fresh water
Components:
aluminium oxide:
Toxicity to daphnia and other
aquatic invertebrates : EC50 (Daphnia magna (Water flea)): > 100 mg/l
Exposure time: 48 h
Components:
aluminium oxide:
Toxicity to algae : IC50 (Selenastrum capricornutum (green algae)): > 100 mg/l
Exposure time: 72 h
SDS_TW-P I – – 400001007131 13 / 19
SAFETY DATA SHEET
TIOXIDE® R-FC5
Version Revision Date: SDS Number:
2.6 2024/01/11 400001007131
Date of first issue: 2016/03/29
Components:
titanium dioxide:
Plant toxicity
: NOEC: 100,000 mg/kg
Exposure time: 480 h
Components:
titanium dioxide:
Sediment toxicity : (Gammarus pulex (Amphipod)): > 100000 mg/kgsedimentdw
Study: Acute
Test Type: semi-static test
Water: Fresh water
Exposure duration: 28 d
Method: ASTM Method, other
Components:
titanium dioxide:
Toxicity to terrestrial
organisms : NOEC: 10,000 mg/kg
Exposure time: 672 h
Ecotoxicology Assessment
Components:
aluminium oxide:
SDS_TW-P I – – 400001007131 14 / 19
SAFETY DATA SHEET
TIOXIDE® R-FC5
Version Revision Date: SDS Number:
2.6 2024/01/11 400001007131
Date of first issue: 2016/03/29
Components:
aluminium oxide:
Chronic aquatic toxicity
: This product has no known ecotoxicological effects.
Bioaccumulative potential
Components:
titanium dioxide:
Bioaccumulation : Species: Oncorhynchus mykiss (rainbow trout)
Bioconcentration factor (BCF): 19 - 352
Exposure time: 14 d
Test substance: Fresh water
Method: semi-static test
Remarks: Does not bioaccumulate.
SDS_TW-P I – – 400001007131 15 / 19
SAFETY DATA SHEET
TIOXIDE® R-FC5
Version Revision Date: SDS Number:
2.6 2024/01/11 400001007131
Date of first issue: 2016/03/29
Mobility in soil
Mobility
: No data available
Components:
titanium dioxide:
Distribution among
environmental compartments : Remarks: No data available
Stability in soil
: No data available
Disposal methods
Waste from residues : The product should not be allowed to enter drains, water
courses or the soil.
This material and its container must be disposed of in a safe
way.
In accordance with local and national regulations.
Dispose of wastes in an approved waste disposal facility.
If recycling is not practicable, dispose of in compliance with
local regulations.
SDS_TW-P I – – 400001007131 16 / 19
SAFETY DATA SHEET
TIOXIDE® R-FC5
Version Revision Date: SDS Number:
2.6 2024/01/11 400001007131
Date of first issue: 2016/03/29
International Regulations
IATA
Not regulated as dangerous goods
IMDG
Not regulated as dangerous goods
Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
Not applicable for product as supplied.
Inventories
SDS_TW-P I – – 400001007131 17 / 19
SAFETY DATA SHEET
TIOXIDE® R-FC5
Version Revision Date: SDS Number:
2.6 2024/01/11 400001007131
Date of first issue: 2016/03/29
AICS (Australia), DSL (Canada), IECSC (China), REACH (European Union), ENCS (Japan),
ISHL (Japan), KECI (Korea), NZIoC (New Zealand), PICCS (Philippines), TCSI (Taiwan), TSCA
(USA)
Further information
Sources of key data used to
compile the Safety Data : Information taken from reference works and the literature.,
Sheet Information derived from practical experience.
Revision Date
Name of organization that
prepared the SDS : 2024/01/11
Address and phone number : Venator Asia Sdn. Bhd. (formerly known as Huntsman P&A
of organization that prepared Asia Sdn. Bhd.)
the SDS : Level 15 The Pinnacle Persiaran Lagoon, Bandar Sunway
Petaling Jaya,
Selangor D.E. 46150
Malaysia +603 7669 9888
: Product EHS
Date format
This information is given in good faith to the best of our current reasonable knowledge, taking into
consideration current status of technology as generally applied in the industry. For updates/more
information, visit www.venatorcorp.com. NOTHING IN THIS COMMUNICATION IS (OR SHOULD
BE TAKEN AS) A WARRANTY (EXPRESS OR IMPLIED). NO REPRESENTATION, ASSURANCE
OR UNDERTAKING IS MADE. NO LIABILITY IS OR WILL BE ACCEPTED BY VENATOR IN
RELATION TO THE ADEQUACY, ACCURACY, COMPLETENESS, REASONABLENESS OF
THIS COMMUNICATION. ALL AND ANY SUCH LIABILITY IS EXPRESSLY DISCLAIMED. IN ALL
CASES IT IS YOUR RESPONSIBILITY TO DETERMINE THE APPLICABILITY OF THE
INFORMATION AND RECOMMENDATIONS AND THE SUITABILITY OF THE PRODUCTS
DESCRIBED FOR ANY PARTICULAR PURPOSE. Venator products are provided only for
manufacturing, processing, formulation, treatment and other such activities. Unless otherwise
expressly stated in this document or a valid safety data sheet, Venator products must not be used,
resold, distributed, transferred, or otherwise disposed of in (or in each case where intended to be
used in) any applications or process in: a) which lead stabilisers/stabilised systems are used where
the end product is rigid pvc; b) food; c) cosmetics; d) pharmaceuticals; or e) medical. Nothing in this
SDS_TW-P I – – 400001007131 18 / 19
SAFETY DATA SHEET
TIOXIDE® R-FC5
Version Revision Date: SDS Number:
2.6 2024/01/11 400001007131
Date of first issue: 2016/03/29
disclaimer or otherwise limits claims in respect of death or personal injury caused by our
negligence. You have full responsibility to use products consistent with safety and technical data
sheets. Once a Venator product is within your custody/control, you shall have full responsibility for
and liability arising out of its storage, handling, transportation, sale, use, reuse, recycling and/or
disposal, and of any derivative product, co-product, by-product or waste product therefrom,
including the use of any such product alone or in combination with other substances, and
compliance with any laws or regulations relating thereto. This is not: a) a license under any
intellectual property right of any entity; or b) a recommendation or authorization to action that
infringes any intellectual property right. Unless otherwise agreed in writing and signed by the
parties, all sales are subject to the Venator standard terms and conditions of sale. Reference to
Venator includes Venator Materials PLC, and any entity that it directly controls, is controlled by, or
is under common control with it, and their employees, officers, agents and distributors. All the
above applies to this document and anything else made available to you in any form or medium
(written or verbal).
SDS_TW-P I – – 400001007131 19 / 19