Reproduction_(Chapter_11)_-_The_Big_Book_of_MDCAT_by_Maqsad
Reproduction_(Chapter_11)_-_The_Big_Book_of_MDCAT_by_Maqsad
Reproduction
Section 1: Introduction
This chapter on Reproduction has been carefully designed in accordance with the PMDC guidelines to en-
sure students are well-prepared for the MDCAT exam. Reproduction is a vital life process that ensures the
continuation of species. It can be asexual, involving a single parent, or sexual, involving two parents and
the fusion of gametes. In this chapter, we will study the male and female reproductive systems, along with
the sexually transmitted diseases.
To further strengthen your understanding of Reproduction, you can watch detailed video lectures by scan-
ning the given QR code.
Section 2: Notes
Reproduction is the formation of offspring through the fission or fusion of one or both parents for the
continuity of generations, with or without variation.
Types of Reproduction
1. Asexual Reproduction – Produces identical offspring.
2. Sexual Reproduction – Produces non-identical offspring.
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Spermatogenesis Oogenesis
Production of spermatids. Production of ootids.
Occurs in the testes. Occurs in the ovaries (except during Anaphase
II and Telophase II).
Begins after puberty. Begins during the 3rd fetal month.
Continuous process. Occurs with two stopovers:
• 1st at Prophase I (Diplotene) until puberty.
• 2nd at Metaphase II, triggered by fertiliza-
tion.
Takes ~10 weeks. Takes ~1 month for one cycle.
Followed by maturation: Followed by maturation: Ootid → Ovum.
Spermatids ՜ Sperm
(Spermiogenesis).
Growth phase is short in Growth phase is long in oogonia.
spermatogonia.
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▸ Accessory Glands – Include seminal vesicles, the prostate gland, and Cowper’s glands; they pro-
duce seminal fluid.
▸ Penis – Facilitates copulation through the urethra.
Structure Description
Bulbourethral / Cowper’s Gland • Clear viscous fluid
• Lubricates urethra
Vas Deferens / Sperm Ducts • Carry sperm to urethra
• Most sperms are stored here
Prostate Gland • At the base of the urinary bladder
• Secretes mucus and alkaline fluid during ejaculation
• Neutralises acidity of vagina
Urethra • From bladder through prostate and penis to outside
• Carries urine and sperm
Epididymis • Coiled tube (6 m)
• Sperms are concentrated here (stored)
• Sperms acquire motility
Penis • Contains erectile tissue
Seminal Vesicles • Opens into sperm duct
• Contributes fructose (energy)
• Secretes mucus and alkaline fluid
Erectile Tissue • Contains blood vessels that fill with blood during arousal, allowing
for erection
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Anatomy of Testes
Structure Description
Sustentacular Cells (Sertoli Cells) Nourish and support developing sperm during spermatogenesis
Seminiferous Tubule Coiled tubules within the testis where spermatogenesis occurs;
sperm cells are produced here
Tubule Lumen The central space of the seminiferous tubule where mature sperm
are released
Rete Testis (located in Mediasti- A network of tubules that carry sperm from the seminiferous tubules
num Testis) to the efferent ductules
Efferent Ductule Carries sperm from the rete testis to the epididymis
Head of Epididymis Receives sperm from the efferent ductules and initiates maturation
Body of Epididymis The middle section of the epididymis where sperm matures further
Tail of Epididymis Stores mature sperm until ejaculation
Ductus Deferens (Vas Deferens) Transports mature sperm from the epididymis to the ejaculatory
ducts during ejaculation
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Structure Description
Gonads (Ovaries) • Ovaries are like special factories for making eggs.
• Located in the abdomen, attached to the uterus.
• Each ovary contains many follicles, which protect and nourish egg
cells.
• Born with thousands of follicles, but only a few hundred release eggs
during reproductive years.
• One follicle matures and releases an egg each menstrual cycle.
• Follicle cells produce estrogen, important for female development.
Oviducts (Fallopian Tubes) • The oviducts are like highways carrying eggs from ovaries to the uter-
us.
• Lined with cilia that help move the egg.
• Fertilisation typically happens here.
• Each oviduct is about 10 cm long.
Uterus (Womb) • A strong, muscular organ shaped like an upside-down pear.
• Located between the bladder and rectum.
• Has three parts: fundus, body, and cervix.
• The body is where the baby grows during pregnancy.
• The cervix connects to the vagina.
• Uterine wall has three layers: endometrium (innermost), myometrium
(middle), and perimetrium (outermost).
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Section 3: Test 1
1. In mammalian males, which structure is shared by the a. Progesterone
reproductive and excretory systems? b. Oxytocin
a. Vas deferens c. Luteinizing hormone (LH)
b. Ureter d. Follicle-stimulating hormone (FSH)
c. Urinary bladder
d. Urethra 10. In human females, the fertilised egg gets implanted in
the uterus:
2. Which cells within the seminiferous tubules support a. After 24 hours of fertilisation
and nourish developing sperm cells? b. After 10 days of fertilisation
a. Leydig cells c. After 14 days of fertilisation
b. Sertoli cells d. After 30 days of fertilisation
c. Spermatogonia
d. Spermatocytes 11. Which of the following is NOT the function of estro-
gen?
3. The scrotum in males is responsible for which of the a. Strengthen bones
following in the male reproductive system? E$QWLDJLQJHHFW
a. Synthesis of sperm c. Inducing feelings of fear
b. Lubrication d. Protection of heart from cholesterol
c. Temperature regulation
d. Nourishment of sperm 12. Which of the following is NOT a characteristic of sper-
matogonia?
4. Where are spermatozoa stored in the male reproduc- a.They develop into primary spermatocytes through
tive system? mitosis
a. Ejaculatory duct E7KH\DUHXQGLHUHQWLDWHG
b. Epididymis c. They are germ cells
c. Seminiferous tubule d. They are haploid
d. Vas defrens
13. In the male reproductive system, which gland neutra-
5. Which of the following is NOT a function of the lises the pH of the urethra?
placenta during pregnancy? a. Bulbourethral gland
a. Nutrient and gas exchange between mother and b. Ejaculatory gland
fetus c. Seminal vesicle gland
b. Production of hormones like hCG d. Prostate gland
c. Filtration of fetal waste into maternal blood
d. Direct transmission of maternal blood cells to the 14. Which enzyme is secreted by sperm to enter the
fetus ovum?
a. Alkaline phosphatase
6. The onset of menstruation in females is called: b. Hyaluronidase
a. Menarche c. Fructose phosphokinase
b. Ovulation d. Aminotransferase
c. Menopause
d. Lactation 15. In the human female menstrual cycle, the follicular
phase ranges from:
7. Which of the following would not be expected during a. 1-5 days
pregnancy? b. 15-28 days
a. Formation of the corpus graviditatis c. 6-14 days
b. Formation of placenta d. 11-15 days
c. Blastocyst implantation
d. Corpus albicans formation 16. Labor pains are induced by:
a. Disintegration of the placenta
8. When a female ovulates, in which phase of division is b. Contraction of the cervix
oocyte? c. Estrogen production
a. Prophase I d. Secretion of oxytocin
b. Anaphase I
c. Metaphase II 17. What event occurs in the menstrual cycle when the
d. Telophase II level of progesterone declines?
a. Menstruation
9. Which hormone primarily regulates the menstrual b. Ovulation
cycle in females? c. Fertilization
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24. At the onset of puberty in females, the pituitary gland Answer Key
releases:
a. Progesterone
d c a
b. Oxytocin b d a
c. Estrogen c a a
d. FSH
b b d
25. Fraternal twins, triplets, and quadruplets in humans d c b
occur when: a d c
a. A single fertilised egg splits into multiple embryos
d a a
b. Multiple eggs are fertilised by multiple sperm cells
c. One embryo divides repeatedly after fertilisation c c a
d. A fertilised egg splits unevenly, forming more than a a b
two cells b c d
26. A sexually transmitted disease caused by a virus and
resulting in genital ulcers is:
a. Syphilis
b. Gonorrhoeae
c. Herpes
d. AIDS
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Section 4: Solutions
1. Correct Answer: Urethra 11. Correct Answer: Inducing feelings of fear
Solution: The urethra serves as a common passage Solution: Estrogen strengthens bones, protects the
for both urine and semen. The other options (vas KHDUWDQGKDVDQWLDJLQJHHFWVEXWLVQRWDVVRFLDWHG
deferens, ureter, and urinary bladder) are not shared with fear.
between the two systems.
12. Correct Answer: They are haploid
2. Correct Answer: Sertoli cells Solution: Spermatogonia are diploid cells that under-
Solution: Sertoli cells provide structural and metabolic go mitosis and meiosis to produce haploid sperm.
support to developing sperm. Leydig cells secrete tes-
tosterone, and spermatogonia and spermatocytes are 13. Correct Answer: Bulbourethral gland
involved in spermatogenesis. Solution: The bulbourethral gland secretes an alka-
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3. Correct Answer: Temperature regulation sperm survival.
Solution: The scrotum maintains an optimal tempera-
ture for sperm production, which is lower than body 14. Correct Answer: Hyaluronidase
temperature. Solution: Hyaluronidase helps digest the protective
layer around the ovum, allowing sperm entry.
4. Correct Answer: Epididymis
Solution: The epididymis is where sperm mature and 15. Correct Answer: 6-14 days
are stored until ejaculation. Other structures (ejacula- Solution: This phase involves follicle growth and ends
tory duct, seminiferous tubule, and vas deferens) have with ovulation around day 14.
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16. Correct Answer: Secretion of oxytocin
5. Correct Answer: Direct transmission of maternal Solution: Oxytocin stimulates uterine contractions
blood cells to the fetus during labor.
Solution: The placenta facilitates nutrient and gas ex-
change and secretes hormones but maintains a barrier 17. Correct Answer: Menstruation
to prevent maternal blood cells from mixing with fetal Solution: A drop in progesterone causes the shed-
blood. ding of the uterine lining.
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Section 5: Test 2
1. The yellowish glandular structure formed after the b. Gonorrhea
release of the egg from the follicle is called: c. Syphilis
a. Corpus albicans d. Genital herpes
b. Corpus callosum
c. Corpus Luteum 11. Which STD is characterised by the presence of genital
d. Zona pellucida warts?
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2. In honey bees, males are _______ and produce sperm b. Human Papillomavirus
by ________. c. Herpes simplex virus
a. Diploid, meiosis d. Trichomoniasis
b. Haploid, mitosis
c. Haploid, meiosis 12. External fertilisation occurs in which environment?
d. Diploid, mitosis a. Terrestrial
b. Aquatic
3. In male reproductive system, which cells secrete tes- c. Aerial
tosterone? d. Airborne
a. Seminal vesicle
b. Prostate gland 13. Average loss of blood in human female during birth
c. Interstitial cells process is
d. Epididymis a. 500 ml
b. 250ml
4. All of the following are diploid cells except: c. 350ml
a. Oogonia d. 750ml
b. Primary oocyte
c. Secondary oocyte 14. Huge amount of calcium is lost by mother during:
d. Somatic cell a. Formation of fetal skeleton
b. Lactation
5. Testosterone is produced by the: c. Conception
a. Seminiferous tubules d. Birth
b. Germinal epithelium
c. Leydig cells 15. After mating, if sperm and ovum fuse, then the body
d. Sertoli cells prepares itself for pregnancy. This process is called:
a. Lactation
7KHRYDU\XQGHUWKHLQȵXHQFHRI)6+DOVRSURGXFHV b. Conception
a. Progesterone c. Fertilisation
b. Testosterone d. Menopause
c. Lactogen
d. Estrogen 16. With reference to the ovary, the postmenstrual phase
of the menstrual cycle is also called the:
:KDWVWUXFWXUHLVFXWDQGWLHGRLQDYDVHFWRP\" a. Ovulatory phase
a. Epididymis b. Follicular phase
b. Urethra c. Luteal phase
c. Seminiferous tubules d. Estrogen phase
d. Vas deferens
17. During pregnancy, the production of ova is prevented
8. Which of the following STDs is caused by a bacterium? by:
a. Gonorrhea a. Estrogen
b. Genital herpes b. Oxytocin
c. HIV AIDS c. Prolactin
d. Hepatitis B d. LH
9. When does an embryo become a fetus? 18. Parthenogenesis is a type of reproduction that re-
a. After 4 weeks quires:
b. After 6 weeks a. One gamete
c. After 8 weeks b. Two gametes
d. After 12 weeks c. Two parents
d. No parent
10. A spirochete, treponema pallidum causes:
a. AIDS
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19. Progesterone secretion diminishes and its supporting 28. If the queen bee lays eggs that are not fertilised, they
HHFWRQWKHVSRQJ\HQGRPHWULXPLVUHGXFHG7KLVLV will develop into:
related with: a. Worker bees
D)RUPDWLRQRI*UDDȴDQIROOLFOH b. Drones
b. Degeneration of corpus luteum c. Queen bees
c. Rise in level of LH d. Larvae
d. Implantation of zygote
:KDWLVWKHNH\GLHUHQFHEHWZHHQVSHUPDWRJHQHVLV
20. Oxytocin performs its function on: and oogenesis:
a. Perimetrium a. Spermatogenesis results in only only 1 sperm, oo
b. Endometrium genesis result in 4 eggs
c. Myometrium b. Spermatogenesis results in 2 sperm, oogenesis
d. All of the above result in 1 eggs
c. Spermatogenesis results in 4 sperm, oogenesis result
7KHSURGXFWLRQRIDVOLJKWO\DFLGLFȵXLGZLWKFLWUDWHDV in 1 eggs
the main nutrient source is the function of: d. Spermatogenesis results in 8 sperm, oogenesis
a. Bulbourethral gland result in 4 eggs
b. Cowper’s gland
c. Seminal vesicle 30. Regarding the structure of female reproductive sys-
d. Prostate gland tem, oviduct opens into:
a. Vagina
22. In the human male reproductive system, which of the b. Ureter
following structures is unpaired? c. Urethra
a. Seminal vesicle d. Uterus
b. Cowper’s gland
c. Prostate gland
d. Vas defrenes
23. Each testes is divided into how many lobules? Your Score: ____ / 30
a. 100-150
b. 150-200
c. 250-300
d. 350-400
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becomes female and later transitions into a male, the
process is called:
a. Protogyny
b. Protandry
c. Parthenogenesis
d. Polygyny
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A B C D
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8 NAME
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FATHER’S NAME
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11 ROLL NO.
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ROLL NO. IN WORDS
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QUESTION PAPER ID
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19 EXAMINATION CENTER
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DEPUTY SUPT SIGN
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24 INSTRUCTIONS
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