School Grade Level 10

Student Teacher Learning Science 10

Area
Teaching Time Quarter 3rd
I. Objectives
A. Content Standards
B. Performance Standards
C. Learning Competencies/objectives 1. Describe DNA Replication.
2. Identify the key players in DNA
Replication.
3. Explain the process of DNA
Replication
a. Describe DNA Replication
b. Identify the key players in
DNA Replication.
c. Explain the process of
DNA Replication.

II. Content/Subject Matter DNA Replication

III. Learning Resources
A. Teacher’s Guide Pages
B. Learner’s Material Pages
C. Textbook Pages
D. Additional Materials from Learning Resources
IV. Procedures 5E’s
Teachers’ Activities Learners’ Activities

A. Preliminaries
a) Greetings

Good Morning Class!

Good Morning Ma’am!
How are you today?
Answers may vary
Kindly stand for the opening prayer.
Denver, kindly lead the opening prayer
Kindly stand for the opening prayer.
Denver, kindly lead the opening prayer.
b) Prayer Students do as told

To start our class, everybody stand

for the prayer. Pleaes lead the prayer
________

c) Classroom Management

Alright, before you have your seats kindly

pick up the pieces under your chairs and
align your chairs properly.

Thank you! You may now have your seats.

Students do as told

d) Checking of attendance

Who is your class monitor?

How many are absent today? Answer may vary
 B. ENGAGE
ACTIVITY TITLE: 4 PICS 1 WORD

Let’s play a game called 4 Pics1word. I will present

four pictures and then you are going to guess what
word fits with 4 photos.

Are you ready?

Yes Ma’am!

Time Is Up! The teacher will gather DNA

the work of the
pupils and she will check if each group
got the correct answer

Photo presented

Copy

Yes! You have guessed it right.

Genetic Information ma’am
Now, when you hear about the word DNA what comes
to your mind?

Yes, that’s correct! It has something to do on how we

become who we are.

C. EXPLORE
Now, let’s have an activity. First, I have to divide this
class into two groups.

This row will be group 1, the second row will be group

2.

Our activity is called “ DNA MAKES DNA ” DIRECTION:

In 3 minutes, match the 4
Everybody Read the Directions nitrogenous bases to their
perfect pair and paste it on
DIRECTION: the bondpaper. Answer the
In 3 minutes, match the 4 nitrogenous bases to guide questions and report it
their perfect pair and paste it on the bondpaper. in the class.
Answer the guide questions and report it in the
class.
 This are your materials and together with it is the
procedure of the activity. After performing the
activity answer the following questions. Yes Ma’am!

Alright, are you ready class?

Your 3 minutes starts now!

Time’s up!
Group 1 are presenting
Now, let us see your presentations. Let us start
with group number 1
Students are clapping

Group 2 are presenting

Let’s give 5 claps for group 1
Students are clapping
Okay, next group.

Wow! That was a fun presentation. Let’s give the

group 2, 5 claps.

D. EXPLAIN It is about Copying genetic

information Ma’am
Okay, what do you think is the idea behind the pictures I
flashed earlier? No Ma’am!

Do you want to know how DNA Replicates?

This morning we will explore how

DNA replicates. Before that lets have
If that’s the case be with me this morning as we will
discuss about DNA REPLICATION.
a. Describe DNA Replication
b. Identify the key players in
At the end of this lesson you are expected to attain this
DNA Replication.
following objectives:
c. Explain the process of
DNA Replication.
Everyobody read

Let us know more about DNA Replication class. Students are listening

In 1953, James Watson and Francis Crick worked

out
that DNA is a double helix.

As you can see in this picture class this is the

summary of what happen In DNA Replication.

DNA REPLICATION

DNA Replication is the process of making a copy

of the genetic information contained in DNA. This
process is necessary for cell division and the They fasten the chemical reaction
transfer of genetic information from one generation in our Body Ma’am!
to the next.

So DNA Replication class is simply producing two

identical DNA molecule. Helicase, Primase, DNA Polymerase
and Ligase
The strand of our DNA molecule class made of four
chemical bases, these are letters A, T, C and G.

In the process of DNA replication, we have what we

call the key players.

When you hear the word enzyme, what comes in

your mind?

Okay, we need this enzymes in order to do

Helicase- (the unzipping
something to DNA.
enzyme)
 an enzyme that
What are those key players in DNA Replication?
unzips/separate the
double helix by
breaking the hydrogen
So DNA replication you start with a parent strand
bonds between the
and you come up with two daughters strand which
complementary bases.
are identical to each other.

So the First step in DNA Replication is to separate

the two strand. Replication Fork- very active
area where DNA Replication
Please read takes place.

Helicase- (the unzipping enzyme)

 an enzyme that unzips/separate the double
helix by breaking the hydrogen bonds
between the complementary bases.

Please read

Replication Fork- very active area where DNA Primase (initializer)

Replication takes place.  Serve as a starting
point for DNA
synthesis.
 Makes the small piece
 It is created when DNA helicase unwinds the
 double helix structure of the DNA. of RNA Primer.
So the separated strand now, is providing a
Template for creating a new strand of DNA

Let’s procces to another one, kindly read.

DNA Polymerase (the
Primase (initializer) builder)
 Serve as a starting point for DNA synthesis.
 Makes the small piece of RNA Primer.  An enzyme that
replicates DNA to build
a new strand
 binds with the Primer.

Ligase- (the gluer)

Let’s procces to another one, kindly read.  an enzyme which
connects two strands
DNA Polymerase (the builder) of DNA together.

 An enzyme that replicates DNA to build a

new strand
 binds with the Primer.

Let’s procces to another one, kindly read.

Ligase- (the gluer)

 an enzyme which connects two strands of
DNA together.

To understand more about what really

Happen here, I will show you a video about
The DNA Replication.

https://www.youtube.com/watch?v=TNKWgcFPHqw

So the DNA splits into two separate strands

What causes the split? It is the enzyme helli-
Case.

After that we can see that there nitrogenous

Bases attached to each strand. So it’s not
That easy, there should be one who will start
To attach, and that enzyme is called the
Primase also called as the initializer, it serves
As the starting point of the DNA Replication.
Now the one who build the nitrogenous base
To form a new DNA strand is what we call the Helicase, Primase, DNA Polymerase,
DNA polymerase, that is why is it called the and Ligase
Builder. And that nitrogenouse bases need to
Be glue or strongly attach or something to
A finishing touch the Enzyme Ligase

So those are the functions of the four enzymes

Which we call as the Key Players of the DNA
Replication.

What are those?

Yes?

Once the pairing is done what happens is

 That, the DNA coils back again and after- DIRECTIONS:
Wards there will be now two copies of original In 3 minutes dramatize the
DNA. process of DNA Replication.
There sould someone stand
as the key players. Select 1
E. ELABORATE representative to explain the
Let us have another activity. process of DNA Replication.
With the same group you have. Dramatize the
action taken or the process in DNA Replication.
Students are doing the activity
Everybody Read the Directions

DIRECTIONS:
In 3 minutes dramatize the process of DNA Group 1 are presenting
Replication. There sould someone stand as the key
players. Select 1 representative to explain the Studenst are clapping
process of DNA Replication.
Group 2 are presenting

Students are clapping

Your 3 minutes starts now,

Time’s up!
Students Get ¼ sheet of paper
Let’s start with the Group 1

Let’s give 5 claps to G-1

How about the G-2

ANSWER KEY
Let’s give 5 claps to G-2
1-4

EVALUATION Cytosine

Class, please get one-fourth sheet of paper for we Guanine

will have a shortassessment of what you have
learned today. Please keep your notes, books and Thymine
other unrelated materials on your desk. Only
yourpen and paper needed. Adenine

1-4 Give the 4 nitrogenous bases. (In any order)

5. It is a process of making copies of DNA
5. DNA Replication
TEST II:
Test II
EXPLANATION
1. Answer may vary
1. What is DNA Replication? (2points) 2. Answer may vary
2. Explain how DNA Replication works. (3
points)

ASSIGNMENT
Please get your notebook and write your
assignment.1. In a whole sheet of paper, write the
 importance of DNA Replication.

Prepared by

BANDIALA, PRIEN MAE A.