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CRISPR-Cas9 is a revolutionary gene-editing system that enables precise DNA modifications in various organisms, with applications in agriculture, medicine, and research. However, it raises ethical concerns regarding germline editing and potential unintended consequences, necessitating careful public discourse and regulatory measures. The responsible use of CRISPR is crucial to maximize its benefits for humanity.

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MOHAMED HUSSEIN DOUMBIA
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7 views

Research_Paper_2

CRISPR-Cas9 is a revolutionary gene-editing system that enables precise DNA modifications in various organisms, with applications in agriculture, medicine, and research. However, it raises ethical concerns regarding germline editing and potential unintended consequences, necessitating careful public discourse and regulatory measures. The responsible use of CRISPR is crucial to maximize its benefits for humanity.

Uploaded by

MOHAMED HUSSEIN DOUMBIA
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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CRISPR and the Future of Genetic Engineering

Abstract: An overview of the CRISPR-Cas9 gene-editing system, its role in biotechnology, medical

research, and potential societal risks.

1. Introduction

CRISPR-Cas9 has transformed the field of genetic engineering by providing a simple, accurate, and

efficient method to edit DNA. Derived from bacterial immune systems, CRISPR allows for precise

gene modification in plants, animals, and humans.

2. Mechanism of Action

CRISPR uses a guide RNA to target specific DNA sequences. The Cas9 protein then introduces a

double-strand break, which can be repaired to insert or delete genetic material.

3. Applications

CRISPR is used in agriculture to develop disease-resistant crops, in medicine to treat genetic

disorders like sickle-cell anemia, and in basic research to understand gene function.

4. Ethical and Social Implications

Concerns arise around germline editing, unintended consequences (off-target effects), and the

possibility of "designer babies." Public discourse and regulatory frameworks must keep pace with

technological developments.

5. Conclusion

CRISPR is a powerful tool that will shape the future of biology. Ethical and responsible use is

essential to ensure it benefits all of humanity.

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