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Advantages and Disadvantages

Paper chromatography is a simple, rapid, and cost-effective method for identifying both inorganic and organic compounds with excellent resolving power. However, it has limitations such as handling small sample sizes, being less effective for quantitative analysis, and struggling with complex mixtures. Its applications include separating polar and non-polar compounds, analyzing amino acids, and inspecting pharmaceuticals and food products.

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12 views

Advantages and Disadvantages

Paper chromatography is a simple, rapid, and cost-effective method for identifying both inorganic and organic compounds with excellent resolving power. However, it has limitations such as handling small sample sizes, being less effective for quantitative analysis, and struggling with complex mixtures. Its applications include separating polar and non-polar compounds, analyzing amino acids, and inspecting pharmaceuticals and food products.

Uploaded by

amairasnacks
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOCX, PDF, TXT or read online on Scribd
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Advantages of Paper Chromatography

1) Simple and rapid


2) Paper chromatography necessitates a minimal amount of quantitative material.
3) Paper chromatography is less expensive than other chromatography methods.
4) The paper chromatography method can identify both unknown inorganic and
organic compounds.
5) Paper chromatography takes up little space when compared to other analytical
methods or equipment.
6) Outstanding resolving power

Disadvantages of Paper Chromatography


1) Paper chromatography cannot handle large amounts of sample.
2) Paper chromatography is ineffective in quantitative analysis.
3) Paper chromatography cannot separate complex mixtures.
4) Less Accurate than HPLC or HPTLC

Applications of Paper Chromatography

1. Paper chromatography is specially used to separate a mixture having polar


and non-polar compounds.
2. For separation of amino acids.
3. It is used to determine organic compounds, biochemical in urine, etc.
4. In the pharma sector, it is used to determine hormones, drugs, etc.
5. Sometimes it is also used to evaluate inorganic compounds like salts and
complexes.
6. It is often used to inspect cosmetics and detect contaminants in food and
drink.

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