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Lesson Plan BP404T

The document outlines the lecture plan for a B-Pharm course in Pharmacology I, detailing topics to be covered over the semester, including general pharmacology, pharmacokinetics, pharmacodynamics, and the pharmacology of the peripheral and central nervous systems. It includes specific areas of focus such as drug interactions, adverse drug reactions, and drug discovery processes. Additionally, sample questions related to each topic are provided to aid in student understanding and assessment preparation.

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hashim.khalil2k18
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23 views4 pages

Lesson Plan BP404T

The document outlines the lecture plan for a B-Pharm course in Pharmacology I, detailing topics to be covered over the semester, including general pharmacology, pharmacokinetics, pharmacodynamics, and the pharmacology of the peripheral and central nervous systems. It includes specific areas of focus such as drug interactions, adverse drug reactions, and drug discovery processes. Additionally, sample questions related to each topic are provided to aid in student understanding and assessment preparation.

Uploaded by

hashim.khalil2k18
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOCX, PDF, TXT or read online on Scribd
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SRI SAI RR INSTITUTE OF PHARMACY

NH-91,G. T. ROAD, OPP PHAL MANDI SARSOL


ALIGARH (U. P.) 202001
COURSE B-PHARM Sem.: 4
SUBJECT PHAMACOLOGY I Course BP404T
Code:
NAME OF HASHIM KHALIL AHMAD
FACULTY

Summary of the Lecture Plan


Topic Lectures Hours
Introduction to Pharmacology- Definition, historical 2
landmarks and scope of pharmacology, nature and
I. source of drugs
essential drugs concept and routes of drug 2
General administration, Agonists, antagonists (competitive and
Pharmacology non-competitive),
spare receptors, addiction, tolerance, dependence, 1
tachyphylaxis, idiosyncrasy, allergy.
Pharmacokinetics- Membrane transport, absorption, 2
distribution, metabolism and excretion of drugs

Enzyme induction, enzyme inhibition, kinetics of 1


elimination
II. a. Pharmacodynamics- Principles and mechanisms of 2
General drug action. Receptor theories and classification of
Pharmacology receptors, regulation of receptors.
Drug receptors interactions signal transduction 2
mechanisms, G protein–coupled receptors, ion channel
receptor, transmembrane enzyme linked receptors,
Transmembrane JAK-STAT binding receptor and 3
receptors that regulate transcription factors, dose
response relationship, therapeutic index, combined
effects of drugs and factors modifying drug action.
b. Adverse drug reactions.
c. Drug interactions (pharmacokinetic and 3
pharmacodynamic)
d. Drug discovery and clinical evaluation of new drugs -
Drug discovery phase,

Preclinical evaluation phase, clinical trial phase, phases 2


of clinical trials and pharmacovigilance.
III. a. Organization and function of ANS 1
Pharmacology of
peripheral nervous b. Neurohumoral transmission-transmission and 2
system classification of neurotransmitters.
c. parasympathomimetic, Parasympatholytic, 2
Sympathomimetics, sympatholytic.
d. Neuromuscular blocking agents and skeletal muscle
relaxants (peripheral). 2
e. Local anesthetic agents. 1

f. Drugs used in myasthenia gravis and glaucoma 2

a. Neurohumoral transmission in the C.N.S. special 3


IV. Pharmacology of emphasis on importance of various neurotransmitters like
central nervous system with GABA, Glutamate, Glycine, serotonin, dopamine.
b. General anesthetics and pre-anesthetics 1
c. Sedatives, hypnotics and centrally acting muscle 2
relaxants
d. Anti-epileptics 1
e. Alcohols and disulfiram 1
V. Pharmacology of a. Psychopharmacological agents: Antipsychotics, 2
central nervous system antidepressants, anti-anxiety agents,
b. Drugs used in Parkinsons disease and Alzheimer’s 2
disease.
c. CNS stimulants and nootropics. 1
d. Opioid analgesics and antagonists 1

1
e. Drug addiction, drug abuse, tolerance and dependence.

Major issues or Core aspects to be addressed/covered:


Topic Title - General Pharmacology
Introduction to Pharmacology, historical landmarks and scope of pharmacology
Nature and source of drugs, essential drugs concept
Routes of drug administration

Agonists, antagonists (competitive and non-competitive), spare receptors, addiction, tolerance,


dependence, tachyphylaxis, idiosyncrasy, allergy
Pharmacokinetics- absorption, distribution, metabolism and excretion, and its factors
Enzyme induction, enzyme inhibition, kinetics of elimination

Topic Title- General Pharmacology


Pharmacokinetic and Pharmacodynamic Drug interactions

Types of receptors including G-protein, jak stat, DRC, therapeutic index and parameters
Adverse drug reactions: different types and mechanism
Drug discovery and clinical evaluation of new drugs -Drug discovery phase
Preclinical evaluation phase, phases of clinical trials & pharmacovigilance
Topic Title- Pharmacology of drug acting on peripheral nervous system
Organization and function of ANS, Neurohumoral transmission-transmission and
classification of neurotransmitters
Parasympathomimetic, Parasympatholytic, Sympathomimetics, sympatholytic classifications,
pharmacology of acetyl choline, atropine, adrenaline, beta and alpha blockers, cholinergic and
adrenergic receptors.
Neuromuscular blocking agents and skeletal muscle relaxants
(peripheral) classification and pharmacology of succinyl choline
Local anesthetic agents classification, uses of LA
Drugs used in myasthenia gravis
Glaucoma- types and drugs used in both conditions
Mydriatic and miotic agents
Topic Title-Pharmacology of drug acting on central nervous system
Neurohumoral transmission in the C.N.S like with GABA, Glutamate, Glycine, serotonin,
dopamine.
General anesthetics and pharmacology of lignocaine, drugs used as preanesthetic
Sedatives& hypnotics – classification, pharmacology of barbiturates and benzodiazepines,
mechanism of action of other drugs, barbiturate poisoning, centrally acting muscle relaxants
and their actions
Anti-epileptic classification, pharmacology of phenytoin
Methanol, ethanol and flumazenil, disulfiram
Topic Title- Drugs acting on central nervous system
Psychopharmacological aspects of Antipsychotics, antidepressants, anti-anxiety agents, anti-
manic and hallucinogens and pharmacology.
Parkinsons and Alzheimer’s disease- classification of drugs and its pharmacology

CNS stimulants and nootropics, piracetam


Opioid analgesics and antagonists, opioid receptors, treatment in poisoning
Drug addiction, drug abuse, tolerance and dependence.

Sample Questions
Topic Title- General Pharmacology
Different routes of administrations with advantages and disadvantages
Scope of pharmacology
Metabolism reactions with examples
Enzyme induction and inhibition with examples
Factors affecting absorption
Note on spare receptors
Topic Title- General Pharmacology
Note on types and mechanisms of ADR

Pharmacokinetic drug interactions with examples


Phases of drug discovery and clinical trials
Pharmacovigilance

Topic Title- Pharmacology of drug acting on peripheral nervous system


Cholinergic and adrenergic neurotransmission with diagram
Beta blocker classification, its pharmacology and uses
Skeletal muscle relaxant classification and write down the pharmacology of succinyl choline
Uses of local anesthetics
Myasthenia gravis, Mydriatics and miotics
Topic Title- Pharmacology of drug acting on central nervous
Note on preanesthetic medications

Pharmacology of barbiturates
Pharmacology of benzodiazepines
Ethanol poisoning and its treatment
Topic Title- Pharmacology of drug acting on central nervous
Opioid receptors
Drugs in Alzheimer’s disease
Classification of antiparkinsons disease
Mechanism of action and uses of lithium

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