UDOM lecture 5- 3rd years, April 2023
UDOM lecture 5- 3rd years, April 2023
DISEASES
BY NIMTAZ WALJI
MA-Education, Health Promotion and International Development
BSc (Med) (Hons) Nutrition & Dietetics
BSc Human Biosciences (Physiology & Psychology majors)
Often present with hyperglycemia, excess thirst (polydipsia), frequent urination (polyuria),
significant weight loss, dehydration, electrolyte disturbance, ketoacidosis
Most diagnoses before age of 30yrs but can occur even in older age
Multiple autoantibodies
Usually a fixed basal of long acting + a split bolus dose of short acting with meals but
sometimes also a fixed dosage
• Can adjust into their eating habits and physical activity schedule
• Allows flexibility on when and what to eat
Major determinant of rapid insulin is total carbohydrate per meal *but also affected by other
food groups like protein and fat
Those with fixed insulin- will need day to day consistency in timing and carbohydrate
amounts
Mahan & Escott-Stump, 2008
ISPAD CLINICAL PRACTICE CONSENSUS GUIDELINES, 2018
TYPE 1 DM
DIET PLANNING
Select appropriate meal planning approach
• Other approaches?
Can we incorporate sugar? If yes, how much? What are some challenges of not
incorporating sugar?
CVD diet guidelines? *higher risk of CVD than their age and sex matched youth
Positive impact of metabolic and psychological health and helps with weight
management
Frequent glucose monitoring before, during and after exercise and appropriate
adjustments insulin and dietary intake is CRUCIAL
*Including prior to meals and snacks, at bedtime, and as needed for safety in specific
situations such as exercise, driving, or the presence of symptoms of hypoglycemia
Therefore preventing excess weight gain is desirable. Only aim for normal growth
and development requirements.
≤ 7 (most children)
*less stringent guidelines of 7.5-8%
HbA1c (%) ≤ 7.5 to prevent hypoglycaemia
*<than 6.5% if can be achieved
without significant hypoglycaemia
Maintenance of normal growth and development, maintenance of body weight, preventing acute and chronic
complications
Important considerations for nutritional advice- cultural, ethnic and family traditions, as well as the cognitive
The optimal macronutrient distribution varies depending on an individualised assessment of the young person
Matching of insulin dose to carbohydrate intake on intensive insulin regimens allows greater flexibility in
carbohydrate intake and meal times, with improvements in glycemic control and quality of life.
Mealtime routines and dietary quality are important for optimal glycemic outcomes
Preprandial insulin dosing should be encouraged from diabetes onset for children of all ages
Fixed insulin regimens require consistency in carbohydrate amount and timing to improve glycemic control and
The use of the glycemic index provides additional benefit to glycemic control over that observed when total
Dietary fat and protein impact early and delayed postprandial glycemia
DIABETES IN ADOLESCENTS
ISPAD CLINICAL PRACTICE CONSENSUS GUIDELINES, 2018
Prevention of overweight and obesity in pediatric type 1 diabetes is a key strategy of care and should involve a
family based approach.
Repeated episodes of diabetic ketoacidosis or worsening glycemic control may be a sign of disordered eating
Nutritional advice should be provided on how to successfully manage both regular and unanticipated physical
activity; and how to meet individual goals in competitive sports .
Nutritional management of type 2 diabetes requires a family and community approach to address the
fundamental problems of excessive weight gain, lack of physical activity and the increased risks of
cardiovascular disease.
To enable appropriate matching of carbohydrate intake to the insulin profile, carbohydrate may be measured
in grams, portions or exchanges. A variety of educational tools are available in many countries to assist health
professionals and families understand healthy eating concepts (such as the healthy plate model) and to enable
carbohydrate quantification.
Prevention and management of hypoglycemia, particularly during and after exercise should be discussed.
Drinks high in sugar and foods with high amounts of saturated fat should be generally avoided.
If financial constraints make food scare or erratic, this is an added burden that should be discussed openly and
potential solutions identified.
TYPE 1 DIABETES IN ADOLESCENTS
DIET PLANNING
Nutrition assessment
Initial goal may be to restore and maintain appropriate body weight (4-6weeks)
Nutrient requirements similar to children without diabetes aimed at improving diabetes
outcomes and reducing cardiovascular risk
Hence can use DRI/RDA (Institute of Medicine, 2002)
However, preferable to use diet history considering growth and development are at par
Energy requirements depend on:
Age, physical activity, growth rate, evaluation of height, weight, BMI
Therefore review yearly (minimum)
In most practical cases, more often
Avoid:
Withholding food
Making patient eat without an appetite
Mahan & Escott-Stump, 2008
TYPE 2 DIABETES IN ADOLESCENTS
DIET PLANNING
Highly prevalent in obese youth
Follows a similar progressive pattern as in adult
Focus on
NOTE- all macronutrient distributions are guides only, adjust according to patients individualised
needs- metabolic control, patient previous diet history, dietary preferences etc
DIABETES IN ADOLESCENTS
How to monitor the diabetic goals of growth and development, maintenance of body
weight
Growth charts
Some causes of poor weight gain:
Poor glycemic control
Inadequate insulin
Over-restriction of calories
Other: thyroid abnormalities and malabsorption
Causes of excess weight gain:
Excessive caloric intake
Over-treating hypoglycaemia
Over insulinization
Other: low physical activity, hypothyroidism
Mahan & Escott-Stump, 2008
ADDITIONAL READING
https://diabetesjournals.org/care/article/45/Supplement_1/S208/138922/14-
Children-and-Adolescents-Standards-of-Medical
Perform a 75-g OGTT, with plasma glucose measurement when patient is fasting and at 1 and 2 h, at 24–28 weeks
of gestation in women not previously diagnosed with diabetes.
The OGTT should be performed in the morning after an overnight fast of at least 8 h.
The diagnosis of GDM is made when any of the following plasma glucose values are met or exceeded:
Fasting: 92 mg/dL (5.1 mmol/L)
1 h: 180 mg/dL (10.0 mmol/L)
2 h: 153 mg/dL (8.5 mmol/L)
Step 1: Perform a 50-g GLT (nonfasting), with plasma glucose measurement at 1 h, at 24–28 weeks of gestation in
women not previously diagnosed with diabetes.
If the plasma glucose level measured 1 h after the load is ≥130, 135, or 140 mg/dL (7.2, 7.5, or 7.8 mmol/L,
respectively), proceed to a 100-g OGTT. If ≥200mg/dL- diagnosed and no need for further testing.
Step 2: The 100-g OGTT should be performed when the patient is fasting.
The diagnosis of GDM is made when at least two* of the following four plasma glucose levels (measured fasting
and at 1, 2, and 3 h during OGTT) are met or exceeded (Carpenter-Coustan criteria [244]):
Fasting: 95 mg/dL (5.3 mmol/L)
1 h: 180 mg/dL (10.0 mmol/L)
2 h: 155 mg/dL (8.6 mmol/L)
3 h: 140 mg/dL (7.8 mmol/L)
Standards of Medical Care in Diabetes, ADA position statement 2022
GUIDELINES FOR WEIGHT GAIN IN PREGNANCY
Institute of Medicine released these guidelines for weight gain during pregnancy in 2009
WEIGHT Prepregnancy BMI Total weight gain 1st Trimester gain 2nd and 3rd Trimester
weekly gain
Underweight < 18.5 12.7 - 18 kg Calculations assume a 0.45 (0.45-0.59) kg
Normal weight 18.5 – 24.9 11.4 - 15.9 kg 0.5–2 kg weight gain in 0.45 (0.36-0.45) kg
*Underweight < 18.5 22.6 - 28.1 kg *adapted from a different reference source
Normal weight 18.5 – 24.9 16.8 - 24.5kg
American Diabetes
All pregnant women should
Association. 14.
eat a minimum of 175 g
The food plan should be Management of Diabetes in
total CHO and 28 g fiber.
based on a nutrition Pregnancy: Standards of
American Diabetes For women with GDM, the
assessment with guidance Medical Care in Diabetes.
Association amount and type of CHO
from the Dietary Reference 2019 Diabetes Care
will impact glucose levels,
Intakes. 2019;42(Suppl. 1): S165–
especially post-meal
S172|https://doi.org/
excursions.
10.2337/dc19-S014
• Preventing ketosis
Individualised meal plan designed based on
• Fasting ketones
• Apetite
• Weight gain
Alternate methods for calculating energy requirements in pregnancy range from 20-35kCal/kg
pregravid IBW to 25-35kCal/kg present pregnant body weight, including for obese women
(Gabbe and Graves, 2003; Gunderson, 2004).
GESTATIONAL DIABETES
CALCULATIONS
Composition:
35-45% complex high fibre CHO (but meet at least the DRI for pregnancy of 175g/day)
Important nutrients:
Calcium : 3 milk portions
Folate: emphasise good food sources
Iron: emphasise food sources and use supplement when needed
GESTATIONAL DIABETES
OTHER
Encourage gentle exercise for weight management and glucose control (with
nutrition)
Brisk walk after meals often recommended
Breast feeding encouraged- can reduce post partum insulin requirements, improve
metabolic profile of the mother, may retard future onset of diabetes (McManus, 2001)
May present as
• Feeling shaky
• Irritability or impatience
• Confusion
• Fast heartbeat
• Hunger
• Nausea
• Feeling sleepy
• Blurred/impaired vision
• Headaches
• Seizures
Eating a different meal than usual (e.g. a veg soup in place of a full dinner meal)
Alcohol
1 tbs of sugar/honey
1 cup of milk
HYPERGLYCEMIA
May present as
Frequent urination
Tiredness
Dry mouth
Blurry vision
Increased thirst
Shortness of breath
Causes
Infection/illness
TZ NCD Guideline, 2013
DIABETIC KETOACIDOSIS (DKA)
From hyperglycemia
Acute illnesses such as colds, diarrhoea if managed inappropriately can lead to DKA
Caused by insufficient insulin - leads dependence on fat for energy - ketones are
formed
Acidosis- caused by excess production and less use of acetoacetic acid and 3-B-
hydroxybutyric acid from fatty acids
• Electrolyte imbalance
Symptoms
• Polyuria
• Polydipsia
• Hyperventilation
• Dehydration
• Fatigue
Treatment
• Supplemental insulin
• Medical monitoring
Mahan & Escott-Stump, 2008
LONG-TERM COMPLICATIONS
Macrovascular diseases - metabolic syndrome, CVD
Set nutritional goals and objectives Growth and development, weight management, tight blood
glucose control
Calculate requirements DRI/RDA, diet hx, requirement for wt gain or loss
Using exchanges, convert to a diet TO MATCH INSULIN SCHEDULE
plan keeping diet hx in mind
Counselling
Follow up- monitoring and Growth and development, menstruation, weight, dietary
evaluation compliance, blood sugars
TUTORIAL 2- TYPE 1 DM
A 16yr old girl of Indian origin was recently diagnosed with type 1 DM. She had presented with an episode of DKA. On
taking her history, it was discovered that she had lost 12% of her body weight in the last 6 months. Her diet hx showed
her intake to be 2000kcal/day with 70% used in form of carbohydrates (mostly refined). Her weight on presentation
was 54kg, height was 163.5cm
1400/5900
1600/6700
1800/7600
2000/8400
2200/9200
2400/10000
TUTORIAL 4- GESTATIONAL DIABETES
Prepare a standard exchange table for the following caloric values using a
macronutrient distribution of 45% carbohydrates, 20% protein and 35% fat
1400/5900 3 6 3 6 2 3
1600/6700 3 7 4 8 2 3
1800/7600 3 8 5 9 2 3
2000/8400 3 10 6 10 2 3
2200/9200 3 11 7 10 2 3
2400/10000 3 13 7 11 3 3
REFERENCES
American Diabetes Association Professional Practice Committee; 2. Classification and Diagnosis of Diabetes:
Standards of Medical Care in Diabetes—2022. Diabetes Care 1 January 2022; 45 (Supplement_1): S17–S38. https://
doi.org/10.2337/dc22-S002
American Diabetes Association; Standards of Medical Care in Diabetes—2020 Abridged for Primary Care Providers.
Clin Diabetes 1 January 2020; 38 (1): 10–38. https://doi.org/10.2337/cd20-as01
Lifestyle and Non-communicable Diseases. Symptoms, Effects and Prevention. Education to the Community, 2014-
https://hssrc.tamisemi.go.tz/storage/app/uploads/public/5cf/a3d/8cd/5cfa3d8cd261b544310595.pdf
Mahan, L. K., Escott-Stump, S., & Krause, M. V. (2008). Krause's food & nutrition therapy. 12th ed. Philadelphia, Pa. ;
Edinburgh: Elsevier Saunders
Mayer-Davis EJ, Kahkoska AR, Jefferies C, Dabelea D, Balde N, Gong CX, Aschner P, Craig ME. ISPAD Clinical Practice
Consensus Guidelines 2018: Definition, epidemiology, and classification of diabetes in children and adolescents.
Pediatr Diabetes. 2018 Oct;19 Suppl 27(Suppl 27):7-19. doi: 10.1111/pedi.12773. PMID: 30226024; PMCID: PMC7521365.
Mustad VA, Huynh DTT, López-Pedrosa JM, Campoy C, Rueda R. The Role of Dietary Carbohydrates in Gestational
Diabetes. Nutrients. 2020;12(2):385. Published 2020 Jan 31. doi:10.3390/nu12020385
http://guidelines.diabetes.ca/cpg
https://www.worlddiabetesfoundation.org/sites/default/files/NCD%20Desk%20Guide%20Tanzania.pdf
https://www.diabetes.org/healthy-living/medication-treatments/blood-glucose-testing-and-control/hypoglycemia