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Call for proposal_0

The DBT BIRAC Joint Call for Proposals invites applications for establishing Biofoundries and Biomanufacturing Hubs to support biomanufacturing in various sectors, including bio-based chemicals and climate-resilient agriculture. Proposals can be submitted by academia, companies, and NGOs, with eligibility criteria and required documentation outlined for each category. The deadline for submission is June 30, 2025, and funding will be based on the proposed activities as per the Implementation Plan.

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16 views8 pages

Call for proposal_0

The DBT BIRAC Joint Call for Proposals invites applications for establishing Biofoundries and Biomanufacturing Hubs to support biomanufacturing in various sectors, including bio-based chemicals and climate-resilient agriculture. Proposals can be submitted by academia, companies, and NGOs, with eligibility criteria and required documentation outlined for each category. The deadline for submission is June 30, 2025, and funding will be based on the proposed activities as per the Implementation Plan.

Uploaded by

gandurik
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© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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DBT BIRAC Joint Call for Proposals on मूल ांकुर Bioenablers: Biofoundries and

Biomanufacturing hubs under BioE3 Policy

1. INTRODUCTION:

Recognizing the potential of Biomanufacturing to power green growth, the


Department of Biotechnology (DBT), Govt. of India has undertaken an initiative
on Fostering High Performance Biomanufacturing. Proposals are invited for
setting up of Biofoundries (for early scaling-up of proof-of-concepts) and
Biomanufacturing Hubs (shared pilot-scale and pre-commercial-scale facilities) to
support research, innovation and scale up in the following thematic
sectors/subsectors:

(i) Bio-based chemicals, Bioplastics, Active Pharmaceutical Ingredients


(APIs),and Enzymes
(ii) Functional Foods and Smart Proteins

(iii) Precision Biotherapeutics (monoclonal antibodies, mRNA therapeutics, cell &


gene therapy)

(iv) Climate resilient agriculture(agri-biologicals)

(v) Biofuels and Carbon capture

(vi) Futuristic marine and space research

The applications may be submitted either solely or in partnership by 1.Academia,


2. Company/LLP 3.Societies /Trust/ Non-Government Research Organisations/
Foundation and 4.Start-ups. Support is envisaged for co-development
of Biofoundries and Biomanufacturing hubs as programmatic research support for
scaling-up and biotech product development through biotechnological approaches.
These Biofoundries and Biomanufacturing hubs are expected to provide research
resources and scale-up support to advance in-house research projects as well as
provide services to other organizations, biotech start-ups, SMEs, and industries.

The funding mechanisms for the proposed activities will be as per the
‘Implementation Plan’ (Annexed).

2. SCOPE OF THE CALL:

Proposals for seeking support to establish Biofoundries and Biomanufacturing


Hubs should clearly indicate anyone of the following categories:

A) Using existing facilities

B) Augmenting existing facilities

C) Setting up of new facilities.

The detailed proposal should also highlight the following but not limited to:
i. Available facilities and resources
ii. Biological systems and processes
iii. Product portfolios
iv. Demonstrated experience of setting up such facilities and enabling access to Start-ups (for
projects in PPP mode
v. Modalities of engagement and business model to sustain the proposed facility
vi. Resource Commitments
vii. Any other relevant points

3. MODE OF SUBMISSION:

Proposals may be submitted by both Academia and Industry applicants, either


independently or as a collaborative project.
a. For proposals from Academia / Research Institutions : Interested applicants should
submit the proposals in the prescribed format duly forwarded by the executive head of
the institution through the Departments ePromis portal (www.dbtepromis.nic.in)
b. For proposals from Industry and Industry-Academia collaboration: interested applicants
should submit the proposals in the requisite format duly forwarded by the executive
head of the company/ LLP/ Institution by logging to the BIRAC website
(www.birac.nic.in)

4. ELIGIBILITY:
Following documents need to be submitted by the entity during submission of
detailed proposal (whichever is applicable):

A. Companies

a) Incorporation certificate

b) b. CA/CS certified share holding pattern as per BIRAC format (Companies having
a minimum of 51% Indian share holding/individuals holding Indian passports are
only eligible) mentioning UDIN number

c) Details regarding in-house R&D facility, if any; or Incubation Agreement with


recognized Incubator.

d) Audited financial details of latest last three financial years,

e) Copy of passports of the share holders if required (in support of 51% eligibility
criteria)

B. Limited Liability Partnership

a) Incorporation Certificate

b) Partnership deed; CA/CS certified certificate which states that minimum


half of the partners are Indian citizens mentioning UDIN number.

c) Copy of passports of Indian partners/subscribers

d) Research mandate/details regarding in-house R&D facility, if any


incubation agreement

e) Audited financial details of last three financial years.


Companies/LLP if recommended have to provide a declaration stating that
Company/LLP is not in default to BIRAC OR any other organization. Further
there are no Legal Proceedings going against the applicant

C. Indian Institution/ universities/ public/ private research organization


a) Affiliation / registration certificate or statute reference for establishment
b) Details regarding in-house R&D facility, if any
c) If the institution/public research organization are registered under/as Society or
Trust, then they have to submit the documents as mentioned for trust/society

D. Society/ Trust/ NGO / Foundation


i) Society
a) Society Registration Certificate
b) Bye laws of society
c) Details regarding in-house R&D facility, if any
d) CA certificate (supporting the fact that half of the members of the society
are Indian citizens) mentioning UDIN number

ii) Trust
a) Trust deed and Registration Certificate
b) Details regarding in-house R&D facility, if any
c) CA certificate (supporting the fact that half of the trustees are Indian Citizens)
mentioning UDIN number

iii) NGO/ Foundation


a) For NGO, or Research Foundation, submission of proper
registration/accreditation from a government body is mandatory like UGC
affiliation certification AICTE,CSIR/DSIR/SIRO certificate / Byelaws of
society/ Trust Deed etc whichever is applicable

iv) Startups
The company must be no more than10 years old from the date of incorporation at the
time of closing the call other documents required:

I. Expression of Interest (EOI), MOU or support letters as scanned copies executed on


relevant Letter Heads to show the mutual partnering arrangements in case of
collaborating Project/ Project.
II. Documents related to the conveyance of legal interests in the background
technology/IP.

5. INTELLECTUAL PROPERTY GOVERNING FRAMEWORK


Existing guidelines of DBT and BIRAC will be followed.

6. OPERATIONAL MODALITIES

 Implementation plan may be referred for upper cap on funding and details on
applicant’s contribution for biofoundries and biomanufacturing hubs

 Budget heads to be funded by BIRAC/DBT would include Non-


recurring (refurbishing, renovation, equipment, accessories etc),
Manpower, Consumables (repair and maintenance of equipment,
chemicals, labware, etc.), Travel, Contingency, C o n d u c t i n g Training
& workshops and Outsourcing. Any kind of land/construction cost will
not be considered under project cost.
 As per clause 3.1 of the Implementation plan
 For Biofoundry: A list of technologies proposed to be scaled-up
must be provided along with their PoC. The biofoundry must
also support projects by external users, the budget for which
shall be provided by the biofoundry as per the implementation
plan.
 For Biomanufacturing hubs: a list of technologies proposed to be scaled-up
is to be provided. In-house technologies are also to be mandatorily included
in the list provided. PoC/validation data available for such technologies
need to be provided
 The proposal should be accompanied by a brief description on how the biofoundry/
biomanufacturing hub would generate revenue and plan for cash flow projections.
The business plan is mandatory for the biomanufacturing hub and biofoundry.
 Facilities developed/ operationalized through this programme should be accredited
by a reputed accreditation agency i.e. Good Laboratory Practice (GLP), National
Accreditation Board for Testing and Calibration Laboratories (NABL) etc, if
required.
 The facilities developed/ operationalized through this programme should adhere to
relevant regulatory compliances, environmental authorizations and appropriate
approvals. Proposals that have already secured the relevant clearances or are close
to obtaining them will be prioritized.
 BIRAC/DBT may reach out to the PI if further information is required to consider
the proposal as complete.

7. OTHER REQUIREMENTS AND CRITERIA ARE RELEVANT TO SPECIFIC


CATEGORY AS FOLLOWS:
Category A & B. Development of biofoundries/ biomanufacturing hubs using existing
facilities or augmenting existing facilities
 The applicant seeking BIRAC support for augmenting the existing facility should
have an operational facility at the time of application.
 The applicant should have proven track record in providing services to the startups/
researchers.
 The applicant should have adequate expertise and infrastructure to support
biomanufacturing activities
 The applicant should preferably have an existing ISO9001/2015 certified
facility and ISO 14001certification
 The applicant should give commitment for developing cataloguing and
data management capabilities
Duration: Project duration will be upto 2 years. Extent of funding will depend on the
proposed activities and will be in alignment with the “Implementation Plan for the
Biomanufacturing and Biofoundry Initiative” attached at ANNEXURE-1.
8. USAGE AND ACCESS TO RESOURCES / FACILITIES/ PLATFORMS

 The Facility supported under the Biofoundry/ Biomanufacturing


programme should provide access to its high-end equipment and
infrastructure to entrepreneurs and any public/private entities to scaled-up
their innovations. Once established, their websites are expected to reflect
Infrastructure facility usage forms with well-defined usage charges terms
and conditions.

 The website of the Biofoundry/Biomanufacturing hub shall host a well-


defined link for the facility enumerating the details of user charges, terms
& conditions, mode of application and timelines for the decision on the
applications.
 The user charges shall be separately defined for different categories viz. Research
Institutes, Universities (central, state, private), colleges and start-up/Entrepreneurs

9. PROPOSAL FORMAT AND SUBMISSION


Proposals maybe submitted by both Academia and Industry applicants, either
independently or as a collaborative project
 For proposals from Academia/Research Institutions: The application must be
submitted as per the prescribed format duly forwarded by the Head of the
institution through the Department’s e-ProMIS portal (www.dbtepromis.nic.in).
 For proposals from Industry and Industry-Academia collaboration: The
application must be submitted as per the prescribed format duly forwarded by the
Head of the Company/Institution by logging to the BIRAC website
(www.birac.nic.in).

10. ACKNOWLEDGEMENT
Acknowledgement of DBT/BIRAC support: Acknowledge the assistance of DBT/BIRAC
while publishing, marketing the resultant Product or presenting in any manner the details
of the Project, its progress or its success along with the “Disclaimer” that reference there
into any specific commercial product, process, views or service by tradename, trademark,
manufacturer, or otherwise does not necessarily constitute or imply its endorsement,
recommendation, or assuming liability of any sort by the BIRAC. Use of DBT/BIRAC
logo is not permitted without written approval.

11. DISCRETION
DBT/BIRAC shall reserve the discretion on determination of sanction of funding and
processes as per its standard norms and such determination shall be final. The selection
process is not open to review.

12. CONTACT INFORMATION


The programme shall be governed by the relevant Government/ DBT approval, DBT
orders, corresponding call of proposals, project GLA and the BIRAC norms
Contact Information: Further information can be obtained at www.dbtindia.gov.in and
www.birac.nic.in
Contact person from DBT
Dr. Kalaivani Ganesan, Scientist ‘F’, DBT
Email: [email protected]
Contact person from BIRAC
1. Dr. Shilpi Gupta, Deputy General Manager, Technical,
BIRAC Email: [email protected]
2. Dr. Prachi Kaushik, Senior Manager, Investment, BIRAC Email: [email protected]

Last date for submission of proposals is 30th June, 2025

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