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GENETICS LEC

The document discusses various genetic dental disorders, particularly focusing on Down Syndrome and its implications for oral health, including gingival inflammation and delayed tooth eruption. It outlines treatment and management strategies such as oral hygiene education and antimicrobial therapies. Additionally, it highlights the effects of periodontal disease and malocclusion in individuals with genetic anomalies, emphasizing the need for tailored dental care.

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2 views1 page

GENETICS LEC

The document discusses various genetic dental disorders, particularly focusing on Down Syndrome and its implications for oral health, including gingival inflammation and delayed tooth eruption. It outlines treatment and management strategies such as oral hygiene education and antimicrobial therapies. Additionally, it highlights the effects of periodontal disease and malocclusion in individuals with genetic anomalies, emphasizing the need for tailored dental care.

Uploaded by

051276
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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GENETICS LEC  Gingival Inflammation

 Congenital Missing Incisors


DOWN SYNDROME
 Periodontitis in Permanent
 Trisomy 21 Dentition
 Caused by an extra
TREATMENT AND MANAGEMENT
chromosome
 3 chromosomes at position 21  Oral Hygiene Education
 Chromosome 21 (acrocentric)  Antibacterial Mouthwash
 Antimicrobial Photodynamic
ROLE OF ACROCENTRIC
Therapy
CHROMOSOME IN GENETIC
 Scanning and Root Planning
DENTAL DISORDERS
 Systemic and Local Antibiotics
 Chromosomal rearrangements  Probiotics, Prebiotics,
and structural variations. Symbiotics
 Syndrome with oral
CHROMOSOMAL DELETION IN
manifestation.
ECTODERMAL DYSPLASIA
 Gene dosage effect.
 Group of genetic disorders
DELAYED TOOTH ERUPTION
affecting ectodermal structures.
FACTORS EFFECTS  Commonly involves skin, hair,
teeth, nails, sweat glands.
Down Syndrome Delayed  Most common type: X-linked
Eruption
Hypohidrotic Ectodermal
Congenital Hypodontia
Dysplasia (XLHED)
Anomalies
 Mutations/deletions in the EDA
Slow Cellular Persistence of
Growth Rythm Primary Teeth gene on X chromosome.
Poor Peripheral Bruxism DENTAL IMPLICATIONS
Circulation
Delayed Timing Enlarged Tongue  Hypodontia
and Sequence  Anodontia
 Peg-shaped or conical teeth
 Delayed tooth eruption
MALOCCLUSION

FACTORS EFFECTS

Delayed Tooth Difficulty in


Eruption Speaking
Jaw and Tooth Difficulty in
Size Eating
Discrepancies
Oral Habits Pain and
Discomfort,
Periodontal
Disease

PERIODONTAL DISEASE

FACTORS EFFECTS

Immune Factors Pain and


Discomfort
Polymorphonucle Tooth Loss
ars Defects
T Cells Nutritional
Malfunction Issues
Oro Facial Social
Features Implications
Poor Oral
Hygiene

PERIODONTAL DISEASE IN DOWN


SYNDROME

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