Crushable and non-crushable oral dosage forms

Common brand
Drug name Strength Dosage form Administration details
name

Acarbose Glucobay® 50mg, 100 mg Tablet Tablet can be crushed

Acetazolamide Diamox® 250 mg Tablet Disperse tablet in water
Open the capsules immediately before use and
take with food. Women of childbearing age
Acitretin Neotigason® 10 mg, 25mg Capsule
should not be exposed to the powder if capsules
are opened
Acyclovir Zovirax® 200mg, 400 mg Tablet Acyclovir 200 mg/5 ml suspension available
Do not crush. Disperse in 100 ml of water, stir
20mg, 30mg,
Afatinib Giotrif® Film coated tablet occasionally up to 15mins until it is broken into
40 mg
small particles

Wear a mask and gloves. Open the capsule and

Alectinib Alecensa® 150 mg Capsule
disperse the contents in water.

Agomelatine Valdoxan® 25 mg Tablet No information available on crushing

Alendronate sodium Fosamax® 70 mg Tablet Do not crush
0.25 mcg, Opening of capsule not recommended.
Alfacalcidol One Alpha® Capsule
Alfacalcidol oral drop 2 mcg/ml available
1 mcg
Alfuzosin SR Xatral SR® 5 mg Tablet Do not crush
Alfuzosin XL Xatral XL® 10 mg Tablet Do not crush
Allopurinol Zyloric® 100 mg Tablet Disperse tablet in water

Alogliptin/Pioglitazone Oseni® 25 mg/15 mg Tablet Do not crush

Scored and dose can be halved. Disperse tablet

Amantadine sulphate PK Merz® 100 mg Tablet
in water
Amiloride 5 mg Tablet Tablet can be crushed

Amiloride/
Moduretic® 5 mg/50 mg Tablet No information available on crushing
Hydrochlorothiazide

Amiodarone Cordarone® 200 mg Tablet Tablet can be crushed

100 mg, 200 mg, Scored and tablet can be halved. Crush the tablet
Amisulpride Solian® Tablet
400 mg and mix with water.

Amitriptyline 10 mg, 25 mg Film coated tablet Tablet can be crushed

Amlodipine Norvasc® 5 mg, 10 mg Tablet Tablet can be crushed

Amlodipine/ 5 mg/160 mg,
Exforge® Tablet No information available on crushing
Valsartan 10 mg/160 mg
Amoxycillin Amoxil® 250 mg Capsule Amoxycillin suspension 125mg/5ml available
Amoxycillin 375mg,
Augmentin® Tablet Augmentin syrup 457 mg/5ml available
/Clavulanic Acid 1000 mg
250 mg,
Ampicillin Capsule Capsule can be opened
500 mg
Ampicillin/
Unasyn® 375 mg Film coated tablet No information available on crushing
Sulbactam

PYNEH Pharmacy Department

 Common brand
Drug name Strength Dosage form Administration details
name

Open the capsule and disperse the contents in

Anagrelide Agrylin® 0.5 mg Capsule
water.
Anastrozole Arimedex® 1 mg Film coated tablet Wear a mask and gloves. Disperse tablet in water

Apixaban Eliquis® 2.5 mg, 5 mg Tablet Tablet can be crushed

125 mg/80 mg/

Aprepitant Emend® 80 mg
Capsule Do not open capsule

Normal tablet can be crushed, mixed with water

2 mg,5 mg,
Aripiprazole Abilify® Tablet and taken immediately. Some excipients are
10 mg, 15 mg
insoluble in water and may float to the surface

Ascorbic acid
100 mg Tablet Dipserse tablet in water
(Vitamin C)
Aspirin 80 mg Tablet Tablet can be crushed
Atenolol Tenormin® 50 mg, 100 mg Tablet Tablet can be crushed
10 mg, 20 mg,
Atorvastatin Lipitor® Film coated tablet Disperse tablet in water
40 mg
Immunosuppresant. Wear a mask, gloves and
Azathioprine Imuran® 25 mg, 50 mg Tablet glasses. Disperse the tablet in water in an oral
dispenser. The tablet will disperse within 5 mins.
Azithromycin Zithromax® 250 mg Tablet Azithromycin 200 mg/5 ml suspension available
Baclofen Lioresal® 10 mg Tablet Baclofen 5 mg/ml suspension available
COVID-19 Emergency Use Authorization only
Unable to swallow whole tablets:
Place 4mg tablet in a container with
Baricitinib Olumiant® 4mg Film coated tablet
approximately 10 mL (5 mL minimum) of room
temperature water and disperse by gently
swirling the tablet(s)
Benzhexol Artane® 2 mg Tablet Disperse tablet in water
Betahistine Mesylate Merislon® 6 mg Tablet Tablet can be crushed
Potent anti-androgen. Wear a mask and gloves.
® Crush the tablet to a fine powder and mix with
Bicalutamide Casodex 50 mg Film coated tablet
water.
Biotin 5 mg Tablet Tablet can be crushed
Bisacodyl Dulcolax® 5 mg Enteric coated tablet Do not crush tablet
Bisoprolol Concor® 2.5 mg, 5 mg Tablet Tablet can be crushed
Bisoprolol/ 2.5mg/6.25mg
Lodoz ® Film coated tablet Crushing of tablet not recommended
Hydrochlorothiazide 5 mg/6.25 mg
Bromhexine Bisolvon® 8 mg Tablet Bromhexine 4mg/5ml elixir available
Bromocriptine Parlodel® 2.5 mg Tablet Disperse tablet in water
Scored and can be halved. Disperse tablet in
Bumetanide Burinex® 1 mg Tablet
water
Bupropion XL Wellbutrin XL® 150 mg Tablet Do not crush
Buspirone Buspar® 10 mg Tablet Disperse tablet in water

PYNEH Pharmacy Department

 Common brand
Drug name Strength Dosage form Administration details
name

Cabergoline Dostinex® 0.5 mg Tablet Tablet can be crushed

Caffeine/Ergotamine
Cafergot® Tablet No information available on crushing
tartrate
Liquid filled capsule, measure the oral liquid
0.25 mcg,
Calcitriol Rocaltrol® Capsule medicine with a marked measuring spoon, oral
0.5 mcg
syringe, or medicine cup
Calcium carbonate 1 gm Tablet Tablet can be crushed
Calcium carbonate +
1 gm + 800 IU Tablet Tablet can be crushed
Vitamin D
Candesartan Blopress® 8 mg, 16 mg Tablet Disperse tablet in water
Cytotoxic agent. Wear a mask, gloves and
glasses. Disperse the tablet in 20-50ml of water
150 mg,
Capecitabine Xeloda® Film coated tablet or fruit juice(not grapefruit juice). Shake gently
500 mg
for up to 15mins or until the tablet has evenly
dispersed.
Captopril Capoten® 25 mg Tablet Tablet can be crushed

Carbamazepine Tegretol® 200 mg Tablet Carbamazepine 100 mg/5ml suspension available

Carbamazepine CR Tegretol CR® 200 mg Tablet Scored and can be halved. Do not crush

Carbidopa/ 25 mg/100 mg,

Sinemet® Tablet Tablet can be crushed
Levodopa 25 mg/250 mg
Controlled release
Carbidopa/Levodopa CR Sinemet CR® 50 mg/200 mg Do not crush
tablet
Carbimazole 5 mg Tablet Tablet can be crushed
3.125 mg,
Carvedilol 6.25 mg, Tablet Disperse tablet in water
12.5 mg, 25 mg

Cefuroxime Zinnat® 250 mg Tablet Cefuroxime 125 mg/5 ml suspension available

Capsule contents may be added to 1 level
teaspoon of cool or room temperature
200 mg, 400 applesauce and ingested immediately with
Celecoxib Celebrex® Capsule
water. The sprinkled capsule contents on
mg
applesauce mixture is stable for up to 6 hours if
refrigerated
Open the capsule and disperse the contents in
Cephalexin Keflex® 250 mg Capsule
water.
Cetirizine Zyrtec® 10 mg Tablet Cetirizine 1 mg/ml oral solution available
Cetirizine/ Prolonged release
Zrytec D® Do not crush or cut prolonged release tablet
Pseudoephedrine tablet
Charcoal activated 300 mg Tablet No information available on crushing
Cytotoxic agent. Crushing, chewing and breaking
Chlorambucil Leukeran® 2 mg Tablet
is not recommended.
Chlorpheniramine Piriton® 4 mg Tablet Chlorpheniramine 2mg/5ml elixir available
25 mg,
Chlorpromazine Largactil® Tablet Do not crush
50 mg, 100 mg

PYNEH Pharmacy Department

 Common brand
Drug name Strength Dosage form Administration details
name

Calciferol (vit D2) 0.2 mg/ml (8000 units/ml)

Cholecalciferol (vit D3) 1000 IU(25 mcg) Tablet
drops available
Cilostazol Pletaal® 50 mg Tablet Crush the tablet and mix with water.
Cinacalcet Regpara® 25 mg Tablet No information available on crushing
Cinnarizine Stugeron® 25 mg Tablet Tablet can be crushed
Ciprofloxacin Ciproxin® 250 mg Tablet Disperse tablet in water
Scored tablet and can be halved. Disperse tablet
Citalopram Cipram® 20 mg Tablet
in water
250 mg,
Clarithromycin Klacid® Tablet Clarithromycin 125 mg/5 ml suspension available
500 mg

Clindamycin Dalacin C® 150 mg Capsule Capsule can be opened and mixed with water

Clomiphene citrate 50 mg Tablet Disperse tablet in water

Clomipramine Anafranil® 10 mg, 25 mg Tablet Disperse tablet in water
Clonidine Dixarit® 0.025 mg Tablet Tablet can be crushed
Tablet can be crushed and dispersed in water
Clopidogrel Plavix® 75 mg Tablet
immediately before administration
250 mg,
Cloxacillin Capsule Capsule can be opened
500 mg
Clozapine Clozaril® 25 mg, 100 mg Tablet Tablet can be crushed
Codeine 30 mg Tablet Tablet can be crushed
Colchicine 0.5 mg Tablet Tablet can be crushed
Cotrimoxazole suspension 240 mg/5 ml is
Cotrimoxazole Septrin® 480 mg Tablet
available
Cyanocobalamine 50 mcg, 1000
Tablet Tablet can be crushed
( Vitamin B12) mcg

Cyclophosphamide Endoxan® 50 mg Coated tablet Cytotoxic agent. Do not crush tablet

10 mg,
25 mg,100 mg
Neoral® (Neoral®) Do not remove capsule before use. Capsule
Cyclosporin A Capsule
Ciclosporin-TEVA® 25 mg, 100 mg should be swallowed whole
(Ciclosporin-
TEVA®)
Cyproheptadine Periactin® 4 mg Tablet Cyproheptadine 2 mg/5 ml syrup available
75 mg, 110 Capsule should not be opened, broken or
Dabigatran Pradaxa® Capsule
mg, 150 mg chewed
Daflon® 500 mg Tablet No information on crushing available
Daily one plus® Tablet Tablet can be crushed
Wear a mask and gloves. Open the capsule and
Danazol 200 mg Capsule
disperse the contents in water.
Dapagliflozin 10 mg Film coated tablet Crush the tablet and mix with water.
Dapsone 100 mg Tablet Tablet can be crushed
Wear a mask and gloves. Disperse the tablet in at
20 mg,
Dasatinib Sprycel® Film coated tablet least 5ml of water. The tablet will disperse in 4-7
50 mg,70 mg
mins.

PYNEH Pharmacy Department

 Common brand
Drug name Strength Dosage form Administration details
name

Deferasirox Jadanu® 90 mg, 360 mg Film coated tablet Tablet can be crushed

Deferiprone Ferriprox® 1000 mg Film coated tablet Scored tablet and can be halved

Desmopressin Minirin® 0.1 mg, 0.2 mg Tablet Tablet can be crushed

Desmopressin Minirin Melt® 60 mcg Lyophilisate tablet Tablet is administered sublingually
25mg, 50 mg, Extended release
Desvenlafaxine ER Pristiq® Do not crush tablet
100 mg tablet
Dexamethasone oral solution 2 mg/5 ml is
Dexamethasone Decadron® 0.5 mg, 4 mg Tablet
available
Dexchlorpheniramine Polaramine® 2 mg Tablet Tablet can be crushed
Dexlansoprazole Capsule can be opened and sprinkled on
Dexilant ® 30 mg, 60 mg Capsule
delayed release applesauce. Do not chew and crush granules
Diazoxide 50 mg Tablet Tablet can be crushed
Diclofenac sodium Voltaren® 25 mg Enteric coated tablet Do not crush tablet
Diclofenac sodium SR Voltaren SR® 100 mg Slow release tablet Do not crush tablet
62.5 mcg,
Digoxin Tablet Digoxin 50 mcg/ml elixir available
250 mcg

Dihydrocodeine tartrate DF118® 30 mg Tablet Tablet can be crushed

Controlled release Tablet can be halved. Do not crush controlled

Diltiazem HCL CR Syn-Diltiazem® 30mg
tablet release tablet
Controlled release
Diltiazem HCL CR Herbesser® 60 mg Not recommend to spilt to half and do not crush
tablet
Diltiazem HCL SR Herbesser R® 100 mg, 200 mg Capsule Do not open or chew capsule
Dimenhydrinate Gravol® 50 mg Tablet Dimenhydrinate oral liquid 15 mg/5 ml available
Dimethylpolysiloxane Gasteel® 40 mg Tablet No information available on crushing
Dipyridamole Persantin® 25 mg, 75 mg Tablet Tablet can be crushed
Distigmine bromide Ubretid® 5 mg Tablet Do not crush tablet

Opening of the capsule and draw out liquid is not

Docusate sodium Colace® 100 mg Capsule
recommended as will cause inaccurate dosing

Domperidone Motilium® 10 mg Tablet Tablet can be crushed

Tablet can be crushed. Oral dispersible tablet is

Donepezil Aricept® 5 mg, 10 mg Tablet
available
Oral dispersible Tablet will dissolve in mouth and follow with
Donepezil Aricept Evess® 5 mg, 10 mg
water
tablet
Dothiepin HCL Prothiaden® 25 mg Capsule Open capsule and disperse in water
Dothiepin HCL Prothiaden® 75 mg Tablet Disperse tablet in water
Doxazosin Cardura® 2 mg Tablet Tablet can be crushed
Doxazosin Cardura XL® 4 mg GITS tablet Do not crush tablet
Doxepin Sinequan® 10 mg, 25 mg Capsule Capsule may be opened and mixed with water
Doxycycline hyclate 100 mg Tablet Do not crush tablet
Dronedarone Multaq® 400 mg Tablet No information available on crushing

PYNEH Pharmacy Department

 Common brand
Drug name Strength Dosage form Administration details
name

Open the capsule and disperse the pellets in

Duloxetine Cymbalta® 30 mg, 60 mg Capsule
apple juice.

Edoxaban Lixiana® 30 mg, 60 mg Film coated tablet Tablet can be crushed

Empagliflozin Jardiance® 10 mg, 25 mg Tablet Crush the tablet and mix with water.
Disperse tablet in water immediately prior to
Entacapone Comtan® 200 mg Film coated tablet
administration
Entecavir Hepavance® 0.5 mg Film coated tablet Disperse the tablet in 10-20ml of water.

Eplerenone Inspra® 25 mg, 50 mg Film coated tablet Tablets can be crushed and mixed in apple sauce

Wear a mask and gloves. Disperse the tablet in

® 100 mg, 150
Erlotinib Tarceva Film coated tablet 100ml of water. The tablet will disperse in 10-
mg
20ml within 3 mins.

Erythromycin 250 mg Tablet Erythromycin suspension 200mg/5ml available

Escitalopram Lexapro® 10 mg, 20 mg Tablet Tablet can be crushed
Add 15 ml water to sachet and stir and leave for
Esomeprazole Nexium® 10 mg Sachet few mintues to thicken then stir again and draw
up dose
Ethambutol EMB-Fatol 100 mg, 400 mg Tablet Tablet can be crushed
Etoricoxib Arcoxia® 90 mg, 120 mg Tablet No information available on crushing
0.25 mg , Wear a mask and gloves. Crush the tablet and
Everolimus Certican® Tablet
0.5 mg mix with 30ml of water.
Wear a mask and gloves. Disperse tablet in 30 ml
Everolimus Afinitor® 5 mg, 10 mg Tablet of water, gently stir until the tablet is fully
disintegrated (~7min)
Exemestane Wear a mask and gloves. Disperse the tablet in
Exemestane 25 mg Film coated tablet
STADA water.
Ezetimibe Ezetrol® 10 mg Tablet Disperse tablet in water
Famciclovir Famvir® 250 mg Tablet Tablet can be crushed
Famotidine Pepcidine® 20 mg, 40 mg Film coated tablet Tablet can be dispersed in water or crushed.

Febuxostat Feburic® 80 mg Film coated tablet Crush the tablet and mix with water.
Felodipine extended 2.5 mg, 5 mg, Extended release
Plendil® Do not crush tablet
release 10 mg tablet
Crush the tablet and mix with water or a
Lipathyl Penta®
Fenofibrate 145 mg Film coated tablet spoonful of yoghurt/apple puree. The tablet does
145
not disperse easily and is hard to crush.
Ferrous sulpate 300 mg Tablet Disperse tablet in water
Ferrum Hausmann Vifor® 100 mg Chewable tablet Tablet can be crushed and oral drop available
Fexofenadine Telfast® 120 mg Tablet Disperse tablet in water
Fexofenadine/ Sustained release
Telfast D® Do not crush tablet
Pseudoephedrine tablet
Flavoxate Urispas® 200 mg Tablet Tablet can be crushed

Flecainide Tambocor® 100 mg Tablet Tablet can be crushed

PYNEH Pharmacy Department

 Common brand
Drug name Strength Dosage form Administration details
name

Fluconazole oral suspension 50 mg/5ml available.

® Oral capsule can also be opened and mixed with
Fluconazole Diflucan 50 mg Capsule
water

Fludrocortisone acetate Florinef® 100 mcg Tablet Disperse tablet in water

Fluoxetine Prozac® 10 mg, 20 mg Capsule Capsule can be opened and mixed with water

0.5 mg, 1 mg,

Flupenthixol Fluanxol® Tablet Disperse tablet in water
3 mg
Flupenthixol/
Deanxit® Tablet No information available on crushing
Melitracen
Flutamide Fluta-cell® 250 mg Tablet Do not crush tablet
Fluvoxamine Faverin® 50 mg, 100 mg Tablet Tablet can be crushed
Folic acid 5 mg Tablet Folic acid solution 2.5 mg/5 ml available
Folinic acid 15 mg Capsule Capsule can be opened
40 mg and
Frusemide Lasix® Tablet Frusemide oral solution 50 mg/5ml available
500 mg
Fusidic acid syrup 250 mg/5 ml available as
Fusidate sodium Fucidin® 250 mg Tablet alternative (250 mg sodium fusidate tablet =
357.1 mg fusidic acid syrup)
Neurontin® ,
Gabapentin 100 mg, 300 mg Capsule Capsule can be opened
Gabapentin Teva
Scored and can be halved. No information
Gabapentin Neurontin® 600 mg Film coated tablet
availabe on crushing
8 mg, 16 mg, Prolonged release Do not crush, break or chew. Not situtable for
Galantamine Reminyl®
24 mg capsule feeding via enteral feeding tubes

Disperse in half a glass of water, swirl occaionally

Gefitinib Iressa® 250 mg Film coated tablet
until the tablet is dispersed(~20mins)
Gemfibrozil Lopid® 300 mg Capsule No information on opening capsule available
Gemfibrozil Lopid® 600 mg Tablet Crush the tablet and mix with water.

Ginkgo Biloba extract Tanakan® 40 mg Tablet No information available on crushing

Gliclazide Diamicron® 80 mg Tablet Scored and tablet can be halved. Can be crushed

Modified release 60 mg tablet is scored and can be halved. Do not

Gliclazide MR Diamicron MR® 30 mg, 60 mg
tablet crush tablet
Scored and tablet can be halved. Can be
Glimepiride Amaryl® 2 mg, 4 mg Tablet
dispersed in water

Glipizide Minidiab® 5 mg Tablet Tablet can be crushed

Glyceryl trinitrate Angised® 500 mcg Sublingual tablet Tablet is administered sublingually
Tablet can be crushed and sprinkled on food if
needed. However, tablet is insoluble in water
Griseofulvin Fulcin® 125 mg Tablet
and inaccurate dosing might result if dose is
withdrawn by proportion
Haloperidol Haldol® 1 mg, 10 mg Tablet Haloperidol oral drops 2 mg/ml is available

PYNEH Pharmacy Department

 Common brand
Drug name Strength Dosage form Administration details
name

Hydralazine 10 mg, 25 mg Tablet Tablet can be crushed

Hydrocortisone 20 mg Tablet Tablet can be crushed
Hydroxychloroquine
Plaquenil® 200 mg Tablet Disperse tablet in water
sulphate
Cytotoxic agent. Wear a mask, gloves and
Hydroxyurea 500 mg Capsule glasses. Contents of the capsule can be emptied
into a glass of water and taken immediately.
Hydroxyzine Atarax® 10 mg, 25 mg Tablet Tablet can be crushed

Hydrochlorothiazide Apo-Hydro 25 mg Tablet Hydrochlorothiazide 2 mg/ml oral syrup available

Hyoscine Hyoscine butylbromide oral syrup 1 mg/ml
Holopon® 1 mg Tablet
methobromide available
Crushing tablet is not recommended. Ibuprofen
Ibuprofen Brufen® 200 mg Film coated tablet
oral suspension 100 mg/5ml available

Imatinib Imakrebin® 100 mg Film coated Tablet Tablet can be dissolved in water or apple juice

For patients who are unable to swallow, the

capsule contents may be dissolved in a glass of
Glivec®, Hemator
Imatinib 100 mg Capsule still water or apple juice (approximately 50 ml for
®
a 100 mg capsule). The solution should be
swallowed immediately
Imipramine HCL Tofranil® 25 mg Tablet Crush the tablet and mix with water
Indapamide Natrilix® 2.5 mg Tablet Tablet can be crushed
SR tablet is not suitable for crushing.
Indapamide Natrilix SR® 1.5 mg Slow release tablet
Recommend to change to regular release
Indomethacine Indocid® 25 mg Capsule Capsule can be opened
Practically insoluble in water. Crush tablet and
Irbesartan Aprovel® 150 mg, 300 mg Tablet
give with water or food

Irbesartan/ 150mg/12.5mg,
Co-Aprovel® 300mg/12.5 mg
Tablet No information available on crushing
Hydrochlorothiazide

Isoniazid 100 mg Tablet Isoniazid oral elixir 100 mg/5ml available

Isosorbide dinitrate Isordil® 10 mg Tablet Crushing of tablet not recommended
Isosorbide mononitrate Elantan® 20 mg Tablet Disperse tablet in water
Isosorbide mononitrate Controlled release
Imdur® 60 mg Scored and tablet can be halved. Do not crush
CR tablet
Capsule can be opened and content squeezed
Isotretinoin Roaccutane® 10 mg, 20 mg Capsule and mixed with 5-10 ml of warm water or milk.
Draw up the desired dosage by proportion
Itraconazole Sporanox® 100 mg Capsule Itraconazole oral solution 10 mg/ml is available
5 mg tablet is scored and can be halved. No
Ivabradine Coralan® 5 mg, 7.5 mg Film coated tablet
information available on crushing

PYNEH Pharmacy Department

 Common brand
Drug name Strength Dosage form Administration details
name

Labetalol Trandate® 100 mg, 200 mg Tablet Tablet can be crushed

Lacosamide Vimpat® 50 mg, 100 mg Film coated tablet Tablet can be dispersed in water or crushed.

Lamotrigine 5 mg and 25 mg chewable tablet

Lamotrigine Lamictal® 50 mg, 100 mg Tablet
available
Tablet will dissolve in mouth and follow with
Oral dispersible
Lansoprazole Takepron OD® 15 mg, 30 mg water or disperse tablet in 10-15 ml water and
tablet
draw up dose
Wear a mask and gloves. Disperse the tablet in
water. A dose of 1250mg requires a volume of
Lapatinib Tykerb® 250 mg Film coated tablet
120ml of water and takes up to 20mins to
disperse.
Leflunomide Arava® 10 mg, 20 mg Tablet Disperse tablet in water
10 mg, 15 mg, Capsule should not be opened or chewed.
Lenalidomide Revlimid® Capsule
Administer with or without a meal
25 mg
Can be dissolved in liquid; put capsules into 1
tablespoon of water or apple juice without
Lenvatinib Lenvima® 4 mg, 10 mg Capsule breaking or crushing the capsules; leave the
capsules in water or apple juice for at least 10
mins, stir for at least 3 mins
Wear a mask and gloves. Disperse the tablet in
Letrozole Femara® 2.5 mg Tablet
water, the tablet will disperse within 4mins
Levamisole 50 mg Tablet Tablet can be crushed
250 mg, Tablet can be crushed or sprinkled on food.
Levetiracetam Keppra® Tablet
500 mg, 1 gram Keppra oral solution 100 mg/ml available
Levocetirizine Xyzal® 5 mg Tablet No information available on crushing
Levodopa/ Tablets are breakable. Madopar dispersible
Madopar® 250 mg Tablet
benserazide tablet is available
Levodopa/ Madopar®
125 mg Tablet Can be dispersed in 25-50ml water
benserazide Dispersible
Levodopa/
Madopar HBS ® 125 mg Capsule Do not open capsule
benserazide
Levodopa/Carbidopa/ 100 mg/25 mg/200 Disperse tablet in water and can be mixed with
Stalevo ® mg
Tablet
Entacapone juice for administration
100 mg,
Levofloxacin Cravit® Film coated tablet Tablet can be crushed
250 mg
Linagliptin Trajenta® 5 mg Film coated tablet Crush the tablet and mix with water.
Linezolid Zyvox® 600 mg Tablet Linezolid 100 mg/5ml oral suspension available
5 mg, 10 mg,
Lisinopril Zestril® Tablet Disperse tablet in water
20 mg
Scored and tablet can be halved. No information
Lithium carbonate Camcolit® 250 mg Tablet
on crushing available
Controlled release
Lithium carbonate CR Priadel® 400 mg Scored and tablet can be halved. Do not crush
tablet
Lomustine 10 mg, 40 mg Capsule Cytotoxic agent. Do not open capsule.
Loperamide Imodium® 2 mg Capsule Capsule can be opened and dispersed in water

Lopinavir/ritonavir Kaletra® 200 mg/50 mg Film coated tablet Oral solution 80mg/20mg/ml available

PYNEH Pharmacy Department

 Common brand
Drug name Strength Dosage form Administration details
name

Loratadine Clarityne® 10 mg Tablet Loratadine 5 mg/5ml oral syrup available

Loratadine/ Clarinase
Tablet Do not crush tablet
pseudoephedrine Repetabs®
Loratadine/ Clarinase Extended release
Do not crush tablet
pseudoephedrine Extended Release tablet
Losartan Cozaar® 50 mg, 100 mg Tablet Tablet can be crushed

Losartan/ 50 mg/12.5 mg,

Hyzaar® Tablet No information available on crushing
Hydrochlorothiazide 100 mg/12.5 mg

Lysozyme Neuzym® 30 mg Tablet Tablet can be crushed

Magnesium (L-lactate
Mag tab SR® 84 mg Slow release tablet Do not crush tablet
dihydrate) SR

Mebendazole Vermox® 100 mg Tablet Tablet can be crushed

Duspatalin® Prolonged release

Mebeverine 200 mg Do not open prolonged release capsule
retard capsule
Mecobalamine Norcobal® 500 mcg Tablet No information available on crushing
® Tablet can be crushed
Medroxyprogesterone Provera 5 mg Tablet
Mefenamic acid Ponstan® 250 mg Capsule No information on opening capsule available
Wear a mask and gloves. Tablets disintegrate
Megestrol acetate Megace® 40 mg Tablet rapidly when placed in 10 mL of water to give a
fine dispersion
Melphalan Alkeran® 2 mg Tablet Cytotoxic agent. Do not crush tablet
Scored and tablet can be halved. No information
Memantine Ebixa® 10 mg Tablet
on crushing available
Mercaptopurine 50 mg Tablet Cytotoxic agent. Do not crush tablet
Mesalazine Salofalk® 250 mg Enteric coated tablet Do not crush tablet
Prolonged release Mesalazine prolonged release 1 gm/sachet
Mesalazine Pentasa® 1 gram
tablet granule available
250 mg, 500
Metformin HCL Glucophage® Tablet Tablet can be crushed
mg
500 mg, Prolonged release
Metformin HCL Glucophage XL® Do not crush tablet
1000mg tablet
Methimazole 5 mg Tablet No information available on crushing
Cytotoxic agent. Wear a mask and gloves.
Methotrexate 2.5 mg Tablet Disperse the tablet in 10-20ml of water in an oral
dispenser/enteral syringe.
125 mg, 250
Methyldopa Aldomet® Tablet Tablet can be crushed
mg
Metoclopramide HCL Maxolon® 10 mg Tablet Metoclopramide 5 mg/5ml oral syrup available

Metolazone Diulo® 5 mg Tablet Disperse tablet in water

Metoprolol Betaloc® 50 mg, 100 mg Tablet Tablet can be crushed

25 mg, 50 mg, Controlled release Scored and tablet can be halved. Do not crush
Metoprolol CR Betaloc Zok®
100 mg tablet controlled release tablet
Metronidazole Flagyl® 200 mg Tablet Metronidazole oral syrup 200 mg/5 ml available

PYNEH Pharmacy Department

 Common brand
Drug name Strength Dosage form Administration details
name

Disperse the tablet in water. The tablet will

Mianserin HCL Tolvon® 10 mg, 30 mg Tablet
disperse in 2 to 5 mins.
Milnacipran Ixel® 25 mg, 50 mg Capsule Swallow whole capsule
Open the capsule and disperse the contents in
water. If the person cannot swallow thin fluids,
Minocycline Minocin® 100 mg Capsule
mix the contents of capsule with a spoonful of
yoghurt or apple puree.
Oral dispersible Soltabs melt on the tongue. They also disperse in
Mirtazapine Remirta OD ® 15 mg, 30 mg
water
tablet
Misoprostol Cytotec® 200 mcg Tablet Do not crush due to poor stability
Moclobemide Aurorix® 150 mg Tablet Disperse tablet in water
4 mg and 5 mg chewable tablet and 4 mg sachet
Montelukast Singulair® 10 mg Tablet
available
Moxifloxacin Avelox® 400 mg Tablet Tablet can be crushed
Cellcept®, Do not open capsule due to teratogenicity of the
Mycophenolate mofetil 250 mg Capsule
Micocept® drug
Cellcept®, Do not crush tablet due to teratogenicity of the
Mycophenolate mofetil 500 mg Tablet
Micocept® drug
180 mg, 360 Do not crush tablet due to teratogenicity of the
Mycophenolate sodium Myfortic® Enteric coated tablet
mg drug
Do not open capsule as will cause irritation to
Naftidrofuryl oxalate Praxilene® 100 mg Capsule esophagus. However, content can be given via
enteral feeding tube
Naftidrofuryl oxalate Praxilene® 200 mg Tablet Do not crush tablet
Naproxen 250 mg Tablet Tablet can be crushed
Neomycin Neoate® 250 mg Tablet Disperse tablet in water
Netupitant / PalonosetronAkynzeo® 300mg/0.5mg Capsule The hard capsule should be swallowed whole
Neurobion® Tablet Do not crush tablet
Nicergoline Sermion® 10 mg, 30 mg Tablet No information available on crushing
Extended release
Nicotinic acid 500 mg Do not crush tablet
tablet
Internal volumes vary between manufacturer,
Nifedipine Adalat® 5 mg Capsule accurate dosing could be problematic when
dosage is being drawn
Nifedipine (extended Extended release film
Adalat GITS® 30 mg Do not crush tablet
release tablet) coated tablet

For patients who are unable to swallow, the

content of each capsule maybe dispersed in one
teaspoon of apple sauce and should be taken
150 mg, 200
Nilotinib Tasigna® Capsule immediately. Not more than one teaspoon of
mg
apple sauce and no food other than apple sauce
must be used. Administer at least 1 hour before
or 2 hours after a meal

Nimodipine Nimotop® 30 mg Film coated tablet Disperse tablet in water

PYNEH Pharmacy Department

 Common brand
Drug name Strength Dosage form Administration details
name

Tablet can be crushed. Nitrofurantoin 10mg/ml

Nitrofurantoin 50 mg Tablet
oral suspension is available
Norethisterone Primolut N® 5 mg Tablet Disperse tablet in water
Disperse the tablet in water. The tablet will
Nortriptyline 10 mg, 25 mg Tablet
disperse in 2 mins.
0.3 mg,
Oestrogens conjugated Premarin® Tablet No information available on crushing
0.625 mg
Ofloxacin Tarivid® 100 mg Tablet Tablet can be crushed
Oral dispersible tablet. It may also be dispersed
Oral dispersible in full glass of water or other suitable beverage
Olanzapine Onzapin OD® 5 mg , 10 mg
( orange juice, apple juice, milk or coffee )
tablet
immediately before administration
Omeprazole mups Losec Mups® 10 mg Tablet Disperse tablet in water

Disperse the tablet in 10-20ml of water. The

Ondansetron Zofran® 4 mg, 8 mg Tablet
tablet will disperse within 5 mins.
30 mg, 45 mg, Capsule can be opened and content can be
Oseltamivir Tamiflu® Capsule
75 mg mixed with sweetened liquid
Do not crush, split or chew; disperse in 50ml of
water, stir until dispersed and immediately
swallowed; then rinse with
Osimertinib Tagrisso® 80mg film coated tablet same volume of water and swallow
Nasogastic tube:
Same as above but using volumes of 15mL for
initial dispersion and 15mL for residue rinses
Tablet is scored and can be halved.
300 mg, 600
Oxcarbazepine Trileptal® Tablet Oxcarbazepine 300 mg/5ml oral suspension also
mg
available
Oxpentifylline Controlled release
Trental® 400 mg Do not crush tablet
(pentoxifylline) CR tablet
Oxybutynin HCL Ditropan® 5 mg Tablet Tablet can be crushed
Paliperidone extended 3 mg, 6 mg, Extended release
Invega® Do not crush tablet
release 9 mg tablet
Capsule can be opened but granules must not be
Pancreatin Creon® 150 mg Capsule
crushed
Pantoprazole Pantoloc® 20 mg, 40 mg Tablet Do not crush tablet
Paracetamol 125 mg/5 ml oral suspension
Paracetamol Panadol® 500 mg Tablet
available
Scored tablet and can be halved. Crush the tablet
Paroxetine 20 mg Tablet and mix with water. The tablet does not disperse
but is easily crushed.
12.5 mg, 25 Controlled release
Paroxetine CR Seroxat CR® Do not crush tablet
mg tablet
Tablet should not be broken or crushed. Please
note crushing significantly increases AUC and
Pazopanib Votrient® 200 mg Film coated tablet
Cmax. Administer at least 1 hour before or 2 hours
after a meal
Penicillamine 250 mg Tablet Dipserse tablet in water

PYNEH Pharmacy Department

 Common brand
Drug name Strength Dosage form Administration details
name

Scored tablet and can be halved. Wear gloves.

Pericyazine Neulactil® 2.5 mg, 10 mg Tablet Disperse the tablet in water. The tablet will
disperse within 1 min.
Perindopril Acertil® 2 mg, 4 mg Tablet Dipserse tablet in water
2 mg, 4 mg,
Perphenazine Enteric coated tablet Do not crush tablet
8 mg
Phenazopyridine Pyridium® 100 mg Tablet Tablet can be crushed

Phenobarbitone Luminal ® 30 mg, 60 mg Tablet Phenobarbitone oral syrup 15 mg/5 ml available

Wear a mask and gloves. Open the capsule and

Phenoxybenzamine 10 mg Capsule
disperse the contents in water.
Phenoxymethyl- Phenoxymethylpenicillin potassium 125 mg/5 ml
Pen V® 250 mg Tablet
oral suspension available
penicillin potassium
Capsule, extended
Phenytoin sodium Dilantin® 30 mg, 100 mg Phenytoin oral suspension 125 mg/5 ml available
oral capsule
K1 injection solution 2mg/0.2 ml can be used
Phytomenadion ( K1) 5 mg Tablet
orally
Pimozide Orap® 1 mg, 4 mg Tablet Disperse tablet in water
Pioglitazone Actos® 15 mg, 30 mg Tablet Tablet can be crushed
Pioglitazone+metformin Actosmet® 15mg/850mg Tablet Tablet can be crushed
Scored tablet and can be halved. No information
Piracetam Nootropil® 800 mg Tablet
available on crushing
Opening or crushing of capsule is not
Piroxicam Feldene® 10 mg Capsule
recommended
Pizotifen Sandomigran® 0.5 mg Film coated tablet Crush the tablet and mix with water.
Do not crush tablet. Potassium chloride 1 gm/10
Potassium chloride Slow-K® 600 mg Slow release tablet
ml oral solution available
Extended release
Potassium citrate Urocit-K® 10 meq Do not crush tablet
tablet
Pramipexole 0.375 mg,
Extended release
dihydrochloride Mirapex ER® 0.75 mg and Do not crush, divide or chew tablet
tablet
extended release 1.5 mg
Prasugrel Effient® 5 mg, 10 mg Tablet Tablet can be crushed

Tablet can be divided in half or quarter. Do not

Praziquantel 600 mg Tablet
chew tablet due to bad taste

1 mg, 2 mg,
Prazosin Minipress® Tablet Disperse tablet in water
5 mg
1 mg, 5 mg,
Prednisolone Tablet Prednisolone oral liquid 5 mg/ml available
25 mg
25 mg, 75 mg,
Pregabalin Lyrica® Capsule Capsule can be opened and dissolved in water
150 mg
Disperse the tablet in water. The tablet will
Probenecid 500 mg Tablet
disperse in 2 to 5 mins.
Cytotoxic agent. Do not open or crush the
Procarbazine 50 mg Capsule
capsule.
Prochlorperazine Stemetil® 5 mg Tablet Tablet can be crushed
Promethazine HCL Phenergan® 10 mg, 25 mg Tablet Promethazine oral elixir 5 mg/5ml available

PYNEH Pharmacy Department

 Common brand
Drug name Strength Dosage form Administration details
name

Promethazine Theoclate Avomine® 25 mg Tablet No information available on crushing

Propafenone 150 mg Tablet Tablet can be crushed

Propantheline 15 mg Tablet Crush the tablet and mix with water.
Propranolol Inderal® 10 mg, 40 mg Tablet Disperse tablet in water

Propyl thiouracil 50 mg Tablet Dipserse tablet in water

Pyrazinamide 500 mg Tablet Pyrazinamide oral syrup 1 gm/10 ml available

Pyridostigmine Mestinon® 10 mg, 60 mg Tablet Disperse tablet in water

Pyridoxine (Vitamin B6) 10 mg, 50 mg Tablet Disperse tablet in water

Quetiapine Seroquel® 25 mg, 100 mg Tablet Disperse tablet in water

50 mg, 200 Extended release

Quetiapine XR Seroquel XR® Do not crush tablet
mg, 300 mg tablet
Regorafenib Stivarga® 40 mg film coated tablet Do not crush or break the tablet.

Dissolve 200 mg tablet in 10ml of water in an oral

Ribavirin Copegus® 200 mg Film coated tablet
syringe with gentle shaking

Teratogenic. Capsules should not be opened,

Ribavirin Robatrol® 200 mg Capsule crushed, or broken . Use tablet form for patient
on NG tube or with swallowing difficulties

Rabeprazole Pariet® 10 mg, 20 mg Enteric coated tablet Do not crush tablet

Ramipril Tritace® 2.5 mg, 5 mg Tablet Tablet can be crushed

Ranitidine Zantac® 150 mg Tablet Ranitidine oral syrup 150 mg/10 ml available

Riboflavine (Vitamin B2) 20 mg Tablet Tablet can be crushed

150 mg, 300

Rifampicin Capsule Rifampicin oral syrup 100 mg/5 ml available
mg
Risedronate Actonel® 35 mg Tablet Do not crush tablet
1 mg, 2 mg , Risperidone orodispersible tablet 1 mg and 2 mg
Risperidone Risperdal® Tablet
3 mg, 4 mg available
Oral dispersible Tablet will dissolve in mouth and follow with
Risperidone Risperdal Quicklet® 1 mg, 2mg
tablet water
1.5 mg, 3 mg,
Rivastigmine Exelon® Capsule Consider switching to transdermal patch
4.5 mg, 6 mg
The tablet maybe crushed or mixed with water or
Rivaroxaban Xarelto® 15 mg, 20 mg Tablet
apple puree immediately before taking
Tablet should be swallowed whole as
Roflumilast Daxas® 500 mcg Tablet
recommended by manufacturer
2 mg, 4 mg, Prolonged release
Ropinirole Requip® Swallow whole and do not chew, crush or divide
8 mg tablet
Rosuvastatin Crestor® 10 mg, 20 mg Tablet Disperse tablet in water

Salbutamol Ventolin® 4 mg Tablet Salbutamol oral syrup 2 mg/ml available

PYNEH Pharmacy Department

 Common brand
Drug name Strength Dosage form Administration details
name

Crush and mix with water. Onglyza tablet does

Saxagliptin Onglyza® 5 mg Tablet
not disperse easily and is very hard to crush.
Selegiline 5 mg Tablet Tablet can be divided and dispersed in water
Senna Senokot® 7.5 mg Tablet Tablet can be crushed
Sertraline Zoloft® 50 mg Tablet Tablet can be crushed

Sevelamer Renagel® 800 mg Tablet Do not crush tablet

Sildenafil Revatio® 20 mg Tablet Tablet can be crushed

10 mg, 20 mg,
Simvastatin Zocor® Tablet Crush the tablet and mix with water.
40 mg
Sirolimus Rapamune® 1 mg Tablet Do not crush tablet
Disperse Januvia tablet in water. Januvia will
Sitagliptin Januvia® 50mg, 100 mg Tablet
disperse within 3 mins.
50 mg/500 mg, Crush the tablet and mix with water. Janumet is
Sitagliptin/Metformin Janumet® Tablet
50 mg/1000 very hard to crush.
Sodium bicarbonate 300 mg Tablet Tablet can be crushed

Sodium chloride 900 mg Tablet Tablet can be crushed

Solifenacin Vesicare® 5 mg, 10 mg Tablet Disperse tablet in water

Wear a mask and gloves. Disperse 1 or 2 tablets

® in 60ml of water. Let stand for 5mins, then shake
Sorafenib Nexavar 200 mg Film coated tablet
until completely dispersed.

Sotalol 80 mg Tablet Tablet can be crushed

Spironolactone Aldactone® 25 mg Tablet Spironolactone oral syrup 4 mg/ml available
Sucrafate 1 gm/sachet oral gel suspension
Sucralfate 1 gm Tablet
available
Sulindac 200 mg Tablet Tablet can be crushed
Sulpiride Dogmatil® 50 mg Capsule No information on opening capsule available
Sulpiride Dogmatil® 200 mg Tablet Disperse tablet in water
Salazopyrin Entab
Sulphasalazine 500 mg Enteric coated tablet Do not crush tablet
®
Sumatriptan Imigran® 50 mg Tablet Do not crush tablet
Empty content of capsule and mix each capsule
with 5ml of NS, rinse twice with NS after
Sunitinib Sutent® 12.5 mg Capsule
administration. Administer with or without a
meal
Cytotoxic agent. No information available on
TAS-102 Lonsurf® 15 mg, 20 mg film coated tablet
crushing
0.5 mg, 1 mg, Capsule can be opened and dispersed as a
Tacrolimus Prograf® Capsule
suspension
5 mg
Wear a mask and gloves. Disperse the tablet in
Tamoxifen 20 mg Tablet
water, the tablet will disperse in 2 to 5 mins.
Prolonged release
Tamsulosin Harnal OCAS® 0.4 mg Do not open, chew, crush capsule
tablet
Telmisartan Micardis® 40 mg, 80 mg Tablet Tablet can be crushed

PYNEH Pharmacy Department

 Common brand
Drug name Strength Dosage form Administration details
name

Hygroscopic. Open blister foil immediately before

Telmisartan/ administration. Do not save opened tablet for
Mircardis® Plus 40 mg/12.5 mg Tablet
Hydrochlorothiazide next dose. Crushing or splitting tablet is not
recommended by manufacturer
Cytotoxic agent. Wear a mask and gloves. Open
Temozolomide Temodar® 20 mg, 100 mg Capsule the capsule and mix the contents with apple juice
or apple puree.

1 mg, 2 mg, 1 mg and 2 mg tablet are both scored and can be

Terazosin Hytrin® Tablet
5 mg halved

Do not crush tablet. Terbutaline sulphate syrup

Terbutaline Bricanyl SR® 5 mg, 7.5 mg Slow release tablet
0.3 mg/ml available
Terbinafine Lamisil® 250 mg Tablet Tablet can be crushed
Testosterone
Andriol® 40 mg Capsule Do not open the capsule.
undeconoate
Tetrabenazine 25 mg Tablet Tablet can be crushed
Tetracycline 250 mg Capsule No information on opening capsule available
Thalidomide 50 mg Tablet No information on crushing tablet available
Capsule can be opened but do not crush pallets.
Theophylline Slo-Theo® 100 mg Slow release capsule
Theophylline syrup 80mg/15ml available
200 mg, 300 Scored tablet and can be halved. Do not crush.
Theophylline Neulin SR® Slow release tablet
mg Theophylline syrup 80mg/15ml available
Thiamine
10 mg, 50 mg Tablet Tablet can be crushed
(Vitamin B1)
10 mg, 25 mg,
Thioridazine Melleril® Tablet No information available on crushing
50 mg, 100 mg
Thiothixene 10 mg Capsule No information on opening capsule available
50 mcg,
Thyroxine Tablet Tablet can be crushed
100 mcg
Tolterodine Detrusitol® 2 mg Tablet Tablet can be crushed
Crushing is not recommended. Disperse tablet
25 mg, 50 mg,
Topiramate Topamax® Film coated tablet immediately in water prior to administration if
100 mg
alternative therapy is not feasible
Tramadol 50 mg Capsule Capsule can be opened

Tranexamic acid Transamin® 250 mg Capsule Capsule can be opened and dispersed in water

Trazodone 50 mg Tablet No information available on crushing tablet

Triamterene/ Scored and tablet can be halved. Tablet can be
Dyazide® 50 mg/25 mg Tablet
Hydrochlorothiazide crushed
Trifluoperazine Stelazine® 1 mg, 5 mg Tablet Crush the tablet and mix with water.
Trimipramine Surmontil® 25 mg Tablet Tablet can be crushed
Modified release
Trimetazidine Vastarel MR® 35 mg Do not crush tablet
tablet
Cytotoxic agent. No information available on
TS-1 TS-ONE® 20 mg Capsule
crushing
Ubidecarenone Eiquinon® 10 mg Tablet No information available on crushing

PYNEH Pharmacy Department

 Common brand
Drug name Strength Dosage form Administration details
name

Ursodeoxycholic acid Ursofalk® 250 mg Capsule Capsule can be opened and sprinkled on food

Valaciclovir Valtrex® 500 mg Tablet Tablet can be crushed

Valganciclovir Valcyte® 450 mg Tablet Do not crush tablet
Do not crush tablet. Oral solution 200 mg/5 ml
Valproate Sodium Epilim EC® 200 mg Enteric coated tablet
available
200 mg, Do not crush tablet . Hygroscopic, do not open
Controlled release
Valproate Sodium Epilim® Chrono 300 mg, 500 blister until ready to administer. Oral solution
tablet
mg 200 mg/5 ml available
Valproate Sodium Epilim Crushable 100 mg Tablet Uncoated tablet and can be crushed
Valsartan Diovan® 80 mg Tablet Disperse tablet in water
Valsartan/
Co-Diovan® 80 mg/12.5 mg Tablet No information available on crushing
Hydrochlorothiazide
37.5 mg, 75 Extended release Capsule can be opened but do not crush or chew
Venlafaxine Efexor XR®
mg, 150 mg capsule on pallets
Verapamil Isoptin® 40 mg Tablet Tablet can be crushed
Scored tablet and can be halved. Disperse tablet
Vigabatrin Sabril® 500 mg Tablet
in water
Vildagliptin Galvus® 50 mg Tablet Crush the tablet and mix with water.

Voriconazole Vfend® 50 mg, 200 mg Tablet Tablet can be crushed

Warfarin 1 mg, 3 mg Tablet Tablet can be crushed

50 mg
Zinc sulphate (elemental) Capsule Capsule can be opened and dissolved in water
zinc
20 mg, 40 mg, Wear gloves. Open the capsule and disperse the
Ziprasidone Zeldox® Capsule
60 mg, 80 mg contents in water.
Scored tablet and can be halved. Disperse the
Zolmitriptan Zomig® 2.5 mg Tablet
tablet in water. The tablet will disperse in 3-5
Scored tablet and can be halved. Tablet can be
Zolpidem Stilnox® 10 mg Tablet
dispersed in water or crush.
Crushed tablet has bitter taste. Tablets dissolve
Zopiclone Imovane® 7.5 mg Tablet
in acidic fruit juice ( orange ) or disperse in water
Zuclopenthixol Clopixol 25 mg Film coated tablet Disperse tablet in water
Last updated: Jun, 2021
References:
1. MIMS
2. Micromedex
3. White R, Bradnam V. Handbook of Drug Administration via Enteral Feeding Tubes. 3rd edition. Royal Pharmaceutical Society of Great Brintain. 2015
4. Clifton M. NEEMMC guidelines for tablet crushing and administration via enteral feeding tubes. Colchester Medicines Information.
Colchester Hospital University. NHS foundation trust. 2012
5. Product inserts
6. www.webmd.com
7. eMC product information
8. Lexicomp
9. Enteral tube administration of oral chemotherapy drugs. Journal of Oncology Pharmacy Practice 2020. Vol 26(3), 703-717
10. Australian Don't Rush to Crush Handbook. Third edtion. SHPA

PYNEH Pharmacy Department

 Common brand
Drug name Strength Dosage form Administration details
name

Disclaimer:Please note the above information provided is intended for informational purposes only and it is necessary to contact a pharmacist when in doubt.
Administration of drugs via enteral feeding tubes will generally be outside of the marketing authorization as manufacturers do not intend to test or license drugs for
this route. It is possible that the bioavailability of the drug might be significantly altered after being crushed. Furthermore, there is limited evidence demonstrating
that drug is lost on the tube itself and this again will affect the effectivness of the drug.3 Content of tablet/capsule crushed or opened should be consumed
immediately as the stability of the involved drug cannot be guaranteed.

PYNEH Pharmacy Department