Cell Cycle and Chromosomes Question Paper (1)
Cell Cycle and Chromosomes Question Paper (1)
Marks: 100
1. Interphase is considered a resting phase, yet intense metabolic activity occurs. Justify this
contradiction.
2. A mutation affects the centromere of a chromosome. Predict and explain the likely effect
on mitosis.
3. Why is it incorrect to say that all cells undergoing interphase are “dividing”?
4. If a somatic cell skips the S phase but continues to mitosis, what anomaly may arise?
5. Differentiate between chromatin and chromatid based on structural state and functional
implications.
6. How does mitotic division ensure genetic continuity, despite biochemical variability
between cells?
7. Predict the result if cytokinesis fails after mitosis. How would this impact the cell's future
division capability?
8. Why is meiosis referred to as a ‘reduction division’, and how does this impact variation?
9. A drug inhibits spindle fiber formation during cell division. At which mitotic stage will the
process halt? Explain.
10. The number of chromosomes remains the same in mitosis but halves in meiosis. Explain
this functional necessity in organisms.
Section B – Short Answer Type Questions (3 marks each)
(6 × 3 = 18 marks)
Requires logical explanations, drawing connections between concepts.
11. A nerve cell remains in interphase for a lifetime. Explain this in context of G1, S, and G2
phases.
12. Why is mitosis unsuitable for producing gametes? Include chromosome behavior in your
answer.
13. A scientist isolates a cell and finds it contains twice the normal amount of DNA. Identify
the cell cycle stage and justify your reasoning.
14. If an error occurs in the anaphase of mitosis and one daughter cell receives both
chromatids of a chromosome, predict the outcome for that cell lineage.
16. “DNA replication ensures genetic continuity, but recombination ensures genetic
diversity.” Analyse this statement with examples from meiosis and mitosis.
17. A student observes under a microscope a cell with condensed chromosomes aligned at
the equator, spindle fibers attached, and no visible nuclear envelope.
18. During a genetic experiment, scientists observed that an organism’s gametes had a
random mix of maternal and paternal chromosomes.
a) Identify the phases of the cell cycle corresponding to 0–30, 30–60, 60–90 min.
d) If DNA doubled at 30 mins but didn’t halve at 90, what anomaly might that suggest?
20. A mutation occurs in the gene coding for a spindle fiber protein, causing it to
malfunction.
a) Predict the mitotic phase where this will have maximum impact.
22. A researcher is examining a cell with visible centromeres, each holding two sister
chromatids, and chromosomes beginning to move apart.
b) How does the centromere's role change before and after this stage?
a) Behavior of chromosomes.
b) Genetic outcome.
c) Functional significance.
24. Consider a scenario where a multicellular organism begins to produce gametes via
mitosis instead of meiosis.
26. Describe how checkpoints in the cell cycle prevent abnormalities. Include:
c) Structural differences.
28. Imagine two cells: one undergoes mitosis and the other meiosis. Both start with 8
chromosomes.
d) Justify why one cell contributes to body growth and the other to genetic lineage.