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Lab Result

The lab report for Mr. Awdhesh Kumar indicates the isolation of Klebsiella pneumoniae from an E.T. aspirate sample, with a significant growth of over 1 lakh CFU/ml. The organism shows resistance to multiple antibiotics, including Ampicillin and various cephalosporins, while displaying synergy between Ceftazidime avibactam and Aztreonam. The report emphasizes the limited clinical efficacy of colistin and recommends alternative treatments if available.

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0% found this document useful (0 votes)
2 views3 pages

Lab Result

The lab report for Mr. Awdhesh Kumar indicates the isolation of Klebsiella pneumoniae from an E.T. aspirate sample, with a significant growth of over 1 lakh CFU/ml. The organism shows resistance to multiple antibiotics, including Ampicillin and various cephalosporins, while displaying synergy between Ceftazidime avibactam and Aztreonam. The report emphasizes the limited clinical efficacy of colistin and recommends alternative treatments if available.

Uploaded by

nobukowa56
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We take content rights seriously. If you suspect this is your content, claim it here.
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DEPARTMENT OF LAB.

SCIENCES
Patient Name Mr. Awdhesh Kumar Lab No 133848 OPD
UHID/IP No 6167965 Sample Date 15/02/2025 5:58PM
Age/Gender 54 Yrs/Male Receiving Date 15/02/2025 5:58PM
Company CASH Report Date 18/02/2025 3:30PM
Mob. No. 7754881442 Report Status. Final
Referred By .VISHAL KHANNA

MICROBIOLOGY

Nature of Specimen E.T. ASPIRATE


Organism Isolated Klebsiella pneumoniae
Growth/Colony Count >1 Lakh CFU/ml
Comment Synergy seen between
Ceftazidime avibactum &
Aztreonam
Antibiotic Name Interpretation MIC(ug/ml)
Ampicillin IR NA
Ampicillin-sulbactam R *(NA)
Amoxycillin/Clavulanate R >=32
Piperacillin-tazobactam R >=128
Cefazolin R *(NA)
Cefuroxime R >=64
Ceftazidime Avibactam R *(NA)
Cefotaxime R #(NA)
Ceftriaxone R >=64
cefoperazone sulbactam R >=64
Cefexime R *(NA)
Cefepime R >=32
Cefepime-tazobactam R *(NA)
Aztreonam R *(NA)
Imipenem R >=16
Meropenem R >=16
Ertapenem R >=8
Ciprofloxacin R >=4
Tetracycline R *(NA)
Doxycycline R *(NA)
Tigecycline R 1
Minocycline R *(NA)
Gentamicin R >=16
Amikacin R 32
Tobramycin R *(NA)
Colistin Intermediate <=0.5
Co-trimoxazole R >=320

Dr. NITI LUTHRA MD Dr. CHAND NIGAM MD


MICROBIOLOGIST MICROBIOLOGIST

Printed on 21/02/2025 18:33 Page: 1 Of 3


DEPARTMENT OF LAB. SCIENCES
Patient Name Mr. Awdhesh Kumar Lab No 133848 OPD
UHID/IP No 6167965 Sample Date 15/02/2025 5:58PM
Age/Gender 54 Yrs/Male Receiving Date 15/02/2025 5:58PM
Company CASH Report Date 18/02/2025 3:30PM
Mob. No. 7754881442 Report Status. Final
Referred By .VISHAL KHANNA

Note
(* NA)- MIC not applicable because these drug were tested by disk diffusion method (Kirby-
Bauer technique)
(#NA)- MIC not applicable because this was deduced result.
IR(NA) The organisms is intrinsically resistance to these drugs.
R- Resistant
NOTE:

WARNING NOTE FOR COLISTIN

a) Susceptible breakpoint of <=2 µg/ml is not provided since this would include the wild type distribution of
Enterobacterales. Rationale for an intermediate-only breakpoint suggests a black box warning that the seagents are of
limited 2 clinical efficacy even for isolates with MIC values<2µg/ml.

b) Clinical and PK/PD data demonstrate this agent is of limited clinical efficacy.

c) If available, alternative [non-polymyxin] agents are strongly preferred. If the seagents are not available, this breakpoint
presumes use of colistin in combination with 1 or more additional, active antimicrobials.

d) Colistin (methanesulfonate) and Polymyxin B should be given with a loading dose and maximum renal adjusted doses.

e) When given systemically, this drug is unlikely to be effective for pneumonia

Klebsiella pneumoniae is intrinsically resistant to Ampicillin and Ticarcillin.

Clinical Interpretation Of MIC


MIC Of Enterobacteriaceae

Antimicrobial Agent Break Point MIC (ug/ml)

Ampicillin : <=8
Ampicillin -sulbactam : <22
Amoxycillin/Clavulanic acid : <=8
Piperacillin/Tazobactam : <=8
Cefazolin (Other than UTI) : <=2
Cefazolin (For UTI) : <=16
Cefuroxime : 4
Cefotaxime : <1
Ceftriaxone : <=1
Cefoperazone-Sulbactam(FDA) : <=8

Dr. NITI LUTHRA MD Dr. CHAND NIGAM MD


MICROBIOLOGIST MICROBIOLOGIST

Printed on 21/02/2025 18:33 Page: 2 Of 3


DEPARTMENT OF LAB. SCIENCES
Patient Name Mr. Awdhesh Kumar Lab No 133848 OPD
UHID/IP No 6167965 Sample Date 15/02/2025 5:58PM
Age/Gender 54 Yrs/Male Receiving Date 15/02/2025 5:58PM
Company CASH Report Date 18/02/2025 3:30PM
Mob. No. 7754881442 Report Status. Final
Referred By .VISHAL KHANNA
Cefexime : <=1
Cefepime : <=2
Aztreonam : <=4
Imipenem : <=1
Meropenem : <=1
Ertapenem : <=0.5
Nitrofurantoin : <=32
Norfloxacin : <=4
Ciprofloxacin : <=0.25
Ciprofloxacin (For Sal. spp.) : <=0.06
Ofloxacin : <=2
Levofloxacin : <=0.5
Azithromycin (Only S. Typhi) : <=16
Azithromycin (Shigella) : <=8
Tetracycline : <=4
Doxycycline : <=4
Tigecycline : <=0.5
Gentamicin : <=4
Amikacin : <=16
Tobramycin : <4
Chloramphenicol : <=8
Cotrimoxazole : <=40
Fosfomycin : <=64

Break Point MIC


Break Point Quotient = ------------------------
Actual MIC (of patient)

Higher Break Point Quotient higher the Probability of Clinical Success.


Note

1. Bacterial pathogens in concentrations of more than 1000 cfu per mL in cultures of


PTC, more than 10,000 cfu per mL in cultures of BAL specimens and more than
1 lac. cfu/mL in cultures of EA/TA are considered to be causative agents of lower
respiratory tract infections.
2. The growth of microorganisms that are ordinarily not pathogenic, such as Streptococcus
viridans and Staphylococcus epidermidis, are considered to be colonizers.
3. Isolations of Candida spp. considered significant when associated with positive blood
cultures, or when histological evidence of pneumonia caused by Candida is present or
it correlates with clinical picture.

--End Of Report--

Dr. NITI LUTHRA MD Dr. CHAND NIGAM MD


MICROBIOLOGIST MICROBIOLOGIST

Printed on 21/02/2025 18:33 Page: 3 Of 3

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