NORMAL LABORATORY VALUES

MKSAP 14
U.S. traditional units are followed in parentheses by equivalent values expressed in S.I. units.

Hematology
Activated partial thromboplastin time 25-35 s Bleeding time Less than 10 min Erythrocyte count 4.2-5.9 106/L (4.2-5.9 x 1012 cells/L) Erythrocyte sedimentation rate Male: 0-15 mm/h Female: 0-20 mm/h Erythropoietin less than 30 mU/mL (30 U/L) D-Dimer less than 0.5 g/mL (500 mg/L) Ferritin, serum 15-200 ng/mL (15-200 mg/L) Haptoglobin, serum 50-150 mg/dL (500-1500 mg/L) Hematocrit Male: 41%-51% Female: 36%-47% Hemoglobin, blood Male: 14-17 g/dL (140-170 g/L) Female: 12-16 g/dL (120-160 g/L) Leukocyte alkaline phosphatase 15-40 mg of phosphorus liberated/h per 1010 cells; score = 13-130/100 polymorphonuclear neutrophils and band forms Leukocyte count 4000-10,000/L (4.0-10 109/L) Mean corpuscular hemoglobin 28-32 pg Mean corpuscular hemoglobin concentration 32-36 g/dL (320-360 g/L) Mean corpuscular volume 80-100 fL Platelet count 150,000-350,000/L (150-350 109/L) Prothrombin time 11-13 s Reticulocyte count 0.5%-1.5% of erythrocytes; absolute: 23,00090,000 cells/L (23-90 109/L) Schilling test (oral administration of radioactive cobalamin-labeled vitamin B12) 8.5%-28% excreted in urine per 24-48 h

Blood, Plasma, and Serum Chemistry Studies

Albumin, serum 3.5-5.5 g/dL (35-55 g/L) Alkaline phosphatase, serum 36-92 U/L -Fetoprotein, serum 0-20 ng/mL (0-20 g/L) Aminotransferase, alanine (ALT) 0-35 U/L Aminotransferase, aspartate (AST) 0-35 U/L Ammonia, plasma 40-80 g/dL (23-47 mol/L) Amylase, serum 0-130 U/L Antinuclear antibody, serum positive: titer of greater than, equal to 1:160 Bicarbonate, serum 23-28 meq/L (23-28 mmol/L) Bilirubin, serum Total 0.3-1.2 mg/dL (5.1-20.5 mol/L) Direct 0-0.3 mg/dL (0-5.1 mol/L) Blood gases, arterial (patient breathing room air) pH - 7.38-7.44 Pco2 - 35-45 mm Hg Po2 - 80-100 mm Hg Oxygen saturation 95% or greater Blood urea nitrogen 8-20 mg/dL (2.9-7.1 mmol/L) Calcium, serum 9-10.5 mg/dL (2.2-2.6 mmol/L) Carbon dioxide content, serum 23-28 meq/L (23-28 mmol/L) Chloride, serum 98-106 meq/L (98-106 mmol/L)

Cholesterol, plasma Total 150-199 mg/dL (3.88-5.15 mmol/L), desirable Low-density lipoprotein (LDL) Less than or equal to 130 mg/dL (3.36 mmol/L), desirable High-density lipoprotein (HDL) Greater than or equal to 40 mg/dL (1.04 mmol/L), desirable Complement, serum C3 55-120 mg/dL (550-1200 mg/L) Total (CH50) 37-55 U/mL (37-55 kU/L) Creatine kinase, serum 30-170 U/L Creatinine, serum 0.7-1.3 mg/dL (61.9-115 mol/L) Electrolytes, serum Sodium 136-145 meq/L (136-145 mmol/L) Potassium 3.5-5.0 meq/L (3.5-5.0 mmol/L) Chloride 98-106 meq/L (98-106 mmol/L) Bicarbonate 23-28 meq/L (23-28 mmol/L) Fibrinogen, plasma 150-350 mg/dL (1.5-3.5 g/L) Folate, red cell 160-855 ng/mL (362-1937 nmol/L) Folate, serum 2.5-20 ng/mL (5.7-45.3 nmol/L) Glucose, plasma Fasting, 70-100 mg/dL (3.9-5.6 mmol/L) -Glutamyltransferase, serum 0-30 U/L Homocysteine, plasma Male: 4-16 mol/L; female: 3-14 mol/L Immunoglobulins IgG - 640-1430 mg/dL (6.4-14.3 g/L) IgA - 70-300 mg/dL (0.7-3.0 g/L) IgM - 20-140 mg/dL (0.2-1.4 g/L) IgD - Less than 8 mg/dL (80 mg/L) IgE - 0.01-0.04 mg/dL (0.1-0.4 mg/L) Iron studies Ferritin, serum 15-200 ng/mL (15-200 mg/L) Iron, serum 60-160 g/dL (11-29 mol/L) Iron-binding capacity, total, serum 250-460 g/dL (45-82 mol/L) Transferrin saturation 20%-50% Lactate dehydrogenase, serum 60-100 U/L Lactic acid, venous blood 6-16 mg/dL (0.67-1.8 mmol/L) Lipase, serum Less than 95 U/L Liver studies, serum Alkaline phosphatase 36-92 U/L Aminotransferase, alanine (ALT) 0-35 U/L Aminotransferase, aspartate (AST) 0-35 U/L Bilirubin Total 0.3-1.2 mg/dL (5.1-20.5 mol/L) Direct 0-0.3 mg/dL (0-5.1 mol/L) Magnesium, serum 1.5-2.4 mg/dL (0.62-0.99 mmol/L) Methylmalonic acid, serum 150-370 nmol/L Osmolality, plasma 275-295 mosm/kg H2O Phosphatase, alkaline, serum 36-92 U/L Phosphorus, serum 3-4.5 mg/dL (0.97-1.45 mmol/L) Potassium, serum 3.5-5.0 meq/L (3.5-5.0 mmol/L) Protein, serum Total 6.0-7.8 g/dL (60-78 g/L) Albumin - 3.5-5.5 g/dL (35-55 g/L) Globulins - 2.5-3.5 g/dL (25-35 g/L) Prostate-specic antigen, serum optimal less than 4 ng/mL Rheumatoid factor less than 40 U/mL (less than 40 kU/L) Sodium, serum 136-145 meq/L (136-145 mmol/L) Transferrin saturation 20%-50% Triglycerides Less than 250 mg/dL (2.82 mmol/L), desirable

Troponins, serum Troponin I 0-0.5 ng/mL (0-0.5 g/L) Troponin T 0-0.10 ng/mL (0-0.10 g/L) Urea nitrogen, serum 8-20 mg/dL (2.9-7.1 mmol/L) Uric acid, serum 2.5-8 mg/dL (0.15-0.47 mmol/L) Vitamin B12, serum 200-800 pg/mL (148-590 pmol/L)

Vanillylmandelic acid, urine Less than 8 mg/24 h (40.4 mol/24 h) Vitamin D 1,25-dihydroxy, serum - 25-65 pg/mL (60-156 pmol/L) 25-hydroxy, serum - 15-80 ng/mL (37-200 nmol/L)

Endocrine
Adrenocorticotropin (ACTH), serum 9-52 pg/mL (2-11 pmol/L) Aldosterone, serum Supine - 2-5 ng/dL (55-138 pmol/L) Standing - 7-20 ng/dL (194-554 pmol/L) Aldosterone, urine 5-19 g/24 h (13.9-52.6 nmol/24 h) Catecholamines Epinephrine, plasma (supine): less than 75 ng/L (410 pmol/L) Norepinephrine, plasma (supine): 50-440 ng/L (296-2600 pmol/L) Catecholamines, 24-hour, urine Less than 100 g/m2 per 24 h (591 nmol/m2 per 24 h) Cortisol, free, urine less than 90 g/24 h (248 nmol/24 h) Dehydroepiandrosterone sulfate (DHEA), plasma Male: 1.3-5.5 mg/mL (3.5-14.9 mol/L) Female: 0.6-3.3 mg/mL (1.6-8.9 mol/L) Epinephrine, plasma (supine): less than 75 ng/L (410 pmol/L) Estradiol, serum Male: 10-30 pg/mL (37-110 pmol/L); Female: day 1-10, 50-100 pmol/L; day 11-20, 50-200 pmol/L; day 21-30, 70-150 pmol/L Follicle-stimulating hormone, serum Male (adult): 5-15 mU/mL (5-15 U/L) Female: follicular or luteal phase, 5-20 mU/mL (5-20 U/L); midcycle peak, 30-50 mU/mL (30-50 U/L); postmenopausal, greater than 35 mU/mL (35 U/L) Growth hormone, plasma After oral glucose, less than 2 ng/mL (2 g/L); response to provocative stimuli: greater than 7 ng/mL (7 g/L) Luteinizing hormone, serum Male: 3-15 mU/mL (3-15 U/L) Female: follicular or luteal phase, 5-22 mU/mL (5-22 U/L); midcycle peak, 30-250 mU/mL (30-250 U/L); postmenopausal, greater than 30 mU/mL (30 U/L) Metanephrine, urine Less than 1.2 mg/24 h (6.1 mmol/24 h) Norepinephrine, plasma (supine): 50-440 ng/mL (296-2600 pmol/L) Parathyroid hormone, serum 10-65 pg/mL (10-65 ng/L) Prolactin, serum Male: less than 15 ng/mL (15 mg/L); Female: less than 20 ng/mL (20 mg/L) Testosterone, serum Male (adult): 300-1200 ng/dL (10-42 nmol/L) Female: 20-75 ng/dL (0.7-2.6 nmol/L) Thyroid function tests (normal ranges vary) Thyroid iodine (131I) uptake - 10% to 30% of administered dose at 24 h Thyroid-stimulating hormone (TSH) - 0.5-5.0 U/mL (0.55.0 mU/mL) Thyroxine (T4), serum Total - 5-12 g/dL (64-155 nmol/L) Free - 0.9-2.4 ng/dL (12-31 pmol/L) Free T4 index - 4-11 Triiodothyronine, resin (T3) - 25%-35% Triiodothyronine, serum (T3) - 70-195 ng/dL (1.1-3.0 nmol/L)

Urine
Albumincreatinine ratio less than 30 mg/g Calcium 100-300 mg/24 h (2.5-7.5 mmol/24 h) on unrestricted diet Creatinine 15-25 mg/kg per 24 h (133-221 mmol/kg per 24 h) Creatinine clearance 90-140 mL/min (0.09-0.14 L/min) 5-Hydroxyindoleacetic acid (5-HIAA) 2-9 mg/24 h (10.446.8 mol/24 h) Proteincreatinine ratio less than, equal to 0.2 mg/mg Sodium 100-260 meq/24 h (100-260 mmol/24 h) (varies with intake) Uric acid 250-750 mg/24 h (1.48-4.43 mmol/24 h) (varies with diet)

Gastrointestinal
Gastrin, serum 0-180 pg/mL (0-180 ng/L) Stool fat Less than 5 g/d on a 100-g fat diet Stool weight Less than 200 g/d

Pulmonary
Forced expiratory volume in 1 second (FEV1) greater than 80% predicted Forced vital capacity (FVC) greater than 80% predicted FEV1/FVC Greater than 75% (0.75)

Cerebrospinal Fluid
Cell count 0-5 cells/L (0-5 106 cells/L) Glucose 40-80 mg/dL (2.5-4.4 mmol/L); less than 40% of simultaneous plasma concentration is abnormal Pressure (opening) 70-200 cm H2O Protein 15-60 mg/dL (150-600 mg/L)

Hemodynamic Measurements
Cardiac index: 2.54.2 L/min/m2 Left ventricular ejection fraction: 45%70% Pressures: Pulmonary artery: Systolic: 2025 mm Hg Diastolic: 510 mm Hg Mean: 916 mm Hg Pulmonary capillary wedge: 612 mm Hg Right atrium: mean 05 mm Hg Right ventricle: Systolic: 2025 mm Hg Diastolic: 05 mm Hg

American College of Physicians

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