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Sri Ramakrishna Mission Vidhyalaya: PBG 201 Principles of Genetics and Cytogenetics

This document discusses genetic linkage, which describes how genes located close together on a chromosome tend to be inherited together. It violates Mendel's law of independent assortment. There are two types of linkage - complete and incomplete. Complete linkage means genes are always inherited together, while incomplete allows some non-parental combinations due to distant location on the chromosome. Genes showing linkage are arranged linearly on the same chromosome.

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0% found this document useful (0 votes)
63 views

Sri Ramakrishna Mission Vidhyalaya: PBG 201 Principles of Genetics and Cytogenetics

This document discusses genetic linkage, which describes how genes located close together on a chromosome tend to be inherited together. It violates Mendel's law of independent assortment. There are two types of linkage - complete and incomplete. Complete linkage means genes are always inherited together, while incomplete allows some non-parental combinations due to distant location on the chromosome. Genes showing linkage are arranged linearly on the same chromosome.

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sskr1307
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© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Sri Ramakrishna Mission

Vidhyalaya

PBG 201 Principles of Genetics and


Cytogenetics

Lecture - 20
Linkage
• Genetic linkage describes the way in which
two genes that are located close to each other
on a chromosome are often inherited
together
• This is phenomenon is not obeying the
Mendal’s law of independent assortment of
genes.
Eg. Maize – Seed color and seed shape
Drosophilla – Body color and wing type
Bateson and Punnet experiment
Coupling and Repulsion linkage
Chromosome Theory of Linkage
• Genes that show linkage are situated in the same
chromosome.
• Genes are arranged in a linear fashion in the
chromosome i.e., linkage of genes is linear.
• The distance between the linked genes is
inversely proportional to the strength of linkage.
• Linked genes remain in their original combination
during course of inheritance.
• The linked genes show two types of arrangement
on the chromosome. Cis arrangement (AB/ab)
and Trans arrangement (Ab/aB)
Types of Linkage
Depending upon the presence or absence of new
combinations or non-parental combinations, linkage can
be of two types
• Complete linkage
– If two or more characters are inherited together and
consistently appear in two or more generations in their
original or parental combinations, it is called complete linkage.
– These genes do not produce non-parental combinations.
Eg. Genes for grey body and long wings in male Drosophila
• Incomplete Linkage:
– Incomplete linkage is exhibited by those genes which produce
some percentage of non-parental combinations.
– Such genes are located distantly on the chromosome.
– It is due to accidental or occasional breakage of chromosomal
segments during crossing over.
Linkage group
• in genetics, all of the genes on a
single chromosome.
• They are inherited as a group; that is,
during cell division
• They act and move as a unit rather than
independently.

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