Contraception
Contraception
BP
MEC (medical eligibility criteria)
Most women who use contraception are fit and healthy.
However, some health conditions may be associated with real
or theoretical risks, (WHO) developed a system addressing
medical eligibility criteria for contraceptive use.
Category 1: A condition for which there is no restriction for
the use of the contraceptive method.
Category 2: A condition where the advantages of the method
generally outweigh the theoretical or proven risks.
Category 3: condition where the theoretical or proven risks
generally outweigh the advantages of using the method.
Category 4 : A condition that represents an unacceptable
health risk if the contraceptive method is used.
What a woman needs to know before starting a method of
contraception?
How to use the method (pill, patch or ring) and what to do
when misused (e.g. missed pill)
Failure rates
Common side-effects
Health benefits
Fertility return on stopping
When she need review?
Combined hormonal contraception
Methods contain two hormones: an oestrogen and a
progestogen.
They are available as oral pills, a transdermal patch and as a
vaginal ring.
Mechanism of action:
1. Work by inhibition of ovulation via negative feedback of
oestrogen and progestogen on the pituitary, with suppression
of follicle-stimulating hormone (FSH) and luteinizing
hormone (LH).
2. Thickening of cervical mucous to prevent sperm penetration.
3. Thinning of endometrium to prevent implantation.
Most of the commonly used COCPs are ‘low dose’ and contain
ethinyl oestradiol in a dose of 15–35 μg.
Failure rate about 0.1% correct use.
Absolute contraindication to COCPs:
1. Previous thrombosis
2. Ischemic heart disease
3. Cardiomyopathies
4. Smoking and age >35.
5. BMI > 40
6. BP >160/100
7. Severe diabetes mellitus
8. Focal migraine
9. Thrombophilia
10. 4 weeks before major surgery – 2 weeks after full mobility
11. Active liver disease
12. Severe inflammatory bowel disease
13. Undiagnosed genital tract bleeding / pregnancy.
14. Acute porphyria / SLE
15. Uncorrected valvular heart disease
16. TIAs / cerebral haemorrhage
17. Trophoblastic disease – until HCG undetectable.
18.Breastfeeding and <6 weeks postpartum.
19.Breast cancer.
Risk of VTE :
Healthy woman not taking COCP - 5 / 100,000
Second generation COCP user - 15 / 100,000
Third generation COCP user (desogestrel or gestodene) 25
/ 100,000
Pregnancy - 60 / 100,000
Non contraceptive uses of COCPs:
Dysmenorrhea.
Dysfunctional Uterine Bleeding
Anaemia.
Heavy menstrual bleeding
Irregular menses
Hirsutism, Acne.
Premenstrual syndrome
Reduces risk of ovarian cancer, endometrial cancer, colorectal cancer.
Benign breast conditions. .
Functional ovarian cysts
Ectopic pregnancy.
Missed pills:
If you have missed one pill, anywhere in the pack:
Take the last pill you missed now.
Continue taking the rest of the pack as usual.
If you have missed 2 or more:
In the 1st week
Take the missed pill, use condoms for next 7 days.
Ifunprotected intercourse emergency contraception should be
used.
In the 2nd week
Take the missed pill, use condoms for next 7 days.
In the last week
Omit the pill free interval, start new packet + condom for 7
days.
When to start taking pills?
From day 1-5 of the cycle.
Side effects:
Unscheduled bleeding and spotting.
Weight gain.
Breast tenderness and bloating.
Depression and loss of libido.
Hair loss, headache.
Cervical ectropion.
Progestogen-only contraceptive methods:
Progestogen-only methods are available as pills, injectable,
implant and intrauterine system.
mechanism of action of the method and the bleeding pattern
appear to depend on the dose of progestogen and also the route
of administration.
Progestogen-only pill (POP)
Acting by thickening of cervical mucous so prevent sperm
penetration.
Side-effects of all POPs include
possible irregular bleeding, persistent ovarian follicles (simple
cysts) and acne.
Window period is 3 hours.
Extra precautions (condoms) for the next 48 hours until the
progestogen effect on the mucus is built up.
Ifunprotected sex occurs during this time, then emergency
contraception is required.
Implants
containing the progestogen etonorgestrel 68mg.
Is a flexible rod, similar in size to a match stick and is
inserted subdermally 8 cm above the medical epicondyle,
usually of the non-dominant arm.
Insertion is conducted under local anaesthesia.
Duration 3 years.
Act by inhibit ovulation.
Can be used with breastfeeding .
Used in cases of menorrhagia and dysmenorrhea.
Cause amenorrhea.
Immediate return of fertility after removal.
Can be used in cases of ectopic.
SE: spotting and irregular vaginal bleeding.
Injections
Themost commonly used is a depot injection of
medroxyprogesterone acetate.
whichcan be administered intramuscularly as the formulation
Depoprovera (150 mg).
injection interval (every 12–14 weeks).
The injection is the only hormonal method that may delay
return of fertility after discontinuation, in some cases it may
take up to 1 year after the last injection for ovulation to return.
Cause amenorrhea up to one year.
Reduce bone mineral density.
weight gain.
Progestogen-releasing intrauterine system
The currently available intrauterine systems 52 mg LNG-IUS
(Mirena), levonorgestreal
Is licensed for 5 years for contraceptive use.
The LNG-IUS works by exerting a potent hormonal effect on
the endometrium, which prevents endometrial proliferation and
implantation. Its progestogenic effect on thickening the
cervical mucus also impedes entry of sperm.
NON-CONTRACEPTIVE USES
1- menorrhagia - up to 97%.
2-dysmenorrhoea.
3-PMS, HRT
4-low rate of ectopic pregnancy .
5-protection against PID.
6-management of endometrial hyperplasia.
SIDE-EFFECTS
Difficulties with insertion – especially in nulliparous
women.
Irregular bleeding.
Increased incidence of functional ovarian cysts.
Amenorrhoea.
Progestogenic side effects ( oedema / headache / breast
tenderness / acne )
Expulsion
copper intrauterine device Cu-IUD
Last 3-10 years.
Act by causing inflammatory reaction in the uterus, the
concentration of macrophages and leucocytes,
prostaglandins and various enzymes in both uterine and
tubal fluid increase significantly.
These effects are toxic to both sperm and egg and
interfere with sperm transport, and implantation is
inhibited.
Insertion of IUD
An IUD can be fitted at any point in the cycle provided
there is no risk of pregnancy.
Risk of perforation.
Risk of expulsion.
Infection.
Missing threads.
Barrier contraception
Condoms
Male condoms are cheap and widely available.
They protect against STIs including HIV.
The female condom is a lubricated condom that is inserted into the
vagina.
It also protects against STIs.
Diaphragm and cap
These are latex or non-latex devices that are inserted into the
vagina to prevent passage of sperm to the cervix.
Female sterilization
This is a permanent method of contraception that prevents sperm
reaching the oocyte in the Fallopian tube.
It can be performed by (1) laparoscopy, (2) hysteroscopy or (3)
laparotomy ( at caesarean section).
Advice to women considering sterilization
Method is considered as irreversible.
Failure rate 1:200 for laparoscopic.
Risks and complications (laparoscopic 1:1,000 risk of trauma to
bowel, bladder or blood vessels).
Vasectomy is safer, quicker, safer and with less morbidity.
High proportion of women regret sterilization.
Risk factors are age under 30 years, nulliparity, recent
pregnancy (birth, abortion, miscarriage) and relational issues.
Does not protect against STIs.
Risk of ectopic.
Vasectomy
This is the technique of interrupting the vas deferens to provide
permanent occlusion.
Involves a puncture wound in the skin of the scrotum under local
anaesthesia to access and then divide and occlude the vas using
cautery.
Post-vasectomy semen analysis should be conducted at 12 weeks to
confirm the absence of spermatozoa in the ejaculate.
Alternative contraception should be used until azoospermia is
confirmed.
The failure rate is significantly less than female sterilization at
approximately 1 in 2,000.
Lactational amenorrhoea
If a mother is within the first 6 months postpartum, is
amenorrhoeic and is fully or nearly fully breastfeeding, then the
risk of pregnancy is about 2%.
After 6 months, or if menses occur or breastfeeding reduced,
then another method of contraception must be used.
Emergency contraception
The most effective method of EC is an IUD (about 99%
effective).
An IUD can be inserted up to 5 days after ovulation for EC.
Ulipristal acetate (UPA) or levonorgestrel (LNG) are available
as oral methods of EC.
UPA can be given within 120 hours of unprotected intercourse.
LNG can be used within 96 hours of unprotected intercourse.
Effective ongoing contraception should be started after EC.