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Chapter 1

Genetics is the study of genes and how traits are passed from parents to offspring through chromosomes and DNA. The document traces the history and key discoveries in genetics from early ideas about inheritance to Mendel's foundational work to modern discoveries like the structure of DNA and the genetic code. It also outlines the levels, applications, and importance of genetics across various fields like health, agriculture, and ecology.

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Reigner Jay B. Escartin
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© © All Rights Reserved
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Download as PPT, PDF, TXT or read online on Scribd
168 views

Chapter 1

Genetics is the study of genes and how traits are passed from parents to offspring through chromosomes and DNA. The document traces the history and key discoveries in genetics from early ideas about inheritance to Mendel's foundational work to modern discoveries like the structure of DNA and the genetic code. It also outlines the levels, applications, and importance of genetics across various fields like health, agriculture, and ecology.

Uploaded by

Reigner Jay B. Escartin
Copyright
© © All Rights Reserved
Available Formats
Download as PPT, PDF, TXT or read online on Scribd
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Introduction to Genetics

Introduction to Genetics
Objectives:

Introduction
1.) determine to Genetics
the origin, scope, and
importance of Genetics and cytogenetics
2.) identify the levels of Genetics
3.) identify applications of Genetics and
cytogenetics
Genetics

• Genetics is the study of genes.


• Inheritance is how traits,
Introduction to or
Genetics
characteristics, are passed on from
generation to generation.
• Chromosomes are made up of genes,
which are made up of DNA.
• Genetic material (genes,chromosomes,
DNA) is found inside the nucleus of a cell.
History of Genetics

• People have known about inheritance for a


long time.
Introduction to Genetics
• --children resemble their parents
• --domestication of animals and plants,
selective breeding for good characteristics
• --Sumerian horse breeding records
• --Egyptian data palm breeding
• --Bible and hemophilia
Old Ideas

• Despite knowing about inheritance in


general, a number of incorrect ideas had to
Introduction
be generated to Genetics
and overcome before modern
genetics could arise.
• 1. All life comes from other life. Living
organisms are not spontaneously generated
from non-living material.
• 2. Species concept: offspring arise only
when two members of the same species
mate. Monstrous hybrids don’t exist.
• 3. Organisms develop by expressing information
carried in their hereditary material. As opposed
to “preformation”,
Introductionthe idea
to that in each sperm (or
Genetics
egg) is a tiny, fully-formed human that merely
grows in size.
• 4. The environment can’t alter the hereditary
material in a directed fashion. There is no
“inheritance of acquired characteristics”.
Mutations are random events.
• 5. Male and female parents contribute
equally to the offspring.
• Introduction
--ancient to Genetics
Greek idea: male plants a
“seed” in the female “garden”.
• --alleged New Guinea belief: sex is
not related to reproduction.
Mid 1800’s Discoveries

• Three major events in the


mid-1800’s led directly to
the development of
modern genetics.
• 1859: Charles Darwin
publishes The Origin of
Species, which describes
the theory of evolution by
natural selection. This
theory requires heredity to
work.
Introduction to Genetics

1866: Gregor Mendel publishes


Experiments in Plant
Hybridization, which lays out the
basic theory of genetics. It is
widely ignored until 1900.
Major Events in the 20th Century
• 1900: rediscovery of Mendel’s
work by Robert Correns, Hugo de
Vries, and Erich von Tschermak.

Introduction to Genetics
• 1902: Archibald Garrod discovers
that alkaptonuria, a human
disease, has a genetic basis.

• 1904: Gregory Bateson discovers


linkage between genes. Also
coins the word “genetics”.
1910: Thomas Hunt Morgan proves
that genes are located on the
chromosomes (using Drosophila).

Introduction to Genetics
1918: R. A. Fisher begins the study of quantitative
genetics by partitioning phenotypic variance into
a genetic and an environmental component.

1926: Hermann J. Muller shows


that X-rays induce mutations.

1944: Oswald Avery, Colin MacLeod and Maclyn


McCarty show that DNA can transform bacteria,
demonstrating that DNA is the hereditary material
• 1953: James Watson and
Francis Crick determine the
structure of the DNA molecule,
which leads directly to
knowledge of how it replicates

• 1966: Marshall Nirenberg solves


the genetic code, showing that 3
DNA basesIntroduction to
code for one amino Genetics
acid.

• 1972: Stanley Cohen and


Herbert Boyer combine DNA
from two different species in
vitro, then transform it into
bacterial cells: first DNA cloning.

• 2001: Sequence of the entire


human genome is announced.
Why genetics is
important?
Genetics

Introduction to Genetics
G×E
interaction

Environment Health
Scope of Genetics

Cytogenetics
Molecular to
Introduction Genetics
Genetics
Genomics
Classsical Genetics
Population Genetics
Genetics of Behavior
Biotechnology
Levels of Genetics

DNA Introduction to Genetics


Genes
Cells
Tissues
Organs
System
Individual
Family
Population Introduction to Genetics
Evolution
Applications of Genetics

Introduction to Genetics
Health Care
Agriculture
Ecology
Global Perspective
agriculture
Establishing Identity

Introduction to Genetics
Medicine/Health Care

Introduction to Genetics
Ecology

Introduction to Genetics
1. Eye-catching headline
of the form “Gene
for…”

2. Highly qualified factual


paragraph
Assignment: Clippings, short
bond paper, by pair

# Research news coverage on


natural disaster or act of
terrorism or war, or other
form of violence, abd
describe the roles of DNA in
profiling to identify the
victims.

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