Hyperkalemia
Hyperkalemia
• Causes
a) impaired urinary potassium excretion due to
acute or chronic kidney disease
b) drugs that inhibit the renin-angiotensin-
aldosterone axis eg ACE inhibitors eg
enalapril
CLINICAL MANIFESTATIONS
1) muscle weakness or paralysis,
2) cardiac conduction abnormalities, and
3) cardiac arrhythmias.
Diagnosis
a) Clinical features
b) ECG …..peaked T waves
c) Serum potassium …..more than 5.5
Treatment
1) Intravenous calcium to antagonize the
membrane actions of hyperkalemia eg iv
calcium gluconate 1g 10% 10ml
2) Intravenous insulin , rapid-acting , 10 units
with iv dextrose 50ml
3) Therapy to rapidly remove excess potassium
from the body eg diuretics or dialysis