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Inputs or Factors or Regulators: That Control Hormone Secretion

Inputs or factors that can affect the endocrine system and hormone secretion include aging, the environment, genetics, diseases, medications, stress, and certain lifestyle factors. Aging can alter hormone production, metabolism, levels, and target tissue response. Diseases may decrease the body's ability to break down hormones or cause endocrine defects. Environmental chemicals can mimic, block, or interfere with natural hormone processes. Genetics can impact the endocrine system through chromosomal abnormalities affecting hormone production or function.

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44 views13 pages

Inputs or Factors or Regulators: That Control Hormone Secretion

Inputs or factors that can affect the endocrine system and hormone secretion include aging, the environment, genetics, diseases, medications, stress, and certain lifestyle factors. Aging can alter hormone production, metabolism, levels, and target tissue response. Diseases may decrease the body's ability to break down hormones or cause endocrine defects. Environmental chemicals can mimic, block, or interfere with natural hormone processes. Genetics can impact the endocrine system through chromosomal abnormalities affecting hormone production or function.

Uploaded by

Abdul Moqeet
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PPTX, PDF, TXT or read online on Scribd
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Inputs or factors or Regulators

that control Hormone Secretion


Inputs or factors or Regulators that control Hormone Secretion

Everyone's body undergoes changes, some natural and some not,


that can affect the way the endocrine system works.

Some of the factors that affect endocrine organs include,


 aging,
 the environment,
 genetics
 and certain diseases
 and medications, including herbal supplements, and prescription
medicines such as steroids.
Aging
Despite age-related changes, the endocrine system functions well in
most older people. However,
some changes occur because of either damage to cells during the aging
process or medical issues, or genetically programmed cellular changes.

These changes may alter the following:


hormone production and secretion
hormone metabolism
hormone levels circulating in blood
target cell or target tissue response to hormones
rhythms in the body, such as the menstrual cycle
Diseases and Conditions
Chronic diseases and other conditions may affect endocrine system
function in several ways.
After hormones produce their effects at their target organs, they are
broken down (metabolized) into inactive molecules. The liver and
kidneys are the main organs that break down hormones. The ability of
the body to break down hormones may be decreased in people who
have chronic heart, liver, or kidney disease.

Abnormal endocrine function can result from:


congenital (birth) or genetic defects
surgery, radiation, or some cancer treatments traumatic (physical)
injuries
cancerous and non-cancerous tumors
infection
autoimmune destruction (when the immune system turns against the
body's own organs and causes damage)
medications
Stress
Physical or mental stressors can trigger a stress response.

The stress response is complex and can influence heart, kidney, liver,
and endocrine system function.

For the body to respond to, and cope with physical stress, the adrenal
glands make more cortisol. If the adrenal glands do not respond, this
can be a life-threatening problem.

Some medically important factors causing a stress response are:


trauma (severe injury) of any type
severe illness or infection
intense heat or cold
surgical procedures
serious diseases
allergic reactions
Environmental Factors
An environmental endocrine disrupting chemical (EDC) is a substance outside
of the body that may interfere with the  normal function of the endocrine
system.

Some EDCs mimic natural hormone binding at the target cell receptor. (Binding
occurs when a hormone attaches to a cell receptor, a part of the cell designed
to respond to that particular hormone.) EDCs can start the same processes that
the natural hormone would start.

Other EDCs block normal hormone binding and thereby prevent the effects of
the natural hormones.
Still other EDCs can directly interfere with the production, storage, release,
transport, or elimination of natural hormones in the body. This can greatly
affect the function of certain body systems.
Genetics

Your endocrine system can be affected by genes.


Sometimes extra, missing, or damaged chromosomes can result in
diseases or conditions that affect hormone production or function.

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