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DR - Kima Presentation

This document provides information on common medicines stocked in a department and available locally, including antibiotics, dosages, and treatment practices. It discusses several classes of antibiotics like penicillin (cell wall inhibitor), cephalosporins, tetracyclines (protein synthesis inhibitors), and aminoglycosides. For each class, it describes their mechanism of action, spectrum of activity, side effects, contraindications, example drugs, and dosages by animal. Brand names of drugs from each class that are commonly used are also listed.

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0% found this document useful (0 votes)
67 views49 pages

DR - Kima Presentation

This document provides information on common medicines stocked in a department and available locally, including antibiotics, dosages, and treatment practices. It discusses several classes of antibiotics like penicillin (cell wall inhibitor), cephalosporins, tetracyclines (protein synthesis inhibitors), and aminoglycosides. For each class, it describes their mechanism of action, spectrum of activity, side effects, contraindications, example drugs, and dosages by animal. Brand names of drugs from each class that are commonly used are also listed.

Uploaded by

dvo aizawl
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPTX, PDF, TXT or read online on Scribd
You are on page 1/ 49

COMMON MEDICINES STOCKED IN THE

DEPARTMENT AND AVAILABLE IN THE LOCAL


MARKET WITH DOSAGES FOR TREATMENT
PRACTICES

Presented by,
Dr. P.C. Lalrokima
ANTIBIOTICS???
Antibiotics kan tih chuan natna hrik (micro-
organisms) thenkhat thahna emaw than tih thut
nana natna hrik dang atanga chemical chikhat an
lak chhuah kan ti thei awm e.
Antibiotics te hi an hnathawh dan a zirin chi hrang
hrangah an in then hrang veleh a, chungte chu:

1.Cell wall inhibit tu te:


e.g: Penicillin,cephalosporins,cycloserine,vancomycin,etc
2.Cytoplasmic membrane function inhibit tu te:
e.g: Polymyxins,amphotericin B leh nystatin
3.Protein synthesis inhibit tu te:
e.g: Chloramphenicol,tetracyclines,macrolides and
aminoglycosides
4.Nucleic acid metabolism leh synthesis tibuaitu te:
e.g: Quinolones,acyclovir,rifampicin,etc.
5.Intermediary metabolism tibuaitu te:
e.g: Sulphonamides,trimethoprim leh sulphones te.
KAN HMAN THIN LANGSAR
ZUAL THENKHAT TE:
Penicillin (CELL WALL INHIBITOR)
Hei hi gram +ve bacteria te thahnana hman deuh bik an
ni a, gram –ve tan erawh chuan a tha em emlo, a chhan chu
heng gram –ve bacteria te hi chuan capsule leh outer
lipopolysaccharide membrane cell wall chunga tuamtu an
neih tlat a vangin duh angin penicillin drugs te hian hna
an thawk thei ta thin lo a ni.
Tin, mycobacterium,fungi,protozoa leh virus te hi cell
wall nei ve lo an nih avangin Penicillin drugs te hmang
hian thah theih an ni ve lo.
Side Effects:
Hypersensitivity kan tih te, pumpui lam harsatna te,
platelet dysfunction te,Cation toxicity kan tih te,Organ
toxicity kan tih te a thlen thei a ni.
Contraindications:
Hypersensitive patient

P.S: Bacteriostatic drugs te nen hman pawlh loh tur an ni.


Penicillin group of drugs Dose leh Route te:

Pg 49
Brand name hman langsar zual thenkhat te:
Dicrysticin, FPP, Bistrepen, Pendistrin-SH, Munamycin, Dicrysticin LD,
Inclox, Ciclox, Vetclox, AC Vet, AC Vet forte, Nepoclox,Bacipen, Hipenox,
Colampi, Catcillin, Solampi, Intamox D, Moxel D, Intamox Z,
Amoxirum,etc..
CEPHALOSPORINS (Cell Wall Inhibitor)
1st generation: Moderate spectrum niin heng E.coli,
Klebsiella pneumoniae & Proteus mirabilis natna hrik
hovina an thlen ho natna hrik thah nan an hman theih a,
amaherawhchu Bacteriodes fragilis, Enterococci,
methicillin-resistant staphylococci, Pseudomonas,
Acinetobacter, Enterobacter, indole-positive Proteus or
Serratia.
e.g: Cephalexin,ceftezole,cefazolin,cefatrizine,etc.
2nd generation: Gram –ve bacteria natna hrik thahnan
an tha em em a,tin gram +ve cocci natna hrik ho thah nan
pawn an hman tlak tho bawk. B-lactamase enzyme kan tih
natna hrik tena B-lactam antibiotics ho an lo do let
theihna enzyme chikhat lakah pawh resistant an nei tha
hle.
3rd generation:
Broad spectrum niin CNS lut tlang(penetrate) thei an
ni a, heng natna hrik Pneumococci, meningococci,
H.influenza, E.coli, Klebsiella leh penicillin resistant
N.gonorrhoeae te thahnan hian an tha in,meningitis
gram-ve natna hrik in a thlen bikah phei chuan drug of
choice an ti hial a ni.
Side effects:
Allergy, kal thalo etc.
Cephalosrorin group of drugs Dose leh Route te:

Pg 57
Brand name hman langsar zual thenkhat te:
Vetaceph, Intacef, Macef, Moxef, X-ceft, TT-ceft,
Xonecef, Xonexef, Exact, Ceft-one, Zydaceft, Intacef
Tazo, Britax, Cefatox, Vetaxim,Cefavet, M-ceft,Cefatin,
Cephatin Sulbactam,Lixen bolus,Ladexin,Malexin,
etc.
Tetracycline (Protein synthesis inhibitor)
An hnathawh dan tlangpui:
1.Bacterial(natna hrikte) cell wall ah passive emaw active transport
hmangin an lut .
2. Interaction with bacterial ribosome
Cell wall an kal tlang hnu chuan 30S ribosome ah va belhbawm in m-
RNA complex-a acceptor A site a aminoacyl –tRNA va inbelhbawm tur chu
tibuai tlatin,natna hrik a protein synthesis lo awm tur chu a dang ta tlat thin
a ni.
Natna hrik inthlahpung chak tak that nan an tha in pH6-6.5 ah hna an
thawk chak zual thin.
Broad spectrum an ni a, anaerobic leh aerobic G-ve&
G+ve te, mycoplasma, rickettsia, chlamydia leh protozoa
thenkhat thah nan an hman theih a, amaherawhchu fungi
leh virus natna hrik thah nan erawh chuan an hman tlak
loh a ni.

Side Effects:
Pum nuamlo, ruh leh ha ah ngawng a nei thei, thin
lamah hasatna te, kal thalo te a thlen thei.
Contraindication:
Oral route in Sakawr, Ruminants ah pekloh tur,
Rai lai ah leh ran no kar 4 hnuai lamah pek loh tur.
Tetracycline group of drugs dose leh route te:
Drugs Animal Doses Route Interval
Oxytetracycline Dogs & Cats 5-10 mg/kg SC or IM 1-2 times
Cattle/Sheep/ 20 mg/kg PO 3 times
Goats/Pigs 5-10mg/kg IM/Slow IV Once
Horses 20 mg/kg IM (depot) Repeat after 2-4 days
Poultry 5 mg/kg Slow IV 1-2 times
10-25mg/kg 100 litres drinking water ----------

Tetracycline Dogs & Cats 20mg/kg PO 3 times


Cattle/Sheep 7mg/kg IM or IV 2 times
Horses 10mg/kg PO 2 times upto 5 days
Pig 5-7.5 mg/kg IV 2 times
Poultry 40 mg/kg PO (dinking water) once
60mg/kg -do- -do-

Chlortetracycline Cattle & Pig 10-20 mg/kg PO Daily


Pigs 400-600g/tonne PO Once
Poultry (feed) PO Once
Turkey & 20-50 mg/kg PO
Ducks 300-400g/tonne
10-30g/kg
Doxycycline Dog & Cat 5-10 mg/kg PO or IV Once
Birds 15-25 mg/kg PO 2 times
130mg/litre

Minocycline Dog 12.5-25mg/kg PO 2 times


Cat 12.5 mg/kg IV 2 times
5-15mg/kg PO 2-3times
Brand name hman langsar zual thenkhat te:
Oxy LA, Oxyvet,Loxy,Intamycin, IntamycinLA, Oxymac,
Steclin,Oxy Vet, Loxy, etc.
AMINOGLYCOSIDES (Protein synthesis inhibitor)
An hnathawh dan tlangpui te:
1.Cell wall an cross.
2.Cell membrane an cross leh.
Hei hi oxygen dependent process niin electron transport chain nen a
inzawm tlat a,chuvang chuan anaerobic natna hrik te chuan an resist tlat
thin.Tin,pH sang tak an mamawh bawk.
3.Bacterial (natna hrik) ribosomes ah lutin 30S leh 50S ah a va belhbawm
a,chuchuan Distortion m-RNA codon ah thlenin Codon Misreading a thlen
ta thin a ni.
Hengte avang hian RNA te chu puitling thei lovin protein synthesis te
chu a lo buai ta thin a,he mechanism hmang hian natna hrik te chu a that ta
thin a ni.
An spectrum a zirin then hran an ni ve leha:
a) Narrow-spectrum aminoglycosides
e.g., streptomycin and dihydrostreptomycin.
b) Broad-spectrum aminoglycosides.
e.g., neomycin, framycetin, kanamycin and paromomycin.
c) Extended spectrum aminoglycosides
e.g., gentamicin, amikacin, tobramycin, sisomicin and netilmicin.
Side effects:
Kal lama harsatna te,ri hriatna lama harsatna te,hriatna thazam
lama harsatna te a thlen thei.
Contraindications:
Myasthenia gravis natna nei ah hman loh tur,kal tha lo emaw ran no
ah pek loh hram a tha.
Working dogs kan tih hovah hian a tul fe anih loh chuan pek loh tur
ani.
Practitioner thenkhat chuan zawhte ah toxicity risks a san avangin
an hmang ngai lo bawk.
Aminoglycosides group of drugs Dose leh Route te:
Drugs Animal Dose Frequency

Enteric infection:
Dogs & other spp 15mg/kg PO Once daily
Systemic infection:
Streptomyci Dogs 5-10mg/kg IM -do-
n Cattle, sheep, goat & 10mg/kg IM -do-
horses

Enteric: dog & cat 10mg/kg PO Divided dose


Cattle 10-20 mg/kg PO 2 times a day
Horse 5-15 mg/kg PO Once
Neomycin Pigs 230g/tonne feed or daily
12.5g/100 litres of drinking water
Poultry 10mg/kg PO
230g/tonne feed

Eneteric: as
Framycetin/ neomycin 5mg/kg Im 2 times a day
Neomycin B Acute mastitis

Kanamycin Dogs & Cats 5-7.5mg/kg Im or Sc 2-3 times/day


Dog & Cat 5mg/kg IM or SC 2 times (1st day) & once daily
Cattle 2.5-5mg/kg IM 2-3 times
Horse 2-4 mg/kg IM -do-
Swine 1.1-2.2mg/kg/day in water 3 days
(colibacillosis) 200-250 ml(2%)
Gentamicin intrauterine Once daily (3 days)
Cows & Mares
(metritis)

Dog & Cat 5-10mg/kg IM or SC 2-3 times


Cattle 10mg/kg IM 3 times
Horse 6.6mg/kg IM or IV 3-4 times
Mare: metritis 2% in NS, intrauterine Once for 3 days
Amikacin Birds 15mg/kg IM or SC 2 times

Dog & Cat 4-6mg/kg IM, SC, slow IV 2-3 times


Horse 1-1.5mg/kg IM or slow IV 3 times
Tobramycin Birds 5mg/kg IM 2 times
Brand name hman langsar zual thenkhat te:
Akayci,Amikacin,Legenta, Gentamicin, Progenta, Bistrepen,
Pendistrin-SH ,etc.
CHLORAMPHENICOL(Protein synthesis Inhibitor)

An hnathawh dan tlangpui te:


50S ribosomal sub unit ah belhbawmin peptidase transferase enzyme
hnathawh a tibuaiin transpeptidation kan tih thin kha a awm thei ta lova
protein synthesis kha natna hrik te chuan an performed thei ta thin lova ni.

Broad spectrum an niiin heng natna hrik gram+ve organisms te, gram-
ve organisms te, aerobic leh anaerobic organisms te, Rickettsiae,
Psittacosis te, nocardia te, chlamydia leh mycoplasma ho vin a an thlen
natna enkawlnan te hian an hman theih thin a ni.
Side effects:
Hypersensitive reaction ui leh zawhte ah, Bone marrow depression(Host mitochondrial
protein synthesis inhibit vangin), Aplastic anaemia,Hypoplastic anaemia, Agranulocytosis,
thrombocytopenia te a thlen thei. Tin, pumpui lamah harsatna thlen
theiin,luhai,luakchhuak,kawthalo a siam thei bawk. Lung lamah pawh harsatna a thlen thei thin
bawk.

Contraindication:
Zawhte ah hman loh hram a tha,achhanchu Glucoronide conjugation an tlakchham a vangin
an taksa in a paihchhuak tha thei thin lo.
Ran no ah emaw pianghlimah hman loh a him,a chhan chu ran nopang lutukah chuan thin ah
glucoronyl transferase in duhthusamin hna a la thawk ve thei lo va,tin kal in duh angin taksa
atangin a paih chhuak thei thin lo bawk avangin.
P.B: Macrolide antibiotics te nen hman pawlh loh tur an ni (an hnathawh na,bacterial ribosome a
an va belhbawmna site a in ang 50S ve ve an nih avangin), B-lactam antibiotics te nen pawn
hman pawlh loh tur. Tin, Ruminants ho vah Oral route in pek loh tur (a chhanchu ruminal micro
flora ten awlsam takin p-nitro reduction an lo thlen thin a ni)
Chloramphenicol group of drugs Dose leh route te:
Oral route:
Chloramphenicol palmitate:
Calves leh Foal ah 0.50g BID or TID
Piglet leh lambs ah 0.25g BID or TID
Dogs165mg/kg daily in 3 divided doses
Cats0.25g OD or BID
Intramuscular route:
Chloramphenicol sodium succinate:
Large animals2-4mg/kg
Small animals4-10mg/kg
Intravenous route:
Chloramphenicol sodium succinate: 40% solution
Fluoroquinolones
Hemi group a antibiotics ho hi chuan Supercoiling DNA
kan tih mai natna hrikin a neih te chu DNA gyrase
hmangin an tidanglama,tichuan awlsam takin natna hrik
te chu a tichhe ta thin ani.
Fluoroquinolones group of drugs hman theih na
tlangpuite:
Spectrum of Fluoroquinolone Activity
  Pathogen
Gram- Gram- Anaerobic* Pseudo- Atypical† STD
positive negative monas species organ-
isms‡
Drug
Ofloxacin + +++ 0 ++ +++ +++
Ciprofloxacin + ++++ 0 ++++ ++§ ++§
Levofloxacin ++" +++ + +++ +++ +++
Sparfloxacin ++" +++ + 0 +++ +++
Gatifloxacin ++" +++ + ++ +++ +++
Moxifloxacin ++" +++ ++ ++ +++ +++
Trovafloxacin ++" +++ +++ ++ +++ +++
* Only moxifloxacin and trovafloxacin produce reliable anaerobic activity.
† Includes Legionella pneumophila, Mycoplasma pneumoniae and Chlamydia pneumoniae.


Includes Neisseria gonorrhea, Mycoplasma hominis, Chlamydia trachomatis, and Ureaplasma urealyticum.

§ Not reliably active against Chlamydia trachomatis or Chlamydia pneumoniae.

"
Activity against streptococci is enhanced; may be active against some isolates of MRSA and enterococci.
Side effects/Main toxicity:
Pumlam harsatna- luhai luakchhuak, pumna, kawthalo
CNS pawh effect tel theiin,luna,luhai leh muthilh that
theih lohna a thlen thei.
Arthropathy- Ran no leh thanglaiah ruhchuktuah ah
erosion thlenin ruhchuktuah na a thlen thei a, heavy
breeds ho leh intlansiakna atana hman sakawrah te phei
chuan hman loh tur a ni.
Kal lam thalo te,Cataract te a thlen thei
Phototoxicity/Dermal toxicity a thlen thei(a bikin
lomefloxacin leh sparfloxacin a hlauhawm zual)
Lung thalo leh thin lamah harsatna thlen thei
Mutagenicity
Embryotoxicity
Brand name hman langsar zual thenkhat te:
Cflox power, Cflox-Tz, Ciprovet-Tz, Cflox U, Curacin Tz ,Marbomet tablet,
Curacin,etc.

Dose: Ciproflxacin LA- 4-5mg/kg


Dog&Cat- 5-15mg/kg
Ofloxacin LA- 30mg/day×3-5 days
MA- 0.5mg/day×3-5 day
Dog&Cat- 3-4mg/day
Macrolides(Protein synthesis Inhibitor)
He antibiotics pawh hian natna hrika 50S ribosomal subunit ah chuan bei
tlatin translocation awm tur vengin natna hrik than ti thu in zawi zawiin a tihlum ta
thin a ni.
Bactericidal emaw bacteriostatic a concentration leh natna hrik a zirin a ni
thei.
Antibacterial spectrum
Narrow spectrum,natural penicillin te nen a compare theih

Erythromycin- Gram positive leh spirochetes natna hrik thahnan a hman theih a,
mahse gram negative bacteria natna hrik tan erawh a hman tlak loh.

Azithromycin- Gram positive bacteria natna hrik thah nan a hmantheih tho a,
mahse heng natna hrik H. influenzae leh H. legionella thahnan hian a tha in
Toxoplasma gondii natna hrik thahnan phei chuan duhthusam a ni.

Clarithromycin- active tak a niin a metabolite phei chu erythromycin aiin a


lethnihin H. influenzae natna hrik thahnan a tha zawk a.Tin, Mycobacterium avium
cellulare natna hrik thahnan pawn a tha hle a ni.
Side Effects:
Pum nuamlo (luakchhuak, chawei theilo, kawthalo, etc) a thlen thei a,tin
superinfection te pawh a thlen thei bawk
Erythromycin-hypersensitivity reactions (allergy,khawsik, ri hriatna lama
harsatna,leh thin lian te thleng in hman dan a dik tawk loh chuan a thlen thei
bawk.
A jection na laiah na deuh leh vung te pawh a thlen thei.
Contraindications:
Hypersensitive patients ah hmanloh tur
Thin lam harsatna neisaah hman loh tur
Hnute tui sawrlai emaw hnute pe lai ah hmanloh tur,a chhan chu bawnghnute
ah a concentration a sang thei em em a ni.
Do not produce teratogenic effect, but its use in pregnant animal may be done
cautiously.
Railaiah hman in fimkhur taka hman tur ani.
Chloramphenicol leh Lincosamide drugs te nen hman pawlhloh tur ani.
Preparations & Dosage
Oral dose in Non-herbivores : 6.6-8.8 mg/kg/day (in 3-4 divided
doses)
Erythromycin stearate : 4.4-6.6 mg/kg/day (in 3-4 divided doses)
Erythromycin lactobionate : 2.2-4.4 mg/kg at 8-12 hr interval
.
LINCOSAMIDES
A hnathawhdan tlangpui te:
Natna hrika Protein synthesis awm tur inhibit tlatin, macrolides leh
chloramphenicol te nen natna hrika ribisome ah an va inbelhbawmna( binding
site) 50-S ribosomal subunit a in ang ani.
Bacteriostatic drugs a ni a,chloramphenicol leh macrolides, te nen an binding
site a in an avangin an in compete thin a,chuvang chuan hman pawlh tur an ni lo
ani.
Spectrum:
G-ve aiin G+ve bacteria natna hrikho thahnan an tha zawk.
Tin,aerobic organisms ho aiin anaerobic organisms ho
thahnan an tha zawk bawk
Lincosamide drugs ho hi Toxoplasma leh Mycoplasma
natna hrik thenkhat thahnan an tha hle.

Clindamycin ho te hi an huap zau deuh zawkin G-ve


anaerobic natna hrik thahnan an tha hle bawk ani.
Side effects:
Pum lam harsatna(kawthalo,luakchhuak leh chawei tuilohna)
Ruminants ho te, sakawr te, sazu leh mihringah te pseudomembraneous colitis a
thlen palh thei
Neuromuscular transmission inhibit tlatin skeletal muscle(tihrawl) ah zenna a
thlen thei bawk
Hypersensitive reaction emaw na jectionna laiah a thlen palh thei bawk.
Doses:
Lincomycin:
Dogs & cats :
20mg/kg PO b.i.d
20mg/kg IM once
10-20 mg/kg slow IV 1-2 times
Cattle:
10mg/kg IM b.i.d
Pigs:
10 mg/kg IM once
110 g/tonne feed
3.3 g/100 L of water

Clindamycin:
Dogs & Cats:
5-10 mg/kg PO b.i.d
10 mg/kg IM b.i.d
SULFONAMIDES
Pteridine + PABA
A hnathawh dan tlangpuite
Dihydropteroate
SULFONAMIDES
Dihydropteroic acid
Synthase
Glutamic acid

Dihydrofolic Acid

TRIMETHOPRIM
Dihydrofolate
Tetrahydrofolic Acid
Reductase

Tetrahydrofolate
Purines Thymidine Methionine,
Reductase Glycine

DNA DNA, RNA Proteins


Antibacterial spectrum
Baggot and Prescott (1993) aten a hnuaia mi ang te hiannatna hrik thahnana
an effective dan a zirin an lo then hranga:
1. Good susceptibility
 Actinomyces spp.
 Bacillus spp.
 Brucella spp.
 E. rhusiopathie
 Streptococcus spp.
 Chalnydia spp.
 Pneumocystic carinii
 Cryptosporidum spp.
2. Moderate susceptibility
 Gram-positive aerobes (Ataphylococcus, Enterococci etc.)
 Gram-negative aerobes (Enterobacter spp., E. coli, Klebsiella spp., Proteus spp., Actnobacillus
spp., Hemophilus spp., Pasteurella spp., Pseudomonas spp. Etc.)
 Others including Actinomyces spp., Bacteroides, Fusabacterium spp. And some Clostridium
spp.
3. Resistant
 Mycobacterium spp., Mycoplasma spp., Rickettsiae spp., P. aeroginosa and Spirochetes.
Tin a hun hman rei zawng a zirin a hnuaia mi te ang hian then hran an ni bawk:
1. Systemically acting sulphonamides:
1. Short acting sulfonamides (duration <12 hrs)
e.g., Sulphadiazine, sulphisoxazole, sulphamerazine,
sulphachlorpyridazine, sulphathiazole, sulphanilamide, sulphapyridazine
and sulphasomidine.

2. Intermediate acting sulfonamides (duration 12-24 hrs)


e.g., sulphadimidine, sulphamethoxazole, sulphamoxole and
sulphaphenazole.

3. Long acting sulfonamides (duration 24-48 hrs)


e.g., Sulphabromomethazine, sulphadimethoxine,
sulphaethoxypyridazine and sulphamethoxypyridazine.

4. Ultra-Long acting sulphonamides (duration >48 hrs)


e.g., Sulphadoxine and sulphamethopyrazine.

2. Locally acting sulphonamides:


1. Gut-acting sulphonamide
e.g., Succinylsulphathiazole, phthalylsulphathiazole,
phthalylsulphacetamide, sulphaguinidine and sulphasalazine.

2. Topically acting sulphonamide


e.g., sulphacetamide, mafenide and silver sulphadiazine.
Antagonism (A hnuaia kan tarlan te an awm hian a
damdawi hnathawh hi a nih tur angin a thawhtir thei lo)

PABA a awmin emaw drugs engpawh PABA pe chhuak


thin an awmin e.g., procaine (LA) and procaine penicillin.

Vit. B complex, niacin,folic acid ,choline leh amino acids


kan tih glutamic acid leh methionine an awmin.

Gelatine, Albumin leh peptone an awmin,a chhanchu


heng te hi Sulfa drugs ah hian an bind theiin damdawi
hnathawh an ti thuanawp thin a ni.

Pan chhia leh hnai te pawhin an hnathawh a ti thuanawp


thei bawk.

P.B: Trimethoprim group te nen hman pawlh thin an ni tlangpui.


Short Acting

Sulphadiazine Cattle 100mg/kg IV


Calves 30mg/kg IV
Pigs 40mg/kg PO
20mg/kg IV

Sulphasixazole Dogs & Cats 50mg/kg PO 3 times daily

Sulphamerazine Sheep 60-100mg/kg IV


100mg/kg PO

Sulphachlorpuridazine Cattle 30mg/kg PO 3 times daily


Swine 100mg/kg IV 1-2 times daily
44-77 mg/kg PO once daily

Sulphathiazole Sheep 36-72 mg/kg IV


Swine 200mg/kg IV

Intermediate Acting

Sulphadimidine Cattle & Sheep 200mg/kg SC or IV (initial dose) follwd by 100mg/kg once daily
Pigs 20-50mg/kg IV or PO once daily

Sulphamethoxazole Dogs & Cats 100mg/kg PO (loading) follwd by 50mg/kg PO 2times daily

Long Acting

Sulphadimethoxine Dogs & Cats 25-50mg/kg PO, IV, SC/day


Cattle 50-100 mg/kg PO, IV Once
Horse 50mg/kg PO, IV twice

Sulphamethoxypyridaxine Cattle & Sheep 20mg/kg IV, SC or IM once

Sulphaethoxypyridazine Cattle 55mg/kg PO

Sulphabromomethazine Cattle 150-200 mg/kg PO

Gut Acting

Phthalylsulphathiazole Dogs & Cats 100mg/kg PO 2 times

Phthalylsulphacetamide Calves 350-500mg/kg PO


Brand name hman langsar zual thenkhat te:
Oriprim, Sulphatrim, Duaprim, Sulcoprim, Robatrim, Vetrim
LA, Intrim, Brimidine, Biotrim DS, Biotrim IM,etc.
Heng kan han tarlan bakah hian a dang tamtak antifungal
antibiotics kan tih te,miscellaneous group a dah theih antibiotic tamtak
an la awm bawk a ni. Kan hriat theuh angin damdawi hrechiang lo a
hman hian thiltam takah harsatna hrang hrang a thlen thei a,dam pui
aia thihpui hialna te pawh a thlen thei a,amaherawhchu a hmanna a
dik chuan damdawi tha tak tak te an ni hlawm a ni.
Tunah chuan damdawi group thenkhat kan hman lar deuhte a
tawikim thei ang berin Io tarlang leh i la.
VITAMINS : INJECTABLES
Sl no. Generic Name Brand Names Dosages
1. Sodium salt- Tonophosphan inj., Tphos LA- 1-3g (1.5dose IV, other
4-dimethylcobalamine, half S/C)
phosphorus,…. SA- 0.2-0.6g
2. Toldim phos Tonolon Same as above
3. Sodium acid phosphate Enphos, Vesphos, Aciphos, Urimin, LA- 3.2-6g on every alt. days
Sodaphos * 3days IM,IV,S/C
SA- 0.8-2.0 “
LA- 400-800mg
SA- 80-240mg
Dog&Cat- 80-100mg
LA- 25-50mg IM alt.days
SA- 0.2mg “
LA- 175mg,SA- 70-105mg
For 3-5 days
4. B-complex inj. Belamyl,Neuroxin M, Pinkojet, LA- 25-50mg IM on alt.days
Tribivet, Pinkoject L, Toxol, Bivinal * 3-5days
SA- 0.2-0.5mg “
LA- 175mg, SA- 70-105mg
5. Vitamin A,etc. Pinkojet, Veta A, Brivit, Cavit, LA- 5-10ml on alt.day
Intavita, Lavitone H SA- 2-3ml “
Sl no. Generic Name Brand Names Dosages
6. Calcium inj. Brical, Cal BD, Cobacol, Intacal IM Horse/cattle; Pig&sheep 60
I.U/kg/day on alt.days
Dog&cat- 66 I.U/kg/day
7. Iron Sorbital inj. Feritas, Imferon, Haemofen 0.3-0.4 ml I.M (SA)
0.5-1.0 ml I.M
10 ml/animal (LA) in severe
case
8. Liver extracts Belamyl, Tribivet, Livamyl, Pinkojet L Same as above in B-complex
inj.
9. Metabolic Diseases Calcimag, Miphocal, Lactomag, Intalyte LA- 200-300ml – 500ml
I.V therapy MA- 20-150ml
ANALGESICS : INJECTABLES + ORALS
Sl no. Generic Names Brand Names Dosages
1. Analgin / Metamizole Vetalgin LA- 10-30g, SA- 2.5-7.5g
2. Meloxicam Melonex, Melobest, Lofac M, LA- 0.5mg/kg IM
Lofac MP, A3 Vet inj. MA- 0.4mg/kg IM
Dog- 0.2mg/kg IM,SC
3. Diclofenac,Mefenamic Zobid,Xyclofen,Paralgin AP, 3D 1mg/kg deep IM in gluteal region
Vet, 3D Vet plus, Briclofen, LA- 500-750mg/day*3-4days
Feverdon SA- 50-75mg/day*3-4days
Dogs- 25-50mg/day*3-4days
4. Phenylbutazone,Analgin Esgipyrin N LA- 50-150mg Deep IM
SA- 10-50mg Deep IM
5. Tolfenamic Maxxtol LA- 2mg/kg to be repeated after
48 hours or 4mg/kg Single dose
IM+IV
Sheep&Pig- 2mg/kg Single dose
IM only
Horse- 2mg/kg Single dose IV
only
CORTICOSTEROIDS
GENERIC NAMES BRAND NAMES DOSAGES
Dexamethasone Dexona,Brisone Cattle- 4-10mg/kg I.M
Betamethasone Betnesol Dog- 0.25-5mg/kg IM
Triamcinolone Ecidex/Vetcort Cat- 0.25-2mg IM,IV
Glucocorticoid Prednisolone Brisone-
8-10mg(LA), 0.5-4mg(SA),
0.8-2mg(Dog),
10-20mg LA, 2-4mg SA
LA- 6-18mg, Dog- 0.05mg/kg
BID/TID I.M
LA- 0.5mg/kg, calf&pig- 2.5-
5ml TID
Dog&cat- 1-3ml (Total dose)
IVERMECTINS
GENERIC NAMES BRAND NAMES DOSAGES

Ivermectin Ivamec, Neomec, Parid, Mectin, LA- 1ml/40-50kg(only S/C)


Ivectin, Evidact, Trumectin, Hitek, SA- 1ml/20-33kg
Ecto-n, Endectin, Genimec, Alverin Dog- 1ml/10kg

ANTIHISTAMINES

GENERIC NAMES BRAND NAMES DOSAGES

Pheneramine Zect, Cadistin, Chloril, Sevil, LA- 5-10ml


maleate, Avil, ACM, Allergo Dog- 0.4-2mg/kg b.wt
Chlorphenaramine
maleate, Immolyte ‘C’ Dog- 5-10days TID orally,
Diphenhydramine Adult- 10-20 days TID
Hormone Preparation
Sl no. Generic Name Brand Names Dosages
1. Human Chorionic Chorulon L.A1500 I.U IM,IV
Gonadotropin
2. Buserelin Acetate Receptal Cattle0.02mg,
Horse,sheep&goat0.004m
g, IM,IV
3. Cloprostenol Sodium Cyclix Cow @2ml IM, Sow@1ml IM,
Prostaglandin F2-alpha Clostenol LA 263mcg/cow,
Pragma
Vetmate
ECTOPARASITICIDAL PREPARATIONS:

Sl no. Generic Name Brand Names Dosages


1. Deltamethrin Butox 1ml/lit water,
Tick2ml/lit water
Mite4ml/lit water
2. Amitraz Taktic, Fix-mange,Virtraz 4ml/lit water,
Cattle@2ml/lit water
3. Cypermethrin Pesticide, Tikkil 1ml/lit water; Animal
House @ 20ml/lit water
1g/lit water; Animal
House @ 20g/5lit water
ORAL ANTIBIOTICS & ANTIDIARRHOEALS
Sl no. Generic Name Brand Names Dosages

1. Cephalexin pd & bolus Lixen,ledexin,Malexin 1bol/150kg b.wt

2. Trimethoprim+Sulphomethoxazole+ Oriprim,Duaprim,Sulcoprim, Cotrimal bol.,Vetran LA, 1bol/50 kg b.wt


Sulphadiazine Genprim LA4 boli,
SA½ - 1 bol.
3. Sulphadiamidine Sulpha bol., Leucidine 100-200mg/kg½ dose daily (LA)
1g/5kg—0.5g/5kg daily 2 hourly
4. Oxytetracycline Oxy Vet, Steclin, Loxy

5. Norfloxacin+Tinidazole NT-zole 1-2 boli BID

6. Ofloxacin+Ornidazole Oford LA1000-2000mg


SA250-500mg
7. Ciprofloxacin+Tinidazole Griptol, CfloxTz, Genizole LA2 boli BID
SA½-1boli BID
8. Neomycin+Doxycycline Doemycin Parental @ 1g/10 lit water for 3-4
days
Prophylactic @ 1g/10lit water for 4-5
days
Acute @ 1g/5 lit water for 3-4 days
9. Enrofloxacin liq. Enrox, V-floxacin Preventive @ 2.5-5mg/kg,5-8 days
Treatment @ 10mg/kg,3-5 days
10. Amprolium Merycoxy-K,Amprosol Cattle@10mg/kg, Poultry@30g/50lit
water, Sheep&goat @25-45mg/kg
THANK YOU!!!

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